56 research outputs found
Quatre aspects de lâappropriation des relations formation-emploi ?
Notre objectif est ici de rendre compte dâune relecture personnelle et donc « coupable », constituant une sorte de postface spontanĂ©e, assortie dâun questionnement rĂ©sultant dâun problĂšme qui est apparu Ă la maniĂšre dâun fil courant dâun texte Ă lâautre, sans intention prĂ©alable des auteurs des quatre articles qui prĂ©cĂšdent ni a fortiori commande de la rĂ©daction. Ce fil directeur renvoie au concept dâappropriation des connaissances sur les relations formation-emploi et plus prĂ©cisĂ©ment Ă une..
PrĂ©sentation de lâouvrage « Sâorienter dans la vie : une valeur suprĂȘme ? Dictionnaire de sciences humaines »
Les publications qui traitent de lâorientation scolaire et/ou professionnelle peuvent ĂȘtre classĂ©es en trois catĂ©gories. Il y a dâabord les guides Ă finalitĂ© documentaire sur les formations et/ou les mĂ©tiers. Ce premier type pouvant par ailleurs sâadresser aux praticiens de lâaccueil, de lâinformation et de lâorientation (AIO) ou aux diffĂ©rents publics dâusagers. On trouve ensuite les productions destinĂ©es exclusivement aux professionnels de lâAIO et relevant de leur formation initiale et con..
Introduction : Sous lâapparence dâune conversion « écologique » gĂ©nĂ©rale, des Ă©volutions dâampleur et dâintensitĂ© contrastĂ©es
LâĂ©mergence croissante de la prise en compte des prĂ©occupations Ă©cologiques induit des mutations socio-Ă©conomiques profondes. Elle affecte le champ de la formation et de nombreux secteurs dâemploi dont les pĂ©rimĂštres et les contenus se trouvent ĂȘtre questionnĂ©s, voire reconfigurĂ©s. La question Ă©cologique se dĂ©cline en des termes comme la « protection de lâenvironnement » et celle « de la nature », la « pollution », les « économies dâĂ©nergie », la « croissance verte », la « dĂ©croissance », la..
Low-frequency variation near common germline susceptibility loci are associated with risk of Ewing sarcoma
Background: Ewing sarcoma (EwS) is a rare, aggressive solid tumor of childhood, adolescence and young adulthood associated with pathognomonic EWSR1-ETS fusion oncoproteins altering transcriptional regulation. Genome-wide association studies (GWAS) have identified 6 common germline susceptibility loci but have not investigated low-frequency inherited variants with minor allele frequencies below 5% due to limited genotyped cases of this rare tumor. Methods We investigated the contribution of rare and low-frequency variation to EwS susceptibility in the largest EwS genome-wide association study to date (733 EwS cases and 1,346 unaffected controls of European ancestry). Results We identified two low-frequency variants, rs112837127 and rs2296730, on chromosome 20 that were associated with EwS risk (OR = 0.186 and 2.038, respectively;P-value < 5x10(-8)) and located near previously reported common susceptibility loci. After adjusting for the most associated common variant at the locus, only rs112837127 remained a statistically significant independent signal (OR = 0.200, P-value = 5.84x10(-8)). Conclusions: These findings suggest rare variation residing on common haplotypes are important contributors to EwS risk. Impact Motivate future targeted sequencing studies for a comprehensive evaluation of low-frequency and rare variation around common EwS susceptibility loci
Recent smell loss is the best predictor of COVID-19 among individuals with recent respiratory symptoms
In a preregistered, cross-sectional study we investigated whether olfactory loss is a reliable predictor of COVID-19 using a crowdsourced questionnaire in 23 languages to assess symptoms in individuals self-reporting recent respiratory illness. We quantified changes in chemosensory abilities during the course of the respiratory illness using 0-100 visual analog scales (VAS) for participants reporting a positive (C19+; n=4148) or negative (C19-; n=546) COVID-19 laboratory test outcome. Logistic regression models identified univariate and multivariate predictors of COVID-19 status and post-COVID-19 olfactory recovery. Both C19+ and C19- groups exhibited smell loss, but it was significantly larger in C19+ participants (mean±SD, C19+: -82.5±27.2 points; C19-: -59.8±37.7). Smell loss during illness was the best predictor of COVID-19 in both univariate and multivariate models (ROC AUC=0.72). Additional variables provide negligible model improvement. VAS ratings of smell loss were more predictive than binary chemosensory yes/no-questions or other cardinal symptoms (e.g., fever). Olfactory recovery within 40 days of respiratory symptom onset was reported for ~50% of participants and was best predicted by time since respiratory symptom onset. We find that quantified smell loss is the best predictor of COVID-19 amongst those with symptoms of respiratory illness. To aid clinicians and contact tracers in identifying individuals with a high likelihood of having COVID-19, we propose a novel 0-10 scale to screen for recent olfactory loss, the ODoR-19. We find that numeric ratings â€2 indicate high odds of symptomatic COVID-19 (4<10). Once independently validated, this tool could be deployed when viral lab tests are impractical or unavailable
More than smell - COVID-19 is associated with severe impairment of smell, taste, and chemesthesis
Recent anecdotal and scientific reports have provided evidence of a link between COVID-19 and chemosensory impairments such as anosmia. However, these reports have downplayed or failed to distinguish potential effects on taste, ignored chemesthesis, generally lacked quantitative measurements, were mostly restricted to data from single countries. Here, we report the development, implementation and initial results of a multi-lingual, international questionnaire to assess self-reported quantity and quality of perception in three distinct chemosensory modalities (smell, taste, and chemesthesis) before and during COVID-19. In the first 11 days after questionnaire launch, 4039 participants (2913 women, 1118 men, 8 other, ages 19-79) reported a COVID-19 diagnosis either via laboratory tests or clinical assessment. Importantly, smell, taste and chemesthetic function were each significantly reduced compared to their status before the disease. Difference scores (maximum possible change+/-100) revealed a mean reduction of smell (-79.7+/- 28.7, mean+/- SD), taste (-69.0+/- 32.6), and chemesthetic (-37.3+/- 36.2) function during COVID-19. Qualitative changes in olfactory ability (parosmia and phantosmia) were relatively rare and correlated with smell loss. Importantly, perceived nasal obstruction did not account for smell loss. Furthermore, chemosensory impairments were similar between participants in the laboratory test and clinical assessment groups. These results show that COVID-19-associated chemosensory impairment is not limited to smell, but also affects taste and chemesthesis. The multimodal impact of COVID-19 and lack of perceived nasal obstruction suggest that SARS-CoV-2 infection may disrupt sensory-neural mechanisms.Additional co-authors: Veronica Pereda-Loth, Shannon B Olsson, Richard C Gerkin, Paloma Rohlfs DomĂnguez, Javier Albayay, Michael C. Farruggia, Surabhi Bhutani, Alexander W Fjaeldstad, Ritesh Kumar, Anna Menini, Moustafa Bensafi, Mari Sandell, Iordanis Konstantinidis, Antonella Di Pizio, Federica Genovese, Lina ĂztĂŒrk, Thierry Thomas-Danguin, Johannes Frasnelli, Sanne Boesveldt, Ăzlem Saatci, Luis R. Saraiva, Cailu Lin, JĂ©rĂŽme Golebiowski, Liang-Dar Hwang, Mehmet Hakan Ozdener, Maria Dolors GuĂ rdia, Christophe Laudamiel, Marina Ritchie, Jan HavlĂcek, Denis Pierron, Eugeni Roura, Marta Navarro, Alissa A. Nolden, Juyun Lim, KL Whitcroft, Lauren R. Colquitt, Camille Ferdenzi, Evelyn V. Brindha, Aytug Altundag, Alberto Macchi, Alexia Nunez-Parra, Zara M. Patel, SĂ©bastien Fiorucci, Carl M. Philpott, Barry C. Smith, Johan N Lundström, Carla Mucignat, Jane K. Parker, Mirjam van den Brink, Michael Schmuker, Florian Ph.S Fischmeister, Thomas Heinbockel, Vonnie D.C. Shields, Farhoud Faraji, Enrique Enrique SantamarĂa, William E.A. Fredborg, Gabriella Morini, Jonas K. Olofsson, Maryam Jalessi, Noam Karni, Anna D'Errico, Rafieh Alizadeh, Robert Pellegrino, Pablo Meyer, Caroline Huart, Ben Chen, Graciela M. Soler, Mohammed K. Alwashahi, Olagunju Abdulrahman, Antje Welge-LĂŒssen, Pamela Dalton, Jessica Freiherr, Carol H. Yan, Jasper H. B. de Groot, Vera V. Voznessenskaya, Hadar Klein, Jingguo Chen, Masako Okamoto, Elizabeth A. Sell, Preet Bano Singh, Julie Walsh-Messinger, Nicholas S. Archer, Sachiko Koyama, Vincent Deary, HĂŒseyin Yanik, Samet Albayrak, Lenka Martinec NovĂĄkov, Ilja Croijmans, Patricia Portillo Mazal, Shima T. Moein, Eitan Margulis, Coralie Mignot, Sajidxa Mariño, Dejan Georgiev, Pavan K. Kaushik, Bettina Malnic, Hong Wang, Shima Seyed-Allaei, Nur Yoluk, Sara Razzaghi, Jeb M. Justice, Diego Restrepo, Julien W Hsieh, Danielle R. Reed, Thomas Hummel, Steven D Munger, John E Haye
Les formations professionnelles et la ville
Parce quâelles impliquent un ensemble de comportements dâindividus et de groupes humains qui assurent une reproduction Ă©largie des savoirs et des savoir-faire nĂ©cessaires Ă la vie Ă©conomique et sociale, les formations professionnelles sont au centre du fonctionnement des sociĂ©tĂ©s. Ă leurs dimensions dâinstruments de rĂ©alisation de projets individuels et de facteurs de compĂ©titivitĂ© pour les entreprises, sâajoute un aspect structurant pour les sites oĂč existent et se dĂ©veloppent des moyens de ..
Ouverture : De la formation territorialisée à la formation des territoires
Pierron Robert. Ouverture : De la formation territorialisée à la formation des territoires. In: Formation Emploi. N.84, 2003. pp. 5-10
Introduction : Au-delĂ du clivage entre politique de l'emploi et dispositifs de formation ?
Pierron Robert. Introduction : Au-delĂ du clivage entre politique de l'emploi et dispositifs de formation ? . In: Formation Emploi. N.70, 2000. Emplois-jeunes : quelle professionnalisation ? pp. 5-8
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