Descripción ambiental de la Laguna de Lobos, pcia. Bs.As. Una propuesta para su monitoreo

Periodic hydrologic and ecological alterations in the Lobos’s shallow lake in the last few years and concern and interest of intitutions and authorities, which both value the preservation of the place as a touristic, recreative and sportive resource, have motivated the implementation of the Program of permamanent surveillance of environmental quality of Lobos’s shallow lake . This programe includes low budget and of concrete implementation initiatives using local resources for evaluating the dynamic together with the shallow lake’s environmental quality and its main afluent, Las Garzas’s stream, in a continuous period of time. This study has been carreid out in a framework which has as a main objective to periodically analyze this shallow lake and its afluent’s most significant limnologic variables and to detect any system’s alteration caused by the conjuction of environmental and/or climatic unfavorable conditions or local or regional environmental impacts of diverse origins (industrial, from sewers, or from farming activity). Seventeen samplings have been developed from January of 2000 until September of 2008 in two different areas of study: First Area: Las Garzas Stream and drainage channels, with 4 stations of sampling next to industrial and cattle areas; Second Area: Lobos’s shallow lake, with 4 stations of sampling of hydrologic interest. In each stage of the sampling, the deep, turbidity, pH, temperature and dissolved oxygen was registered and samples of fytoplankton for its cualitative and quantitative analysis were taken. In the First Area, in March of 2001, February of 2004 and Spetember of 2008 samplings show that the unload of efluents have afected the quality of the water of Las Garzas’s stream. Limonologic characteristics of the Second Area show a close relation whit season variables and, in general, the water presented conditions that can be adapted to recreative use. The death of fishes occurred in March of 2000, January of 2001 and July of 2006 coincide with the low levels of oxygen dissolved in the water, high temperatures in relation with the avareage and the amount of algaes (more than 50000 cells/ml) dominated by cyanophytes. The analysis of hydrologic and biologic variables of this shallow lake and its afluent have allowed to achieve periodic observations of this hydric environment, know its dynamic and detect the causes of ecological alterations in the environment. Besides, it has provided with new tools to fund new decisions taken regarding to the managing of the shallow lake.Instituto de Limnología "Raúl A. Ringuelet

Descripción ambiental de la Laguna de Lobos, pcia. Bs.As. Una propuesta para su monitoreo

Periodic hydrologic and ecological alterations in the Lobos’s shallow lake in the last few years and concern and interest of intitutions and authorities, which both value the preservation of the place as a touristic, recreative and sportive resource, have motivated the implementation of the Program of permamanent surveillance of environmental quality of Lobos’s shallow lake . This programe includes low budget and of concrete implementation initiatives using local resources for evaluating the dynamic together with the shallow lake’s environmental quality and its main afluent, Las Garzas’s stream, in a continuous period of time. This study has been carreid out in a framework which has as a main objective to periodically analyze this shallow lake and its afluent’s most significant limnologic variables and to detect any system’s alteration caused by the conjuction of environmental and/or climatic unfavorable conditions or local or regional environmental impacts of diverse origins (industrial, from sewers, or from farming activity). Seventeen samplings have been developed from January of 2000 until September of 2008 in two different areas of study: First Area: Las Garzas Stream and drainage channels, with 4 stations of sampling next to industrial and cattle areas; Second Area: Lobos’s shallow lake, with 4 stations of sampling of hydrologic interest. In each stage of the sampling, the deep, turbidity, pH, temperature and dissolved oxygen was registered and samples of fytoplankton for its cualitative and quantitative analysis were taken. In the First Area, in March of 2001, February of 2004 and Spetember of 2008 samplings show that the unload of efluents have afected the quality of the water of Las Garzas’s stream. Limonologic characteristics of the Second Area show a close relation whit season variables and, in general, the water presented conditions that can be adapted to recreative use. The death of fishes occurred in March of 2000, January of 2001 and July of 2006 coincide with the low levels of oxygen dissolved in the water, high temperatures in relation with the avareage and the amount of algaes (more than 50000 cells/ml) dominated by cyanophytes. The analysis of hydrologic and biologic variables of this shallow lake and its afluent have allowed to achieve periodic observations of this hydric environment, know its dynamic and detect the causes of ecological alterations in the environment. Besides, it has provided with new tools to fund new decisions taken regarding to the managing of the shallow lake.Instituto de Limnología "Raúl A. Ringuelet

Descripción ambiental de la Laguna de Lobos, pcia. Bs.As. Una propuesta para su monitoreo

Periodic hydrologic and ecological alterations in the Lobos’s shallow lake in the last few years and concern and interest of intitutions and authorities, which both value the preservation of the place as a touristic, recreative and sportive resource, have motivated the implementation of the Program of permamanent surveillance of environmental quality of Lobos’s shallow lake . This programe includes low budget and of concrete implementation initiatives using local resources for evaluating the dynamic together with the shallow lake’s environmental quality and its main afluent, Las Garzas’s stream, in a continuous period of time. This study has been carreid out in a framework which has as a main objective to periodically analyze this shallow lake and its afluent’s most significant limnologic variables and to detect any system’s alteration caused by the conjuction of environmental and/or climatic unfavorable conditions or local or regional environmental impacts of diverse origins (industrial, from sewers, or from farming activity). Seventeen samplings have been developed from January of 2000 until September of 2008 in two different areas of study: First Area: Las Garzas Stream and drainage channels, with 4 stations of sampling next to industrial and cattle areas; Second Area: Lobos’s shallow lake, with 4 stations of sampling of hydrologic interest. In each stage of the sampling, the deep, turbidity, pH, temperature and dissolved oxygen was registered and samples of fytoplankton for its cualitative and quantitative analysis were taken. In the First Area, in March of 2001, February of 2004 and Spetember of 2008 samplings show that the unload of efluents have afected the quality of the water of Las Garzas’s stream. Limonologic characteristics of the Second Area show a close relation whit season variables and, in general, the water presented conditions that can be adapted to recreative use. The death of fishes occurred in March of 2000, January of 2001 and July of 2006 coincide with the low levels of oxygen dissolved in the water, high temperatures in relation with the avareage and the amount of algaes (more than 50000 cells/ml) dominated by cyanophytes. The analysis of hydrologic and biologic variables of this shallow lake and its afluent have allowed to achieve periodic observations of this hydric environment, know its dynamic and detect the causes of ecological alterations in the environment. Besides, it has provided with new tools to fund new decisions taken regarding to the managing of the shallow lake.Instituto de Limnología "Raúl A. Ringuelet

Descripción ambiental de la Laguna de Lobos, pcia. Bs.As

Periodic hydrologic and ecological alterations in the Lobos’s shallow lake in the last few years and concern and interest of intitutions and authorities, which both value the preservation of the place as a touristic, recreative and sportive resource, have motivated the implementation of the Program of permamanent surveillance of environmental quality of Lobos’s shallow lake . This programe includes low budget and of concrete implementation initiatives using local resources for evaluating the dynamic together with the shallow lake’s environmental quality and its main afluent, Las Garzas’s stream, in a continuous period of time. This study has been carreid out in a framework which has as a main objective to periodically analyze this shallow lake and its afluent’s most significant limnologic variables and to detect any system’s alteration caused by the conjuction of environmental and/or climatic unfavorable conditions or local or regional environmental impacts of diverse origins (industrial, from sewers, or from farming activity). Seventeen samplings have been developed from January of 2000 until September of 2008 in two different areas of study: First Area: Las Garzas Stream and drainage channels, with 4 stations of sampling next to industrial and cattle areas; Second Area: Lobos’s shallow lake, with 4 stations of sampling of hydrologic interest. In each stage of the sampling, the deep, turbidity, pH, temperature and dissolved oxygen was registered and samples of fytoplankton for its cualitative and quantitative analysis were taken. In the First Area, in March of 2001, February of 2004 and Spetember of 2008 samplings show that the unload of efluents have afected the quality of the water of Las Garzas’s stream. Limonologic characteristics of the Second Area show a close relation whit season variables and, in general, the water presented conditions that can be adapted to recreative use. The death of fishes occurred in March of 2000, January of 2001 and July of 2006 coincide with the low levels of oxygen dissolved in the water, high temperatures in relation with the avareage and the amount of algaes (more than 50000 cells/ml) dominated by cyanophytes. The analysis of hydrologic and biologic variables of this shallow lake and its afluent have allowed to achieve periodic observations of this hydric environment, know its dynamic and detect the causes of ecological alterations in the environment. Besides, it has provided with new tools to fund new decisions taken regarding to the managing of the shallow lake.Periodic hydrologic and ecological alterations in the Lobos’s shallow lake in the last few years and concern and interest of intitutions and authorities, which both value the preservation of the place as a touristic, recreative and sportive resource, have motivated the implementation of the Program of permamanent surveillance of environmental quality of Lobos’s shallow lake. This programe includes low budget and of concrete implementation initiatives using local resources for evaluating the dynamic together with the shallow lake’s environmental quality and its main afluent, Las Garzas’s stream, in a continuous period of time. This study has been carreid out in a framework which has as a main objective to periodically analyze this shallow lake and its afluent’s most significant limnologic variables and to detect any system’s alteration caused by the conjuction of environmental and/or climatic unfavorable conditions or local or regional environmental impacts of diverse origins (industrial, from sewers, or from farming activity). Seventeen samplings have been developed from January of 2000 until September of 2008 in two different areas of study: First Area: Las Garzas Stream and drainage channels, with 4 stations of sampling next to industrial and cattle areas; Second Area: Lobos’s shallow lake, with 4 stations of sampling of hydrologic interest. In each stage of the sampling, the deep, turbidity, pH, temperature and dissolved oxygen was registered and samples of fytoplankton for its cualitative and quantitative analysis were taken. In the First Area, in March of 2001, February of 2004 and Spetember of 2008 samplings show that the unload of efluents have afected the quality of the water of Las Garzas’s stream. Limonologic characteristics of the Second Area show a close relation whit season variables and, in general, the water presented conditions that can be adapted to recreative use. The death of fishes occurred in March of 2000, January of 2001 and July of 2006 coincide with the low levels of oxygen dissolved in the water, high temperatures in relation with the avareage and the amount of algaes (more than 50000 cells/ml) dominated by cyanophytes. The analysis of hydrologic and biologic variables of this shallow lake and its afluent have allowed to achieve periodic observations of this hydric environment, know its dynamic and detect the causes of ecological alterations in the environment. Besides, it has provided with new tools to fund new decisions taken regarding to the managing of the shallow lake

Evidence of sexuality in induced tetraploids of Brachiaria brizantha (Poaceae).

Made available in DSpace on 2018-05-31T00:36:58Z (GMT). No. of bitstreams: 1 ID262371.pdf: 517213 bytes, checksum: 2243f8787a54feb71a540022fff8de45 (MD5) Previous issue date: 2005-12-1

Mortality attributable to COVID-19 in nursing home residents: a retrospective study

Aim: Coronavirus-19 disease (COVID-19) is a widespread condition in nursing home (NH). It is not known whether COVID-19 is associated with a higher risk of death than residents without COVID-19. Therefore, the aim of this study was to assess whether COVID-19 is associated with a higher mortality rate in NH residents, considering frailty status assessed with the Multidimensional Prognostic Index (MPI). Methods: In this retrospective study, made in 31 NHs in Venice, Italy, the presence of COVID-19 was ascertained with a nasopharyngeal swab. Frailty was evaluated using the MPI, modified according to the tools commonly used in our NHs. A Cox’s regression analysis was used reporting the results as hazard ratios (HRs) with 95% confidence intervals (CIs), using COVID-19 as exposure and mortality as outcome and stratified by MPI tertiles. Similar analyses were run using MPI tertiles as exposure. Results: Overall, 3946 NH residents (median age = 87 years, females: 73.9%) were eligible, with 1136 COVID-19 +. During a median follow-up of 275 days, higher values of MPI, indicating frailer people, were associated with an increased risk of mortality. The incidence of mortality in COVID-19 + was more than doubled than COVID-19- either in MPI-1, MPI-2 and MPI-3 groups. The presence of COVID-19 increased the risk of death (HR = 1.85; 95% CI 1.59–2.15), also in the propensity score model using MPI as confounder (HR = 2.48; 95% CI 2.10–2.93). Conclusion: In this retrospective study of NH residents, COVID-19 was associated with a higher risk of all-cause mortality than those not affected by COVID-19 also considering the different grades of frailty. © 2021, The Author(s)

k cl co transport plays an important role in normal and β thalassemic erythropoiesis

Background and Objectives Cell volume changes are hallmarks of both cell maturation and apoptosis, and are paralleled by modulation of membrane ion transport pathways. We evaluated the possible role of K-Cl co-transport (KCC) in both normal and β-thalassemic erythropoiesis in vitro . Design and Methods We studied the effects of the KCC inhibitor, DIOA, on cell proliferation and differentiation, on expression of KCC mRNA and polypeptides, and on expression of cell cycle and apoptosis genes in in vitro liquid-cultures of CD34+ cells from normal and β-thalassemic subjects. Results β-thalassemic erythroid precursors showed increased abundance of KCC1-3 mRNA and of KCC polypeptides in late erythropoiesis. DIOA markedly modified the composition of normal erythroid precursors, promoting differentiation and arrest at the polychromatic erythroblast stage and resulting in a precursor distribution profile similar to that of untreated β-thalassemic cells. DIOA up-regulated cyclin-D mRNA levels in late erythropoiesis in both cell models, paralleling changes in the percentage of S-phase-cells. Caspase-3 activity in late erythropoiesis declined to similar degrees in both cell models. DIOA did not modify caspase-3 or -8 mRNA levels. Interpretation and Conclusions Ineffective erythropoiesis of in vitro cultured β-thalassemic cells is likely related to impaired cell maturation. KCC activity appears to contribute to erythroid cell growth during late erythropoiesis

Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis

: Recent studies have shown that the tumor extracellular matrix (ECM) associates with immunosuppression, and that targeting the ECM can improve immune infiltration and responsiveness to immunotherapy. A question that remains unresolved is whether the ECM directly educates the immune phenotypes seen in tumors. Here, we identify a tumor-associated macrophage (TAM) population associated with poor prognosis, interruption of the cancer immunity cycle, and tumor ECM composition. To investigate whether the ECM was capable of generating this TAM phenotype, we developed a decellularized tissue model that retains the native ECM architecture and composition. Macrophages cultured on decellularized ovarian metastasis shared transcriptional profiles with the TAMs found in human tissue. ECM-educated macrophages have a tissue-remodeling and immunoregulatory phenotype, inducing altered T cell marker expression and proliferation. We conclude that the tumor ECM directly educates this macrophage population found in cancer tissues. Therefore, current and emerging cancer therapies that target the tumor ECM may be tailored to improve macrophage phenotype and their downstream regulation of immunity

Combined Therapy with Insulin and Growth Hormone in 17 Patients with Type-1 Diabetes and Growth Disorders.

Combined growth hormone (GH) and insulin therapy is rarely prescribed by pediatric endocrinologists. We investigated the attitude of Italian physicians to prescribing that therapy in the case of short stature and type-1 diabetes (T1DM). Methods: A questionnaire was sent and if a patient was identified, data on growth and diabetes management were collected. Results: Data from 42 centers (84%) were obtained. Of these, 29 centers reported that the use of combined therapy was usually avoided. A total of 17 patients were treated in 13 centers (GH was started before T1DM onset in 9 patients and after the onset of T1DM in 8). Height SDS patterns during GH therapy in the 11 patients affected by GH deficiency ranged from -0.3 to +3.1 SDS. In the 8 diabetic patients in whom GH was added subsequently, mean insulin dose increased during the first 6 months of therapy from 0.7 ± 0.2 to 1.0 ± 0.2 U/kg (p = 0.004). HbA1c was unchanged during the first 6 months of combined therapy. Conclusions: Most Italian physicians do not consider prescribing the combined GH-insulin therapy in diabetic children with growth problems. However, the results of the 17 patients identified would confirm that the combined therapy was feasible and only caused mild insulin resistance. GH therapy was effective in promoting growth in most patients and did not affect diabetes metabolic contro

Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE