117 research outputs found
Peran Wanita dalam Rumah Tangga Penganut Hindu Dharma Desa Pepuro Barat Kecamatan Wotu Kabupaten Luwu Timur
Hasil penelitian ini menunjukkan bahwa gambaran kehidupan rumah tangga Penganut Hindu Dharma di Desa Pepuro Barat Kecamatan Wotu Kabupaten Luwu Timur ialah wanita di desa ini memiliki perbedaan dengan wanita yang ada di sekitarannya yaitu wanita bugis, dalam kehidupan sehariharinya wanita penganut Hindu Dharma lebih kuat dalam hal mencari nafkah. Kemudian dalam hal keagamaannya mereka mempercaya Kitab Weda sebagai pedoman dalam kehidupannya, dan berasaskan pada empat jalan yakni, Karma marga, Bakti Marga, Raja Marga, dan Jenana Marga. Yakni dipercayakan bahwa empat jalan itu menuju surga. Wanita Hindu Dharma berperan aktif dalam memenuhi kebutuhan rumah tangganya dikarenakan itu sudah merupakan budaya mereka yang turun temurun dari Nenek Moyang, dan memang harus dilakukan karena mayoritas wanita di sana seperti itu. Serta sebagai bentuk baktinya kepada suami
First-principles flocculation as the key to low energy algal biofuels processing.
This document summarizes a three year Laboratory Directed Research and Development (LDRD) program effort to improve our understanding of algal flocculation with a key to overcoming harvesting as a techno-economic barrier to algal biofuels. Flocculation is limited by the concentrations of deprotonated functional groups on the algal cell surface. Favorable charged groups on the surfaces of precipitates that form in solution and the interaction of both with ions in the water can favor flocculation. Measurements of algae cell-surface functional groups are reported and related to the quantity of flocculant required. Deprotonation of surface groups and complexation of surface groups with ions from the growth media are predicted in the context of PHREEQC. The understanding of surface chemistry is linked to boundaries of effective flocculation. We show that the phase-space of effective flocculation can be expanded by more frequent alga-alga or floc-floc collisions. The collision frequency is dependent on the floc structure, described in the fractal sense. The fractal floc structure is shown to depend on the rate of shear mixing. We present both experimental measurements of the floc structure variation and simulations using LAMMPS (Large-scale Atomic/Molecular Massively Parallel Simulator). Both show a densification of the flocs with increasing shear. The LAMMPS results show a combined change in the fractal dimension and a change in the coordination number leading to stronger flocs
Quantification of basin-floor fan pinchouts: examples from the Karoo Basin, South Africa
The topography of the seabed (orientation and gradient) and rheology of the flows greatly influences the character of basin-floor turbidity current deposits. Therefore, submarine fan pinchouts can help to constrain seabed topography and flow behavior at the time of deposition. Although the depositional architecture of submarine lobe pinchouts has been documented in various basin-fills, the quantification of the rates of change at pinchouts in different paleogeographic positions and basin configurations has not been attempted previously. Here, we utilize extensive outcrops and research boreholes from the oblique up-dip pinchout of Fans 3 and 4 and the lateral pinchout of Fan 3 in the Tanqua depocenter, Karoo Basin, South Africa, to compare sedimentary facies and to quantify the rates of change in gross interval thickness. At the oblique up-dip pinchout, Fan 3 thins abruptly at a rate of 12 m/km, while Fan 4 thins at a rate of 4 m/km. Marked differences between Fans 3 and 4 in sedimentary facies and architecture toward the up-dip pinchout, with termination of lobes in Fan 3 and a channel-lobe transition zone and external levee in Fan 4, suggests progradation of the system. The thinning rate of the lateral pinchout of Fan 3 is 2 m/km, with the presence of hybrid beds in the lower part of Fan 3, while the upper part is dominated by structured sandstones and thin-bedded heterolithics. The variations in facies suggest that lobe-scale frontal and lateral pinchouts are stacked at the lobe complex-scale lateral pinchout of Fan 3, highlighting the importance of a hierarchical understanding when studying basin-floor fan pinchouts. The quantified rates of change in fan thickness and sedimentology on the oblique up-dip and lateral fan pinchouts are markedly different. Contrasting pinchout architecture above slopes with subtle differences in gradient and orientation cautions against the simple definition of reservoir input parameters for stratigraphic traps in submarine fan systems
Disconnected submarine lobes as a record of stepped slope evolution over multiple sea-level cycles
The effects of abrupt changes in slope angle and orientation on turbidity current behavior have been investigated in numerous physical and numerical experiments and examined in outcrop, subsurface, and modern systems. However, the long-term impact of subtle and evolving seabed topography on the stratigraphic architecture of deep-water systems requires fine-scale observations and extensive 3-D constraints. This study focuses on the Permian Laingsburg and Fort Brown formations, where multiple large sand-rich systems (Units AâF) have been mapped from entrenched slope valleys, through channel-levee systems, to basin-floor lobe complexes over a 2500 km2 area. Here, we investigate three thinner (typically <5 m in thickness) and less extensive sand-rich packages, Units A/B, B/C, and D/E, between the large-scale systems. Typically, these sand-rich units are sharp-based and topped, and contain scours and mudstone clast conglomerates that indicate deposition from high-energy turbidity currents. The mapped thickness and facies distribution suggest a lobate form. These distinctive units were deposited in similar spatial positions within the basin-fill and suggest similar accommodation patterns on the slope and basin floor prior to the larger systems (B, C, and E). Stratigraphically, these thin units represent the first sand deposition following Âmajor periods of shut-down in sediment supply, and are interpreted as marking a partial re-establishment of sand delivery pathways creating âdisconnected lobesâ that are fed mainly by flows sourced from failures on the shelf and upper slope rather than major feeder channel-levee systems.
Thickness and facies patterns throughout the deep-water stratigraphy suggest seabed topography was present early in the basin formation and maintained persistently in a similar area to ultimately form a stepped slope profile. The stepped slope profile evolved through three key stages of development: Phase 1, where sediment supply exceeds deformation rate (likely caused by differential subsidence); Phase 2, where sediment supply is on average equal to deformation rate; and Phase 3, where deformation rate outpaces sediment supply. This study demonstrates that smaller systems are a sensitive record of evolving seabed topography and they can consequently be used to recreate more accurate paleotopographic profiles
Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19
IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19.
Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19.
DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 nonâcritically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022).
INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (nâ=â257), ARB (nâ=â248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; nâ=â10), or no RAS inhibitor (control; nâ=â264) for up to 10 days.
MAIN OUTCOMES AND MEASURES The primary outcome was organ supportâfree days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes.
RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ supportâfree days among critically ill patients was 10 (â1 to 16) in the ACE inhibitor group (nâ=â231), 8 (â1 to 17) in the ARB group (nâ=â217), and 12 (0 to 17) in the control group (nâ=â231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ supportâfree days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively).
CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes.
TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570
Aggregation in colloids and aerosols
Doctor of PhilosophyDepartment of PhysicsAmitabha ChakrabartiThis work is the result of a wide range of computer simulation research into the
aggregation behavior of dispersed colloidal and aerosol particles in a number of different
environments from the continuum to the free-molecular. The goal of this research has
been to provide a bridge between experimental and theoretical researchers in this field by
simulating the aggregation process within a known model. To this end, a variety of interparticle
interactions has been studied in the course of this research, focusing on the effect
of these interactions on the aggregation mechanism and resulting aggregate structures.
Both Monte Carlo and Brownian Dynamics codes have been used to achieve this goal.
The morphologies of clusters that result from aggregation events in these systems have
been thoroughly analyzed with a range of diverse techniques, and excellent agreement
has been found with other researchers in this field. Morphologies of these clusters
include fractal, gel, and crystalline forms, sometimes within the same structure at
different length scales. This research has contributed to the fundamental understanding of
aggregation rates and size distributions in many physical system, having allowed for the
development of improved models of the aggregation and gelation process. Systems
studied include DLCA and BLCA in two and three dimension, free-molecular diffusional
(Epstein) system, selective aggregation in binary colloids, ssDNA mediated aggregation
in colloidal systems, and several others
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