106 research outputs found

    China Cues for Smart Shoppers

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    China tableware of good quality is perhaps one of the most prized possessions a homemaker can have. And selecting a life~time pattern often confronts the college woman planning for marriage or career

    The Homemaker is Yours

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    Home economics students as a group are unaware of many of the services and activities of the Homemaker. 1962 is a big year for your magazine! This is the 40th Anniversary year of its publication

    Knees are News

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    Knees are news this fall as fashion\u27s fickle hemline rises to dizzy heights. The shorter skirts not only barely skim the kneecap but in casual sportswear even creep above it

    The Iowa Homemaker vol.40, no.3

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    The Green Will Fade, Mary Ellen Muckenhirn, page 4 Being Your Best, Madeline Lange, page 5 New Faces in Home Economics, Beth Beecher, page 6 Touchdown or Touchback?, Sylvia Noid, page 8 Knees are News, Barbara Strang, Doris Post, page 8 Beauty Prescription, Marjean Swann, page 11 What’s Going On?, Patty Anderson, page 1

    The Iowa Homemaker vol.40, no.2

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    Let Art Speak, page 3 Dean LeBaron’s Travel Folio of Asia, Diane Houser, page 4 Iowa State, Husband-Hunting Grounds, Sylvia Noid, page 6 Two Ways to See Europe, Doris Post and Patty Anderson, page 7 Coffee House on the Left Bank, Beth Lambeth, page 8 Drip-Dry Through Europe, Myra Scholten, page 10 Memo to Suitcase Stuffers, Mary Ellen Muckenhirn, page 12 What’s Going On?, Carol Shellenbarger, page 1

    The Iowa Homemaker vol.40, no.1

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    As Others See Us, Tom Emmerson, Beth Lambeth and Sue Guernsey, page 6 China Cues for Smart Shoppers, Doris Post, page 8 Reflections of You, Sylvia Noid, page 9 Campus Tours, Inc., Patty Anderson, page 10 Child Development Experts Study “Multiple Mother” Effects, Carol Calhoon, page 11 Behind the TV Camera, Carolynn DeLay, page 12 Gray Meals, One Subject of Food Technology, Mary Ellen Muckenhirn, page 14 Coed Chooses Spring Fashion’s Fancy, Laveda Jansonius, page 17 Expand Your World, Marty Keeney, page 18 RAIN, Diane Houser, page 21 What’s Going On?, Carol Shellenbarger, page 2

    Common genetic variants improve risk stratification after the atrial switch operation for transposition of the great arteries

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    Background: Clinical factors are used to estimate late complication risk in adults after atrial switch operation (AtrSO) for transposition of the great arteries (TGA), but heterogeneity in clinical course remains. We studied whether common genetic variants are associated with outcome and add value to a clinical risk score in TGA-AtrSO patients. Methods and results: This multicenter study followed 133 TGA-AtrSO patients (aged 28 [IQR 24–35] years) for 13 (IQR 9–16) years and examined the association of genome-wide single-nucleotide polymorphisms (SNPs) with a composite endpoint of symptomatic ventricular arrhythmia, heart failure hospitalization, ventricular assist device implantation, heart transplantation, or mortality. Thirty-two patients (24%) reached the endpoint. The genome-wide association study yielded one genome-wide significant (p 20%) risk. Stratified by the combined score, observed 5-year event-free survival was 100%, 79% and 31% for low, intermediate, and high-risk patients, respectively. Conclusions: Common genetic variants may explain some variation in the clinical course in TGA-AtrSO and improve risk stratification over clinical factors alone, especially in patients at intermediate clinical risk. These findings support the hypothesis that including genetic variants in risk assessment may be beneficial

    On the notion of home and the goals of palliative care

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    The notion of home is well known from our everyday experience, and plays a crucial role in all kinds of narratives about human life, but is hardly ever systematically dealt with in the philosophy of medicine and health care. This paper is based upon the intuitively positive connotation of the term “home.” By metaphorically describing the goal of palliative care as “the patient’s coming home,” it wants to contribute to a medical humanities approach of medicine. It is argued that this metaphor can enrich our understanding of the goals of palliative care and its proper objectives. Four interpretations of “home” and “coming home” are explored: (1) one’s own house or homelike environment, (2) one’s own body, (3) the psychosocial environment, and (4) the spiritual dimension, in particular, the origin of human existence. Thinking in terms of coming home implies a normative point of view. It represents central human values and refers not only to the medical-technical and care aspects of health care, but also to the moral context

    Exogenous Ether Lipids Predominantly Target Mitochondria

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    Ether lipids are ubiquitous constituents of cellular membranes with no discrete cell biological function assigned yet. Using fluorescent polyene-ether lipids we analyzed their intracellular distribution in living cells by microscopy. Mitochondria and the endoplasmic reticulum accumulated high amounts of ether-phosphatidylcholine and ether-phosphatidylethanolamine. Both lipids were specifically labeled using the corresponding lyso-ether lipids, which we established as supreme precursors for lipid tagging. Polyfosine, a fluorescent analogue of the anti-neoplastic ether lipid edelfosine, accumulated to mitochondria and induced morphological changes and cellular apoptosis. These data indicate that edelfosine could exert its pro-apoptotic power by targeting and damaging mitochondria and thereby inducing cellular apoptosis. In general, this study implies an important role of mitochondria in ether lipid metabolism and intracellular ether lipid trafficking
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