Análisis descriptivo de buenas prácticas inclusivas de recursos humanos en diversas organizaciones = Descriptive analysis of good inclusive human resources practices in various organizations

43 páginas.Trabajo Fin de Máster en Dirección y Gestión de Personas (Curso 2022-23). Tutor: Dr. D. José Antonio Climent Rodríguez. En esta investigación se plantea un breve análisis de la inclusión laboral sobre distintos escenarios y el impacto que ha tenido este en las relaciones laborales y formas de contratación, partiendo de la base de la dirección y gestión de personas en materia inclusiva, siendo una realidad que cada día se evidencia más en las organizaciones, lo cual permite mejorar las condiciones y calidad de la vida laboral del personal trabajador que repercute directamente en su familia y el entorno social. La intervención realizada fue objeto principal de corroborar los estudios sobre las guías de buenas prácticas inclusivas y analizar de qué manera se ven reflejadas las prácticas laborales inclusivas en las diferentes organizaciones tanto privadas como públicas, reconociendo la importancia de garantizar los derechos y deberes de la inclusión equitativa en las diferentes empresas. De esta manera se realizó un abordaje mediante una revisión bibliográfica de los distintos modos de organización del trabajo, examinando cuestiones vinculadas a los cambios introducidos por la inclusión, la equidad, igualdad y el liderazgo y su influencia y como esto genera consecuencias en el mundo del trabajo. La importancia de la temática está enmarcada en las diferentes situaciones que presentan las personas trabajadoras al momento de observar varias barreras sociales, culturales, políticas, entre otras, que muchas veces dificultan la participación en un ambiente laboral. Finalmente, se concluye que se hace indispensable generar y desarrollar acciones empresariales que contribuyan a la inclusión laboral y aceptar la diversidad como una realidad, la cual no debe de ser un limitante para generar crecimientos que influyan en las relaciones laborales y económicas de las empresas y de carácter individual, como una cultura de inclusión trazando diferentes tipos de incentivos para mejorar la empleabilidad a nivel local, nacional e internacional, por ello, se finiquita con unos elementos y fases principales para la elaboración de una guía de manual de buenas prácticas inclusivas dentro de las organizaciones.This research proposes a brief analysis of labour inclusion on different scenarios and the impact that this has had on labour relations and forms of recruitment, based on the basis of the direction and management of people in inclusive matters, being a reality that is increasingly evident in organisations, which allows improving the conditions and quality of working life of working staff that directly affects their family and social environment. The main purpose of the intervention was to corroborate the studies on the guides to good inclusive practices and to analyse how inclusive labour practices are reflected in the different organisations, both private and public, recognising the importance of guaranteeing the rights and duties of equal inclusion in the different companies. In this way, a bibliographical review of the different ways of organising work was carried out, examining questions linked to the changes introduced by inclusion, equity, equality and leadership and their influence and how this generates consequences in the world of work. The importance of the subject is framed in the different situations that workers present when observing various social, cultural and political barriers, among others, which often hinder participation in a work environment. Finally, it is concluded that it is essential to generate and develop business actions that contribute to labour inclusion and accept diversity as a reality, which should not be a limiting factor to generate growth that influences the labour and economic relations of companies and individuals, as a culture of inclusion tracing different types of incentives to improve employability at local, national and international level, therefore, it ends with some elements and main phases for the development of a manual guide of good inclusive practices within organisations

Evidences for a new role of miR-214 in chondrogenesis

miR-214 is known to play a role in mammalian skeletal development through inhibition of osteogenesis and stimulation of osteoclastogenesis, but data regarding other vertebrates, as well as a possible role in chondrogenesis, remain unknown. Here, we show that miR-214 expression is detected in bone and cartilage of zebrafish skeleton, and is downregulated during murine ATDC5 chondrocyte differentiation. Additionally, we observed a conservation of the transcriptional regulation of miR-214 primary transcript Dnm3os in vertebrates, being regulated by Ets1 in ATDC5 chondrogenic cells. Moreover, overexpression of miR-214 in vitro and in vivo mitigated chondrocyte differentiation probably by targeting activating transcription factor 4 (Atf4). Indeed, miR-214 overexpression in vivo hampered cranial cartilage formation of zebrafish and coincided with downregulation of atf4 and of the key chondrogenic players sox9 and col2a1. We show that miR-214 overexpression exerts a negative role in chondrogenesis by impacting on chondrocyte differentiation possibly through conserved mechanisms.Calouste Gulbenkian Foundation (program "Na Fronteira das Ciencias da Vida"); FCT [UID/Multi/04326/2013, PEst-C/MAR/LA0015/2011, SFRH/BD/38607/2007, SFRH/BPD/45034/2008, SFRH/BPD/111289/2015]; European Commission (ERDF-COMPETE) [PEst-C/MAR/LA0015/2011]info:eu-repo/semantics/publishedVersio

Pulmonary Arteriovenous Malformation can be Associated with Embolic Stroke of Undetermined Source (ESUS)

Pulmonary arteriovenous malformations (PAVMs) are rare vascular anomalies. Alternative designations are pulmonary arteriovenous fistulae or aneurysms. Although mostly asymptomatic, PAVMs can cause respiratory symptoms due to right-to-left shunt. The central nervous system is a potential target for complications, including stroke, as a result of paradoxical embolism. In this report, the authors describe an unusual case of cerebral emboli caused by paradoxical embolism through a PAVM, presenting with a broad pathology including orthodeoxia, central cyanosis and digital clubbing, which should be kept in mind since misdiagnosis may cause severe morbidity in young adults

Tribenuron-methyl metabolism and the rare Pro197Phe double mutation together with 2,4-D metabolism and reduced absorption can evolve in Papaver rhoeas with multiple and cross herbicide resistance to ALS inhibitors and auxin mimics

Multiple resistance mechanisms to ALS inhibitors and auxin mimics in two Papaver rhoeas populations were investigated in wheat fields from Portugal. Dose-response trials, also with malathion (a cytochrome P450 inhibitor), cross-resistance patterns for ALS inhibitors and auxin mimics, alternative herbicides tests, 2,4-D and tribenuron-methyl absorption, translocation and metabolism experiments, together with ALS activity, gene sequencing and enzyme modelling and ligand docking were carried out. Results revealed two different resistant profiles: one population (R1) multiple resistant to tribenuron-methyl and 2,4-D, the second (R2) only resistant to 2,4-D. In R1, several target-site mutations in Pro197 and enhanced metabolism (cytochrome P450-mediated) were responsible of tribenuron-methyl resistance. For 2,4-D, reduced transport was observed in both populations, while cytochrome P450-mediated metabolism was also present in R1 population. Moreover, this is the first P. rhoeas population with enhanced tribenuron-methyl metabolism. This study reports the first case for P. rhoeas of the amino acid substitution Pro197Phe due to a double nucleotide change. This double mutation could cause reduced enzyme sensitivity to most ALS inhibitors according to protein modelling and ligand docking. In addition, this study reports a P. rhoeas population resistant to 2,4-D, apparently, with reduced transport as the sole resistance mechanism.This work has been supported by the Asociacion de Agroquimicos y Medio Ambiente, Spain. Joel Torra acknowledges support from the Spanish Ministry of Science, Innovation, and Universities (grant Ramon y Cajal RYC2018–023866-I) and by the Spanish State Research Agency, Spain (AEI) and the European Regional Development Fund, EU (ERDF) through the projects AGL2017-83325-C4-2-R and PID2020-113229RB- C42. The field surveys made in Portugal were supported by Foundation for Science and Technology through the project UIDB/05064/2020 (VALORIZA). Jorge Lozano-Juste group is funded by grants RYC2020- 029097-I and PID2021-128826OA-I00 from Ministerio de Ciencia e Innovaci ́on (MCIN, Spain), AEI and the ERDF

Limitations to Starch Utilization in Barramundi (Lates calcarifer) as Revealed by NMR-Based Metabolomics

Practical diets for commercial barramundi production rarely contain greater than 10% starch, used mainly as a binding agent during extrusion. Alternative ingredients such as digestible starch have shown some capacity to spare dietary protein catabolism to generate glucose. In the present study, a carnivorous fish species, the Asian seabass (Lates calcarifer) was subjected to two diets with the same digestible energy: Protein (P) – with high protein content (no digestible starch); and Starch (S) – with high digestible (pregelatinized) starch content. The effects of a high starch content diet on hepatic glycogen synthesis as well as the muscle and liver metabolome were studied using a complementary approach of 1H and 2H NMR. The hepatosomatic index was lower for fish fed high starch content diet while the concentration of hepatic glycogen was similar between groups. However, increased glycogen synthesis via the direct pathway was observed in the fish fed high starch content diet which is indicative of increased carbohydrate utilization. Multivariate analysis also showed differences between groups in the metabolome of both tissues. Univariate analysis revealed more variations in liver than in muscle of fish fed high starch content diet. Variations in metabolome were generally in agreement with the increase in the glycogen synthesis through direct pathway, however, this metabolic shift seemed to be insufficient to keep the growth rate as ensured by the diet with high protein content. Although liver glycogen does not make up a substantial quantity of total stored dietary energy in carnivorous fish, it is a key regulatory intermediate in dietary energy utilization

Hallux Limitus Influence on Plantar Pressure Variations during the Gait Cycle: A Case-Control Study

´[Abstract] Background: Hallux limitus is a common foot disorder whose incidence has increased in the school-age population. Hallux limitus is characterized by musculoskeletal alteration that involves the metatarsophalangeal joint causing structural disorders in different anatomical areas of the locomotor system, affecting gait patterns. The aim of this study was to analyze dynamic plantar pressures in a school-aged population both with functional hallux and without. Methods: A full sample of 100 subjects (50 male and 50 female) 7 to 12 years old was included. The subjects were identified in two groups: the case group (50 subjects characterized as having hallux limitus, 22 male and 28 female) and control group (50 subjects characterized as not having hallux limitus, 28 male and 22 female). Measurements were obtained while subjects walked barefoot in a relaxed manner along a baropodometric platform. The hallux limitus test was realized in a seated position to sort subjects out into an established study group. The variables checked in the research were the surface area supported by each lower limb, the maximum peak pressure of each lower limb, the maximum mean pressure of each lower limb, the body weight on the hallux of each foot, the body weight on the first metatarsal head of each foot, the body weight at the second metatarsal head of each foot, the body weight at the third and fourth metatarsal head of each foot, the body weight at the head of the fifth metatarsal of each foot, the body weight at the midfoot of each foot, and the body weight at the heel of each foot. Results: Non-significant results were obtained in the variable of pressure peaks between both study groups; the highest pressures were found in the hallux with a p-value of 0.127 and in the first metatarsal head with a p-value 0.354 in subjects with hallux limitus. A non-significant result with a p-value of 0.156 was obtained at the second metatarsal head in healthy subjects. However, significant results were observed for third and fourth metatarsal head pressure in healthy subjects with a p-value of 0.031 and regarding rearfoot pressure in subjects with functional hallux limitus with a p-value of 0.023. Conclusions: School-age subjects with hallux limitus during gait exhibit more average peak plantar pressure in the heel and less peak average plantar pressure in the third and fourth metatarsal head as compared to healthy children aged between 7 and 12 years old

Measurement of the cross section for the production of a WW boson in association with b−b^- jets in pppp collisions at s=7\sqrt{s}=7 TeV with the ATLAS detector

A measurement is presented of the cross section for the production of a W boson with one or two jets, of which at least one must be a b-jet, in pp collisions at sqrt(s)=7 TeV. Production via top decay is not included in the signal definition. The measurement is based on 35 pb^-1 of data collected with the ATLAS detector at the LHC. The W+b-jet cross section is defined for jets reconstructed with the anti-kt clustering algorithm with transverse momentum above 25 GeV and rapidity within +/-2.1. The b-jets are identified by reconstructing secondary vertices. The fiducial cross section is measured both for the electron and muon decay channel of the W boson and is found to be 10.2 +/- 1.9 (stat) +/- 2.6 (syst) pb for one lepton flavour. The results are compared with next-to-leading order QCD calculations, which predict a cross section smaller than, though consistent with, the measured value.Peer Reviewe

Search for New Physics in the Dijet Mass Distribution using 1 fb−1^{-1} of pppp Collision Data at s=\sqrt{s}=7 TeV collected by the ATLAS Detector

Invariant mass distributions of jet pairs (dijets) produced in LHC proton-proton collisions at a centre-of-mass energy sqrt(s)=7 TeV have been studied using a data set corresponding to an integrated luminosity of 1.0 fb^-1 recorded in 2011 by ATLAS. Dijet masses up to ~4 TeV are observed in the data, and no evidence of resonance production over background is found. Limits are set at 95% CL for several new physics hypotheses: excited quarks are excluded for masses below 2.99 TeV, axigluons are excluded for masses below 3.32 TeV, and colour octet scalar resonances are excluded for masses below 1.92 TeV.Peer Reviewe

Measurement of the top quark pair production cross section in pppp collisions at s=7\sqrt{s}=7 TeV in dilepton final states with ATLAS

A measurement of the production cross section of top quark pairs (ttbar) in proton-proton collisions at a center-of-mass energy of 7 TeV recorded with the ATLAS detector at the Large Hadron Collider is reported. Candidate events are selected in the dilepton topology with large missing transverse energy and at least two jets. Using a data sample corresponding to an integrated luminosity of 35 pb^-1, a ttbar production cross section of 171 +/- 20(stat.) +/- 14(syst.) +8-6(lum.) pb is measured for an assumed top quark mass of 172.5 GeV. A second measurement requiring at least one jet identified as coming from a b quark yields a comparable result, demonstrating that the dilepton final states are consistent with being accompanied by b-quark jets. These measurements are in good agreement with Standard Model predictions.Peer Reviewe

Performance of Missing Transverse Momentum Reconstruction in Proton-Proton Collisions at 7 TeV with ATLAS

The measurement of missing transverse momentum in the ATLAS detector, described in this paper, makes use of the full event reconstruction and a calibration based on reconstructed physics objects. The performance of the missing transverse momentum reconstruction is evaluated using data collected in pp collisions at a centre-of-mass energy of 7 TeV in 2010. Minimum bias events and events with jets of hadrons are used from data samples corresponding to an integrated luminosity of about 0.3 inverse nb and 600 inverse nb, together with events containing a Z boson decaying to two leptons (electrons or muons) or a W boson decaying to a lepton (electron or muon) and a neutrino, from a data sample corresponding to an integrated luminosity of about 36 inverse pb. An estimate of the systematic uncertainty on the missing transverse momentum scale is presented.Peer Reviewe