979 research outputs found

    Evaluación del micelio (Aspergillus niger) en combinación con el pasto elefante (Pennisetum purpureum), como alimento para novillas Holstein.

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    El experimento pretendió evaluar tres niveles de micelio en las dietas de novillas Holstein en crecimiento y determinar el efecto sobre el consumo de pasto elefante combinado con cantidades controladas de micelio. El experimento se condujo durante 175 días, se diseñó en bloques completamente al azar con cuatro tratamiento y 2 repeticiones. Los tratamiento resultaron de los niveles de combianción de pasto elefante y micelio: 100 por ciento+0 por ciento=T1, T2=88 por ciento+12 por ciento, T3=76 por ciento+24 por ciento, T4=64 por ciento+36 por ciento. Se utilizaron 32 novillas Holstein con un peso promedio 210 kg. El micelio tuvo gran aceptación por las novillas y su consumo no produjo efecto negativo aparente en los animales a medida que ingerían crecientes niveles de micelio. Hubo diferencias significativas entre (P menor o igual que 0.05) T1 y T2, T3 y T4 pero no entre T2, T3, T4. Aunque el conteniod de fibra del micelio (52 por ciento) es mayor que el del pasto (30 por ciento) por los resultados positivos mostrados por animales que recibieron micelio, se deduce que hay diferencia entre los tipos de fibra. Sugiriendo que es más digestible que la del pasto elefante o que el micelio estimula la fermentación rumina

    Sustained efficacy and detailed clinical follow-up of first-line ibrutinib treatment in older patients with chronic lymphocytic leukemia: extended phase 3 results from RESONATE-2.

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    Results of RESONATE-2 (PCYC-1115/1116) supported approval of ibrutinib for first-line treatment of chronic lymphocytic leukemia. Extended analysis of RESONATE-2 was conducted to determine long-term efficacy and safety of ibrutinib in older patients with chronic lymphocytic leukemia. A total of 269 patients aged ≥65 years with previously untreated chronic lymphocytic leukemia without del(17p) were randomized 1:1 to ibrutinib (n=136) or chlorambucil (n=133) on days 1 and 15 of a 28-day cycle for 12 cycles. Median ibrutinib treatment duration was 28.5 months. Ibrutinib significantly prolonged progression-free survival versus chlorambucil (median, not reached vs 15 months; hazard ratio, 0.12; 95% confidence interval, 0.07-0.20; P<0.0001). The 24-month progression-free survival was 89% with ibrutinib (97% and 89% in patients with del[11q] and unmutated immunoglobulin heavy chain variable region gene, respectively). Progression-free survival rates at 24 months were also similar regardless of age (<75 years [88%], ≥75 years [89%]). Overall response rate was 92% (125/136). Rate of complete response increased substantially from 7% at 12 months to 18% with extended follow up. Greater quality of life improvements occurred with ibrutinib versus chlorambucil in Functional Assessment of Chronic Illness Therapy-Fatigue (P=0.0013). The most frequent grade ≥3 adverse events were neutropenia (12%), anemia (7%), and hypertension (5%). Rate of discontinuations due to adverse events was 12%. Results demonstrated that first-line ibrutinib for elderly patients with chronic lymphocytic leukemia provides sustained response and progression-free survival benefits over chemotherapy, with depth of response improving over time without new toxicity concerns. This trial was registered at clinicaltrials.gov identifier 01722487 and 01724346

    Precision Measurement of the Beam-Normal Single-Spin Asymmetry in Forward-Angle Elastic Electron-Proton Scattering

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    A beam-normal single-spin asymmetry generated in the scattering of transversely polarized electrons from unpolarized nucleons is an observable related to the imaginary part of the two-photon exchange process. We report a 2% precision measurement of the beam-normal single-spin asymmetry in elastic electron-proton scattering with a mean scattering angle of theta_lab = 7.9 degrees and a mean energy of 1.149 GeV. The asymmetry result is B_n = -5.194 +- 0.067 (stat) +- 0.082 (syst) ppm. This is the most precise measurement of this quantity available to date and therefore provides a stringent test of two-photon exchange models at far-forward scattering angles (theta_lab -\u3e 0) where they should be most reliable

    Search for R-parity violating supersymmetry via the LLE couplings lambda_{121}, lambda_{122} or lambda_{133} in ppbar collisions at sqrt(s)=1.96 TeV

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    A search for gaugino pair production with a trilepton signature in the framework of R-parity violating supersymmetry via the couplings lambda_121, lambda_122, or lambda_133 is presented. The data, corresponding to an integrated luminosity of L~360/pb, were collected from April 2002 to August 2004 with the D0 detector at the Fermilab Tevatron Collider, at a center-of-mass energy of sqrt(s)=1.96 TeV. This analysis considers final states with three charged leptons with the flavor combinations eel, mumul, and eetau (l=e or mu). No evidence for supersymmetry is found and limits at the 95% confidence level are set on the gaugino pair production cross section and lower bounds on the masses of the lightest neutralino and chargino are derived in two supersymmetric models.Comment: 9 pages, 4 figures (fig2 includes 3 subfigures

    Search for new fermions ("quirks") at the Fermilab Tevatron Collider

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    We report results of a search for particles with anomalously high ionization in events with a high transverse energy jet and large missing transverse energy in 2.42.4 fb1^{-1} of integrated luminosity collected by the D0 experiment at the Fermilab Tevatron ppˉp\bar{p} collider. Production of such particles (quirks) is expected in scenarios with extra QCD-like {\it SU(N)} sectors, and this study is the first dedicated search for such signatures. We find no evidence of a signal and set a lower mass limit of 107 ~GeV for the mass of a charged quirk with strong dynamics scale Λ\Lambda in the range from 10 keV to 1 MeV.Comment: submitted to Phys. Rev. Letter

    Measurements of differential cross sections of Z/gamma*+jets+X events in proton anti-proton collisions at sqrt{s}=1.96 TeV

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    We present cross section measurements for Z/gamma*+jets+X production, differential in the transverse momenta of the three leading jets. The data sample was collected with the D0 detector at the Fermilab Tevatron proton anti-proton collider at a center-of-mass energy of 1.96 TeV and corresponds to an integrated luminosity of 1 fb-1. Leading and next-to-leading order perturbative QCD predictions are compared with the measurements, and agreement is found within the theoretical and experimental uncertainties. We also make comparisons with the predictions of four event generators. Two parton-shower-based generators show significant shape and normalization differences with respect to the data. In contrast, two generators combining tree-level matrix elements with a parton shower give a reasonable description of the the shapes observed in data, but the predicted normalizations show significant differences with respect to the data, reflecting large scale uncertainties. For specific choices of scales, the normalizations for either generator can be made to agree with the measurements.Comment: Published in PLB. 11 pages, 3 figure

    Measurement of the Bs0B^{0}_{s} Lifetime Using Semileptonic Decays

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    We report a measurement of the Bs0B^0_{s} lifetime in the semileptonic decay channel Bs0Dsμ+νXB^0_{s}\to D^-_s \mu^{+}\nu X (and its charge conjugate), using approximately 0.4 fb1^{-1} of data collected with the D0 detector during 2002 -- 2004. We have reconstructed 5176 Dsμ+D^-_s \mu^{+} signal events, where the DsD_s^- is identified via the decay DsϕπD_s^-\to \phi\pi^-, followed by ϕK+K\phi\to K^+ K^-. Using these events, we have measured the Bs0B^0_s lifetime to be τ(Bs0)=1.398±0.044\tau(B^0_{s}) = 1.398 \pm 0.044 (stat)0.025+0.028({stat}) ^{+0.028}_{-0.025} (syst)ps({syst}) {ps}. This is the most precise measurement of the Bs0B_s^0 lifetime to date.Comment: To appear in Phys. Rev. Lett., 7 pages, 2 figure

    A measurement of the W boson mass using large rapidity electrons

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    We present a measurement of the W boson mass using data collected by the D0 experiment at the Fermilab Tevatron during 1994--1995. We identify W bosons by their decays to e-nu final states where the electron is detected in a forward calorimeter. We extract the W boson mass, Mw, by fitting the transverse mass and transverse electron and neutrino momentum spectra from a sample of 11,089 W -> e nu decay candidates. We use a sample of 1,687 dielectron events, mostly due to Z -> ee decays, to constrain our model of the detector response. Using the forward calorimeter data, we measure Mw = 80.691 +- 0.227 GeV. Combining the forward calorimeter measurements with our previously published central calorimeter results, we obtain Mw = 80.482 +- 0.091 GeV
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