21 research outputs found
Junín Virus Infection of Human Hematopoietic Progenitors Impairs In Vitro Proplatelet Formation and Platelet Release via a Bystander Effect Involving Type I IFN Signaling
- Author
- A Balduini
- A Basu
- A Sanchez
- A Yamane
- Agustín E. Ure
- AK Field
- AM Marty
- B Vainrub
- Barbara Sherry
- BL Jacobs
- C Ponzinibbio
- Carolina Jaquenod de Giusti
- CB Dejean
- CJ Peters
- CJ Peters
- D Binder
- D Cummins
- D Cummins
- D Gibellini
- DE Green
- F Norol
- F Villinger
- G Carballal
- H Isomura
- IB Sundell
- J Bekisz
- JL Cole
- Joseph E. Italiano
- JP Chen
- K Crapnell
- KS Broomhall
- LH Harrison
- Lina P. D'Atri
- M Bray
- M Iannacone
- Mirta Schattner
- MK Larson
- ML Flanagan
- MV Heller
- NA Candurra
- Oscar Torres
- P Bossi
- PA Lang
- PD Ghiringhelli
- PH Gonzalez
- Q Wang
- R Drillien
- RA Shivdasani
- RG Pozner
- Ricardo M. Gómez
- RM Gómez
- Roberto G. Pozner
- S Negrotto
- SC Levis
- SE Goni
- SR Patel
- SR Radoshitzky
- T Kawai
- TS Dhanjal
- TW Geisbert
- Victor Romanowski
- Y Chang
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2010
- Field of study
Argentine hemorrhagic fever (AHF) is an endemo-epidemic disease caused by Junín virus (JUNV), a member of the arenaviridae family. Although a recently introduced live attenuated vaccine has proven to be effective, AHF remains a potentially lethal infection. Like in other viral hemorrhagic fevers (VHF), AHF patients present with fever and hemorrhagic complications. Although the causes of the bleeding are poorly understood, impaired hemostasis, endothelial cell dysfunction and low platelet counts have been described. Thrombocytopenia is a common feature in VHF syndromes, and it is a major sign for its diagnosis. However, the underlying pathogenic mechanism has not yet been elucidated. We hypothesized that thrombocytopenia results from a viral-triggered alteration of the megakaryo/thrombopoiesis process. Therefore, we evaluated the impact of JUNV on megakaryopoiesis using an in vitro model of human CD34+ cells stimulated with thrombopoietin. Our results showed that CD34+ cells are infected with JUNV in a restricted fashion. Infection was transferrin receptor 1 (TfR1)-dependent and the surface expression of TfR1 was higher in infected cultures, suggesting a novel arenaviral dissemination strategy in hematopoietic progenitor cells. Although proliferation, survival, and commitment in JUNV-infected cultures were normal, viral infection impaired thrombopoiesis by decreasing in vitro proplatelet formation, platelet release, and P-selectin externalization via a bystander effect. The decrease in platelet release was also TfR1-dependent, mimicked by poly(I:C), and type I interferon (IFN α/β) was implicated as a key paracrine mediator. Among the relevant molecules studied, only the transcription factor NF-E2 showed a moderate decrease in expression in megakaryocytes from either infected cultures or after type I IFN treatment. Moreover, type I IFN-treated megakaryocytes presented ultrastructural abnormalities resembling the reported thrombocytopenic NF-E2−/− mouse phenotype. Our study introduces a potential mechanism for thrombocytopenia in VHF and other diseases associated with increased bone marrow type I IFN levels
Global burden of 369 diseases and injuries in 204 countries and territories, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
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- Adebayo OM
- Adedeji IA
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- Adelson JD
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- Nansseu JR
- Nasab EM
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- Nayak VC
- Nazari J
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- Ndwandwe DE
- Negoi I
- Negoi RI
- Netsere HB
- Neupane S
- Ngari KN
- Nguefack-Tsague G
- Ngunjiri JW
- Nguyen CT
- Nguyen DN
- Nguyen HLT
- Nguyen J
- Nguyen M
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- Nguyen TH
- Nichols E
- Nigatu D
- Nigatu YT
- Nikbakhsh R
- Nikpoor AR
- Nixon MR
- Nnaji CA
- Nomura S
- Norheim OF
- Norrving B
- Noubiap JJ
- Nowak C
- Nsoesie EO
- Nunez-Samudio V
- Oancea B
- Odell CM
- Ogbo FA
- Oghenetega OB
- Oh I-H
- Oiu AO
- Okunga EW
- Oladnabi M
- Olagunju AT
- Olusanya BO
- Olusanya JO
- Oluwasanu MM
- Omer MO
- Ong KL
- Ong S
- Onwujekwe OE
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- Orji AU
- Orpana HM
- Ortega-Altamirano DV
- Ortiz A
- Osarenotor O
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- Ranabhat CL
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- Skou ST
- Skryabin VY
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- Smith EUR
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- Soofi M
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- Sudaryanto A
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- Troeger CE
- Truelsen TC
- Tsai AC
- Tsatsakis A
- Tyrovolas S
- Uddin R
- Ullah I
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- Umeokonkwo CD
- Undurraga EA
- Unnikrishnan B
- Upadhyay E
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- Vakilian A
- Valdez PR
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- Veisani Y
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- Venketasubramanian N
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- Wickramasinghe ND
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- Woldu G
- Wolfe CDA
- Wondmeneh TG
- Wondmieneh AB
- Wool EE
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- Wu A-M
- Wu C
- Wu J
- Wunrow HY
- Xie Y
- Xu G
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- Yamada T
- Yamagishi K
- Yaminfirooz M
- Yano Y
- Yaya S
- Yazdi-Feyzabadi V
- Yearwood JA
- Yeheyis TY
- Yeshitila YG
- Yilgwan CS
- Yilma MT
- Yip P
- Yonemoto N
- Yoon S-J
- York HW
- Younis MZ
- Younker TP
- Yousefi B
- Yousefi Z
- Yousefifard M
- Yousefinezhadi T
- Yousuf AY
- Yu C
- Yu Y
- Yuan C-W
- Yuce D
- Yusefzadeh H
- Zadey S
- Zahabi SS
- Zaidi SS
- Zaki L
- Zaki MES
- Zakzuk J
- Zamani M
- Zamanian M
- Zandian H
- Zangeneh A
- Zarafshan H
- Zastrozhin MS
- Zewdie KA
- Zhang J
- Zhang Y
- Zhang Z-J
- Zhao JT
- Zhao X-JG
- Zhao Y
- Zheleva B
- Zheng P
- Zhou M
- Zhu C
- Ziapour A
- Zimsen SRM
- Zlavog BS
- Zodpey S
- Publication venue
- 'Elsevier BV'
- Publication date
- 17/10/2020
- Field of study
Five insights from the Global Burden of Disease Study 2019
- Author
- Abbafati C
- Abbas KM
- Abbasi M
- Abbasi-Kangevari M
- Abbasifard M
- Abbastabar H
- Abd El Razek HM
- Abd El Razek MM
- Abd-Allah F
- Abdelalim A
- Abdollahi M
- Abdollahpour I
- Abdulkader RS
- Abdullah KH
- Abedi A
- Abedi P
- Abegaz KH
- Abolhassani H
- Abosetugn AE
- Aboyans V
- Abrams EM
- Abreu LG
- Abrigo MRM
- Abu Haimed AK
- Abu-Gharbieh E
- Abu-Raddad LJ
- Abualhasan A
- Abushouk AI
- Acebedo A
- Ackerman IN
- Adabi M
- Adair T
- Adamu AA
- Adebayo OM
- Adedeji IA
- Adekanmbi V
- Adelson JD
- Adeoye AM
- Adetokunboh OO
- Adham D
- Advani SM
- Afarideh M
- Afshari M
- Afshin A
- Agardh EE
- Agarwal G
- Agasthi P
- Agesa KM
- Aghaali M
- Aghamir SMK
- Agrawal A
- Ahmad T
- Ahmadi A
- Ahmadi K
- Ahmadi M
- Ahmadieh H
- Ahmadpour E
- Ahmed MB
- Aji B
- Akalu TY
- Akinyemi RO
- Akinyemiju T
- Akombi B
- Akunna CJ
- Al-Aly Z
- Al-Mekhlafi HM
- Al-Raddadi RM
- Alahdab F
- Alam K
- Alam N
- Alam S
- Alam T
- Alanezi FM
- Alanzi TM
- Albertson SB
- Alcalde-Rabanal JE
- Alema NM
- Alemu BW
- Alemu YM
- Alhabib KF
- Alhassan RK
- Ali M
- Ali S
- Alicandro G
- Alijanzadeh M
- Alinia C
- Alipour V
- Alizade H
- Aljunid SM
- Alla F
- Allebeck P
- Almadi MAH
- Almasi A
- Almasi-Hashiani A
- Almasri NA
- Almulhim AM
- Alonso J
- Altirkawi KA
- Alumran AK
- Alvis-Guzman N
- Alvis-Zakzuk NJ
- Amare AT
- Amare B
- Amini S
- Amini-Rarani M
- Aminorroaya A
- Amiri F
- Amit AML
- Amugsi DA
- Amul GGH
- Anbesu EW
- Ancuceanu R
- Anderlini D
- Anderson JA
- Andrei CL
- Andrei T
- Androudi S
- Angus C
- Anjomshoa M
- Ansari F
- Ansari I
- Ansari-Moghaddam A
- Antonazzo IC
- Antonio CAT
- Antony CM
- Antriyandarti E
- Anvari D
- Anwer R
- Appiah SCY
- Arab-Zozani M
- Arabloo J
- Aravkin AY
- Arba AAK
- Aremu O
- Ariani F
- Aripov T
- Armoon B
- Arnlov J
- Arowosegbe OO
- Aryal KK
- Arzani A
- Asaad M
- Asadi-Aliabadi M
- Asadi-Pooya AA
- Asgari S
- Asghari B
- Ashbaugh C
- Assmus M
- Atafar Z
- Athari SS
- Atnafu DD
- Atout MMW
- Atre SR
- Atteraya MS
- Ausloos F
- Ausloos M
- Avila-Burgos L
- Avokpaho EFGA
- Ayano G
- Ayanore MA
- Aynalem GL
- Aynalem YA
- Ayza MA
- Azari S
- Azarian G
- Azene ZN
- Azhar G
- Azzopardi PS
- Babaee E
- Badawi A
- Badiye AD
- Bagherzadeh M
- Bagli E
- Bahrami MA
- Baig AA
- Bairwa M
- Bakhshaei MH
- Bakhtiari A
- Bakkannavar SM
- Balachandran A
- Balakrishnan S
- Balalla S
- Balassyano S
- Baldasseroni A
- Bali AO
- Ball K
- Ballew SH
- Balzi D
- Banach M
- Bandpei MAM
- Banerjee SK
- Banik PC
- Bannick MS
- Bante AB
- Bante SA
- Baraki AG
- Barboza MA
- Barker-Collo SL
- Barnighausen TW
- Barrero LH
- Barthelemy CM
- Barua L
- Barzegar A
- Basaleem H
- Bassat Q
- Basu S
- Baune BT
- Bayati M
- Baye BA
- Bazmandegan G
- Becker JS
- Bedi N
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- Bejot Y
- Bekuma TTT
- Bell ML
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- Bensenor IM
- Benziger CP
- Berhe K
- Berman AE
- Bernabe E
- Bernstein RS
- Bertolacci GJ
- Bhagavathula AS
- Bhageerathy R
- Bhala N
- Bhandari D
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- Bhat AG
- Bhattacharyya K
- Bhattarai S
- Bhutta ZA
- Bibi S
- Bicer BK
- Biehl MH
- Bijani A
- Bikbov B
- Bilano V
- Bin Sayeed MS
- Bin Zaman S
- Biondi A
- Birihane BM
- Bisanzio D
- Bisignano C
- Biswas RK
- Bitew H
- Bjorge T
- Bockarie MJ
- Bohlouli S
- Bohluli M
- Bojia HA
- Bolla SR
- Boloor A
- Boon-Dooley AS
- Borges G
- Borzi AM
- Borzouei S
- Bose D
- Bosetti C
- Boston S
- Boufous S
- Bourne R
- Brady OJ
- Braithwaite D
- Brauer M
- Brayne C
- Breitborde NJK
- Breitner S
- Brenner H
- Breusov AV
- Briant PS
- Briggs AM
- Briko AN
- Briko NI
- Britton GB
- Brugha T
- Bryazka D
- Buchbinder R
- Bumgarner BR
- Burkart K
- Burnett RT
- Busse R
- Butt ZA
- Caetano dos Santos FL
- Cahill LE
- Cahuana-Hurtado L
- Cai T
- Callender CSKH
- Camera LA
- Campos-Nonato IR
- Cao J
- Car J
- Car LT
- Cardenas R
- Carreras G
- Carrero JJ
- Carvalho F
- Castaldelli-Maia JM
- Castaneda-Orjuela CA
- Castelpietra G
- Castle CD
- Castro E
- Castro F
- Catala-Lopez F
- Causey K
- Cederroth CR
- Cercy KM
- Cerin E
- Chalek J
- Chandan JS
- Chang AR
- Chang AY
- Chang J-C
- Chang K-L
- Charan J
- Charlson FJ
- Chattu VK
- Chaturvedi S
- Cherbuin N
- Chimed-Ochir O
- Chin KL
- Chirinos-Caceres JL
- Cho DY
- Choi J-YJ
- Christensen H
- Chu D-T
- Chung MT
- Chung S-C
- Cicuttini FM
- Ciobanu LG
- Cirillo M
- Cislaghi B
- Classen TKD
- Cohen AJ
- Collins EL
- Comfort H
- Compton K
- Conti S
- Cooper OR
- Corso B
- Cortesi PA
- Costa VM
- Cousin E
- Cowden RG
- Cowie BC
- Cromwell EA
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- Cross DH
- Cross M
- Crowe CS
- Cruz JA
- Cummins S
- Cunningham M
- D'Amico E
- da Silva DD
- Dahlawi SMA
- Dai H
- Dai H
- Damasceno AAM
- Damiani G
- Dandona L
- Dandona R
- Daneshpajouhnejad P
- Dangel WJ
- Danielsson A-K
- Dargan PI
- Darshan BB
- Darwesh AM
- Daryani A
- Das Gupta R
- Das Neves J
- Das JK
- Dash AP
- Davey G
- Davila-Cervantes CA
- Davis AC
- Davitoiu DV
- Davletov K
- De Leo D
- De Neve J-W
- Dean FE
- DeCleene NK
- Deen A
- Defo BK
- Degenhardt L
- DeLang M
- Dellavalle RP
- Demeke FM
- Demoz GT
- Demsie DG
- Denova-Gutierrez E
- Dereje ND
- Deribe K
- Dervenis N
- Desai R
- Desalew A
- Dessie GA
- Deuba K
- Dharmaratne SD
- Dhungana GP
- Dianatinasab M
- Diaz D
- Dichgans M
- Didarloo A
- Dingels ZV
- Dippenaar IN
- Dirac MA
- Djalalinia S
- Do HT
- Dokova K
- Doku DT
- Dolecek C
- Dolgert AJ
- Dorostkar F
- Doshi CP
- Doshi PP
- Doshmangir L
- Douiri A
- Doxey MC
- Doyle KE
- Driscoll TR
- Dubljanin E
- Dunachie SJ
- Duncan BB
- Duraes AR
- Eagan AW
- Ebrahimi H
- Edvardsson D
- Effiong A
- Ehrlich JR
- El Nahas N
- El Sayed I
- El Tantawi M
- El-Jaafary SI
- Elbarazi I
- Elgendy IY
- Elhabashy HR
- Elsharkawy A
- Elyazar IRF
- Emamian MH
- Emmons-Bell S
- Erskine HE
- Eshrati B
- Eskandari K
- Eskandarieh S
- Esmaeilnejad S
- Esmaeilzadeh F
- Esteghamati A
- Esteghamati S
- Estep K
- Etemadi A
- Etisso AE
- Ezekannagha O
- Fanzo J
- Farag T
- Farahmand M
- Faraj A
- Faraon EJA
- Fareed M
- Faridnia R
- Farinha CSES
- Farioli A
- Faris PS
- Faro A
- Faruque M
- Farzadfar F
- Fattahi N
- Fazaeli AA
- Fazlzadeh M
- Feigin VL
- Feldman R
- Fereshtehnejad S-M
- Fernandes E
- Ferrara G
- Ferrara P
- Ferrari AJ
- Ferreira ML
- Feyissa GT
- Filip I
- Fischer F
- Fisher JL
- Fitzgerald R
- Flohr C
- Flor LS
- Foigt NA
- Folayan MO
- Fomenkov AA
- Force LM
- Fornari C
- Forooshani ZSD
- Foroutan M
- Fox JT
- Francis JM
- Frank TD
- Franklin RC
- Freitas M
- Fu W
- Fukumoto T
- Fukutaki K
- Fuller JE
- Fullman N
- Furtado JM
- Gad MM
- Gaidhane AM
- Gakidou E
- Galles NC
- Gallus S
- Gamkrelidze A
- Garcia-Basteiro AL
- Gardner WM
- Geberemariyam BS
- Gebrehiwot AM
- Gebremedhin KB
- Gebremeskel GG
- Gebremeskel LG
- Gebresillassie BM
- Gebreslassie AAAA
- Gela JD
- Geramo YCD
- Geremew A
- Gesesew HA
- Gething PW
- Gezae KE
- Ghadimi M
- Ghadiri K
- Ghaffarifar F
- Ghafourifard M
- Ghajar A
- Ghamari F
- Ghashghaee A
- Ghiasvand H
- Ghith N
- Gholamian A
- Ghosh R
- Giampaoli S
- Gilani SA
- Gill PS
- Gill TK
- Gillum RF
- Ginawi IA
- Ginindza TG
- Gitimoghaddam M
- Giussani G
- Glagn M
- Glushkova EV
- Gnedovskaya EV
- Godinho MA
- Goharinezhad S
- Golechha M
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- Gopalani SV
- Goren E
- Gorini G
- Gorman TM
- Gottlich HC
- Goudarzi H
- Goudarzian AH
- Goulart AC
- Goulart BNG
- Grada A
- Greaves F
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- Grosso G
- Gubari MIM
- Gudi N
- Gugnani HC
- Guimaraes ALS
- Guimaraes RA
- Guled RA
- Gultie T
- Guo G
- Guo Y
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- Gupta T
- Haagsma JA
- Hachinski V
- Haddock B
- Hafezi-Nejad N
- Hafiz A
- Hagins H
- Haile LM
- Haile TG
- Haj-Mirzaian A
- Haj-Mirzaian A
- Hall BJ
- Halvaei I
- Hamadeh RR
- Hameed S
- Hamidi S
- Hamilton EB
- Hammer MS
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- Han H
- Handiso DW
- Hanif A
- Hankey GJ
- Hanson SW
- Haririan H
- Haro JM
- Harvey JD
- Hasaballah AI
- Hasan MM
- Hasanpoor E
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- Publication venue
- Publication date
- 01/01/2020
- Field of study
The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.Peer reviewe
Multi-item Measurement of Subjective Wellbeing: Subjective Approaches (2)
- Author
- A Aubeeluck
- A Campbell
- A Dazord
- A Dazord
- A Dazord
- A Wahl
- AC Michalos
- AC Michalos
- AF Lehman
- AF Lehman
- AJ Tomyn
- AK Wahl
- AK Wahl
- AM Boonstra
- AR Fugl-Meyer
- AR Fugl-Meyer
- AS Waterman
- AS Waterman
- B Bowins
- B Headey
- BL Neugarten
- C Burckhardt
- C O’Cleirigh
- CA Lunney
- CC Riddick
- CE Ferrans
- CE Ferrans
- CE Ferrans
- CH Wu
- CH Wu
- CH Wu
- CJ Best
- CR Leana
- CS Burckhardt
- CS Burckhardt
- CS Burckhardt
- CS Carver
- D Heider
- D Renn
- DH Olson
- DL Adams
- DR Hoyt
- E Diener
- E Diener
- E Langeland
- E Wills
- EA Locke
- EA Locke
- FM Andrews
- FM Andrews
- G Henrich
- GJ Treharne
- GJ Treharne
- I Daig
- I McDowell
- J Brown
- J Hall
- J Liang
- J Oliver
- J Vitterso
- JA Faris
- JA Russell
- JA Russell
- JC Flanagan
- JC Flanagan
- JD Blore
- JG Lang
- JM Arzouman
- K Bruscia
- KM Bennett
- KS Rook
- L Goldbeck
- L Kulik
- L Perry
- LCH Lai
- M Davern
- M Rosenberg
- M Viitanen
- M Wooden
- MB Frisch
- MB Frisch
- MB Frisch
- MB Frisch
- MD Thomas
- MD Thomas
- MG Evans
- MJ Sirgy
- MJ Sirgy
- MP Lawton
- MR Hagerty
- MWM Post
- N Claiborne
- N Schwarz
- N Schwarz
- NM McAlinden
- NS Rocha da
- O Leelakulthanit
- P Costa
- P Gerin
- P Huxley
- P Man
- P Warr
- P Warr
- PE Meehl
- PL Zhang
- PR Clifford
- PS Mikes
- R Rato
- RA Cummins
- RA Cummins
- RA Cummins
- RA Cummins
- RA Cummins
- RA Cummins
- RA Cummins
- RA Cummins
- RA Greene
- RD Caplan
- RM Renwick
- RM Ryan
- S Priebe
- S Schmidt
- SD Gosling
- SI Woodruff
- SI Woodruff
- SL Bourland
- T Rustoen
- T Trauer
- VWQ Lou
- W Eng
- WA Stock
- WHOQOL Group
- WHOQOL Group
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2014
- Field of study
Functional Voltage-Gated Sodium Channels Are Expressed in Human Intestinal Epithelial Cells
- Author
- Akopian AN
- Alon Lang
- Bjorck S
- Black JA
- Boiko T
- Breese EJ
- Burgess DL
- Catterall WA
- Catterall WA
- Catterall WA
- Cummins TR
- Cummins TR
- Daig R
- DeCoursey TE
- Diebel LN
- Diss JK
- Ella Fudim
- Fraser SP
- Holm AN
- Inagaki A
- Iris Barshack
- Jo T
- Jung HC
- Lahav M
- Levite M
- Li RA
- Marban E
- Mia Levite
- Orit Picard
- Planells-Cases R
- Ragsdale DS
- Rando TA
- Shomron Ben Horin
- Uhlig HH
- Wittmack EK
- Yehuda Chowers
- Yu FH
- Publication venue
- 'S. Karger AG'
- Publication date
- 01/01/2008
- Field of study
Multidimensional construct of life satisfaction in older adults in Korea: a six-year follow-up study
- Author
- A Efklides
- A Shankar
- A Stone
- AI Berg
- AI Berg
- AL Collins
- BM Baird
- C Borg
- C Chen
- C Li
- C Rocke
- C Victor
- Chel Hee Lee
- D Gerstorf
- D Gerstorf
- DA Regier
- Dae Kee Min
- DG Blanchflower
- DK Mroczek
- E Diener
- E Hamarat
- F Fujita
- F Subasi
- FD Ferring
- FR Lang
- H Huang
- H Kimm
- H Kooshiar
- H Millward
- HK Linda
- Hyun Ja Lim
- J An
- J Gaymu
- J Singer
- J Smith
- JD Grann
- JM Murphy
- JW Rowe
- K Gana
- K Yamaoka
- KL Chou
- KM Bennett
- KM Everard
- Lilian Thorpe
- M Janke
- M Pinquart
- M Pinquart
- M Silverstein
- ME Lacruz
- NL Chappell
- NS Park
- P Banjare
- R Mojtabai
- RA Cummins
- RA Lang Cummins
- RAR Gurung
- RK Horst Van Der
- S Carmel
- S Humboldt von
- S Humboldt Von
- SB Pattern
- SG Lee
- SN Jang
- ST Cheng
- T Oshio
- United Nations
- W Gwozdz
- W Pan
- W Zhang
- WJ Katon
- Y Al-Kandari
- Y Zhou
- Z Zimmer
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Review Article. Cardiac troponins and renal disease
- Author
- Adams JE
- Adams JE
- Anderson PA
- Apple FS
- Apple FS
- Apple FS
- Bertinchant JP
- Bhayana V
- Bleier J
- Bodor GS
- Bodor GS
- Chapelle JP
- Collinson PO
- Collinson PO
- Cummins P
- Dean KJ
- Del Carlo CH
- Dierkes J
- Ellis K
- Escalon JC
- Ferjani M
- Godon P
- Hafner G
- Hamm CW
- Hunkeler NM
- Jaffe AS
- Joint European Society of Cardiology/American College of Cardiology Committee.
- Katrukha AG
- Katus HA
- Khan IA
- Kollef MH
- Labugger R
- Lang K
- Mair J
- Mair J
- McLaurin MD
- McNeil AR
- Missov E
- Nakamura S
- Ooi DS
- Ooi DS
- Parmacek MS
- Pearlstone JR
- Porter GA
- Ravkilde J
- Ricchiutti V
- Robbins MJ
- Sato Y
- Spies C
- Wayand D
- Wolfe RA
- Wu AH
- Wu AH
- Wu AH
- Wu AH
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Carbon dioxide-sensing in organisms and its implications for human disease
- Author
- A Bretscher
- A Goel
- A Kaplan
- A Missner
- AD Nichol
- AF Broccard
- AM Allen
- AM Li
- Andrew C. Selfridge
- ARDSnet
- B Yang
- BH Abuaita
- C Bongiorni
- C Gehring
- C Hachez
- CJ Lang
- Cormac T. Taylor
- CT Taylor
- CT Taylor
- D Dreyfuss
- D Kadosh
- D O’Toole
- DD Sin
- DF O’Croinin
- DF O’Croinin
- DL Granger
- E Hallem
- E Hallem
- E Laserna
- E Nattie
- E Soupene
- EA Hallem
- EG Mogensen
- Eoin P. Cummins
- EP Cummins
- G Blain
- G Huang
- G Stange
- G Suh
- GF Curley
- GF Curley
- GL Semenza
- H Du
- H Forster
- HM Robertson
- I Vadász
- IC Solomon
- IT Helenius
- J Buck
- J Chandrashekar
- J Chen
- J Haldane
- J Hu
- J López-Barneo
- J Roelofs
- J Young
- JA Hyde
- JA Skinner
- Jacob I. Sznajder
- JB Dean
- JG Laffey
- JG Laffey
- JR Beitler
- JR Beitler
- K Sharabi
- K Takeshita
- KD Passalacqua
- KH Groenewegen
- KM Moser
- KM Oliver
- L Sun
- L Welch
- M Abolhassani
- M Aggarwal
- M Gohar
- M Kamenetsky
- M Ni Chonghaile
- M Suver
- MA West
- MB Amato
- ML Guillermin
- MN Chonghaile
- MS Hayden
- N Ramanantsoa
- N Uehlein
- N Wang
- NL Nakhoul
- O Zaragoza
- P Munday
- P Townsend
- PA Wright
- Peter H. Sporn
- R Huckstepp
- R Monastersky
- R Musa-Aziz
- RA Belkin
- RA Hall
- RD Gilmore Jr
- RT Huckstepp
- S Elleuche
- S Kustu
- S Lindskog
- S Lindskog
- S Perry
- S Ravi
- S Turner
- S Xue
- SE Hester
- SE Sinclair
- SF Perry
- SN Greer
- T Dekker
- T Klengel
- T Poulos
- T Shimamura
- T-H Kim
- TC Corbridge
- TR Martin
- U Feller
- W Boron
- WB Frommer
- WD Jones
- WG Kaelin Jr
- XG Wang
- Y Chen
- YS Bahn
- YS Bahn
- Z Cook
- Z Qin
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 30/04/2014
- Field of study
The capacity of organisms to sense changes in the levels of internal and external gases and to respond accordingly is central to a range of physiologic and pathophysiologic processes. Carbon dioxide, a primary product of oxidative metabolism is one such gas that can be sensed by both prokaryotic and eukaryotic cells and in response to altered levels, elicit the activation of multiple adaptive pathways. The outcomes of activating CO2-sensitive pathways in various species include increased virulence of fungal and bacterial pathogens, prey-seeking behavior in insects as well as taste perception, lung function, and the control of immunity in mammals. In this review, we discuss what is known about the mechanisms underpinning CO2 sensing across a range of species and consider the implications of this for physiology, disease progression, and the possibility of developing new therapeutics for inflammatory and infectious disease.Deposited by bulk impor
Chemical plaque control ? prevention for the masses
- Author
- Abbott DM
- Adey RH.
- Afflitto J
- Albandar JM
- Ash M
- Ayad F
- Bakdash B.
- Balanyk TE.
- Banoczy J
- Barkvoll P.
- Bhatti SA
- Boyd RL
- Briner WW
- Butler JA.
- Ciancio SG
- Ciancio SG.
- Claydon N
- Cubells AB
- Cummins D.
- Deasy MJ
- Denton GW.
- Finkelstein P
- Fleming TF
- Foot RL
- Francis JR
- Frandsen A.
- Gazi M
- Gilbert RJ
- Gilbert RJ.
- Gjermo P
- Gjermo P.
- Helgeland K
- Kopczyk RA
- Kornman KS.
- Lamster IB
- Lang NP
- Llewelyn J.
- Loe H
- Loe H
- Loesche WJ
- Mallett ME
- Mandel ID.
- Mankodi S
- Marechal M.
- Mashimo PA
- Mauriello SM
- Moghadam BK
- Moran J
- Moustafa MH
- Nabi N
- Newman M.
- Nilzen A
- Page RC
- Palcanis KG
- Palomo F
- Pucher JJ
- Rosa MR
- Rose G.
- Ross NM
- Saxen L
- Saxer U
- Saxton CA
- Schiott CR
- Syed SA
- Toors FA.
- Volpe AR
- Yankell SL
- Yeung S
- Yusof WZ
- Publication venue
- 'Wiley'
- Publication date
- Field of study
Metal Complexes Featuring Photochromic Ligands
- Author
- A Beyeler
- A Fernandez-Acebes
- A Fernandez-Acebes
- A Moriuchi
- A Natansohn
- A Sakamoto
- AJ Myles
- AK Chisibov
- AN Nesmeyanov
- AN Nesmeyanov
- B Qin
- B Qin
- CC Ko
- CC Ko
- D Sud
- DS Tyson
- E Murguly
- FM Raymo
- FM Raymo
- G Guirado
- GS Kumar
- H Dürr
- H Konada
- H Lang
- H Nishihara
- H Tian
- H Tian
- HD Samachetty
- HJ Kim
- HS Tang
- J Han
- J Han
- J Luc
- J Luc
- JA Delaire
- JKW Lee
- JL Bahr
- JTC Wojtyk
- K Kinbara
- K Kume
- K Kume
- K Matsuda
- K Matsuda
- K Takayama
- K Uchida
- K Yamaguchi
- L Viau
- L Viau
- M Giraud
- M Irie
- M Irie
- M Kurihara
- M Kurihara
- M Kurihara
- M Munakata
- M Munakata
- M Nihei
- M Querol
- MT Indelli
- O Maury
- P Belser
- P Belser
- P Brun
- PHM Lee
- RA Kopelman
- RF Khairutdinov
- RH Mitchell
- RH Mitchell
- RH Mitchell
- RH Mitchell
- RTF Jukes
- RTF Jukes
- RTF Jukes
- S Anguille
- S Anguille
- S Bidault
- S Kawata
- S Muratsugu
- S Nagashima
- S Xiao
- SD Cummins
- SL Gilat
- T Muraoka
- T Muraoka
- T Nakagawa
- T Nakagawa
- T Yutaka
- T Yutaka
- T Yutaka
- T Yutaka
- T Yutaka
- TA Golovka
- V Aubert
- V Ferri
- VI Minkin
- VWW Yam
- VWW Yam
- W Fan
- YW Zhong
- Z Bao
- Z Zhou
- Z Zhou
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2010
- Field of study