Aportación al estudio micosociológico de la provincia de León

Se muestran los resultados de algunas excursiones y el catálogo de las especies de macromicetes recolectadas en cada localidad.We show the results of some excursions with the catalogue of species rellected in each place

Bounds on the dipole moments of the tau-neutrino via the process e+e−→ννˉγe^{+}e^{-}\rightarrow \nu \bar \nu \gamma in a 331 model

We obtain limits on the anomalous magnetic and electric dipole moments of the $\nu_{\tau}$ through the reaction $e^{+}e^{-}\rightarrow \nu \bar \nu \gamma$ and in the framework of a 331 model. We consider initial-state radiation, and neglect $W$ and photon exchange diagrams. The results are based on the data reported by the L3 Collaboration at LEP, and compare favorably with the limits obtained in other models, complementing previous studies on the dipole moments.Comment: 13 pages, 4 figures, to be published in The European Physical J C. arXiv admin note: substantial text overlap with arXiv:hep-ph/060527

Células presentadoras de antígeno: células dendríticas y su papel en la lengua azul

Las células presentadoras de antígeno (CPA) desempeñan un papel fundamental en el desarrollo de la respuesta inmunitaria mediante el procesamiento y la presentación de antígenos, así como a través de distintos estímulos que favorecen la proliferación y diferenciación linfocitaria. Entre las CPA, las células dendríticas (CDs) son consideradas como las más eficientes en las funciones de presentación. En este trabajo se abordan aspectos generales relacionados con la localización, estructura y función de estas células, así como con su importante papel en la instauración de la repuesta inmunitaria. Junto a las células endoteliales y a los macrófagos, las CDs son consideradas células blanco del virus de la lengua azul (vLA), desempeñando un importante papel en la diseminación orgánica de éste. Además, las CDs parecen jugar un importante papel como productoras o inductoras de sustancias vasoactivas responsables de los cambios vasculares que caracterizan a la enfermedad, quedando aún por determinar la influencia de estos mediadores químicos en la instauración de la respuesta inmunológica frente al virus, aspecto fundamental para el desarrollo y mejora de vacunas

Response of alluvial systems to Late Pleistocene climate changes recorded by environmental magnetism in the Añavieja Basin (Iberian Range, NE Spain)

Environmental magnetic proxies were analyzed in a relatively monotonous, ~25.3m thick alluvial sedimentary sequence drilled in the Añavieja Basin (NE Spain). Results from the core AÑ2 suggest that the concentrationdependent magnetic parameters mainly reflect variations in the content of detrital magnetite, sourced in the catchment rocks and soils of the basin, via changes in the dynamics of alluvial fans due to temperature changes in the northern hemisphere during the Late Pleistocene. The correspondence between the magnetic proxies and the temperature variations in the North Atlantic region (NGRIP curve) indicates that higher (lower) concentrations and finer (coarser) magnetite grains coincide with warm (cold) periods. We propose that during cold periods, a sparser vegetation cover favored the incoming of higher energy runoff bearing coarser sediments to the basin that are relatively impoverished in magnetite. In contrast, during warm periods, the wider distribution of the vegetation cover associated with the lower runoff energy lead to finer, magnetite-richer sediment input to the basin. Maghemite, presumably of pedogenic origin, appears to be present also in the studied alluvial sediments. Further studies are necessary to unravel its palaeoclimatic significance

A functional variant in the stearoyl-CoA desaturase (SCD) gene promoter affects gene expression in ovine muscle

The nutritional quality of lambs may be improved with increased stearoyl-CoA desaturase (SCD) gene expression, which increases the desaturation of stearic acid to oleic acid. The aim of this study was to evaluate the effect of the rs412429481 (FJ513370: g.31C > A) SNP located at the SCD gene on the functionality of the gene in lambs reared under different production systems. The effect of the rs412429481 SNP on gene expression in Rasa Aragonesa male lambs slaughtered at 22–24 kg was studied in two experiments. In Experiment 1 (n = 44), the semitendinosus muscle of lambs grazing alfalfa (ALF) or fed concentrates indoors (IND) was analysed; in Experiment 2 (n = 48), the semitendinosus and longissimus thoracis muscles of lambs that received supplementation with dl-a-tocopheryl acetate for different finishing periods were used. In Experiment 1, the effect of the rs412429481 SNP on the expression of the SCD gene in the semitendinosus muscle depended on the feeding group (P < 0.001), as it had no effect in ALF lambs, but CA lambs had greater SCD expression than CC lambs under the IND conditions. Moreover, ALF lambs showed lower levels of SCD gene expression than IND lambs (P < 0.05). In Experiment 2, gene expression was affected by the rs412429481 SNP in both muscles. Animals carrying the C- allele showed a lower expression rate than animals carrying the A- allele. These different expression levels were not associated with changes in the DNA methylation pattern or by the binding of specific nuclear proteins. Finally, we confirmed these results by luciferase assays, demonstrating that the SCD promoter containing the A variant had a 23.9% higher activity than the promoter containing the C variant

Influencia en la cafeína sobre la motilidad, supervivencia y acrosomia espermática del semen descongelado de morueco

[ES] Influencia en la cafeína sobre la motilidad, supervivencia y acrosomia espermática del semen descongelado de moruec

Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices

Atrial electrical remodelling (AER) is a transitional period associated with the progression and long-term maintenance of atrial fibrillation (AF). We aimed to study the progression of AER in individual patients with implantable devices and AF episodes. Observational multicentre study (51 centres) including 4618 patients with implantable cardioverter-defibrillator and results þ/resynchronization therapy (ICD/CRT-D) and 352 patients (2 centres) with pacemakers (median follow-up: 3.4 years). Atrial activation rate (AAR) was quantified as the frequency of the dominant peak in the signal spectrum of AF episodes with atrial bipolar electrograms. Patients with complete progression of AER, from paroxysmal AF episodes to electrically remodelled persistent AF, were used to depict patient-specific AER slopes. A total of 34 712 AF tracings from 830 patients (87 with pacemakers) were suitable for the study. Complete progression of AER was documented in 216 patients (16 with pacemakers). Patients with persistent AF after completion of AER showed ∼30% faster AAR than patients with paroxysmal AF. The slope of AAR changes during AF progression revealed patient-specific patterns that correlated with the time-to-completion of AER (R = 0.85). Pacemaker patients were older than patients with ICD/CRT-Ds (78.3 vs. 67.2 year olds, respectively, P < 0.001) and had a shorter median time-to-completion of AER (24.9 vs. 93.5 days, respectively, P = 0.016). Remote transmissions in patients with ICD/CRT-D devices enabled the estimation of the time-to-completion of AER using the predicted slope of AAR changes from initiation to completion of electrical remodelling (R = 0.45). The AF progression shows patient-specific patterns of AER, which can be estimated using available remote-monitoring technology

Personalized monitoring of electrical remodelling during atrial fibrillation progression via remote transmissions from implantable devices

Aims: Atrial electrical remodelling (AER) is a transitional period associated with the progression and long-term maintenance of atrial fibrillation (AF). We aimed to study the progression of AER in individual patients with implantable devices and AF episodes. Methods and results: Observational multicentre study (51 centres) including 4618 patients with implantable cardioverter-defibrillator +/-resynchronization therapy (ICD/CRT-D) and 352 patients (2 centres) with pacemakers (median follow-up: 3.4 years). Atrial activation rate (AAR) was quantified as the frequency of the dominant peak in the signal spectrum of AF episodes with atrial bipolar electrograms. Patients with complete progression of AER, from paroxysmal AF episodes to electrically remodelled persistent AF, were used to depict patient-specific AER slopes. A total of 34 712 AF tracings from 830 patients (87 with pacemakers) were suitable for the study. Complete progression of AER was documented in 216 patients (16 with pacemakers). Patients with persistent AF after completion of AER showed ∼30% faster AAR than patients with paroxysmal AF. The slope of AAR changes during AF progression revealed patient-specific patterns that correlated with the time-to-completion of AER (R2 = 0.85). Pacemaker patients were older than patients with ICD/CRT-Ds (78.3 vs. 67.2 year olds, respectively, P < 0.001) and had a shorter median time-to-completion of AER (24.9 vs. 93.5 days, respectively, P = 0.016). Remote transmissions in patients with ICD/CRT-D devices enabled the estimation of the time-to-completion of AER using the predicted slope of AAR changes from initiation to completion of electrical remodelling (R2 = 0.45). Conclusion: The AF progression shows patient-specific patterns of AER, which can be estimated using available remote-monitoring technology