32 research outputs found
A novel method for power analysis and sample size determination in metabolic phenotyping
- Author
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- 26/04/2016
- Field of study
The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans
- Author
- Abbara Ali
- Bassett Paul
- Bech Paul
- Bugliani Marco
- Camuzeaux Stephane
- Carrat Gaelle
- Clarke Sophie A.
- Comninos Alexander N.
- Dhillo Waljit S.
- Eng Pei Chia
- Godsland Ian F.
- Gomez-Romero Maria
- Holmes Elaine
- Hu Ming
- Hughes Stephen J.
- Izzi-Engbeaya Chioma
- James Shapiro A. M.
- Johnson Paul R.
- Jomard Anne
- Jones Sophie
- Lewis Matthew R.
- Marchetti Piero
- Narayanaswamy Shakunthala
- Nicholson Jeremy K.
- Papadopoulou Deborah
- Pearce Jake T. M.
- Piemonti Lorenzo
- Prague Julia K.
- Ratnasabapathy Risheka
- Rutter Guy A.
- Sands Caroline
- Tan Tricia
- Yang Lisa
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
Aims: To investigate the effect of kisspeptin on glucose-stimulated insulin secretion and appetite in humans. Materials and methods: In 15 healthy men (age: 25.2 ± 1.1 years; BMI: 22.3 ± 0.5 kg m−2), we compared the effects of 1 nmol kg−1 h−1 kisspeptin versus vehicle administration on glucose-stimulated insulin secretion, metabolites, gut hormones, appetite and food intake. In addition, we assessed the effect of kisspeptin on glucose-stimulated insulin secretion in vitro in human pancreatic islets and a human β-cell line (EndoC-βH1 cells). Results: Kisspeptin administration to healthy men enhanced insulin secretion following an intravenous glucose load, and modulated serum metabolites. In keeping with this, kisspeptin increased glucose-stimulated insulin secretion from human islets and a human pancreatic cell line in vitro. In addition, kisspeptin administration did not alter gut hormones, appetite or food intake in healthy men. Conclusions: Collectively, these data demonstrate for the first time a beneficial role for kisspeptin in insulin secretion in humans in vivo. This has important implications for our understanding of the links between reproduction and metabolism in humans, as well as for the ongoing translational development of kisspeptin-based therapies for reproductive and potentially metabolic conditions
The state of the Martian climate
- Author
- Aaron-Morrison Arlene P.
- Ackerman Steven A.
- Adams Nicolaus G.
- Adler Robert F.
- Albanil Adelina
- Alfaro Eric J.
- Allan Rob
- Alves Lincoln M.
- Amador Jorge A.
- Ambrose Barbara J.
- Andreassen L. M.
- Arendt A.
- Arndt Derek S.
- Arzhanova N. M.
- Arévalo Juan
- Aschan M. M.
- Azorin-Molina César
- Banzon Viva
- Bardin M. U.
- Barichivich Jonathan
- Baringer Molly O.
- Barreira Sandra
- Baxter Stephen
- Bazo Juan
- Becker Andreas
- Bedka Kristopher M.
- Behrenfeld Michael J.
- Bell Gerald D.
- Belmont M.
- Benedetti Angela
- Bernhard G.
- Berrisford Paul
- Berry David I.
- Bettolli María L.
- Bhatt Uma S.
- Bidegain Mario
- Bill Brian D.
- Billheimer Sam
- Bissolli Peter
- Blake Eric S.
- Blunden Jessica
- Borch-Johnsen K.
- Bosilovich Michael G.
- Boucher Olivier
- Boudet Dagne R.
- Box Jason E.
- Boyer Tim
- Braathen Geir O.
- Bromwich David H.
- Brown R.
- Bulygina Olga N.
- Burgess D.
- Calderón Blanca
- Camargo Suzana J.
- Campbell Jayaka D.
- Cappelen J.
- Carrasco Gualberto
- Carter Brendan R.
- Chambers Don P.
- Chandler Elise
- Christiansen Hanne H.
- Christy John R.
- Chung Daniel
- Chung E.S.
- Cinque Kathy
- Clem Kyle R.
- Coelho Caio A.
- Cogley J.G.
- Coldewey-Egbers Melanie
- Colwell Steve
- Cooper Owen R.
- Copland L.
- Cosca Catherine E.
- Cross Jessica N.
- Crotwell Molly J.
- Crouch Jake
- Davis Sean M.
- De Eyto Elvira
- De Jeu Richard A.M.
- De Laat Jos
- Degasperi Curtis L.
- Degenstein Doug
- Demircan M.
- Derksen C.
- Destin Dale
- Di Girolamo Larry
- Di Giuseppe F.
- Diamond Howard J.
- Dlugokencky Ed J.
- Dohan Kathleen
- Dokulil Martin T.
- Dolgov A. V.
- Dolman A. Johannes
- Domingues Catia M.
- Donat Markus G.
- Dong Shenfu
- Dorigo Wouter A.
- Dortch Quay
- Doucette Greg
- Drozdov Dmitry S.
- Ducklow Hugh
- Dunn Robert J.H.
- Durán-Quesada Ana M.
- Dutton Geoff S.
- Ebrahim A.
- Elkharrim M.
- Elkins James W.
- Espinoza Jhan C.
- Etienne-Leblanc Sheryl
- Evans Thomas E.
- Famiglietti James S.
- Farrell S.A.
- Fateh S.
- Fausto Robert S.
- Fedaeff Nava
- Feely Richard A.
- Feng Z.
- Fenimore Chris
- Fettweis Xavier
- Fioletov Vitali E.
- Flemming Johannes
- Fogarty Chris T.
- Fogt Ryan L.
- Folland Chris
- Fonseca C.
- Fossheim M.
- Foster Michael J.
- Fountain Andrew
- Francis S. D.
- Franz Bryan A.
- Frey Richard A.
- Frith Stacey M.
- Froidevaux Lucien
- Ganter Catherine
- Garzoli Silvia
- Gerland S.
- Gilbert Kristin
- Gobron Nadine
- Goldenberg Stanley B.
- Gomez R. Sorbonne
- Goni Gustavo J.
- Goto A.
- Griffin Jessicca
- Grooß J. U.
- Gruber Alexander
- Guard Charles Chip
- Gugliemin Mauro
- Gupta S. K.
- Gutiérrez J. M.
- Hagos S.
- Hahn Sebastian
- Haimberger Leo
- Hakkarainen J.
- Hall Brad D.
- Halpert Michael S.
- Hamlington Benjamin D.
- Hanna Edward
- Hansen K.
- Hanssen-Bauer I.
- Harris Ian A
- Heidinger Andrew K.
- Heikkilä A.
- Heil A.
- Heim Richard R., Jr.
- Hendricks S.
- Hernández Marieta
- Hidalgo Hugo G.
- Hilburn Kyle
- Ho Shu Peng Ben
- Holmes R. Max
- Hu Zeng Zhen
- Huang Boyin
- Huelsing Hannah K.
- Huffman George J.
- Hughes N.C.
- Hurst Dale F.
- Ialongo I.
- Ijampy J. A.
- Ingvaldsen R. B.
- Inness Antje
- Isaksen K.
- Ishii Masayoshi
- Jevrejeva Svetlana
- Jiménez C.
- Jin Xiangze
- Johannesen E.
- John Viju
- Johnson Bryan
- Johnson Gregory C.
- Jones Philip D.
- Joseph Annie C.
- Jumaux Guillaume
- Kabidi Khadija
- Kaiser Johannes W.
- Kato Seiji
- Kazemi A.
- Keller Linda M.
- Kendon Mike
- Kennedy John J.
- Kerr Kenneth
- Kholodov A. L.
- Khoshkam Mahbobeh
- Killick Rachel
- Kim Hyungjun
- Kim S. J.
- Kimberlain Todd B.
- Klotzbach Philip J.
- Knaff John A.
- Kobayashi Shinya
- Kohler J.
- Korhonen Johanna
- Korshunova Natalia N.
- Kovacs K.M.
- Kramarova Natalya
- Kratz David P.
- Kruger Andries
- Kruk Michael C.
- Kudela Raphael
- Kumar Arun
- Lakatos M.
- Lakkala K.
- Lander Mark A.
- Landsea Chris W.
- Lankhorst Matthias
- Lantz Kathleen
- Lazzara Matthew A.
- Lemons P.
- Leuliette Eric
- Lieser Jan L.
- Lin I. I.
- Liu Hongxing
- Liu Yinghui
- Lo Monaco Claire
- Locarnini Ricardo
- Loeb Norman G.
- Long Craig S.
- Lorrey Andrew M.
- Love-Brotak S. Elizabeth
- Loyola Diego
- Lumpkin Rick
- Luo Jing-Jia
- Luojus K.
- Lydersen C.
- Lyman John M.
- López Álvarez Luis Alfonso
- L’Heureux Michelle
- Maberly Stephen C.
- Maddux Brent C.
- Malheiros Ramos Andrea
- Malkova G. V.
- Manney G.L.
- Marcellin Vernie
- Marchenko Sergey
- Marengo José A.
- Marra John J.
- Marszelewski Wlodzimierz
- Martens B.
- Martínez-Güingla Rodney
- Massom Robert A.
- Mata Mauricio M.
- Mathis Jeremy T.
- May Linda
- Maycock Tom
- Mayer Michael
- Mazloff Matthew
- McBride Charlotte
- McCabe M.F.
- McCarthy M.
- McClelland J.W.
- McGree Simon
- McVicar Tim R.
- Mears Carl A.
- Meier Walt
- Meinen Christopher S.
- Mekonnen A.
- Mengistu Tsidu G.
- Menzel W. Paul
- Menéndez Melisa
- Merchant Christopher J.
- Meredith Michael P.
- Merrifield Mark A.
- Metzl N.
- Minnis Patrick
- Miralles Diego G.
- Misch Deborah J.
- Mistelbauer T.
- Mitchum Gary T.
- Monselesan Didier
- Monteiro Pedro M S
- Montzka Stephen A.
- Morice Colin
- Mote Thomas
- Mudryk L.
- Mullan A. Brett
- Mühle Jens
- Nash Eric R.
- Naveira-Garabato Alberto C.
- Nerem Steven R.
- Newman Paul A.
- Nieto Juan José
- Noetzli Jeannette
- Osborn Tim J.
- Osborne Susan
- Overland James
- Oyunjargal Lamjav
- O’Neel S.
- Parinussa Robert M.
- Park E. Hyung
- Parker David
- Parrington M.
- Parsons A. Rost
- Pasch Richard J.
- Pascual-Ramírez Reynaldo
- Paterson Andrew M.
- Paulik Christoph
- Pearce Petra R.
- Pelto Mauri S.
- Peng Liang
- Perkins-Kirkpatrick Sarah E.
- Perovich Donald
- Petropavlovskikh Irina
- Pezza Alexandre B.
- Phillips David
- Pinty Bernard
- Pitts Michael C.
- Pons M. R.
- Porter Avalon O.
- Primicerio R.
- Proshutinsky A.
- Quegan Sean
- Quintana Juan
- Rahimzadeh Fatemeh
- Rajeevan Madhavan
- Randriamarolaza L.
- Razuvaev Vyacheslav N.
- Reagan James R.
- Reid Phillip
- Reimer Christoph
- Renwick James A.
- Revadekar Jayashree V.
- Richter-Menge Jacqueline
- Riddle Deborah B.
- Riffler Michael
- Rimmer Alon
- Rintoul Steve
- Robinson David A.
- Rodell Matthew
- Rodríguez Solís José L.
- Romanovsky Vladimir E.
- Ronchail Josyane
- Rosenlof Karen H.
- Roth Chris
- Rusak James A.
- Rémy Samuel
- Sabine Christopher L.
- Sallée Jean Bapiste
- Santee Michelle L.
- Sawaengphokhai P.
- Sayouri Amal
- Scambos Ted A.
- Schemm Jae
- Schladow S. Geoffrey
- Schmid Claudia
- Schmid Martin
- Schmidtko Sunke
- Schreck Carl J.
- Selkirk H. B.
- Send Uwe
- Sensoy Serhat
- Setzer Alberto
- Sharp M.
- Shaw Adrian
- Shi Lei
- Shiklomanov A. I.
- Shiklomanov Nikolai I.
- Siegel David A.
- Signorini Sergio R.
- Sima Fatou
- Simmons Adrian J.
- Smeets C. J.P.P.
- Smith Sharon L.
- Spence Jaqueline M.
- Sprain Mara
- Srivastava A. K.
- Stackhouse Paul W., Jr.
- Stammerjohn Sharon
- Steinbrecht Wolfgang
- Stella José L.
- Stengel Martin
- Stennett-Brown Roxann
- Stephenson Tannecia S.
- Strahan Susan
- Streletskiy D. A.
- Sun-Mack Sunny
- Swart Sebastiaan
- Sweet William
- Sánchez-Lugo Ahira
- Talley Lynne D.
- Tamar Gerard
- Tank S.E.
- Taylor Michael A.
- Tedesco M.
- Teubner Katrin
- Thoman R. L.
- Thompson Philip
- Thomson L.
- Timmermans M. L.
- Tirnanes Joaquin A.
- Tobin Skie
- Trachte Katja
- Trainer Vera L.
- Tretiakov M.
- Trewin Blair C.
- Trotman Adrian R.
- Tschudi M.
- van As D.
- van de Wal R.S.W.
- van der A Ronald J.
- Van Der Schalie Robin
- Van Der Schrier Gerard
- Van Der Werf Guido R.
- Van Meerbeeck Cedric J.
- Veasey Sara W.
- Velicogna I.
- Verburg Piet
- Vigneswaran Bala
- Vincent Lucie A.
- Volkov Denis
- Vose Russell S.
- Wagner Wolfgang
- Wahr John
- Walsh John
- Wang Chunzai
- Wang Junhong
- Wang Lei
- Wang M.
- Wang Sheng-Hung
- Wanninkhof Rik
- Watanabe Shohei
- Weber Mark
- Weller Robert A.
- Weyhenmeyer Gesa A.
- Whitewood Robert
- Wijffels Susan E.
- Wilber Anne C.
- Wild Jeanette D.
- Willett Kate M.
- Williams Michael J.M.
- Willie Shem
- Wolken Gabriel
- Wong Takmeng
- Wood E. F.
- Woolway R. Iestyn
- Wouters B.
- Wåhlin Anna
- Xue Yan
- Yamada Ryuji
- Yim So Young
- Yin Xungang
- Young Steven H.
- Young Teresa
- Yu Lisan
- Zahid H.
- Zambrano Eduardo
- Zhang Peiqun
- Zhao Guanguo
- Zhou Lin
- Ziemke Jerry R.
- Publication venue
- 'American Meteorological Society'
- Publication date
- 01/01/2016
- Field of study
60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes
<i>TESS</i> Spots a Compact System of Super-Earths around the Naked-eye Star HR 858
- Author
- Addison Brett
- Becker Juliette C.
- Bieryla Allyson
- Bowler Brendan P.
- Briceño Cesar
- Brown Timothy M.
- Burke Christopher J.
- Burt Jennifer A.
- Caldwell Douglas A.
- Clark Jake T.
- Crossfield Ian
- Dittmann Jason A.
- Dynes Scott
- Fulton Benjamin J.
- Guerrero Natalia
- Harbeck Daniel
- Horner Jonathan
- Huang Chelsea X.
- Jenkins Jon M.
- Kane Stephen R.
- Kielkopf John
- Kraus Adam L.
- Kreidberg Laura
- Latham David W.
- Law Nicolas
- Mann Andrew W.
- Mengel Matthew W.
- Morton Timothy D.
- Okumura Jack
- Pearce Logan A.
- Plavchan Peter
- Quinn Samuel N.
- Rabus Markus
- Ricker George R.
- Rodriguez Joseph E.
- Rose Mark E.
- Rowden Pam
- Seager Sara
- Shporer Avi
- Siverd Robert J.
- Smith Jeffrey C.
- Stassun Keivan
- Tinney C. G.
- Vanderburg Andrew
- Vanderspek Roland K.
- Winn Joshua N.
- Wittenmyer Rob
- Wright Duncan J.
- Zhang Hui
- Zhou George
- Ziegler Carl A.
- Publication venue
- 'American Astronomical Society'
- Publication date
- 15/07/2019
- Field of study
Transiting Exoplanet Survey Satellite (TESS) observations have revealed a compact multiplanet system around the sixth-magnitude star HR 858 (TIC 178155732, TOI 396), located 32 pc away. Three planets, each about twice the size of Earth, transit this slightly evolved, late F-type star, which is also a member of a visual binary. Two of the planets may be in mean motion resonance. We analyze the TESS observations, using novel methods to model and remove instrumental systematic errors, and combine these data with follow-up observations taken from a suite of ground-based telescopes to characterize the planetary system. The HR 858 planets are enticing targets for precise radial velocity observations, secondary eclipse spectroscopy, and measurements of the Rossiter–McLaughlin effect
The development and validation of a scoring tool to predict the operative duration of elective laparoscopic cholecystectomy
- Author
- Aawsaj Yousif
- Abayomi Michael
- Acharya Vikas
- Aggarwal Smeer Kumar
- Ahmad Anwar
- Ahmed Irfan
- Ahmed Jamil
- Ahmed Javed
- Ahmed Talat
- Ainley Paul
- Akhtar Mansoor
- Al Amari Khalid
- Al-Abed Yahya A.
- Al-Akash Musallam
- Al-Bahrani Ahmed Z.
- Al-Khyatt Waleed
- Al-Muhktar Ahmed
- Al-Sarireh Bilal
- Al-Taan Omer
- Alagaratnam Swethan
- Alam Imran
- Alberts Justin
- Alderson Derek
- Aldridge Roland C.
- Aleksandrov Danail
- Ali Haythem
- Ali Shahda
- Amin Khalid
- Andrew David R.
- Appleton Shaun
- Arhi Chanpreet
- Aroori Somaiah
- Aryal Kamal
- Asad Mehek
- Aseem Rabiya
- Asprou Fotini M.
- Awan Altaf
- Ayaani Soofiyah
- Aymon null
- Babu Benoy I.
- Bajwa Dalvir S.
- Bajwa Farrukh M.
- Baker Andrew L.
- Balfe Paul
- Ball William R.
- Ballance Laura
- Banwell Victoria
- Barnes James
- Barrie Jenifer
- Bartlett Francis
- Basheer Mohammed
- Bashir Gareth
- Basra Melvinder
- Basu Sanjoy
- Basynat Pradeep
- Batt Jeremy
- Bausbacher Harald
- Bawa Sadiq
- Beasley William D.
- Belding Rowena
- Bellini Maria Irene
- Bennett Stephen P.
- Bhandari Santosh
- Bharamgoudar Reshma
- Bhattacharya Vish
- Blane Christine
- Blazeby Jane M.
- Boal Matthew
- Boddy Alexander
- Boland Michael
- Bond-Smith Giles
- Booth Michael I.
- Borowski David W.
- Bowen Laura
- Boyce Kathryn M.
- Boyd Alan T.
- Bradley Donal
- Bradley Neil
- Brennan Stephen
- Brett Daniel
- Broadhurst Jack
- Brooke Eleanor
- Brown Timothy H.
- Bryant Alice
- Buchan Joanna
- Bullen Naomi
- Bunnell Catherine
- Bunting David M.
- Burke Paul
- Byrne James P.
- Byrnes Colman K.
- Campbell William
- Carney Kate
- Carney Kate
- Carroll Paul
- Carter C. Ross
- Carter Nicholas C.
- Carty Nick
- Cassidy John T.
- Chambers Adam
- Chambers Alice
- Chambers Alice
- Chan Wei Ming
- Chang Jessica
- Charalabopoulos Alexandros
- Chauhan Neal
- Cheung Melanie
- Chhabra Alok
- Chishti Imran A.
- Chitre Vivek
- Choy Alfred
- Cieplucha Krzysztos
- Clements Joshua M.
- Coats Maria
- Cockbain Andrew J.
- Coe Peter O.
- Connelly Martin
- Cooke Fiachra
- Courtney Michael J.
- Cowley Jonathan B.
- Cross Keith S.
- Cuming Tamzin
- Cunha Pedro
- Dalgaty Faith
- Dar Farooq
- Date Ravindra
- Dave Rajiv V.
- Davey Phil
- Davies James
- Dawson Suzanne
- De Marchi Joshua A.
- de Siqueira Jonathan
- Deguara Jean
- Delisle Theo G.
- Dennison A. R.
- Derbyshire Laura
- Devoto Laurence
- Dhillon Ajit
- Diamond Tom
- Dickson-Lowe Richard
- Digney Ruairi
- Dindyal Shiva
- Dobbins Brian
- Doe Matthew
- Dorrian Emmet
- Doulias Triantafyllos
- Downing Justine
- Drake Benjamin
- Driscoll Peter J.
- Duke Diana
- Durkin Damien
- Dwerryhouse Simon J.
- D’Costa Conrad
- Ebdewi Hamdi
- Ebied Husam
- Eisawi Abdalla
- El-Dhuwaib Yesar
- El-Hasani Shamsi S.
- Elkheir Natalie
- Elmasry Mohamed
- Elsayed Mohammed
- Elshaer Mohamed
- Emesih Sophie
- Farag Sameh F.
- Farooq Ansar
- Farouk Marwan
- Fasih Tani
- Fawole Adeshina S.
- Fenwick Stephen
- Ferguson Graeme
- Ferris Paul
- Finch David
- Finch J. G.
- Finlay Ian
- Fleming Katie
- Fletcher Ted
- Fordham Imogen J.
- Forouzanfar Amir
- Forrest Craig R.
- Forster Luke
- Fothergill Laura
- Frame Richard J.
- Francombe James
- Frank Lucinda
- Fusai Guiseppe
- Galanopoulos Giorgios
- Gallagher Paul V.
- Garcea Giuseppe
- Gardner-Thorpe James
- Geoghegan Justin G.
- Geogloma Ileana
- Gerakopoulos Stratos
- Ghareeb Essam
- Ghazanfar Mudassar A.
- Gibson Simon
- Giles Mathew
- Giovinazzo Francesco
- Giwa Lola
- Goh Yan Li
- Gopalswamy Sivakumar
- Goscimski Andrzej
- Gossage James A.
- Gough Martin
- Gould Laura
- Gould Laura
- Grant Alan J.
- Gravante Gianpiero
- Griffiths Ewen
- Griffiths Ewen A.
- Gull Sadaf
- Gunasekera Rohan T.
- Gurung Kabita
- Guthrie Graeme J. K.
- Guy Finch J.
- Hafiz Shazia
- Halkias Constantine
- Hall Claire
- Hamady Zayed
- Hamdan Alhafidz
- Hamdan Mohammed F.
- Hamilton Emma
- Hancorn Kate
- Haque Manzarul
- Haque Samer Ul
- Hardy Thomas J.
- Hargreaves Anita
- Harilingam Mohan
- Harris Andrew
- Harrison Ewen
- Hawkins Helen
- Heath Jonathan
- Hebbar Madhusoodhana
- Henderson Lucy T.
- Henley Natasha
- Heshaishi Mohamed
- Hewes James
- Hewes James C.
- Heywood Nick
- Higgs Simon M.
- Hill Arnold D. K.
- Hindley Caroline
- Hirst Natalie A.
- Hisham Elzanati
- Ho Wei-Min
- Hoban Jennifer R.
- Hodgkins Kathryn A.
- Hodson James
- Holroyd David J.
- Hooks Gareth
- Hopwood Benjamin
- Hornby Steve T.
- Hornsby Jane
- Hosie Kenneth B.
- Hosie Kenneth B.
- Hossack Martin R.
- Hossain Tanvir
- Hoti Emir
- Hou David
- Hrycaiczuk Alex
- Hughes Michael
- Hunter David I.
- Hussain Abdulzahra A.
- Hussain Adnan
- Hussain Anwar
- Hussain Najam
- Iftikhar Syed Yusuf
- Iqbal Nusrat
- Iskandar Edrin
- Issa Eyad
- Ivanovski Ivan
- Jackson Andrew
- Jackson Claire
- Jafferbhoy Sadaf F.
- Jambulingam Periyathambi
- Jamdar Saurabh
- Jamel Sara
- Janeczko Adam
- Jaunoo Shameen
- Jayanthi Naga V. G.
- Jelley Clare
- Jennings Neil A.
- Joel Abraham
- Johnpulle Michelle A.
- Johnston Dorothy
- Johnstone Marianne
- Johnstone Marianne
- Joji Nikita
- Jones Claire
- Jones Elinor
- Jones Gareth H.
- Jones M. Angharad
- Jones Michael J.
- Jones Robert P.
- Jones Steven M.
- Kadhim Abbas
- Kadirkamanathan Sritharan
- Kallaway Charlotte
- Kanakala Venkatesh
- Kanavati Osama
- Kansal Nisheeth
- Kaptanis Sarantos
- Karavadra Babu
- Karim Lawen
- Karunakaran Priyadarssini
- Kaur Parminder
- Kausar Ambareen
- Kelly Michael E.
- Kendal Chris
- Kennedy David
- Kenny Ross
- Keogh Ken
- Khalil Ahmed M.
- Khan Amarah
- Khan Mohammad A.
- Khan Muhammad A. S.
- Khan Raja Basit
- Khan Shabuddin
- Khan Shahab
- Khawaja Amir
- Khawaja Zechan
- Khogali Elmoataz
- Kimble Adam
- Kinghorn Alison
- Kirkham Amanda J.
- Knight Benjamin
- Knight Katrina
- Kourkulos Michail
- Krysztopik Richard
- Kumar Pradeep
- Kynaston James
- Kyriakidis Dimitrios
- Lalla Kushik
- Lambert Joel
- Lammy Simon
- Lane Risha
- Larkin David
- Law Jennifer
- Lawther Roger
- Lazim Taha
- Lee Kathryn
- Lee Matthew
- Leeder Paul
- Lennon Hannah
- Lewis Michael
- Lim Henry C. C.
- Lim Pei J.
- Lindsay David
- Lloyd David
- Lo Christina
- Lodhia Joshil
- Longbotham David A.
- Loughlin Paula
- Lovett Bryony
- Luhmann Andreas
- Luther Ali Alison
- Lyons Emma M.
- Macano Christina A. W.
- MacArtney Matthew
- Macdonald Andrew
- Madanipour Suroosh
- Madbak Khaliel
- Madurska Marta
- Magee Conor J.
- Maguire Donal
- Maharaj Geta
- Majeed Ali
- Malcolm Cathy
- Malde Deep
- Malik Nabeela S.
- Mallik Mekhlola
- Mansour Sami
- Manu Mangta
- Manzelli Antonio
- Marriott Paul
- Martin Jack
- Martin Sean T.
- Martin Serena
- Marudanayagam Ravi
- Mason Denise
- Mathur Pawan
- Mawhinney Abi
- Mbuvi James
- McAree Barry
- McCain Stephen
- McCallum Iain J. D.
- McClarey Andrew
- McCune Ken
- McDermott Frank
- McEntee Gerry P.
- McGlone Emma R.
- McGuigan Andrew
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- Watson Nicholas F.
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- Weber Beatrix
- Weerasinghe Chamindri
- Welbourn Hannah
- Wheatley Kevin
- White Timothy J.
- Wijetunga Imeshi
- Wild Jonathan R. L.
- Wilkinson Marc D.
- Williams Sophie V.
- Williamson Tracey K.
- Willson Peter D.
- Wilson Michael S. J.
- Wilson Timothy R.
- Winter Des C.
- Winter Hannah
- Wood Christopher P. J.
- Wood Peter
- Wood Simon
- Woodman Thomas
- Yahya Salama
- Yao Caroline
- Yeldham Geoffrey
- Yoganathan Thusidaran
- Youssef Haney
- Zafar Sara
- Zafrani Zakhi
- Zarsadias Prizzi
- Zeeshan Saquib
- Zhang Catherine
- Ziprin Paul
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2018
- Field of study
Background: The ability to accurately predict operative duration has the potential to optimise theatre efficiency and utilisation, thus reducing costs and increasing staff and patient satisfaction. With laparoscopic cholecystectomy being one of the most commonly performed procedures worldwide, a tool to predict operative duration could be extremely beneficial to healthcare organisations.
Methods: Data collected from the CholeS study on patients undergoing cholecystectomy in UK and Irish hospitals between 04/2014 and 05/2014 were used to study operative duration. A multivariable binary logistic regression model was produced in order to identify significant independent predictors of long (> 90 min) operations. The resulting model was converted to a risk score, which was subsequently validated on second cohort of patients using ROC curves.
Results: After exclusions, data were available for 7227 patients in the derivation (CholeS) cohort. The median operative duration was 60 min (interquartile range 45–85), with 17.7% of operations lasting longer than 90 min. Ten factors were found to be significant independent predictors of operative durations > 90 min, including ASA, age, previous surgical admissions, BMI, gallbladder wall thickness and CBD diameter. A risk score was then produced from these factors, and applied to a cohort of 2405 patients from a tertiary centre for external validation. This returned an area under the ROC curve of 0.708 (SE = 0.013, p 90 min increasing more than eightfold from 5.1 to 41.8% in the extremes of the score.
Conclusion: The scoring tool produced in this study was found to be significantly predictive of long operative durations on validation in an external cohort. As such, the tool may have the potential to enable organisations to better organise theatre lists and deliver greater efficiencies in care
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- Gui Qi
- Gunaratne Preethi
- Gunning Kate
- Guo Daorong
- Guo Jane
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- Ha Chi
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- Hamilton Matt
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- Hamlett John
- Hammon Nancy
- Hammond Martin
- Hammond Sha
- Hammond Sian
- Hamza Khalid
- Han Guiqing
- Han Shunsheng
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- Hanak Vincent A.
- Hancock Julie
- Harbes Brandy A.
- Harding Adam
- Harkins C. Richard
- Harley Joanne
- Harper David
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- Hashimoto Wakako
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- Haugen Eric
- Haussler David
- Havlak Paul
- Hawes Alicia C.
- Hawkins Ebere Sylvia Onyirioha
- Hawkins Natalie
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- Hewitt Stephen
- Heyen Joshua
- Higgs Douglas
- Hildebrand Carl E.
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- Hillyard Guy
- Hines Sandra
- Hinkins Russell
- Hinrichs Angela S.
- Hitchens Matthew Edward
- Ho Issac
- Ho Sara-Jane
- Hodgson Anne V.
- Hodgson David
- Hoffman Susan M.G.
- Hoffs Michael
- Hogues Marilyn E.
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- Homsi Farah J.
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- Imo Kelvin C.
- Inacio Nicole
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- Ishibashi Akiko
- Ishikawa Sabine K.
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- Kou Zhaohui
- Kovar Christie L.
- Krawczyk Marie-Claude
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- Kruchowski Scott S.
- Kube Michael
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- Lou Yunian
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- Lowenstein Michael G.
- Lowry Stephen
- Lozado Ryan J.
- Lu Lingfeng
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- Lucier Raymond L.
- Ludeman Thom
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- MacLean Christine
- Madabhushi Ramki
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- McMurray Kimberly L.
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- Murayama Yuji
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- Nair Seema R.
- Naka Maho
- Nakagawa Masayo
- Nakagawa Saori
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- Nakato Eriko
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- Nandkeshwar Richard
- Nankervis Colin E.
- Naranjo Cleo M.
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- Nazareth Lynne V.
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- Nwokenkwo Stanley
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- O\u27Donovan Daniel
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- Okumura Reina
- Okwuonu Geoffrey O.
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- Olarnpunsagoon Alisa
- Olivas Jason
- Oliver Hayley
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- Olson Maynard V.
- Omotosho Bamidele
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- Patel Ritesh
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- Paul Shelia
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- Percy Chantel
- Perez Agapito
- Perez Lesette M.
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- Ridler Kerry
- Riethman Harold
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- Rise Cecil
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- Rong Li
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- Wu Chungen
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- Zembeck Lisa
- Zeng Yixin
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- Zhan Guoping
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- Zhang Guangyu
- Zhang Guohua
- Zhang Guohua
- Zhang Haiqing
- Zhang Haiqing
- Zhang Haiqing
- Zhang Hongbo
- Zhang Hongbo
- Zhang Jingjing
- Zhang Jingjing
- Zhang Jingkun
- Zhang Jiuchun
- Zhang Jiuchun
- Zhang Lanzhi
- Zhang Li
- Zhang Li
- Zhang Meihua
- Zhang Meng
- Zhang Ming
- Zhang Qing
- Zhang Ruhua
- Zhang Shaojie
- Zhang Tiezhen
- Zhang Wei
- Zhang Wei
- Zhang Xianglin
- Zhang Xianglin
- Zhang Xiaoliang
- Zhang Xiuqing
- Zhang Yan
- Zhang Yi
- Zhang Yilin
- Zhang Yilin
- Zhang Ying
- Zhang Yuansen
- Zhang Yuzhi
- Zhang Zhengdong
- Zhao Hongmei
- Zhao Lijian
- Zhao Shenru
- Zhao Zhijing
- Zhen Zhicheng
- Zheng Haibo
- Zhong Ming
- Zhou Carol
- Zhou Haixia
- Zhou Jianling
- Zhou Nannan
- Zhou Xinfeng
- Zhou Yan
- Zhou Yang
- Zhou Yi
- Zhu Bingying
- Zhu Bofeng
- Zhu Fenghua
- Zhu Genfeng
- Zhu Genfeng
- Zhu Miao
- Zhu Ning
- Zhu Yongge
- Zhu Zhen
- Zhuang Shitao
- Zierten Deborah
- Zimmer Andrew
- Zody Michael C.
- Zollo Massimo
- Zorrilla Sara E.
- Zuo Lin
- Publication venue
- LSU Digital Commons
- Publication date
- 21/10/2004
- Field of study
The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead
Robust estimation of bacterial cell count from optical density
- Author
- Aarnio Tiu
- Aaron Leow Chung Yong
- Abbas Anser
- Abduraimova Aiganym
- Abraham Doris
- Acar Beliz Leyla
- Acosta Joaquin
- Adler Nina
- Adulyanukosol Natthawut
- Agena Ejouan
- Agena Ethan
- Aggarwal Priya
- Aguirre Adriana Lizeth Rubio
- Ahlgren Christopher
- Ahuja Janvi
- Aizik Dror
- Akbary Mina
- Akinfenwa Akinwumi
- Akingbesote Ngozi D.
- Akova Umut
- Aldo Ferdinan
- Alexopoulos Ioannis
- Allen Lucy
- Alonso Alejandro
- Altarawneh Dina
- Alvarado Andres Benjamin Sanchez
- Ambre Sanika
- Ameziane Annissa
- Amheine Khadija
- Amin Ihya Fakhrurizal
- Amir Sayeda Sakina
- Amstel Chiel van
- An Yongyan
- Anand Nithishwer Mouroug
- Ananthakrishnan Sathvik
- Anderson Karl
- Angel Sagi
- Annem Vidhya
- Anson Chung Tsun Ho
- Anwar Mariam
- Appel Alana
- Araya Lucas
- Armstrong Alexander
- Arora Neha
- Arora Vasu
- Arruda Beck
- Ashwin F Amal Jude
- Astapenka Artur
- Astles Ben
- Astorino Gabe
- Aubry Celine
- Avileli Rebecca
- Azad Mahnaz Sabeta
- Babar Rehmat
- Babu Priyanka
- Badalli Turan
- Badash Lior
- Baichman-Kass Amichai
- Baldwin Geoff S.
- Baltensperger Oliver Andreas
- Bao Guanke
- Bao Minyue
- Baronaite Ugne
- Barrat Leon Michael
- Barrington Seth
- Barshap Alon
- Bartzoka Natalia
- Basu Anubhav
- Basulto Cynthia
- Bath Scott
- Battina Rohith
- Bauersachs Daniel
- Beal Jacob
- Beale Renee
- Beard Eleanor
- Beck Selina
- Becker Evan
- Benavides Samantha Ayde Pena
- Bennis Nicole
- Bete Anna
- Bhatt Darshak
- Bhowmick Shilpa
- Bian Weixin
- Bijman Eline Yafele
- Bindt Felix
- Blas Karla Soto
- Bo Tang
- Boada Yadira
- Boer Meine
- Bohner Ariel
- Borovko Irina
- Bott Amie
- Bouwmeester Susan
- Bowman Kyle
- Boxem Mike
- Boxuan Cheng
- Boyce Kira
- Boyer Jess
- Brasas Valentas
- Brewer Mathew
- Briand William
- Brink Matilda
- Browne Emily
- Buckley-Taylor Russell
- Budhan Stephanie
- Buller Lisa
- Burckhardt Nele
- Burgland Zachary
- Burns Frank
- Burridge Matt
- Burud Hanna Nedreberg
- Buson Felipe Xavier
- Butterfield Tom
- Byagathvalli Gaurav
- Byatt Gabriel
- Byun Sumin
- Caballero Amalia
- Cai Fu
- Cai Niangui
- Caldwell Sarah
- Camacho Yazmin
- Camille Monteil
- Campbell Robert
- Cao Qinhao
- Cao Yixin
- Cao Yuze
- Carrillo Leo
- Carter Jonah
- Casas Alexis
- Castillo Nora Esther Torres
- Castillo Sandra
- Cave John
- Chai Ruochen
- Chamiec-Case Elizabeth
- Chan Janice
- Chan Yuan-Yao
- Chandramouli Priyanka
- Chang Annabel
- Chang Catherine
- Chang Kevin
- Chang Thomas
- Chang Ting-Chen
- Chang Yu-Ci
- Chapman Tyler
- Chater Dounia
- Chau Anthony
- Chavez Benjamin
- Chavez Francisco
- Chehade Ibrahim
- Chen Carmen
- Chen Chih-Chiang
- Chen Ching-Wei
- Chen Janice
- Chen Junhong
- Chen Junyang
- Chen Junyu
- Chen Pei-Hong
- Chen Ryan
- Chen Weixuan
- Chen Yan
- Chen Yi-Cian
- Chen Yifei
- Chen Zhuoyang
- Cheng Cheng
- Cheng Haolun
- Cheng Hsuan
- Cheng Yu-Hong
- Cheng Yu-Hsuan
- Chenxi Liang
- Cherupalla Arjun
- Chi Jordi
- Chi Shumei
- Chiang Jason
- Chiang Woody
- Ching Lai Tsz
- Ching Lam Kai
- Ching Law Hiu
- Ching Luk Hau
- Chinnathambi Sathivel
- Cho Sungwoo
- Choi Lee Sze
- Choi Youngeun
- Chou Ryan
- Chou Ryan
- Chu Wai Yan
- Chua Yah Tse Sabrina
- Chuang Yi-Chien
- Chulkova Nadezhda
- Chun Cheung Man
- Chun Emily
- Chun Ng Tsz
- Cifuentes Rodrigo Hernandez
- Clapper Jude
- Clapper Jude
- Clark Brittany
- Clemente Borja Sanchez
- Clerc Valerian
- Clodomir Christina
- Coates Ryan
- Cohen Katherine
- Colant Noelle
- Coleman Sarah
- Colgan Cian
- Cone Eli
- Corre Christophe
- Costa Ben
- Cott Rachel Van
- Craw Darilyn
- Crispim Larissa de Souza
- Crone Michael Andrew
- Crooijmans Marjolein
- Crosby Laurel Constanti
- Crowley Peter
- Cruz Frida
- Cubukcu Hande
- Culfogienis Dylan
- Czekster Clarissa
- Dai Leijie
- Dalangin Rochelin
- Daniel Benjamin
- Daniels Lea
- Das Neves Laura
- Das Diptatanu
- Davis Christina
- De Silva Nimaya
- Deb Shalini S.
- Deepak Kumar S.
- Deibel Emilie
- Dejoie Julianne
- Dejoux Alice
- DeKloe Jackson
- Del Toro Mariano
- Delalez Nicolas
- Delgadillo Sabrina
- Delhomme Jean
- Demchuk Aubrey
- Deng Nian Ruei
- Deng Rui
- Denter Jennifer
- Deshmukh-Reeves Ed
- Despres Philippe C.
- Devi Velvizhi
- Dhaliwal Gurpreet
- Diaz Fernanda
- Ding Shizhi
- Ding Yiming
- Ding Zhipeng
- Dingyue Tang
- Dirven Yvette
- Dissmann Jil-Sophie
- Do Stephanie
- Dogra Arushi
- Dominguez Viana Isabel Perez
- Dong Dongyang
- Dong Haitao
- Dong Jason
- Dong Shan
- Dong Shan
- Dong Shan
- Dong Shangzhi
- Dong Shangzhi
- Doyle David
- Doyle Shannon
- Dube Alexandre
- Dubuc Emilien
- Dunstan Izzy
- Dusseaux Theodore A.
- Dvorkin Steve
- Edelmayer Marco
- Ehrenworth Amy
- Eidloth Franziska
- Eijkens Bruno
- Eilers Keno
- El Moubayed Yorgo
- Elcin Evrim
- Elias Noel
- Elikan Max
- Ellermeier Craig
- Elliott Hannah
- Elsa Yeung Hoi Lam
- Emilov Kristian
- Espinoza Diego
- Evans Rhys
- Faidh Mohammed
- Falgenhauer Elisabeth
- Fan Catherine
- Fang Chengzhu
- Fang Choco
- Fang Xiangyi
- Farhi Einan
- Farias Sebastian
- Farny Natalie
- Farny Natalie G.
- Farrell Jennifer
- Fassler Jan
- Faurdal David
- Faustova Ilona
- Feng Xinhua
- Fernandez Cesar Ibrahym Rodriguez
- Fierro Daniela Olono
- Figueroa Ana Cristina
- Figueroa Jose Arnulfo Juarez
- Fikry Clara
- Filzen Rachael
- Fischer Matthew
- Fitzgerald Kevin
- Fitzgerald Liza
- Flores Vinicius
- Foda Asmaa
- Fong Yuhui Deborah
- Forman Victor
- Frank Stefanie
- Frankel Eva
- Freire Paulo J. C.
- Friedman Yonatan
- Frohlich Lisa
- Fu Wenhan
- Fu Yousi
- Fuentes Ernie
- Fulton Leah
- Fung Ip Ning
- Fung Yam Shing
- Gabrielli Jacopo
- Gahagan Maddison
- Gaitt Tobias
- Gaizauskaite Aukse
- Gallegos Isabella
- Gamoneda Diego
- Gandhi Rishi
- Gao Cecily
- Garavito Paula
- Garcia Chrismar
- Garcia David
- Garrido Delia
- Garulli Elisa
- Gaspar Camila
- Gaudi Alex
- Ge Gao
- Ge Yubin
- George Stephan
- Gerard Antoine
- Gershater Markus
- Ghosh Souvik
- Giannopoulos Alexandros Dimitriou
- Giannoula Yvoni
- Gilman Daniel Barber James
- Glockner Eleanor
- Goenka Anushya
- Goetz Marley
- Gogineni Namrata
- Gokul [NO FIRST NAME IN SCOPUS]
- Gonzalo Gonzalo Saiz
- Goodson Michael
- Gopaul Deshmukh
- Gou Yanchen
- Govers Jolijn
- Graaf Floor de
- Grace Tsui Shing Yan
- Graves Daniel
- Grazulyte Inga
- Greenwald Matthew
- Gu Jiajun
- Gu Yiheng
- Gu Yining
- Guadagnino Brett
- Guenther James
- Guerassimoff Lea
- Guo Jintao
- Gupta Shreya
- Guptil Chris
- Guseva Anna
- Ha Jacqueline
- Haddock-Angelli Traci
- Haight Travis
- Hale Mitch
- Hamady Carla
- Han Wang
- Han Weitang
- Handal Paola
- Hanrong Zhu
- Hansen Cecilie
- Hao Junyao
- Hao Mei
- Hao Zhengguo
- Haoran Xu
- Haralsvik Anne Kristin
- Hariyani Imtiyaz
- Hartley Zach
- Hassan Sondoss
- Hau Sion
- He Fa
- He Hanker
- He Henry
- He Karen
- He Lindong
- He Menglan
- He Peixiang
- He Yuna
- He Zhien
- Healy Liam
- Heath Emily
- Heger Theresa
- Hei Chan Yick
- Heijningen Franca van
- Heintze Maxime
- Hemmings Sam
- Heng Heng
- Heng Mary
- Henras Anthony
- Herbert Heydy
- Hernandez Ivan Martin
- Hernandez Laura Armero
- Herrmann Max
- Heux Stephanie
- Hewitt Amy
- Hiesinger Marlene
- Hill Kurt
- Hin Chan Lok
- Hin Wong Chung
- Hin Yu Man
- Ho Anthony
- Ho Ng Sze
- Ho Tim
- Hodson Sophie
- Hofer Sebastian
- Holman Olivor
- Holmedal Ingebjorg
- Hong Lai Tsz
- Hong Lee Chi
- Hong Yiquan
- Hong Yirui
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- Yihang Qiu
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- Zhao Tianyan
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- Zhao Yihang
- Zhaoting Li
- Zhecheng Huang
- Zheng Daniel
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- Zhiwei Song
- Zhong Yanling
- Zhou Hanmi
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- Zhou Rui
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- Zhou Yanjun
- Zhou Yi
- Zhou Yinchi
- Zhou Yineng
- Zhou Yuezhang
- Zhou Yuxin
- Zhou Zhiyu
- Zhu Chushu
- Zhu Ke
- Zhu Xueqian
- Zi Lihan
- Zilinskaite Nemira
- Zimmermann Andreas
- Zimmermann Jennifer
- Zirong Zeng
- Ziwei Zhou
- Ziyi Zhao
- Zorrilla Francisco
- Zou Jiahua
- Zukauskaite Kristina
- Zulueta Patricia
- Zvirblyte Justina
- Publication venue
- Publication date
- 01/01/2020
- Field of study
Optical density (OD) is widely used to estimate the density of cells in liquid culture, but cannot be compared between instruments without a standardized calibration protocol and is challenging to relate to actual cell count. We address this with an interlaboratory study comparing three simple, low-cost, and highly accessible OD calibration protocols across 244 laboratories, applied to eight strains of constitutive GFP-expressing E. coli. Based on our results, we recommend calibrating OD to estimated cell count using serial dilution of silica microspheres, which produces highly precise calibration (95.5% of residuals <1.2-fold), is easily assessed for quality control, also assesses instrument effective linear range, and can be combined with fluorescence calibration to obtain units of Molecules of Equivalent Fluorescein (MEFL) per cell, allowing direct comparison and data fusion with flow cytometry measurements: in our study, fluorescence per cell measurements showed only a 1.07-fold mean difference between plate reader and flow cytometry data
Power Analysis and Sample Size Determination in Metabolic Phenotyping
- Author
- Publication venue
- 'American Chemical Society (ACS)'
- Publication date
- Field of study