12 research outputs found

    Use of computed tomography imaging during long-term follow-up of nine feline tuberculosis cases

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    Case series summary: Feline tuberculosis is an increasingly recognised potential zoonosis of cats. Treatment is challenging and prognosis can vary greatly between cases. Pulmonary infection requires extended courses of antibiotics, but methodologies for sensitively monitoring response to treatment are currently lacking. In this case series, we retrospectively examined the serial computed tomography (CT) findings in nine cats that had been diagnosed with tuberculosis. Changes in pathology (where applicable to tuberculosis) were correlated with the clinical presentation of each of the cats, the treatment protocol, and previous and contemporary diagnostic investigations. This study found that changes in CT findings during the medium- to long-term management of feline tuberculosis were highly variable between cats. The majority of cats had reduced pathology at re-examination during anti-tuberculous therapy, but pathology only resolved in a minority of cases. In some cases recurrence of pathology detected by CT imaging preceded clinical deterioration, allowing for rapid therapeutic intervention. Relevance and novel information: When considered in combination with clinical findings, CT studies can aid in decision making regarding tapering of antibiotic protocols, or reintroduction of therapy in cases of recurrence or reinfection. This series also highlights that, in some cases, persistent abnormalities can be detected by CT, so complete resolution of CT pathology should not always be a goal in the management of feline tuberculosis

    Humoral gut mucosal immune responses in the German shepherd dog

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    Available from British Library Document Supply Centre- DSC:DXN061055 / BLDSC - British Library Document Supply CentreSIGLEGBUnited Kingdo

    Is digital upskilling the next generation our ‘pipeline to prosperity’?

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    The British government is claiming digital skills will deliver economic growth to the country and social mobility to young people: its ministers call it ‘a pipeline to prosperity’. While declaring this pipeline, the government assumes the needs of the economy and young people’s needs are (or should be) synchronised. We challenge this assumption and the policy it sustains with data from questionnaires, workshops and interviews with 50 young people from communities in South Wales (including a former mining town and a deprived inner city area) about digital technology’s role in their everyday life. We use a new typography to compare the reality of their socially and economically structured lives to the governmental policy discourse that makes them responsible for their country’s future economic success. To explain these young people’s creative and transgressive use of technology, we also make an empirically grounded contribution to the ongoing theoretical debates about structure and agency.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This research was funded by the European Union – TRANSLITERACY project 645238/Horizon 2020–Research and Innovation action
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