21 research outputs found
PrevalĂȘncia, fatores associados e limitaçÔes relacionados ao problema crĂŽnico de coluna entre adultos e idosos no Brasil
China's âPolitics of Harmonyâ and the Quest for Soft Power in International Politics
This article engages with China's âpolitics of harmonyâ to investigate the dangers and possibilities of soft power as a concept and practice. Chinese sources claim that China will be able to exercise soft power due to its tradition of thinking about harmony. Indeed, the concept of harmony looms large in Chinese soft power campaigns, which differentiate China's own harmonious soft power from the allegedly disharmonious hard power of other great powersâin particular Western powers and Japan. Yet, similarly dichotomizing harmony discourses have been employed precisely in the West and Japan. In all three cases, such harmony discourses set a rhetorical trap, forcing audiences to empathize and identify with the âharmoniousâ self or risk being violently âharmonized.â There is no doubt that the soft power of harmony is coercive. More importantly, the present article argues that it has legitimized and enabled oppressive, homogenizing, and bellicose expansionism and rule in the West and Japan. A similarly structured exercise of soft power may enable violence in and beyond China, too. Ultimately, however, we argue that China's own tradition of thinking about harmony may help us to theorize how soft power might be exercised in less antagonistic and violent ways
Evaluation of potential ecological risk, possible sources and controlling factors of heavy metals in surface sediment of Caohai Wetland, China
Tissue distribution comparison between healthy and fatty liver rats after oral administration of hawthorn leaf extract
Policing for Democracy or Democratically Responsive Policing?:Examining the limits of Externally Driven Police Reform
Assessing urban lifeline systems immediately after seismic disaster based on emergency resilience
Carcass parameters and meat quality of Tibetan sheep and Smallâtailed Han sheep consuming diets of lowâprotein content and different energy yields
Prominin-1 controls stem cell activation by orchestrating ciliary dynamics
Proper temporal and spatial activation of stem cells relies on highly coordinated cell signaling. The primary cilium is the sensory organelle that is responsible for transmitting extracellular signals into a cell. Primary cilium size, architecture, and assembly-disassembly dynamics are under rigid cell cycle-dependent control. Using mouse incisor tooth epithelia as a model, we show that ciliary dynamics in stem cells require the proper functions of a cholesterol-binding membrane glycoprotein, Prominin-1 (Prom1/CD133), which controls sequential recruitment of ciliary membrane components, histone deacetylase, and transcription factors. Nuclear translocation of Prom1 and these molecules is particularly evident in transit amplifying cells, the immediate derivatives of stem cells. The absence of Prom1 impairs ciliary dynamics and abolishes the growth stimulation effects of sonic hedgehog (SHH) treatment, resulting in the disruption of stem cell quiescence maintenance and activation. We propose that Prom1 is a key regulator ensuring appropriate response of stem cells to extracellular signals, with important implications for development, regeneration, and diseases