Opening up the Quantum Three-Box Problem with Undetectable Measurements

One of the most striking features of quantum mechanics is the profound effect exerted by measurements alone. Sophisticated quantum control is now available in several experimental systems, exposing discrepancies between quantum and classical mechanics whenever measurement induces disturbance of the interrogated system. In practice, such discrepancies may frequently be explained as the back-action required by quantum mechanics adding quantum noise to a classical signal. Here we implement the 'three-box' quantum game of Aharonov and Vaidman in which quantum measurements add no detectable noise to a classical signal, by utilising state-of-the-art control and measurement of the nitrogen vacancy centre in diamond. Quantum and classical mechanics then make contradictory predictions for the same experimental procedure, however classical observers cannot invoke measurement-induced disturbance to explain this discrepancy. We quantify the residual disturbance of our measurements and obtain data that rule out any classical model by > 7.8 standard deviations, allowing us for the first time to exclude the property of macroscopic state-definiteness from our system. Our experiment is then equivalent to a Kochen-Spekker test of quantum non-contextuality that successfully addresses the measurement detectability loophole

Field enhancement and spectral features of hexagonal necklaces of silver nanoparticles for enhanced nonlinear optical processes

Access to the online abstract in the journal: https://doi.org/10.1364/OE.26.022394 © 2018 Optical Society of America. Users may use, reuse, and build upon the article, or use the article for text or data mining, so long as such uses are for non-commercial purposes and appropriate attribution is maintained. All other rights are reservedThe nonlinear properties of hybrid metallic-dielectric systems are attracting great interest due to their potential for the enhancement of frequency conversion processes at nanoscale dimensions. In this work, we theoretically and experimentally address the correlation between the near field distribution of hexagonal plasmonic necklaces of silver nanoparticles formed on the surface of a LiNbO3 crystal and the second harmonic generation (SHG) produced by this nonlinear crystal in the vicinities of the necklaces. The spectral response of the hexagonal necklaces does not depend on the polarization direction and is characterized by two main modes, the absorptive high-energy mode located in the UV spectral region and the lower energy mode, which is strongly radiant and extends from the visible to the near infrared region. We show that the spatial distribution of the enhanced SHG is consistent with the local field related to the low energy plasmon mode, which spectrally overlaps the fundamental beam. The results are in agreement with the low absorption losses of this mode and the two-photon character of the nonlinear process and provide deeper insight in the connection between the linear and nonlinear optical properties of the hybrid plasmonic-ferroelectric system. The study also highlights the potential of hexagonal necklaces as useful plasmonic platforms for enhanced optical processes at the nanoscaleSpanish Ministry of Economy and Competitiveness (MINECO) under project MAT2016- 76106-R and the Comunidad de Madrid (grant S2013/MIT-2740). C.T. acknowledges funding from the VILLUM Foundation (Villum Investigator, grant no. 16498). L.E.B and M.O.R also acknowledges financial support from the Spanish Ministry of Economy and Competitiveness, through The “María de Maeztu” Programme for Units of Excellence in R&D (MDM-2014-0377

Políticas del blanqueamiento: escenografías del despojo urbano en Guadalajara

En este trabajo nos proponemos describir y problematizar el papel que juegan las políticas culturales en las estrategias de especulación y elitización del territorio en los centros históricos. Procesos que, a su vez, tienen como una de sus consecuencias más importantes la segregación racial y de clase en las metrópolis contemporáneas. Para ello, analizamos el caso concreto del Centro Histórico de Guadalajara desde una mirada que articula diversos actores y proyectos culturales, inmobiliarios y vecinales, así como sus implicaciones en las dinámicas urbanas del centro y la periferia

Major gene expression changes and epigenetic remodelling in Nile tilapia muscle after just one generation of domestication

The historically recent domestication of fishes has been essential to meet the protein demands of a growing human population. Selection for traits of interest during domestication is a complex process whose epigenetic basis is poorly understood. Cytosine hydroxymethylation is increasingly recognized as an important DNA modification involved in epigenetic regulation. In the present study, we investigated if hydroxymethylation plays a role in fish domestication and demonstrated for the first time at a genome-wide level and single nucleotide resolution that the muscle hydroxymethylome changes after a single generation of Nile tilapia (Oreochromis niloticus, Linnaeus) domestication. The overall decrease in hydroxymethylcytosine levels was accompanied by the downregulation of 2015 genes in fish reared in captivity compared to their wild progenitors. In contrast, several myogenic and metabolic genes that can affect growth potential were upregulated. There were 126 differentially hydroxymethylated cytosines between groups, which were not due to genetic variation; they were associated with genes involved in immune-, growth- and neuronal-related pathways. Taken together, our data unveil a new role for DNA hydroxymethylation in epigenetic regulation of fish domestication with impact in aquaculture and implications in artificial selection, environmental adaptation and genome evolution

Estudio sistemático, morfométrico y biogeográfico de <i>Blainia gregaria</i> Walcott, trilobite cámbrico medio de la Precordillera argentina

Se reconoce por primera vez en la Precordillera argentina el trilobite Blainia gregaria Walcott, del Cámbrico medio (Series 3). Los ejemplares estudiados fueron hallados en el tramo superior de la Formación La Laja, con litofacies de plataforma carbonática, aflorante en la Precordillera Oriental de San Juan. El presente trabajo se basa en dos perfiles ubicados en el cerro Tres Marías (sierra de Marquesado), y en la quebrada de Zonda (sierra Chica de Zonda). Los trilobites coleccionados están compuestos por 1.202 ejemplares (632 de la quebrada de Zonda y 570 del cerro Tres Marías) integrados por 563 pigidios y 639 cranidios. El estudio biométrico realizado en los especímenes precordilleranos de Blainia gregaria se basó en la colección del cerro Tres Marías (205 cranidios y 365 pigidios), hallada en 22 niveles estratigráficos distribuidos a lo largo de 155m de espesor columnar (15m cuspidales del Miembro Soldano, 100m del Miembro Rivadavia y 40m basales del Miembro Juan Pobre). El análisis morfométrico muestra relaciones bivariables que dan una nube de puntos muy similares, con rectas de regresión únicas, con los coeficientes de correlación bajos, que son compatibles con la idea de variabilidad intraespecífica. Se reconocen 6 morfotipos (3 cranidios y 3 pigidios) que aparecen juntos en la misma colección. Esto evidencia que es una especie extraordinariamente polimórfica, y nos lleva a proponer una extensa lista sinonímica con más de 30 especies de América del Norte, anteriormente agrupadas en los géneros Blainia Walcott y Glyphaspis Poulsen. La distribución biogeográfica de Blainia gregaria, así redefinida, muestra que esta especie poseía una amplia tolerancia ecológica a los diversos ambientes de las plataformas carbonáticas que rodeaban a Laurentia durante el Cámbrico medio. Su presencia en Precordillera es una evidencia de la estrecha relación que tiene el Terrane Precordillera con Laurentia.Simposio I: 2º Simposio de bioestratigrafía y eventos del Paleozoico inferiorFacultad de Ciencias Naturales y Muse

Clinical factors associated with high glycemic variability defined by coefficient of variation in patients with type 2 diabetes

Antecedentes: La Variabilidad Glucémica Alta (VHG) ha convertirse en un predictor más fuerte de hipoglucemia. Sin embargo, aún se desconocen los factores clínicos asociados con el VHG. Objetivo:Determinar las variables clínicas que se asociaron con un coeficiente de variación (CV) superior al 36% evaluado mediante monitorización continua de glucosa (MCG) en un grupo de pacientes con diabetes mellitus. Métodos: Se evaluó una cohorte de pacientes con diabetes tipo 2 (T2D). Se evaluaron variables demográficas, HbA1c, tasa de filtración glomerular (TFG) y régimen de tratamiento. Se realizó un análisis bivariado, para evaluar la asociación entre la variable resultado (CV > 36%) y cada una de las variables independientes. Se construyó un modelo multivariado para evaluar las asociaciones después de controlar las variables de confusión. Resultados:Se analizaron los datos de MCG de 274 pacientes. CV> 36% estuvo presente en 56 pacientes (20,4%). En el análisis bivariado se incluyeron variables demográficas y clínicas, como tiempo desde el diagnóstico, antecedente de hipoglucemia, A1c, FG y tratamiento instaurado. En el análisis multivariante, FG 9% (OR 2,81; IC 1,05,7,51; p:0,04) y antecedentes de hipoglucemia (OR 2,09; IC 1,02, 4,32; p: 0,04) se asociaron con VHG. El tratamiento con iDPP4 (OR 0,39; IC 0,19, 0,82; p: 0,01) y AGLP1 (OR 0,08; IC 0,01, 0,68; p: 0,02) se asoció inversamente con la VG. Conclusión:Variables clínicas como FG 9% y antecedentes de hipoglucemia se asocian a un VG alto. Nuestros datos sugieren que el uso de tecnología y tratamientos capaces de reducir la variabilidad glucémica podría ser útil en esta población para reducir el riesgo de hipoglucemia y mejorar el control glucémico.Q3Background: High glycemic Variability (HGV) has become a stronger predictor of hypoglycemia. However, clinical factors associate with HGV still are unknown. Objective: To determine clinical variables that were associated with a coefficient of variation (CV) above 36% evaluated by continuous glucose monitoring (CGM) in a group of patients with diabetes mellitus. Methods: A cohort of patients with type 2 diabetes (T2D) was evaluated. Demographic variables, HbA1c, glomerular filtration rate (GFR) and treatment regimen were assessed. A bivariate analysis was performed, to evaluate the association between the outcome variable (CV> 36%) and each of the independent variables. A multivariate model was constructed to evaluate associations after controlling for confounding variables. Results: CGM data from 274 patients were analyzed. CV> 36% was present in 56 patients (20.4%). In the bivariate analysis, demographic and clinical variables were included, such as time since diagnosis, hypoglycemia history, A1c, GFR and treatment established. In the multivariate analysis, GFR 9% (OR 2.81; CI 1.05,7.51; p:0.04) and hypoglycemia history (OR 2.09; CI 1.02,4.32; p:0.04) were associated with HGV. Treatment with iDPP4 (OR 0.39; CI 0.19,0.82; p:0.01) and AGLP1 (OR 0.08; CI 0.01,0.68; p:0.02) was inversely associated with GV. Conclusion: Clinical variables such as GFR 9% and a history of hypoglycemia are associated with a high GV. Our data suggest that the use of technology and treatments able to reduce glycemic variability could be useful in this population to reduce the risk of hypoglycemia and to improve glycemic control.Revista Internacional - Indexad

Sistematización del proceso de adaptación y montaje teatral del cuento el cocodrilo de Fiódor Dostoievski.

Esta monografía se realiza con el propósitos de sistematizar y dejar documentado el proceso de creación y ejecución de la adaptación de la obra el Cocodrilo de Fiódor Dostoievski, a cargo de la maestra Johana Robledo, docente del taller de montaje IV; además de plasmar por escrito el paso a paso del proceso de un montaje para que estudiantes y profesores de Licenciatura en Arte Dramático o personas ajenas a la carrera, tengan un documentos escrito que les sirva para poder ejecutar sus propios montajes , así mismo para tener memoria de un referente artístico que de cuenta de los procesos académicos que se realizan en la carrer

Enhanced sequential carrier capture into individual quantum dots and quantum posts controlled by surface acoustic waves

Individual self-assembled Quantum Dots and Quantum Posts are studied under the influence of a surface acoustic wave. In optical experiments we observe an acoustically induced switching of the occupancy of the nanostructures along with an overall increase of the emission intensity. For Quantum Posts, switching occurs continuously from predominantely charged excitons (dissimilar number of electrons and holes) to neutral excitons (same number of electrons and holes) and is independent on whether the surface acoustic wave amplitude is increased or decreased. For quantum dots, switching is non-monotonic and shows a pronounced hysteresis on the amplitude sweep direction. Moreover, emission of positively charged and neutral excitons is observed at high surface acoustic wave amplitudes. These findings are explained by carrier trapping and localization in the thin and disordered two-dimensional wetting layer on top of which Quantum Dots nucleate. This limitation can be overcome for Quantum Posts where acoustically induced charge transport is highly efficient in a wide lateral Matrix-Quantum Well.Comment: 11 pages, 5 figure

Performance of the 2007 WHO Algorithm to diagnose Smear-negative Pulmonary Tuberculosis in a HIV prevalent setting

The 2007 WHO algorithm for diagnosis of smear-negative pulmonary tuberculosis (PTB) including Mycobacterium tuberculosis (MTB) culture was evaluated in a HIV prevalent area of Kenya

Síntesis de biolubricantes biodegradables a partir de aceite de soya

Se estudió la polimerización catalítica oxidativa de aceites naturales para la producción de lubricantes de presión extrema mediante FTIR y la medición de viscosidad. Se variaron los parámetros: 1) Concentración y tipo de catalizador, 2) velocidad de agitación y 3) la temperatura; durante la síntesis. A partir del índice de viscosidad se propone un modelo de predicción del peso molecular del aceite polimerizado. Los resultados confirman un alto grado de ajuste para el modelo propuesto. La viscosidad del aceite polimerizado varía desde los 30 cSt hasta los 11,000 cSt. La viscosidad del polímero depende primordialmente de la velocidad de agitación, del tipo de catalizador y de la temperatura de polimerización, y en mucha menor proporción de la concentración del catalizador.Catalytic oxidative polymerization of natural oils was studied for the production of extreme pressure lubricants. Some variables were explored during the synthesis such as: 1) catalyst concentration and 2) Stirring rate. The course of reaction was followed by FTIR, refraction index and viscosity measurements of products. A prediction model of the molecular weight of the polymerized oil is proposed from viscosity indexes. Results confirm a high degree of fit for the proposed model. Polymerized oil viscosities range from 30 cSt to and 11, 000 cSt. The viscosity depends primarily on the rate of agitation, the type of catalyst and the polymerization temperature, and to a much smaller proportion of the catalyst concentration