Nuevas citas de Monocotiledóneas para la provincia de Granada (Sur de España)

New floristic records of Monocotyledons for Granada province (S Spain).Palabras clave. Corología, Monocotiledóneas, Granada. Key words. Corology, Monocotyledons, Granada, Spain

Nuevas citas para la provincia de Granada (Andalucía, España)

New cites for Granada province (Spain).Palabras clave. Guadix-Baza, corologfa, ecología.Key words. Guadix-Baza, corology, ecology

Resilience amongst Older Colombians Living in Poverty: an Ecological Approach.

Older Colombians face significant adversities: poverty, violence and displacement. However, there is evidence that Latinos are often resilient. We examine resilience in older Colombians living in poverty using an ecological framework that identifies three levels: individual; community; and societal. In this paper we examine data from 16 semi-structured interviews with older Colombians that explore resilience within the context of poverty. We analyze our data using three stages: (1) modified grounded theory; (2) assignment of resilience status; (3) identification of components of the ecological framework which contribute to resilience in these participants. The most striking feature is that some participants are able to adapt to their situation, demonstrating resilience, whilst others are not. Individual characteristics such as psychological and material resources contribute to resilience. At the community level, family, social support, participation and cohesion promote resilience. Finally, at the societal level, social and welfare services, finance, religion and social policy, are important factors. These different levels of resilience are co-dependent, and we illustrate how this is so. We suggest that older Colombians living in poverty often demonstrate resilience, but that more can be done to enhance their lives. This includes interventions at the individual and community levels alongside changes in social policy

Design of the Front End Electronics for the Infrared Camera of JEM-EUSO, and manufacturing and verification of the prototype model

The Japanese Experiment Module (JEM) Extreme Universe Space Observatory (EUSO) will be launched and attached to the Japanese module of the International Space Station (ISS). Its aim is to observe UV photon tracks produced by ultra-high energy cosmic rays developing in the atmosphere and producing extensive air showers. The key element of the instrument is a very wide-field, very fast, large-lense telescope that can detect extreme energy particles with energy above $10^{19}$ eV. The Atmospheric Monitoring System (AMS), comprising, among others, the Infrared Camera (IRCAM), which is the Spanish contribution, plays a fundamental role in the understanding of the atmospheric conditions in the Field of View (FoV) of the telescope. It is used to detect the temperature of clouds and to obtain the cloud coverage and cloud top altitude during the observation period of the JEM-EUSO main instrument. SENER is responsible for the preliminary design of the Front End Electronics (FEE) of the Infrared Camera, based on an uncooled microbolometer, and the manufacturing and verification of the prototype model. This paper describes the flight design drivers and key factors to achieve the target features, namely, detector biasing with electrical noise better than $100 \mu$V from $1$ Hz to $10$ MHz, temperature control of the microbolometer, from $10^{\circ}$C to $40^{\circ}$C with stability better than $10$ mK over $4.8$ hours, low noise high bandwidth amplifier adaptation of the microbolometer output to differential input before analog to digital conversion, housekeeping generation, microbolometer control, and image accumulation for noise reduction

Pumping Iron - How Do Race and Gender Affect the Risk of Anemia in a Cohort of Predominantly Hispanic Heart Failure (HF) Patients Seen in a Community Hospital in the Rio Grande Valley (RGV)?

Introduction Anemia in patients with heart failure (HF) is common. Data reported shows a variable prevalence ranging from 10-40%. Additionally, it has also been demonstrated that it is associated with poor outcomes. Multiple risk factors have been shown to contribute to the presence of anemia in HF patients (1). We were interested in determining the risk factors for anemia in HF patients in our population in the lower Rio Grande Valley. Methods We performed a retrospective chart review of patients admitted with a diagnosis of HF (Heart Failure with Preserved Ejection Fraction HFpEF, Heart Failure with Reduced Ejection Fraction HFrEF or combined) during the year 2017 to our community hospital. Patients’ charts were reviewed for multimorbidities, laboratory data, and anemia treatments. Outcomes were assessed as readmissions and death within 1 year from index admission. Definitions were used according to preestablished guidelines. Statistical analysis was done using Minitab software and univariate and multivariate logistic regression analysis. Results A total of 320 patients were evaluated. The average age was 71 14, 121 (38%) were female, 229 (72%) were Hispanics, and average BMI was 31 7. 118 (37%) patients had HFrEF and 102 (32%) had HFpEF. 218 (68%) had coronary artery disease, 280 (88%) hypertension, 188 (59%) diabetes mellitus, 149 (47%) chronic kidney disease, and 102 (32%) atrial fibrillation. Of 320 patients that were evaluated, 185 (58%) had anemia with a mean hemoglobin level of 10 1 mg/dl. The major risk factors for anemia in our patient population were Hispanic race with an odds ratio (OR) of 1.8 (CI 1.01-2.3) p-value 0.03, HFpEF with an OR 1.6 (CI 1.2-2.6) p-value 0.04, female gender OR 2.3 (1.42-3.74) p-value 0.0007, and CKD with an OR 2.6 (CI 1.6-3.0) p-value 0.001 - all adjusted to age. Obesity and its different classifications was not a risk factor for anemia. Mortality and readmission rates were higher in patients with anemia (5.4% vs 2.9% and 34% vs 31%, respectively). Conclusions We found that women were more likely to have anemia than men, confirming previous observations (2). Additionally, Hispanics were more likely than non-Hispanics to have anemia, which has been suggested in previous studies (3). This probably accounts for the high prevalence of anemia in our patient population. We had anticipated that obesity would be a risk factor, but thorough analysis of the data could not detect any increase in anemia no matter the degree of obesity. We believe that further studies are warranted to evaluate this subset of HF patients since they are at higher risk of worse outcomes and to determine whether treating the anemia reduces negative outcomes such as death and readmission

Propiedades psicométricas de la Escala de Motivación Académica de los Adolescentes (EMAA) en una muestra representativa de estudiantes de instituto de la República Dominicana

Within the growing body of research that has focused on academic success, academic motivation has gathered considerable attention. The aim of this this research is to present the first validation of the Adolescents’ Academic Motivation Scale (AAMS). Total sample was composed by 1712 students of secondary education from two districts in the Dominican Republic. The main measurement outcome was the AAMS. Results from the CFA were satisfactory: χ2(5) = 57.73, p < .001; CFI = .970; RMSEA = .079 [.061, .097], and SRMR = .024. IRT analyses favored the two-parameter logistic model, indicating that items were not equally discriminant. Structural Equation Model with latent variables in which academic motivation was a significant predictor of grades resulted in excellent fit: χ2(53) = 182.76, p < .001; CFI = .980; RMSEA = .038 90% CI [.032, .044], and SRMR = .025. In sum, this work presents an exhaustive psychometric analysis of the AAMS in a representative sample of high school Dominican students.Entre el creciente cuerpo de investigación que se ha centrado en el éxito académico, la motivación académica ha captado considerable atención. El objetivo de esta investigación es presentar la primera validación de la Escala de Motivación Académica de los Adolescentes (EMAA). La muestra total estuvo compuesta por 1712 estudiantes de secundaria de dos distritos de la República Dominicana. La medida principal fue la EMAA. Los resultados del AFC fueron satisfactorios: χ2(5) = 57.73, p < .001; CFI = .970; RMSEA = .079, 90% CI [.061, .097], y SRMR = .024. Los análisis de TRI favorecieron al modelo logístico de dos parámetros, indicando que los ítems no fueron igualmente discriminativos. El Modelo de Ecuaciones Estructurales en el que la motivación académica predecía de forma estadísticamente significativa las calificaciones obtuvo un ajuste excelente: χ2(53) = 182.76, p < .001; CFI = .980; RMSEA = .038 [.032, .044], and SRMR = .025. En resumen, este trabajo presenta un exhaustivo análisis psicométrico de la EMAA en una muestra representativa de estudiantes dominicanos de instituto

Environmental and human factors drive the subtropical marine forests of Gongolaria abies-marina to extinction

Large brown macroalgae are foundational threatened species in coastal ecosystems from the subtropical northeastern Atlantic, where they have exhibited a drastic decline in recent years. This study describes the potential habitat of Gongolaria abies-marina, its current distribution and conservation status, and the major drivers of population decline. The results show a strong reduction of more than 97% of G. abies-marina populations in the last thirty years and highlight the effects of drivers vary in terms of spatial heterogeneity. A decrease in the frequency of high waves and high human footprint are the principal factors accounting for the long-term decline in G. abies-marina populations. UV radiation and sea surface temperature have an important correlation only in certain locations. Both the methodology and the large amount of data analyzed in this study provide a valuable tool for the conservation and restoration of threatened macroalgae.En prensa1,95

Expression, regulation and clinical relevance of the ATPase Inhibitory Factor 1 (IF1) in human cancers

Recent findings in colon cancer cells indicate that inhibition of the mitochondrial H(+)-adenosine triphosphate (ATP) synthase by the ATPase inhibitory factor 1 (IF1) promotes aerobic glycolysis and a reactive oxygen species (ROS)-mediated signal that enhances proliferation and cell survival. Herein, we have studied the expression, biological relevance, mechanism of regulation and potential clinical impact of IF1 in some prevalent human carcinomas. We show that IF1 is highly overexpressed in most (>90%) of the colon (n=64), lung (n=30), breast (n=129) and ovarian (n=10) carcinomas studied as assessed by different approaches in independent cohorts of cancer patients. The expression of IF1 in the corresponding normal tissues is negligible. By contrast, the endometrium, stomach and kidney show high expression of IF1 in the normal tissue revealing subtle differences by carcinogenesis. The overexpression of IF1 also promotes the activation of aerobic glycolysis and a concurrent ROS signal in mitochondria of the lung, breast and ovarian cancer cells mimicking the activity of oligomycin. IF1-mediated ROS signaling activates cell-type specific adaptive responses aimed at preventing death in these cell lines. Remarkably, regulation of IF1 expression in the colon, lung, breast and ovarian carcinomas is exerted at post-transcriptional levels. We demonstrate that IF1 is a short-lived protein (t(1/2) ∼100 min) strongly implicating translation and/or protein stabilization as main drivers of metabolic reprogramming and cell survival in these human cancers. Analysis of tumor expression of IF1 in cohorts of breast and colon cancer patients revealed its relevance as a predictive marker for clinical outcome, emphasizing the high potential of IF1 as therapeutic target

Experimental Zika Virus Infection in the Pregnant Common Marmoset Induces Spontaneous Fetal Loss and Neurodevelopmental Abnormalities.

During its most recent outbreak across the Americas, Zika virus (ZIKV) was surprisingly shown to cause fetal loss and congenital malformations in acutely and chronically infected pregnant women. However, understanding the underlying pathogenesis of ZIKV congenital disease has been hampered by a lack of relevant in vivo experimental models. Here we present a candidate New World monkey model of ZIKV infection in pregnant marmosets that faithfully recapitulates human disease. ZIKV inoculation at the human-equivalent of early gestation caused an asymptomatic seroconversion, induction of type I/II interferon-associated genes and proinflammatory cytokines, and persistent viremia and viruria. Spontaneous pregnancy loss was observed 16-18 days post-infection, with extensive active placental viral replication and fetal neurocellular disorganization similar to that seen in humans. These findings underscore the key role of the placenta as a conduit for fetal infection, and demonstrate the utility of marmosets as a highly relevant model for studying congenital ZIKV disease and pregnancy loss

Native Chilean Fruits and the Effects of their Functional Compounds on Human Health

In recent years, there has been great interest in the nutraceutical compounds of fruits from native Chilean plant species. In this context, fruits of Amomyrtus meli (Meli), Aristotelia chilensis (Maqui), Berberis microphylla (Calafate), Luma apiculata (Arrayán), Luma chequén (Chequén), and Ugni molinae (Murtilla) growing predominantly in Chilean forests have been studied. This chapter has compiled the existing information about antioxidant activity and antioxidant compound contents of the above mentioned fruit species and their association with the prevention of pathophysiological disorders in humans, such as inflammation, diabetes, and cardiovascular diseases. Results show that the antioxidant compounds of these species, particularly anthocyanins, decrease inflammation as well as the risk of diabetes and cardiovascular diseases. Therefore, consumption of these fruits is a good alternative for preventing cardiovascular and age-related diseases and pathophysiological disorders