Journal of Documentation: A Bibliometrics Analysis (2005-2018)

The purpose of this article was to explore the pattern of publications, using bibliometric analysis, of Journal of Documentation for the period of 2005 to 2018. The results of the study shows that a total of 687 articles were published in the 14 years period from 2005 to 2018, with 71 (10.3%) articles being published the highest total in the year 2018. The study confirmed that the maximum number of articles i.e. 304 (43.9%), were published by single authors, out of which, a large number were on research articles. Out of total number of articles published 228 (33.1%) were 16-20 pages in length. Volume number 74 in 2018 had the highest number of citations with a total of 91 (13.6%). In addition, the study confirmed that the highest number of articles were research articles with a total of 493 (71.7), while others were case studies, conceptual studies, literature reviews, viewpoints and technical papers and short communications, etc

Knowledge Sharing Idiosyncrasies of Research Scholars at CCS Haryana Agricultural University, Hisar, India

The main aim of the present study is to investigate the knowledge sharing behaviour of research scholars at Chaudhary Charan Singh Haryana Agricultural University (CCS HAU), Hisar, India. To understand and reveal the knowledge sharing idiosyncrasies of research scholars, various factors have been covered such as knowledge sharing definition, knowledge sharing attitude, communication channels preferred for knowledge sharing, barriers of knowledge sharing, knowledge sharing motivators, and other factors related to knowledge sharing in an academic institution. For the present study, survey method was adopted with the aid of online structured questionnaire for the purpose of data collection. Total 125 research scholars were approached electronically and shared questionnaires through WhatsApp groups and personal e-mails. Out of total 125, 114 valid questionnaires were collected and considered for final analysis, which representing the response rate of about 91.2 per cent. The findings reveals that about 66% of the respondents were in the opinion that sharing knowledge with peers shall benefit all and majority of the respondents possessed a positive attitude towards knowledge sharing and were aware of its importance in their learning process. The face-to-face interaction for sharing knowledge among the respondents is the most preferred communication channel for majority of the respondents (81.58%); however, some major barriers of knowledge sharing among the research scholars have also been noticed. In order to overcome these barriers, the researchers suggest that academic institutions may foster cordial relationship among the research scholars by providing sufficient interaction opportunities. In the end, practical implication of this study has also been discussed

Design and Optimization of Micro-Machined Sierpinski Carpet Fractal Antenna Using Ant Lion Optimization

This study investigates the optimized Sierpinski carpet fractal patch antenna and also explores the possibility of the integration of the proposed design with monolithic microwave integrated circuits. The optimization process has been performed using an ant lion optimization algorithm to achieve the required operating frequency and impedance matching. Further, due to surface waves excitation in the high index substrates used for the antenna design, the performance of the antenna degrades. Therefore, a process of micro-machining has been adopted to overcome this limitation. The micro-machining process creates an air cavity underneath the patch which further creates the low index environment in the patch antenna causing drastic improvement in the performance parameters along with the compatibility with monolithic microwave integrated circuits. The design shows multiple resonance frequencies in X-band and Ku-band. The proposed micro-machined design shows the resonance at 7.9 GHz, 9.6 GHz, 13.6 GHz, and 19 GHz with a maximum gain of 6 dBi.&nbsp

COMPARATIVE ANALYSIS OF MORPHOLOGY AND PHYTOCHEMICAL CONSTITUENTS IN DIFFERENT POPULATIONS AND MORPHOTYPES OF DATURA INNOXIA MILL. AND DATURA METEL L. FROM PUNJAB PLAINS

Objective: Comparative analysis of morphology and phytochemical constituents in different populations and morphotypes of Datura innoxia Mill. and Datura metel L. from Punjab plains.Methods: Morphological analyses of different populations have been done. Methanol extracts of seeds and roots of different populations have been prepared and total phenols, flavonoid contents were measured through spectrophotometry. Antioxidant activity was studied by 2, 2-diphenyl-1- picrylhydrazyl radical scavenging activity and total antioxidant capacity. Two major compounds, caffeic acid and chlorogenic acid were quantified by high-performance thin-layer chromatography (HPTLC) analyses.Results: Two morphotypes of D. metel were reported in the present study. Out of five different populations of D. metel and D. innoxia, the wild populations have more bioactive compound as compared to the cultivated ones from the detailed phytochemical investigation. Pharmacologically important two marker compounds chlorogenic acid and caffeic acid has been identified and quantified by HPTLC technique.Conclusion: Variation in terms of morphology and secondary metabolites exists among the different populations of Datura spp. Among the two plant parts studied, seeds have the maximum amount of bioactive metabolites and antioxidant activity. This study revealed that chlorogenic acid and caffeic acid are the potential polyphenolic compounds in Datura spp. It has been found that the antioxidant activity of plant is due to its polyphenol contents, which provides insight to various researchers to work on it as it imparts health benefit

Clinical Evaluation of Xylazine-Butorphanol-Guaifenesin-Ketamine as Short-Term TIVA in Equines

Xylazine (1.1 mg/kg), butorphanol (0.02 mg/kg), guaifenesin 5% (20 mg/kg), and ketamine (2.2 mg/kg) combinations were able to induce short-term surgical anaesthesia for 23.33 ± 2.57 min in Spiti ponies with excellent to good muscle relaxation and analgesia. Urination and neighing was a constant feature during recovery period. Biphasic P wave, biphasic T wave, and depressed PR segment were common electrocardiographic findings. Biochemical attributes were within physiological limits except a significant increase in ALT values during anaesthesia. The values returned to normal during recovery ruling out any renal or hepatic toxicity. Occasionally, negative T wave, notched P wave, and sinus block were noticed. It is recommended that the anaesthetic combinations xylazine-butorphanol-guaifenesin-ketamine can be safely used for short-term total intravenous anaesthesia (TIVA) in equines under field conditions

Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma

PURPOSE We sought to investigate clinical outcomes of relapsed medulloblastoma and to compare molecular features between patient-matched diagnostic and relapsed tumors. METHODS Children and infants enrolled on either SJMB03 (NCT00085202) or SJYC07 (NCT00602667) trials who experienced medulloblastoma relapse were analyzed for clinical outcomes, including anatomic and temporal patterns of relapse and postrelapse survival. A largely independent, paired molecular cohort was analyzed by DNA methylation array and next-generation sequencing. RESULTS A total of 72 of 329 (22%) SJMB03 and 52 of 79 (66%) SJYC07 patients experienced relapse with significant representation of Group 3 and wingless tumors. Although most patients exhibited some distal disease (79%), 38% of patients with sonic hedgehog tumors experienced isolated local relapse. Time to relapse and postrelapse survival varied by molecular subgroup with longer latencies for patients with Group 4 tumors. Postrelapse radiation therapy among previously nonirradiated SJYC07 patients was associated with long-term survival. Reirradiation was only temporizing for SJMB03 patients. Among 127 patients with patient-matched tumor pairs, 9 (7%) experienced subsequent nonmedulloblastoma CNS malignancies. Subgroup (96%) and subtype (80%) stabilities were largely maintained among the remainder. Rare subgroup divergence was observed from Group 4 to Group 3 tumors, which is coincident with genetic alterations involving MYC, MYCN, and FBXW7. Subgroup-specific patterns of alteration were identified for driver genes and chromosome arms. CONCLUSION Clinical behavior of relapsed medulloblastoma must be contextualized in terms of up-front therapies and molecular classifications. Group 4 tumors exhibit slower biological progression. Utility of radiation at relapse is dependent on patient age and prior treatments. Degree and patterns of molecular conservation at relapse vary by subgroup. Relapse tissue enables verification of molecular targets and identification of occult secondary malignancies

Clinical outcomes and patient-matched molecular composition of relapsed medulloblastoma

© 2021 by American Society of Clinical Oncology. Creative Commons Attribution Non-Commercial No Derivatives 4.0 License: https://creativecommons.org/licenses/by-nc-nd/4.0/Purpose: We sought to investigate clinical outcomes of relapsed medulloblastoma and to compare molecular features between patient-matched diagnostic and relapsed tumors. Methods: Children and infants enrolled on either SJMB03 (NCT00085202) or SJYC07 (NCT00602667) trials who experienced medulloblastoma relapse were analyzed for clinical outcomes, including anatomic and temporal patterns of relapse and postrelapse survival. A largely independent, paired molecular cohort was analyzed by DNA methylation array and next-generation sequencing. Results: A total of 72 of 329 (22%) SJMB03 and 52 of 79 (66%) SJYC07 patients experienced relapse with significant representation of Group 3 and wingless tumors. Although most patients exhibited some distal disease (79%), 38% of patients with sonic hedgehog tumors experienced isolated local relapse. Time to relapse and postrelapse survival varied by molecular subgroup with longer latencies for patients with Group 4 tumors. Postrelapse radiation therapy among previously nonirradiated SJYC07 patients was associated with long-term survival. Reirradiation was only temporizing for SJMB03 patients. Among 127 patients with patient-matched tumor pairs, 9 (7%) experienced subsequent nonmedulloblastoma CNS malignancies. Subgroup (96%) and subtype (80%) stabilities were largely maintained among the remainder. Rare subgroup divergence was observed from Group 4 to Group 3 tumors, which is coincident with genetic alterations involving MYC, MYCN, and FBXW7. Subgroup-specific patterns of alteration were identified for driver genes and chromosome arms. Conclusion: Clinical behavior of relapsed medulloblastoma must be contextualized in terms of up-front therapies and molecular classifications. Group 4 tumors exhibit slower biological progression. Utility of radiation at relapse is dependent on patient age and prior treatments. Degree and patterns of molecular conservation at relapse vary by subgroup. Relapse tissue enables verification of molecular targets and identification of occult secondary malignancies.info:eu-repo/semantics/publishedVersio

Journal of Documentation: A Bibliometrics Analysis (2005-2018)

The purpose of this article was to explore the pattern of publications, using bibliometric analysis, of Journal of Documentation for the period of 2005 to 2018. The results of the study shows that a total of 687 articles were published in the 14 years period from 2005 to 2018, with 71 (10.3%) articles being published the highest total in the year 2018. The study confirmed that the maximum number of articles i.e. 304 (43.9%), were published by single authors, out of which, a large number were on research articles. Out of total number of articles published 228 (33.1%) were 16-20 pages in length. Volume number 74 in 2018 had the highest number of citations with a total of 91 (13.6%). In addition, the study confirmed that the highest number of articles were research articles with a total of 493 (71.7), while others were case studies, conceptual studies, literature reviews, viewpoints and technical papers and short communications, etc