Fundamental analysis Peruvian non listed company - Real Pharma

The present case study seeks to guide the potential investor through the process of analyzing the financial situation of a company to be able to make an adequate deal for an acquisition or invest. The case intends to follow a top-down analysis structure as follows: a macroeconomic analysis, which covers the gross domestic product, inflation and others; followed by a sectorial study, which comprises the study of competitors, suppliers, clients, and others; and the company?s analysis both from a financial and non-financial perspective.El presente estudio de caso busca guiar al inversionista potencial a trav?s del proceso de an?lisis de la situaci?n financiera de una empresa para poder hacer un trato adecuado para una adquisici?n o inversi?n. El caso pretende seguir una estructura de an?lisis descendente de la siguiente manera: un an?lisis macroecon?mico, que cubre el producto interno bruto, la inflaci?n y otros; seguido de un estudio sectorial, que comprende el estudio de competidores, proveedores, clientes y otros; y el an?lisis de la compa??a tanto desde una perspectiva financiera como no financiera

Estructura de costos de producción para sistemas agropecuarios en el Piedemonte del Meta

La Oficina de Planeación de Corpoica Regional Ocho, con el ánimo de brindar una herramienta más para la planificación y toma de decisiones, tanto para el agricultor, como para el asistente técnico, investigador, planificador y demás participantes involucrados en el proceso de producción y ejecución de proyectos agropecuarios, pone a disposición la siguiente estructura de costos, cuya información muestra los requerimientos mínimos y el costo promedio de insumos y mano de obra que demanda cada una de las actividades en los principales sistemas de producción agropecuarios, fundamentalmente del Piedemonte del departamento del Meta y que puede ser adoptada en otras regiones de la Orinoquia colombiana

Mobile Personal Health Monitoring for Automated Classification of Electrocardiogram Signals in Elderly

Mobile electrocardiogram (ECG) monitoring is an emerging area that has received increasing attention in recent years, but still real-life validation for elderly residing in low and middle-income countries is scarce. We developed a wearable ECG monitor that is integrated with a self-designed wireless sensor for ECG signal acquisition. It is used with a native purposely designed smartphone application, based on machine learning techniques, for automated classification of captured ECG beats from aged people. When tested on 100 older adults, the monitoring system discriminated normal and abnormal ECG signals with a high degree of accuracy (97%), sensitivity (100%), and specificity (96.6%). With further verification, the system could be useful for detecting cardiac abnormalities in the home environment and contribute to prevention, early diagnosis, and effective treatment of cardiovascular diseases, while keeping costs down and increasing access to healthcare services for older persons

The Urban Resilience of Monastic Architecture and the Heritage Management: The Case of Seville’s Saint Augustin Convent

AIP Conference Proceedings, Volume 2574, Issue 1The aim of this communication is to develop how to preserve the permanencies and losses of old convents and monasteries after urban transformations, as well as to review the instruments of heritage protection that have failed. It is a common process that has been experimented in many European cities and whose protagonist are the cloistered convents. Pieces that have served to make city and help to build its periphery. But, with the passage of time they were submerged in abandonment, fragmentation, forgetfulness and even loss their memory. This situation remains until a fresh impulse transforms it into a new object of patrimonial value, resource for tourist use, and rejoints the city. The methodology followed is based on the simultaneous use of different 2D and 3D assisted drawing tools, always supported by historical cartography and written documentary sources. In Spain, the city of Seville stands out as one of the settings for the development of religious orders, more than one hundred. As a result of historical events and developments, many of Seville's convents and monasteries have disappeared completely. The number of monasteries that have remained intact, preserving their use value as a religious institution are very small, only 15. However, it is common to find remnants in the present-day city where their remains are still visible. Saint Augustin monastery was founded in the 13th century outside the city walls, 15,016 m2 next to the Carmona Gate. Its location was bounded by the city and the city walls to the west, the aqueduct to the south and the Tagarete River to the east. Both the aqueduct and the river allowed for the location of the building as well as the extensive development of its orchards. The importance of water in the conventual space is due to the need for irrigation and cultivation of the green area. In 1835, the convent was disentailed, and the building was divided up. New dwellings were also built on the site of the former convent, which was in a privileged location. New streets appeared, the site was completely divided and cloisters, parts of the old convent and its church disappeared. The remains of the building have not been adequately protected for decades. The convent of Saint Augustin is an outstanding example of urban resilience, how a building of great importance and size has managed to survive. Some valuable spaces of the original building are still preserved, such as the refectory, the staircase, and the main cloister. The understanding and protection of Seville's convent heritage requires specific planning tools to address the urban condition of the convents. In addition, their determining role in the morphological construction of the city and the configuration of the historic urban landscape will be stablished. Unpublished material of the urban and architectural research process will be provided under a methodological approach of renewed heritage management, clearly useful for European historic cities

Microstructural and electrochemical analysis of Sb2O5 doped-Ti/RuO2-ZrO2 to yield active chlorine species for ciprofloxacin degradation

ABSTRACT: A Sb2O5 doped-Ti/RuO2-ZrO2 (Ti/SbRuZr) electrode is used to perform the abatement of ciprofloxacin (CIP, C17H18FN3O3). The catalyst was prepared using the Pechini method, and subsequently characterized by XRD, SEM-EDS, EIS and CV. The microstructural analysis of Ti/SbRuZr shows the formation of RuO2 (P42/mnm) and ZrO2 (P2/m) crystalline phases, with an average crystallite size about twice (61.2 nm) lower than Ti/RuO2 (109 nm). Additionally, SEM micrographs reveal that ZrO2 affects the morphological features of the deposited RuO2 layer, turning it into a more heterogeneous material. The electrode capacity was evaluated through the elimination of antibiotic activity (AA) of CIP, revealing that 83 and 45% of AA was removed using Ti/SbRuZr and Ti/RuO2, respectively at 0.19 A h L−1. According to CV analysis, the electrochemical mechanism for CIP degradation was found to proceed through active chlorine species (Cl2-active) on Ti/SbRuZr. This facile kinetics occurring on the ternary catalyst resulted from a high charge transfer resistance for oxygen evolution reaction, as revealed by EIS analysis. HPLC, HPLC-MS, and density functional theory were employed to propose a reaction pathway for CIP degradation. Findings from this work stands out prospective applications of anodic electrochemical oxidation to efficiently eliminate CIP, and the associated proliferation of antibiotic resistant microorganisms in aqueous media

Effect of Cultivar Resistance and Soil Management on Spatial–Temporal Development of Verticillium Wilt of Olive: A Long-Term Study

Verticillium wilt, caused by Verticillium dahliae, challenges olive cultivation and an Integrated Disease Management (IDM) approach is the best-suited tool to combat it. Since 1998, an IDM strategy in an orchard (called Granon, Spain) of the susceptible cv. Picual was conducted by increasing planting density with moderately resistant cv. Frantoio, chemical weed control, and replanting of dead olives with cv. Frantoio following soil solarization. The Verticillium wilt epidemic in Granon orchard was compared to the epidemic in a non-IDM orchard (called Ancla, Spain) with plowed soil and dead Picual olives replanted with the same cultivar. Field evaluations (2012–2013) showed an incidence and severity of the disease as Picual–Ancla > Picual–Granon > Frantoio–Granon. The spatiotemporal dynamics of the Verticillium epidemics from 1998 to 2010 were monitored with digital images using SIG. The annual tree mortalities were 5.6% for Picual olives in Ancla orchard, and 3.1 and 0.7% for Picual and Frantoio olives in Granon orchard, respectively. There was a negative relationship between the mortality of olive trees (%) by the pathogen and the height (m) above sea level. The annual mortality of cv. Picual olives was positively correlated with spring rainfalls. The Index of Dispersion and beta-binomial distribution showed aggregation of Verticillium-dead olives. In conclusion, this IDM strategy considerably reduced the disease in comparison with traditional agronomic practices

Ensinar e aprender português: a digital resource for learning to read and write

In Education, the use of technological resources to support students' teaching and learning is becoming more and more urgent. Teaching and Learning Portuguese [Ensinar e Aprender Português – EAP] is a structured and innovative educational resource, supported by the use of Information and Communication Technologies and based on scientific evidence. It is aimed at students (and teachers) of the four years of primary school. It aims to: i) support the teaching/learning of reading and writing in primary school; ii) signalize, in a timely manner, students at-risk of presenting difficulties in learning to read and write; and iii) support the recovery of learning. This paper will present this digital resource developed for the Portuguese context, based on the Portuguese curriculum and the legislation on inclusive education. It is also anchored in the multilevel approach whose focus on digital transition, on screening tests and monitoring of learning has introduced new challenges in the education system. As it is a digital resource whose activities are self-executable and for which explanatory and corrective feedbacks are provided, it contributes to bridge a gap in terms of digital transition which was particularly visible in a pandemic context such as the one we are going through.In Education, the use of technological resources to support students' teaching and learning is becoming more and more urgent. Teaching and Learning Portuguese [Ensinar e Aprender Português – EAP] is a structured and innovative educational resource, supported by the use of Information and Communication Technologies and based on scientific evidence. It is aimed at students (and teachers) of the four years of primary school. It aims to: i) support the teaching/learning of reading and writing in primary school; ii) signalize, in a timely manner, students at-risk of presenting difficulties in learning to read and write; and iii) support the recovery of learning. This paper will present this digital resource developed for the Portuguese context, based on the Portuguese curriculum and the legislation on inclusive education. It is also anchored in the multilevel approach whose focus on digital transition, on screening tests and monitoring of learning has introduced new challenges in the education system. As it is a digital resource whose activities are self-executable and for which explanatory and corrective feedbacks are provided, it contributes to bridge a gap in terms of digital transition which was particularly visible in a pandemic context such as the one we are going through.This work was financially supported by Portuguese national funds through the FCT (Foundation for Science and Technology) within the framework of the CIEC (Research Center for Child Studies of the University of Minho) projects under the references UIDB/00317/2020 and UIDP/00317/2020

La imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia. Ciudad de Bogotá y municipio de Mosquera, Cundinamarca.

Los escenarios de violencia se presentan sobre todo el territorio colombiano, han dejado afectaciones físicas y psicológicas en las víctimas, por lo cual, en el desarrollo del presente trabajo, se identificará eventos psicosociales desde un enfoque narrativo los cuales permiten potencializar recursos basados desde las experiencias vividas, se inicia con la contextualización análisis realizado desde la narrativa a un cortometraje Capítulo 5, Comisión de la verdad donde se evidencia el caso Nelson, de acuerdo con los hechos contados por el protagonista, se diseñaran preguntas reflexivas, circulares y estratégicas, que permiten realizar una reflexión y una movilización de Nelson y su familia; de igual manera se hará el análisis sobre el video que narra la “masacre de El Salado ocurrida en el año 2000, en departamento de Bolívar” (El Tiempo Casa Editorial, 2020, 11 de febrero), por lo cual, se proponen tres estrategias de abordaje psicosocial, que permitirán realizar la reflexión, la resignificación y la construcción de nuevas narrativas más empoderadas, conllevando a contribuir al bienestar psicológico y social de las víctimas; también se desarrolla el análisis del ejercicio de foto voz que logra visibilizar las experiencias, emociones y perspectivas de las personas afectadas por la violencia, junto con link del video el cual muestra los aportes significativos de la experiencia obtenida por cada uno de los integrantes. Finalmente, se hallan las conclusiones de las actividades realizadas, soportando el abordaje en las víctimas desde los enfoques narrativos.The scenarios of violence are presented throughout the Colombian territory, they have left physical and psychological affectations in the victims, for which, in the development of the present work, psychosocial events will be identified from a narrative approach which allow potentiating resources based on experiences. lived, begins with the contextualization analysis carried out from the narrative to a short film Chapter 5, Truth Commission where the Nelson case is evidenced, according to the facts recounted by the protagonist, reflective, circular and strategic questions will be designed, which allow make a reflection and a mobilization of Nelson and his family; In the same way, the analysis will be made on the video that narrates the "massacre of El Salado that occurred in the year 2000, in the department of Bolívar" (El Tiempo Casa Editorial, 2020, February 11), for which three strategies are proposed. of a psychosocial approach, which will allow reflection, resignification and the construction of new, more empowered narratives, leading to contributing to the psychological and social well-being of the victims; The analysis of the photovoice exercise that manages to make visible the experiences, emotions and perspectives of people affected by violence is also developed, along with a link to the video which shows the significant contributions of the experience obtained by each of the members. Finally, there are the conclusions of the activities carried out, supporting the approach to the victims from the narrative approaches

Architectural and intangible heritage in Andalusia: the impact of tourism after UNESCO’s inscriptions

Póster presentado en la muestra de la International Union of Architects (UIA), la UIA International Forum 2019, con sede en Bakú, bajo la temática ‘Turismo masivo en ciudades históricas'. El Consejo Superior de los Colegios de Arquitectos de España (CSCAE) seleccionó a partir de las propuestas de los Colegios de Arquitectos 6 paneles con los que participó en la exposición. Este panel ha sido desarrollado por miembros del grupo de investigación HUM700: Patrimonio y Desarrollo Urbano Territorial en Andalucía de la Universidad de Sevilla y coordinado por el catedrático y colegiado del COAS Eduardo Mosquera Adell.Poster presented at the exhibition of the International Union of Architects (UIA), the UIA International Forum 2019 in Baku, under the theme ‘Mass tourism in historical cities'. The Superior Council of the Colleges of Architects of Spain (CSCAE) selected 6 panels from the proposals of the Association of Architects. This panel has been developed by members of the Research Lab HUM700: Heritage and Urban Territorial Development in Andalusia at the University of Seville and coordinated by the professor and registered architect Eduardo Mosquera Adell.Colegio Oficial de Arquitectos de SevillaConsejo Andaluz de Colegios Oficiales de ArquitectosConsejo Superior de los Colegios de Arquitectos de Españ