85 research outputs found

    Metamorfismo y estructura de la Formación Maimón y los Complejos Duarte y Río Verde, Cordillera Central Dominicana: implicaciones en la estructura y la evolución del primitivo Arco Isla Caribeño

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    The mainly metabasaltic pre-Aptian/Albian basement of the Median Belt of Hispaniola includes the Duarte Complex, the Río Verde Complex and the Maimón-Los Ranchos Formations. In base to mineral assemblages present in metabasic rocks and P-T conditions estimated from thermobarometry, the Río Verde Complex is divided into four metamorphic zones and Zone IV is further subdivided into two. The metamorphic grade increase upward in the structural sequence, from prehnite-pumpellyte facies (Zone I), through greens-chist facies (Zones II and III) and amphibolite facies (Zone IVa), to upper amphibolite facies (Zone IVb), only restricted to Cpx-bearing amphibolites just below the contact with the overlying Loma Caribe Peridotite. The metamorphic field gradient is inverse and of low-P type. The P-T paths documented for Zones IVa and IVb of the Río Verde Complex involve a two-stage prograde evolution: a first event of near isobaric heating in the low-pressure field, typical of sub-ophiolite metamorphic sole rocks and characterized by critical high-grade assemblages; and a second event marked by a medium-pressure overprint of the first-stage metamorphic assemblages following a high-P gradient. These P-T paths are interpreted to result from intra-oceanic thrusting during the closure of a back-arc basin related with the Primitive Caribbean Island Arc and the onset of subduction of arc units in the Aptian/Albian time, which formed the high-pressure metamorphic overprint. The heating and development of an inverted metamorphic gradient in the sub-ophiolite Río Verde Complex, can be genetically related with the hanginwall emplacement of the hot peridotitic slice and the conductive heat transfer downward. The studied sector of the Duarte Complex (metamorphosed oceanic plateau) is divided into three metamorphic zones. Their distribution suggest that there is a temperature increase westward and downward in the structural sequence, from the upper greenschist facies (zone A), through Ep-amphibolite and amphibolite facies (zone B), to upper amphibolite transitional to lower granulite facies (zone C). The metamorphic field gradient is normal and the mid-P type (25-30º C/km). The lowest structural levels of the complex are occupied by the gabro-norites of the La Jautía batholith, which formed in ductile shear zones Grt+Opx-bearing granulites metamorphic assemblages. The 89 Ma date obtained from foliated tonalites (U-Pb in zircons) established an Upper Cretaceous age for the main ductile shearing deformation. However, the deformation is very heterogeneous in the complex, existing regionally wide metamorphic sectors without related foliation development. Therefore, the prograde metamorphism of the Duarte Complex is interpreted to result from moderated thickening of a previously thick oceanic crust, due to the great accumulation of plateau-basalts (30 km). The post-thermal peak P-T paths suggest the unloading and cooling of the complex, during the continuous retrograde development of deformative and mylonitic non-coaxial Sp fabrics (84,6±0,5 Ma; 40 Ar/39 Ar cooling age in syn-Sp muscovite). In summary, the metamorphic rocks of the pre-Aptian/Albian basement units of the Median Belt record different stages in the history of the acretion-obduction of the Duarte plateau with the Caribbean Primitive Island Arc. All these tectonothermal events pre-date the final arc-continent collision between the Caribbean island arc and the Bahamas platform during the Late Cretaceous

    Subdivisión geoquímica del Arco Isla Circum-Caribeño, Cordillera Central Dominicana: Implicaciones para la formación, acrecion y crecimineto cortical en un ambiente intraoceánico

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    The Upper Cretaceous-Eocene Circum-Caribbean island-arc system (AICC) is a complex collage of crustal units or terranes s.l. which have formed and accreted within an intra-oceanic environment since Late Jurassic-Early Cretaceous times. In the Cordillera Central of the Dominican Republic these terranes are represented by several tectonostratigraphic units, that define a pre-Aptian-Albian deformed and metamorphosed basement, over and into which the igneous rocks of the AICC were extruded or intruded. Basement sequences can be subdivided into: (1) a plume-related Duarte terrane (plateau I); (2) a primitive arc-related Maimón-Amina terrane, which includes intra- or back-arc N-MORB units (Río Verde Complex) with a subduction geochemical imprint; and (3) the Loma Caribe peridotite terrane of mantle provenance. Two successive stages of the arc growth are superposed: an Early Cretaceous arc tholeiite stage with boninitic affinities (arc I), and a Late Cretaceous-Eocene calc-alkaline stage (AICC; arc II). The arc I stage is not recorded in the Duarte terrane but is represented in the Maimón-Amina terrane by the Río Verde Complex, the Maimón Forma-tion and the Peralvillo Norte Formation. In the Duarte terrane, the arc II growth stage include the Siete Cabezas Formation (Cenomanian- Maastrichtian, plateau II) and the fill of an intra-arc basin by the Tireo Formation (Cenomanian-Maastrichtian). In the Maimón-Amina terrane, the arc II growth is represented by the Las Lagunas and Peralvillo Sur Formations. The former lies unconformably on rudist-bearing limestone of Albian age (Hatillo Limestone). The Jautía gabbro-norite batholith and the calc-alkaline foliated and non-foliated tonalitic plutons of Late-Cretaceous-Early Eocene age intrude the rocks of the Duarte terrane except the Siete Cabezas Formation. Deformation and metamorphism of the pre-Aptian-Albian basement is a consequence of the collision of the Duarte plateau terrane with the Caribbean primitive island arc (Maimón-Amina terrane), that caused the emplacement of the Duarte terrane with a fragment of oceanic lithosphere (ophiolite). The interpretation of the geological and geochemical data support a tectonomagmatic model, which relates the compositional evolution of the intruded and extruded magmas in this segment of the AICC, with a flip in the subduction polarity under the primitive arc after the Aptian/Albian collision

    Documento de consenso sobre el tratamiento antimicrobiano de las infecciones bacterianas odontogénicas

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    Las infecciones de la cavidad bucal son un problema de salud pública frecuente y motivo constante de prescripción antibiótica; el 10% de los antibióticos se emplean para tratar este problema. Sin embargo, hasta la fecha son pocos los estudios realizados para determinar su incidencia. Asímismo, su relación con ciertas enfermedades sistémicas (cardiacas, endocrinas, etc...) confiere a estas patologías una importancia vital. A pesar de la reconocida frecuencia e importancia de las infecciones odontogénicas, llama la atención la actual dispersión de criterio en varios aspectos referentes a su clasificación, terminología y recomendaciones terapéuticas. El objetivo principal de este documento, realizado con el consenso de especialistas en microbiología y odontología, es establecer unas recomendaciones útiles para todos los profesionales implicados en el manejo clínico de estas patologías. Recibe especial atención el aumento de la prevalencia de resistencias bacterianas observado durante los últimos años y, en concreto, la proliferación de cepas productoras de betalactamasas. Otro factor causal importante de la aparición de resistencias es la falta de cumplimiento terapéutico, en especial en lo que respecta a la dosis y a la duración del tratamiento. Así pues, estas patologías constituyen un problema complejo cuyo abordaje requiere la instauración de antimicrobianos de amplio espectro, con adecuados parámetros farmacocinéticos, con buena tolerancia y una posología cómoda que permita que el paciente reciba la dosis adecuada durante el tiempo necesario. Amoxicilina/ácido clavulánico a dosis altas (2000mg/ 125mg) ha demostrado buenos resultados y capacidad para superar resistencias. Otros agentes como metronidazol y clindamicina, seguidos de claritromicina y azitromicina han demostrado también ser activos frente a la mayoría de los microorganismos responsables de las infecciones odontogé[email protected]

    Low-diffusion Xe-He gas mixtures for rare-event detection: electroluminescence yield

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    High pressure xenon Time Projection Chambers (TPC) based on secondary scintillation (electroluminescence) signal amplification are being proposed for rare event detection such as directional dark matter, double electron capture and double beta decay detection. The discrimination of the rare event through the topological signature of primary ionisation trails is a major asset for this type of TPC when compared to single liquid or double-phase TPCs, limited mainly by the high electron diffusion in pure xenon. Helium admixtures with xenon can be an attractive solution to reduce the electron diffu- sion significantly, improving the discrimination efficiency of these optical TPCs. We have measured the electroluminescence (EL) yield of Xe–He mixtures, in the range of 0 to 30% He and demonstrated the small impact on the EL yield of the addition of helium to pure xenon. For a typical reduced electric field of 2.5 kV/cm/bar in the EL region, the EL yield is lowered by ∼ 2%, 3%, 6% and 10% for 10%, 15%, 20% and 30% of helium concentration, respectively. This decrease is less than what has been obtained from the most recent simulation framework in the literature. The impact of the addition of helium on EL statistical fluctuations is negligible, within the experimental uncertainties. The present results are an important benchmark for the simulation tools to be applied to future optical TPCs based on Xe-He mixtures. [Figure not available: see fulltext.]

    Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

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    Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components. Dendritic cells (DCs) play a key role in the defense against viral infections, for instance plasmacytoid DCs (pDCs), have the capacity to produce vast amounts of interferon-alpha (IFN-α). In COVID-19 there is a deficit in DC numbers and IFN-α production, which has been associated with disease severity. In this work, we described that in addition to the DC deficiency, several DC activation and homing markers were altered in acute COVID-19 patients, which were associated with multiple inflammatory markers. Remarkably, previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+ myeloid DCs and pDCs seven months after SARS-CoV-2 infection. Moreover, the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients, while no restoration of integrin β7 and indoleamine 2,3-dyoxigenase (IDO) levels were observed. These findings contribute to a better understanding of the immunological sequelae of COVID-19

    Results of the material screening program of the NEXT experiment

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    [EN] The Neutrino Experiment with a Xenon TPC (NEXT), intended to investigate neutrinoless double beta decay, requires extremely low background levels. An extensive material screening and selection process to assess the radioactivity of components is underway combining several techniques, including germanium γ-ray spectrometry performed at the Canfranc Underground Laboratory; recent results of this material screening program are presented here.Dafni, T.; Álvarez-Puerta, V.; Bandac, I.; Bettini, A.; Borges, FIGM.; Camargo, M.; Carcel, S.... (2016). Results of the material screening program of the NEXT experiment. Nuclear and Particle Physics Proceedings. 273-275:2666-2668. https://doi.org/10.1016/j.nuclphysbps.2015.10.024S26662668273-27
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