Fullerene van der waals Oligomers as electron traps

Density functional theory calculations indicate that van der Waals fullerene dimers and larger oligomers can form interstitial electron traps in which the electrons are even more strongly bound than in isolated fullerene radical anions. The fullerenes behave like super atoms , and the interstitial electron traps represent one-electron intermolecular σ-bonds. Spectroelectrochemical measurements on a bis-fullerene-substituted peptide provide experimental support. The proposed deep electron traps are relevant for all organic electronics applications in which non-covalently linked fullerenes in van der Waals contact with one another serve as n-type semiconductors

The Grizzly, November 7, 2019

Have you Heard the Rumors ? • Day of the Dead Celebration • Director Makes UC Debut with String Ensemble • Wellness Workshops Focus on Mindfulness • UrCinema Club Returns for Film Lovers • Opinion: Jesus is King, but Yeezus is Not • What is the Chain Gang ? • Women\u27s Basketball Ready for New Seasonhttps://digitalcommons.ursinus.edu/grizzlynews/1594/thumbnail.jp

The Grizzly, November 21, 2019

UC\u27s Fourth Annual Celebration of Lights • Berman Museum\u27s Fall Exhibitions • Missy Bryant Named New Dean of Students • 2020 Commencement Speaker Announced • Students Explore Philly in Philly Word • GSA Reflects on Semester\u27s Exciting Events • Opinions: NY Fare Evasion Laws Harm Marginalized Groups; Harriet is a Triumph of a Biopic • Opening Tourney is a Slam Dunk for Men\u27s Basketball • Freshman Wrestlers Headline Fall Brawlhttps://digitalcommons.ursinus.edu/grizzlynews/1596/thumbnail.jp

The impact and significance of tephra deposition on a Holocene forest environment in the North Cascades, Washington, USA.

© 2016 Elsevier Ltd. High-resolution palaeoecological analyses (stratigraphy, tephra geochemistry, radiocarbon dating, pollen and ordination) were used to reconstruct a Holocene vegetation history of a watershed in the Pacific Northwest of America to evaluate the effects and duration of tephra deposition on a forest environment and the significance of these effects compared to long-term trends. Three tephra deposits were detected and evaluated: MLF-T158 and MLC-T324 from the climactic eruption of Mount Mazama, MLC-T480 from a Late Pleistocene eruption of Mount Mazama and MLC-T485 from a Glacier Peak eruption. Records were examined from both the centre and fringe of the basin to elucidate regional and local effects. The significance of tephra impacts independent of underlying long-term trends was confirmed using partial redundancy analysis. Tephra deposition from the climactic eruption of Mount Mazama approximately 7600 cal. years BP caused a significant local impact, reflected in the fringe location by changes to open habitat vegetation (Cyperaceae and Poaceae) and changes in aquatic macrophytes (Myriophyllum spicatum, Potamogeton, Equisetum and the alga Pediastrum). There was no significant impact of the climactic Mazama tephra or other tephras detected on the pollen record of the central core. Changes in this core are potentially climate driven. Overall, significant tephra fall was demonstrated through high resolution analyses indicating a local effect on the terrestrial and aquatic environment, but there was no significant impact on the regional forest dependent of underlying environmental changes

M-House

exterio

Deep Drilling with the ANDRILL Program in Antarctica

ANDRILL (ANtarctic geological DRILLing) is a new international, multi-disciplinary drilling program that targets geological records that lie hidden beneath the icy blanket of Antarctica. The primary objective is to investigate Antarctica’s role in global environmental change over the past sixty-five million years, at various scales of age resolution, and thereby enhance our understanding of Antarctica’s potential response to future global changes. Efforts to understand the influence of Antarctica on global climate change require a fundamental knowledge of how the Antarctic cryosphere (ice sheets, ice shelves, and sea ice) has evolved, not only in recent times but also during earlier geological periods when global temperature and atmospheric CO2 levels were similar to what might be reached by the end of this century. ANDRILL’s integrated science approach will use stratigraphic drilling, coring, and multi-proxy core analysis combined with geophysical surveys and numerical modeling to study the Cenozoic history of Antarctic climate and ice sheets, the evolution of polar biota, Antarctic tectonism, and Antarctica’s role in the evolution of Earth’s ocean–climate system. The two inaugural ANDRILL projects, McMurdo Ice Shelf Project (MIS) and Southern McMurdo Sound Project (SMS), will be drilled in late 2006 and late 2007, respectively, in the McMurdo Sound Region of the Ross Sea (for science plans, see http://andrill.org), and research on these projects will continue throughout the International Polar Year (IPY, 2007–2008). Funding from Germany, Italy, New Zealand, and the United States supported the development of a new dedicated drilling system and drilling camp for ice-based operations. The anticipated twenty-year lifespan of the drilling rig is expected to enable future drilling in other regions of the Antarctic margin. Future ANDRILL projects will depend on new proposals to national funding agencies. ANDRILL is managed through the McMurdo-ANDRILL Science Implementation Committee (M-ASIC) and the ANDRILL Operations Management Group (AOMG), whose directions are implemented through the Science Management Office (SMO) at the University of Nebraska-Lincoln and the Project Operator’s Office within Antarctica New Zealand, respectively. Ongoing and future community involvement, proposal development, and site characterization are encouraged, facilitated, and coordinated by the ANDRILL Science Committee (ASC) and the SMO

Antarctic drilling recovers stratigraphic records from the continental margin

The Antarctic Geological Drilling (ANDRILL) program—a collaboration between Germany, Italy, New Zealand, and the United States that is one of the larger programs endorsed by the International Polar Year (IPY; http:// www .ipy .org)—successfully completed the drilling phase of the Southern McMurdo Sound (SMS) Project in December 2007. This second drill core of the program’s campaign in the western Ross Sea, Antarctica, complements the results of the first drilling season [Naish et al., 2007] by penetrating deeper into the stratigraphic section in the Victoria Land Basin and extending the recovered time interval back to approximately 20 million years ago. The primary objectives of ANDRILL (http:// www .andrill .org/) were to recover stratigraphic records from the Antarctic continental margin that document key steps in Antarctica’s Cenozoic (0- to 65-million- year- old) climatic and glacial history, and in the tectonic evolution of the Transantarctic Mountains and the West Antarctic Rift System [Harwood et al., 2006]. These two ANDRILL stratigraphic drill cores are guiding the understanding of the speed, size, and frequency of the past 20 million years of glacial and interglacial changes in the Antarctic region. The drill cores will help to establish, through their correlation to existing records and their integration with climate and ice sheet models, how these local changes relate to regional and global events

Oxidative degradation of bilirubin produces vasoactive compounds

Subarachnoid haemorrhage is often followed by haemolysis and concomitant oxidative stress, and is frequently complicated by pathological vasoconstriction or cerebral vasospasm. It is known that upregulation of haem oxygenase (HO-1) is induced by oxidative stress and results in release of biliverdin and bilirubin (BR), which are scavengers of reactive oxygen species (ROS). Here we report biomimetic studies aimed at modelling pathological conditions leading to oxidative degradation of BR. Oxidative degradation products of BR, formed by reaction with hydrogen peroxide (an ROS model system), demonstrated biological activity by stimulating oxygen consumption and force development in vascular smooth muscle from porcine carotid artery. Analogous biological activity was observed with vasoactive cerebrospinal fluid from subarachnoid haemorrhage patients. Three degradation products of BR were isolated: two were assigned as isomeric monopyrrole (C<sub>9</sub>H<sub>11</sub>N<sub>2</sub>O<sub>2</sub>) derivatives, 4-methyl-5-oxo-3-vinyl-(1,5-dihydropyrrol-2-ylidene)acetamide and 3-methyl-5-oxo-4-vinyl-(1,5-dihydropyrrol-2-ylidene)acetamide and the third was 4-methyl-3-vinylmaleimide (MVM), a previously isolated photodegradation product of biliverdin. Possible mechanisms of oxidative degradation of BR are discussed. Tentative assignment of these structures in the cerebrospinal fluid (CSF) of cerebral vasospasm patients has been made. It is proposed that one or more of the degradation products of biliverdin or bilirubin are involved in complications such as vasospasm and or pathological vasoconstriction associated with haemorrhage

International Olympic Committee (IOC) consensus statement on acute respiratory illness in athletes part 1: acute respiratory infections

International audienceAcute illnesses affecting the respiratory tract are common and form a significant component of the work of Sport and Exercise Medicine (SEM) clinicians. Acute respiratory illness (ARill) can broadly be classified as non-infective ARill and acute respiratory infections (ARinf). The aim of this consensus is to provide the SEM clinician with an overview and practical clinical approach to ARinf in athletes. The International Olympic Committee (IOC) Medical and Scientific Commission appointed an international consensus group to review ARill (non-infective ARill and ARinf) in athletes. Six subgroups of the IOC Consensus group were initially established to review the following key areas of ARill in athletes: (1) epidemiology/risk factors for ARill, (2) ARinf, (3) non-infective ARill including ARill due to environmental exposure, (4) acute asthma and related conditions, (5) effects of ARill on exercise/sports performance, medical complications/return-to-sport and (6) acute nasal/vocal cord dysfunction presenting as ARill. Several systematic and narrative reviews were conducted by IOC consensus subgroups, and these then formed the basis of sections in the consensus documents. Drafting and internal review of sections were allocated to ‘core’ members of the consensus group, and an advanced draft of the consensus document was discussed during a meeting of the main consensus core group in Lausanne, Switzerland on 11 to 12 October 2021. Final edits were completed after the meeting. This consensus document (part 1) focusses on ARinf, which accounts for the majority of ARill in athletes. The first section of this consensus proposes a set of definitions and classifications of ARinf in athletes to standardise future data collection and reporting. The remainder of the consensus paper examines a wide range of clinical considerations related to ARinf in athletes: epidemiology, risk factors, pathology/pathophysiology, clinical presentation and diagnosis, management, prevention, medical considerations, risks of infection during exercise, effects of infection on exercise/sports performance and return-to-sport guidelines