X-ray narrow line region variability as a geometry probe: The case of NGC 5548

We study the long time scale variability of the gas responsible for the X-ray narrow emission lines in the Seyfert 1 galaxy NGC 5548, in order to constrain the location and geometry of the emitting gas. Using X-ray spectra taken with the Chandra-LETGS and HETGS instruments and with XMM-Newton RGS and combining them with long-term monitoring observations of the Rossi X-ray Timing Explorer (RXTE), we perform a correlation analysis in order to try constrain the time scale on which the narrow line emitting gas responds to variations of the continuum flux. With the inclusion of the 2007 Chandra-LETGS observation we have an additional observation at an historically low flux level. We conclude that the NLR in NGC 5548 is in the form of an ionization cone, compact in size, and located between 1 and 15 pc from the central source, depending on the exact geometry of the NLR.Comment: 6 pages, 4 figures, accepted for publication in A&

The outflow in Mrk 509: A method to calibrate XMM-Newton EPIC-pn and RGS

We have analyzed three XMM-Newton observations of the Seyfert 1 galaxy Mrk 509, with the goal to detect small variations in the ionized outflow properties. Such measurements are limited by the quality of the cross-calibration between RGS, the best instrument to characterize the spectrum, and EPIC-pn, the best instrument to characterize the variability. For all three observations we are able to improve the relative calibration of RGS and pn consistently to 4 %. In all observations we detect three different outflow components and, thanks to our accurate cross-calibration we are able to detect small differences in the ionization parameter and column density in the highest ionized component of the outflow. This constrains the location of this component of the outflow to within 0.5 pc of the central source. Our method for modeling the relative effective area is not restricted to just this source and can in principle be extended to other types of sources as well.Comment: 11 pages, 9 figure

Light elements in massive single and binary stars

We highlight the role of the light elements (Li, Be, B) in the evolution of massive single and binary stars, which is largely restricted to a diagnostic value, and foremost so for the element boron. However, we show that the boron surface abundance in massive early type stars contains key information about their foregoing evolution which is not obtainable otherwise. In particular, it allows to constrain internal mixing processes and potential previous mass transfer event for binary stars (even if the companion has disappeared). It may also help solving the mystery of the slowly rotating nitrogen-rich massive main sequence stars.Comment: 10 pages, 8 figures, to appear in proc. IAU-Symp. 268. C. Charbonnel et al., eds

Multiwavelength campaign on Mrk 509. V. Chandra-LETGS observation of the ionized absorber

We present here the results of a 180 ks Chandra-LETGS observation as part of a large multi-wavelength campaign on Mrk 509. We study the warm absorber in Mrk 509 and use the data from a simultaneous HST-COS observation in order to assess whether the gas responsible for the UV and X-ray absorption are the same. We analyzed the LETGS X-ray spectrum of Mrk 509 using the SPEX fitting package. We detect several absorption features originating in the ionized absorber of the source, along with resolved emission lines and radiative recombination continua. The absorption features belong to ions with, at least, three distinct ionization degrees. The lowest ionized component is slightly redshifted (v = +73 km/s) and is not in pressure equilibrium with the others, and therefore it is not likely part of the outflow, possibly belonging to the interstellar medium of the host galaxy. The other components are outflowing at velocities of -196 and -455 km/s, respectively. The source was observed simultaneously with HST-COS, finding 13 UV kinematic components. At least three of them can be kinematically associated with the observed X-ray components. Based on the HST-COS results and a previous FUSE observation, we find evidence that the UV absorbing gas might be co-located with the X-ray absorbing gas and belong to the same structure.Comment: 12 pages, 7 figures, 9 tables. Accepted for publication in Astronomy & Astrophysic

The warm absorber in NGC 5548: The lean years

We study the variability of the warm absorber and the gas responsible for the emission lines in the Seyfert 1 galaxy NGC 5548, in order to constrain the location and physical properties of these components. Using X-ray spectra taken with the \textit{Chandra}$-$LETGS in 2002 and 2005, we study variability in the ionic column densities and line intensities. We find a lower \ion{O}{vii} forbidden emission line flux in 2005, while the Fe K$\alpha$ line flux stays constant. The warm absorber is less ionized in 2005, allowing us to constrain its location to within 7 pc of the central source. Using both the observed variability and the limit on the FWHM of the \ion{O}{vii} f line, we have constrained the location of the narrow line region to a distance of 1 pc from the central source. The apparent lack of variability of the Fe K$\alpha$ line flux does not allow for a unique explanation.Comment: 6 pages, 6 figures, accepted by A&

Gamma-Ray Bursts from tidally spun-up Wolf-Rayet stars?

The collapsar model requires rapidly rotating Wolf-Rayet stars as progenitors of long gamma-ray bursts. However, Galactic Wolf-Rayet stars rapidly lose angular momentum due to their intense stellar winds. We investigate whether the tidal interaction of a Wolf-Rayet star with a compact object in a binary system can spin up the Wolf-Rayet star enough to produce a collapsar. We compute the evolution of close Wolf-Rayet binaries, including tidal angular momentum exchange, differential rotation of the Wolf-Rayet star, internal magnetic fields, stellar wind mass loss, and mass transfer. The Wolf-Rayet companion is approximated as a point mass. We then employ a population synthesis code to infer the occurrence rates of the various relevant binary evolution channels. We find that the simple scenario -- i.e., the Wolf-Rayet star being tidally spun up and producing a collapsar -- does not occur at solar metallicity and may only occur with low probability at low metallicity. It is limited by the widening of the binary orbit induced by the strong Wolf-Rayet wind or by the radius evolution of the Wolf-Rayet star that most often leads to a binary merger. The tidal effects enhance the merger rate of Wolf-Rayet stars with black holes such that it becomes comparable to the occurrence rate of long gamma-ray bursts.Comment: 9 pages, 11 figures, accepted for publication in A&

A phenomenological model for the X-ray spectrum of Nova V2491 Cygni

The X-ray flux of Nova V2491 Cyg reached a maximum some forty days after optical maximum. The X-ray spectrum at that time, obtained with the RGS of XMM-Newton, shows deep, blue-shifted absorption by ions of a wide range of ionization. We show that the deep absorption lines of the X-ray spectrum at maximum, and nine days later, are well described by the following phenomenological model with emission from a central blackbody and from a collisionally ionized plasma (CIE). The blackbody spectrum (BB) is absorbed by three main highly-ionized expanding shells; the CIE and BB are absorbed by cold circumstellar and interstellar matter that includes dust. The outflow density does not decrease monotonically with distance. The abundances of the shells indicate that they were ejected from an O-Ne white dwarf. We show that the variations on time scales of hours in the X-ray spectrum are caused by a combination of variation in the central source and in the column density of the ionized shells. Our phenomenological model gives the best description so far of the supersoft X-ray spectrum of nova V2491 Cyg, but underpredicts, by a large factor, the optical and ultraviolet flux. The X-ray part of the spectrum must originate from a very different layer in the expanding envelope, presumably much closer to the white dwarf than the layers responsible for the optical/ultraviolet spectrum. This is confirmed by absence of any correlation between the X-ray and UV/optical observed fluxes.Comment: 11 pages, 6 figure

Опухоли с невыявленным первичным очагом: современные подходы к лечению

Представлены современные методы и схемы лечения разных видов рака с невыясненным очагом и получаемые результаты.Contemporary methods of treatment of various types of cancer with unrevealed focus as well as the obtained results are described

Isolation of a novel aquaglyceroporin from a marine teleost (Sparus auratus) Function and tissue distribution

The aquaporins (formerly called the major intrinsic protein family) are transmembrane channel proteins. The family includes the CHIP group, which are functionally characterised as water channels and the GLP group, which are specialised for glycerol transport. The present study reports the identification and characterisation of a novel GLP family member in a teleost fish, the sea bream Sparus auratus. A sea bream aquaporin (sbAQP) cDNA of 1047·bp and encoding a protein of 298·amino acids was isolated from a kidney cDNA library. Functional characterization of the sbAQP using a Xenopus oocyte assay revealed that the isolated cDNA stimulated osmotic water permeability in a mercury-sensitive manner and also stimulated urea and glycerol uptake. Northern blotting demonstrated that sbAQP was expressed at high levels in the posterior region of the gut, where two transcripts were identified (1.6·kb and 2·kb), and in kidney, where a single transcript was present (2·kb). In situ hybridisation studies with a sbAQP riboprobe revealed its presence in the lamina propria and smooth muscle layer of the posterior region of the gut and in epithelial cells of some kidney tubules. sbAQP was also present in putative chloride cells of the gill. Phylogenetic analysis of sbAQP, including putative GLP genes from Fugu rubripes, revealed that it did not group with any of the previously isolated vertebrate GLPs and instead formed a separate group, suggesting that it may be a novel GLP member.This work was supported by project PRAXIS XXI/2/2.1/BIA/211/94 from the Portuguese National Science and Technology Foundation (FCT), co-financed by EU structural funds, DG-Fisheries Project Q5RS-2002-00784 (CRYOCYTE) and an EU Biotech grant (QLRT2000-00778). C.R.A.S., J.C.R.C. and J.F. were in receipt of FCT fellowships PRAXIS XXI/BPD/22040/99, PRAXIS XXI/BD/19925/99BPD/22033/99, respectively