Correlation functions in the factorization approach of nonextensive quantum statistics

We study the long range behavior of a gas whose partition function depends on a parameter q and it has been claimed to be a good approximation to the partition function proposed in the formulation of nonextensive statistical mechanics. We compare our results, at large temperatures and at the critical point, with the case of Boltzmann-Gibbs thermodynamics for the case of a Bose-Einstein gas. In particular, we find that for all temperatures the long range correlations in a Bose gas decrease when the value of q departs from the standard value q=1.Comment: revtex file, 10 pages, two eps style figures, packaged as a single tar.gz fil

A uniform procedure for the purification of CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1

We have established a uniform procedure for the expression and purification of the cyclin-dependent kinases CDK7/CycH/MAT1, CDK8/CycC and CDK9/CycT1. We attach a His(6)-tag to one of the subunits of each complex and then co-express it together with the other subunits in Spodoptera frugiperda insect cells. The CDK complexes are subsequently purified by Ni(2+)-NTA and Mono S chromatography. This approach generates large amounts of active recombinant kinases that are devoid of contaminating kinase activities. Importantly, the properties of these recombinant kinases are similar to their natural counterparts (Pinhero et al. 2004, Eur J Biochem 271:1004-14). Our protocol provides a novel systematic approach for the purification of these three (and possibly other) recombinant CDKs

Sensory Processing Sensitivity and its association with personality traits and affect: A meta-analysis

In two Bayesian meta-analyses, we investigated associations between Sensory Processing Sensitivity (SPS) and the Big Five personality traits (MA1) as well as both Positive and Negative Affect (MA2). Moderators were age and the three SPS subscales. In MA1 (8 papers, 6790 subjects), SPS in children correlated with Neuroticism (r\u202f=\u202f0.42) but did not with Extraversion, Openness, Agreeableness or Conscientiousness. In adults, SPS correlated with Openness (r\u202f=\u202f0.14) and Neuroticism (r\u202f=\u202f0.40) but did not with Extraversion, Agreeableness or Conscientiousness. In MA2 (19 papers, 5326 subjects), SPS in children correlated with Negative (r\u202f=\u202f0.29) and Positive Affect (r\u202f=\u202f0.21), but only with Negative Affect (r\u202f=\u202f0.34) in adults. Developmental and measurement aspects are discussed

Adhesion Forces and Coaggregation between Vaginal Staphylococci and Lactobacilli

Urogenital infections are the most common ailments afflicting women. They are treated with dated antimicrobials whose efficacy is diminishing. The process of infection involves pathogen adhesion and displacement of indigenous Lactobacillus crispatus and Lactobacillus jensenii. An alternative therapeutic approach to antimicrobial therapy is to reestablish lactobacilli in this microbiome through probiotic administration. We hypothesized that lactobacilli displaying strong adhesion forces with pathogens would facilitate coaggregation between the two strains, ultimately explaining the elimination of pathogens seen in vivo. Using atomic force microscopy, we found that adhesion forces between lactobacilli and three virulent toxic shock syndrome toxin 1-producing Staphylococcus aureus strains, were significantly stronger (2.2–6.4 nN) than between staphylococcal pairs (2.2–3.4 nN), especially for the probiotic Lactobacillus reuteri RC-14 (4.0–6.4 nN) after 120 s of bond-strengthening. Moreover, stronger adhesion forces resulted in significantly larger coaggregates. Adhesion between the bacteria occurred instantly upon contact and matured within one to two minutes, demonstrating the potential for rapid anti-pathogen effects using a probiotic. Coaggregation is one of the recognized mechanisms through which lactobacilli can exert their probiotic effects to create a hostile micro-environment around a pathogen. With antimicrobial options fading, it therewith becomes increasingly important to identify lactobacilli that bind strongly with pathogens

Perceived Surface Slant Is Systematically Biased in the Actively-Generated Optic Flow

Humans make systematic errors in the 3D interpretation of the optic flow in both passive and active vision. These systematic distortions can be predicted by a biologically-inspired model which disregards self-motion information resulting from head movements (Caudek, Fantoni, & Domini 2011). Here, we tested two predictions of this model: (1) A plane that is stationary in an earth-fixed reference frame will be perceived as changing its slant if the movement of the observer's head causes a variation of the optic flow; (2) a surface that rotates in an earth-fixed reference frame will be perceived to be stationary, if the surface rotation is appropriately yoked to the head movement so as to generate a variation of the surface slant but not of the optic flow. Both predictions were corroborated by two experiments in which observers judged the perceived slant of a random-dot planar surface during egomotion. We found qualitatively similar biases for monocular and binocular viewing of the simulated surfaces, although, in principle, the simultaneous presence of disparity and motion cues allows for a veridical recovery of surface slant