710 research outputs found
Universality in two-dimensional Kardar-Parisi-Zhang growth
We analyze simulations results of a model proposed for etching of a
crystalline solid and results of other discrete models in the 2+1-dimensional
Kardar-Parisi-Zhang (KPZ) class. In the steady states, the moments W_n of
orders n=2,3,4 of the heights distribution are estimated. Results for the
etching model, the ballistic deposition (BD) model and the
temperature-dependent body-centered restricted solid-on-solid model (BCSOS)
suggest the universality of the absolute value of the skewness S = W_3 /
(W_2)^(3/2) and of the value of the kurtosis Q = W_4 / (W_2)^2 - 3. The sign of
the skewness is the same of the parameter \lambda of the KPZ equation which
represents the process in the continuum limit. The best numerical estimates,
obtained from the etching model, are |S| = 0.26 +- 0.01 and Q = 0.134 +- 0.015.
For this model, the roughness exponent \alpha = 0.383 +- 0.008 is obtained,
accounting for a constant correction term (intrinsic width) in the scaling of
the squared interface width. This value is slightly below previous estimates of
extensive simulations and rules out the proposal of the exact value \alpha=2/5.
The conclusion is supported by results for the ballistic deposition model.
Independent estimates of the dynamical exponent and of the growth exponent are
1.605 <= z <= 1.64 and \beta = 0.229 +- 0.005, respectively, which are
consistent with the relations \alpha + z = 2 and z = \alpha / \beta.Comment: 8 pages, 9 figures, to be published in Phys. Rev.
Lithium intercalation in nanostructured thin films of a mixed-valence layered vanadium oxide using an ionic liquid electrolyte
AbstractNanostructured thin films of a mixed-valence, layered vanadium oxide were prepared using layer-by-layer deposition. The thin films were characterized by electronic (UVâvis) spectroscopy, quartz crystal microbalance, profilometry and scanning electron microscopy techniques. The highest charge capacity was obtained for films that consisted of 25 bilayers. The electrochemical characterization of the films was performed in conventional organic solvent and ionic liquid (IL) based electrolytes. The results revealed better performance, in terms of stability during consecutive charge/discharge cycles, when ILs were employed. This can be attributed to several factors, including reduced mechanical stress caused by insertion of more than 1Â mol of Li+ per mol of V5+ in the film structure, decrease of crystallinity in the electrode material during the first few charge/discharge cycles and/or formation of a more compatible SEI. Nanostructured thin films of layered vanadium oxide prepared using layer-by-layer deposition showed potential for applications in lithium microbatteries
Crossover effects in a discrete deposition model with Kardar-Parisi-Zhang scaling
We simulated a growth model in 1+1 dimensions in which particles are
aggregated according to the rules of ballistic deposition with probability p or
according to the rules of random deposition with surface relaxation (Family
model) with probability 1-p. For any p>0, this system is in the
Kardar-Parisi-Zhang (KPZ) universality class, but it presents a slow crossover
from the Edwards-Wilkinson class (EW) for small p. From the scaling of the
growth velocity, the parameter p is connected to the coefficient of the
nonlinear term of the KPZ equation, lambda, giving lambda ~ p^gamma, with gamma
= 2.1 +- 0.2. Our numerical results confirm the interface width scaling in the
growth regime as W ~ lambda^beta t^beta, and the scaling of the saturation time
as tau ~ lambda^(-1) L^z, with the expected exponents beta =1/3 and z=3/2 and
strong corrections to scaling for small lambda. This picture is consistent with
a crossover time from EW to KPZ growth in the form t_c ~ lambda^(-4) ~ p^(-8),
in agreement with scaling theories and renormalization group analysis. Some
consequences of the slow crossover in this problem are discussed and may help
investigations of more complex models.Comment: 16 pages, 7 figures; to appear in Phys. Rev.
Acoustic instrumentation for a bubble chamber towards dark matter searches
Dark matter is one of the top unsolved mysteries in physics. Its existence is well-established although its nature remains unknown. Despite the progress made in the direct search effort, reflecting over 10 orders of magnitude in sensitivity since 1984, no true candidates to explain this phenomenon have appeared in searches covering a range from ~10 GeV to 1 TeV. This article reports on the development of a 1 kg freon bubble chamber prototype, including the chamber recompression system design and testing, initial acoustic detection of bubble formation, and initial neutron and alpha detector response studies. The prototype constructed was a transparent acrylic containment vessel, capable of withstanding recompression cycles to a pressure of 16 bar. The acoustic signal accompanying bubble formation was investigated using three different sensors: a low frequency microphone (Panasonic) with a flat response over 0.020-16 kHz, an ultrasound externallypolarized condenser microphone (AviSoft) with a flat response over 10-150 kHz, and an hydrophone (Reson) with a flat response over 5-170 kHz. Acoustic signatures of several induced events were successfully registered. The data acquisition digitizer used, to meet the range of the three microphones, was the NI PCI-6251 16-Bit, with at least 1.25 MSps for 1-Channel
Asymmetries between the production of D+ and D- mesons from 500 GeV/c pi- nucleon interactions as a function of xF and pt**2
We present asymmetries between the production of D+ and D- mesons in Fermilab
experiment E791 as a function of xF and pt**2. The data used here consist of
74,000 fully-reconstructed charmed mesons produced by a 500 GeV/c pi- beam on C
and Pt foils. The measurements are compared to results of models which predict
differences between the production of heavy-quark mesons that have a light
quark in common with the beam (leading particles) and those that do not
(non-leading particles). While the default models do not agree with our data,
we can reach agreement with one of them, PYTHIA, by making a limited number of
changes to parameters used
Mass Splitting and Production of and Measured in N Interactions
From a sample of decaying to the
final state, we have observed, in the hadroproduction experiment E791 at
Fermilab, and through
their decays to . The mass difference ) is measured to be ; for
, we find .
The rate of production from decays of the triplet is
(22\pm 2\pm 3) {%} of the total production assuming equal rate
of production from all three, as measured for and .
We do not observe a statistically significant baryon-antibaryon
production asymmetry. The and spectra of from
decays are observed to be similar to those for all 's
produced.Comment: 15 pages, uuencoded postscript 3 figures uuencoded, tar-compressed
fil
Physical characterization of a watershed through GIS: a study in the Schmidt stream, Brazil
Strategic orientations and cooperation of external agents in the innovation process of rural enterprises
ST6Gal1 targets the ectodomain of ErbB2 in a site-specific manner and regulates gastric cancer cell sensitivity to trastuzumab
The clinical performance of the therapeutic monoclonal antibody trastuzumab in the treatment of ErbB2-positive unresectable gastric cancer (GC) is severely hampered by the emergence of molecular resistance. Trastuzumab's target epitope is localized within the extracellular domain of the oncogenic cell surface receptor tyrosine kinase (RTK) ErbB2, which is known to undergo extensive N-linked glycosylation. However, the site-specific glycan repertoire of ErbB2, as well as the detailed molecular mechanisms through which specific aberrant glycan signatures functionally impact the malignant features of ErbB2-addicted GC cells, including the acquisition of trastuzumab resistance, remain elusive. Here, we demonstrate that ErbB2 is modified with both alpha 2,6- and alpha 2,3-sialylated glycan structures in GC clinical specimens. In-depth mass spectrometry-based glycomic and glycoproteomic analysis of ErbB2's ectodomain disclosed a site-specific glycosylation profile in GC cells, in which the ST6Gal1 sialyltransferase specifically targets ErbB2 N-glycosylation sites occurring within the receptor's trastuzumab-binding domain. Abrogation of ST6Gal1 expression reshaped the cellular and ErbB2-specific glycomes, expanded the cellular half-life of the ErbB2 receptor, and sensitized ErbB2-dependent GC cells to trastuzumab-induced cytotoxicity through the stabilization of ErbB dimers at the cell membrane, and the decreased activation of both ErbB2 and EGFR RTKs. Overall, our data demonstrates that ST6Gal1-mediated aberrant alpha 2,6-sialylation actively tunes the resistance of ErbB2-driven GC cells to trastuzumab.Proteomic
Anisotropy studies around the galactic centre at EeV energies with the Auger Observatory
Data from the Pierre Auger Observatory are analyzed to search for
anisotropies near the direction of the Galactic Centre at EeV energies. The
exposure of the surface array in this part of the sky is already significantly
larger than that of the fore-runner experiments. Our results do not support
previous findings of localized excesses in the AGASA and SUGAR data. We set an
upper bound on a point-like flux of cosmic rays arriving from the Galactic
Centre which excludes several scenarios predicting sources of EeV neutrons from
Sagittarius . Also the events detected simultaneously by the surface and
fluorescence detectors (the `hybrid' data set), which have better pointing
accuracy but are less numerous than those of the surface array alone, do not
show any significant localized excess from this direction.Comment: Matches published versio
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