2,268 research outputs found
Concepts and concreteness in psycholinguistics
This thesis is about the concrete-abstract distinction (âconcretenessâ) as it applies in psycholinguistic research and theories of concepts. Concreteness is one of the most-investigated psycholinguistic variables, and is also the basis for major disputes about the nature of the human conceptual system. However, I argue that concreteness is not actually a useful construct, and that the units of the conceptual system do not neatly match up with words of natural language, as is often assumed in the experimental and theoretical literatures. I dispute evidence for âconcreteness effectsâ, whereby words with high concreteness ratings exhibit processing differences relative to words with low concreteness ratings. The concreteness measure itself has statistical properties that invalidate it as a psycholinguistic tool. I report four new experiments designed to take into account these troublesome statistical properties, and maximise the chances of finding a concreteness effect. Counterintuitively, in three out of four experiments, the effect disappeared, and in the fourth it was extremely small. I suggest that evidence for concreteness effects is not as strong as it appears to be. Furthermore, even if the effects are real, current explanations of them still fail in various ways. I also consider how the concrete-abstract distinction intersects with popular theories of concepts and cognition, with an emphasis on two in particular (a Fodorian Language of Thought, and a Barsalou-ian Simulator theory). Using the alleged âabstractâ concept JUSTICE as an example, I argue that from the point of view of these theories, some abstract concepts are explanatorily vacuous: they do not actually offer any insight into behaviour or cognition. I conclude that although many âconcreteâ items belong in our theories of concepts, some alleged âabstractâ concepts arenât concepts at all. I explore some positive implications of this conclusion for theories of word meaning, and for theories of concepts in general
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Enrollment of adolescents and young adults onto SWOG cancer research network clinical trials: A comparative analysis by treatment site and era.
BackgroundFew adolescents and young adults (AYAs, 15-39 years old) enroll onto cancer clinical trials, which hinders research otherwise having the potential to improve outcomes in this unique population. Prior studies have reported that AYAs are more likely to receive cancer care in community settings. The National Cancer Institute (NCI) has led efforts to increase trial enrollment through its network of NCI-designated cancer centers (NCICC) combined with community outreach through its Community Clinical Oncology Program (CCOP; replaced by the NCI Community Oncology Research Program in 2014).MethodsUsing AYA proportional enrollment (the proportion of total enrollments who were AYAs) as the primary outcome, we examined enrollment of AYAs onto SWOG therapeutic trials at NCICC, CCOP, and non-NCICC/non-CCOP sites from 2004 to 2013 by type of site, study period (2004-08 vs 2009-13), and patient demographics.ResultsOverall, AYA proportional enrollment was 10.1%. AYA proportional enrollment decreased between 2004-2008 and 2009-2013 (13.1% vs 8.5%, P < .001), and was higher at NCICCs than at CCOPs and non-NCICC/non-CCOPs (14.1% vs 8.3% and 9.2%, respectively; P < .001). AYA proportional enrollment declined significantly at all three site types. Proportional enrollment of AYAs who were Black or Hispanic was significantly higher at NCICCs compared with CCOPs or non-NCICC/non-CCOPs (11.5% vs 8.8, P = .048 and 11.5% vs 8.6%, P = .03, respectively).ConclusionNot only did community sites enroll a lower proportion of AYAs onto cancer clinical trials, but AYA enrollment decreased in all study settings. Initiatives aimed at increasing AYA enrollment, particularly in the community setting with attention to minority status, are needed
Is there a reliability challenge for logic?
There are many domains about which we think we are reliable. When there is prima facie reason to believe that there is no satisfying explanation of our reliability about a domain given our background views about the world, this generates a challenge to our reliability about the domain or to our background views. This is what is often called the reliability challenge for the domain. In previous work, I discussed the reliability challenges for logic and for deductive inference. I argued for four main claims: First, there are reliability challenges for logic and for deduction. Second, these reliability challenges cannot be answered merely by providing an explanation of how it is that we have the logical beliefs and employ the deductive rules that we do. Third, we can explain our reliability about logic by appealing to our reliability about deduction. Fourth, there is a good prospect for providing an evolutionary explanation of the reliability of our deductive reasoning. In recent years, a number of arguments have appeared in the literature that can be applied against one or more of these four theses. In this paper, I respond to some of these arguments. In particular, I discuss arguments by Paul Horwich, Jack Woods, Dan Baras, Justin Clarke-Doane, and Hartry Field
ICP polishing of silicon for high quality optical resonators on a chip
Miniature concave hollows, made by wet etching silicon through a circular
mask, can be used as mirror substrates for building optical micro-cavities on a
chip. In this paper we investigate how ICP polishing improves both shape and
roughness of the mirror substrates. We characterise the evolution of the
surfaces during the ICP polishing using white-light optical profilometry and
atomic force microscopy. A surface roughness of 1 nm is reached, which reduces
to 0.5 nm after coating with a high reflectivity dielectric. With such smooth
mirrors, the optical cavity finesse is now limited by the shape of the
underlying mirror
The Uses of Argument in Mathematics
Stephen Toulmin once observed that `it has never been customary for
philosophers to pay much attention to the rhetoric of mathematical debate'.
Might the application of Toulmin's layout of arguments to mathematics remedy
this oversight?
Toulmin's critics fault the layout as requiring so much abstraction as to
permit incompatible reconstructions. Mathematical proofs may indeed be
represented by fundamentally distinct layouts. However, cases of genuine
conflict characteristically reflect an underlying disagreement about the nature
of the proof in question.Comment: 10 pages, 5 figures. To be presented at the Ontario Society for the
Study of Argumentation Conference, McMaster University, May 2005 and LOGICA
2005, Hejnice, Czech Republic, June 200
Counteridenticals
A counteridentical is a counterfactual with an identity statement in the antecedent. While counteridenticals generally seem non-trivial, most semantic theories for counterfactuals, when combined with the necessity of identity and distinctness, attribute vacuous truth conditions to such counterfactuals. In light of this, one could try to save the orthodox theories either by appealing to pragmatics or by denying that the antecedents of alleged counteridenticals really contain identity claims. Or one could reject the orthodox theory of counterfactuals in favor of a hyperintensional semantics that accommodates non-trivial counterpossibles. In this paper, I argue that none of these approaches can account for all the peculiar features of counteridenticals. Instead, I propose a modified version of Lewisâs counterpart theory, which rejects the necessity of identity, and show that it can explain all the peculiar features of counteridenticals in a satisfactory way. I conclude by defending the plausibility of contingent identity from objections
Serum 25-Hydroxyvitamin D and Intact Parathyroid Hormone Influence Muscle Outcomes in Children and Adolescents
Increases in 25-hydroxyvitamin D concentrations are shown to improve strength in adults; however, data in pediatric populations are scant and equivocal. In this ancillary study of a larger-scale, multi-sited, double-blind, randomized, placebo-controlled vitamin D intervention in US children and adolescents, we examined the associations between changes in vitamin D metabolites and changes in muscle mass, strength, and composition after 12 weeks of vitamin D3 supplementation. Healthy male and female, black and white children and adolescents between the ages of 9 and 13 years from two US states (Georgia 34°N and Indiana 40°N) were enrolled in the study and randomly assigned to receive an oral vitamin D3 dose of 0, 400, 1000, 2000, or 4000âIU/d for 12 weeks between the winter months of 2009 to 2011 (Nâ=â324). Analyses of covariance, partial correlations, and regression analyses of baseline and 12-week changes (post-baseline) in vitamin D metabolites (serum 25(OH)D, 1,25(OH)2 D, intact parathyroid hormone [iPTH]), and outcomes of muscle mass, strength, and composition (total body fat-free soft tissue [FFST], handgrip strength, forearm and calf muscle cross-sectional area [MCSA], muscle density, and intermuscular adipose tissue [IMAT]) were assessed. Serum 25(OH)D and 1,25(OH)2 D, but not iPTH, increased over time, as did fat mass, FFST, forearm and calf MCSA, forearm IMAT, and handgrip strength (pâ<â0.05). Vitamin D metabolites were not associated with muscle strength at baseline nor after the 12-week intervention. Changes in serum 25(OH)D correlated with decreases in forearm IMAT, whereas changes in serum iPTH predicted increases in forearm and calf MCSA and IMAT (pâ<â0.05). Overall, increases in 25(OH)D did not influence muscle mass or strength in vitamin D-sufficient children and adolescents; however, the role of iPTH on muscle composition in this population is unknown and warrants further investigation
Groundwater study of the Pingrup townsite
A groundwater study was carried out in the townsite of Pingrup. It aimed to accelerate the implementation of effective salinity risk management. The study consisted of a drilling investigation and expansion of a piezometer network, a pumping test, groundwater flow modelling and a flood risk analysis
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