207 research outputs found
An analysis of twitter as a relevant human mobility proxy A comparative approach in spain during the COVID-19 pandemic
During the last years, the analysis of spatio-temporal data extracted from Online Social Networks (OSNs) has become a prominent course of action within the human-mobility mining discipline. Due to the noisy and sparse nature of these data, an important effort has been done on validating these platforms as suitable mobility proxies. However, such a validation has been usually based on the computation of certain features from the raw spatio-temporal trajectories extracted from OSN documents. Hence, there is a scarcity of validation studies that evaluate whether geo-tagged OSN data are able to measure the evolution of the mobility in a region at multiple spatial scales. For that reason, this work proposes a comprehensive comparison of a nation-scale Twitter (TWT) dataset and an official mobility survey from the Spanish National Institute of Statistics. The target time period covers a three-month interval during which Spain was heavily affected by the COVID-19 pandemic. Both feeds have been compared in this context by considering different mobility-related features and spatial scales. The results show that TWT could capture only a limited number features of the latent mobility behaviour of Spain during the study period
CARACTERIZACIÓN DEL VIÑEDO MEDIANTE ANÁLISIS DE DATOS LIDAR AEROTRANSPORTADO
Los últimos vuelos LIDAR (Light Detection and Ranging) realizados a nivel nacional dentro del Plan PNOA, hacen posible el uso de datos LIDAR de gran densidad y mucha precisión sobre gran parte del territorio nacional. Además, a nivel autonómico, algunas comunidades disponen de vuelos de muy alta resolución. Todo ello, abre un abanico interesante de posibilidades de análisis del territorio en base a la generación automática de MDS (modelos digitales de superficie). En este estudio, se pretende utilizar los puntos LIDAR disponibles de mayor resolución para caracterizar los viñedos de una zona vitícola típica en la Cominidad Autónoma de La Rioja y detectar sobre ellos patrones típicos de las distintas formaciones de viñedo (emparrados, formación en vaso, marcos de plantación,...), así como otros parámetros importantes en la gestión de dicho viñedo, como el crecimiento de la masa vegetal, la evolución del color, estudio de marras, etc.En este trabajo, se pretenden fijar los materiales y los procedimientos necesarios para lograr los objetivos propuestos de una forma lo más automática posible. Al mismo tiempo se detectarán y describirán otros posibles usos de la metodología
Velocidad al comer en personas con normopeso y sobrepeso-obesidad: un análisis experimental
La obesidad se ha posicionado como uno de los principales problemas de salud pública en México. Su estudio involucra el análisis de la conducta alimentaria (CA) y de algunos de sus parámetros, como la velocidad al comer (VC). El objetivo de este trabajo fue comparar la VC, tamaño y número de mordiscos, número y patrón de masticaciones que realizan personas con normopeso (n = 5) y sobrepeso-obesidad (n = 4). Mediante un diseño cuasiexperimental de una sola evaluación, los participantes fueron video-grabados mientras comían una rebana de pizza (90 gramos). Se encontraron diferencias significativas en el tamaño del mordisco (Z = 2.357, p = 0.016) y el número de mordiscos (Z = -2.357, p = 0.016), con un tamaño del efecto pequeño en ambos parámetros (r = 0.29), lo que indica que las personas con sobrepeso-obesidad tienen un mordisco de mayor tamaño y realizan un menor número de mordiscos. México posee un ambiente obesogénico y una prevalencia alta en enfermedades crónico-degenerativas, que comparten a la CA como una de las principales causas de su génesis, continuar con el estudio de la VC y parámetros asociados permitirá sentar las bases para el diseño de intervenciones para la prevención de sobrepeso-obesidad
Superficial radiotherapy as haemostatic treatment in breast cancer
Poster Session [EP-1661]
Purpose or Objective Breast cancer is a common pathology in which o = 25% in tumor size and absence of bleeding was observed. Conclusion Surface radiotherapy is a treatment modality that should be taken into account in patients with breast cancer who present bleeding as a consequence of local tumor growth, given that this is a treatment comfortable for the patient, non invasive and increases the quality of patient’s life
Challenges to managing ecosystems sustainably for poverty alleviation: securing well-being in the Andes/Amazon: final report
Chemo-sensory approach for the identification of chemical compounds driving green character in red wines
The present work seeks to define the “green character” of red wines and characterise the groups of molecules potentially involved in that perception. Fifty-four wines were screened by wine experts for different levels of green character. Six different phenolic fractions were obtained by liquid chromatography (LC) and further submitted to sensory and chemical characterisation. The volatile fraction was screened by semipreparative LC, Gas Chromatography-Olfactometry (GC-O) and quantitative analysis. The green character was linked to vegetal aroma, astringency, green and dry tannins according to experts of the Somontano region. Non-volatile fractions containing tannins with mean degree of polymerisation of ten and smaller anthocyanin-derivative pigments (<tetramers) imparted astringency-related sensations such as dryness and stickiness, respectively. No specific aroma compounds were identified in the GC-O study of green wines, however the wines contained significantly higher levels of fusel alcohols. The interaction between isoamyl alcohol and the anthocyanin-derivative fraction and/or tannins is suggested to be involved in the formation of green character in red wines
Abnormal sympathoadrenal development and systemic hypotension in PHD3<sup>–/–</sup> mice.
Fortalecimiento de capacidades locales para mejorar el hábitat, actuando sobre condicionantes ambientales y socioeconómicos de la salud, causa de la mayor parte de las desigualdades sanitarias
La estrategia se centra en mitigar los condicionantes y determinantes de la salud en las variables ambientales y Socioeconómicas interviniendo en viviendas que presentan deficiencias en el núcleo básico sanitario compuesto por baño y cocina, asegurando de este modo un sector, que por sus características particulares y mayor complejidad técnico-constructiva no cumplen adecuadamente con sus funciones básicas de otorgar un ambiente higiénico adecuado. Las condiciones de estas viviendas hace necesario intervenir en dispositivos obsoletos para la eliminación de excretas y proveer de los recursos necesarios para asegurar una correcta higiene personal y la preparación de alimentos mediante el diseño y construcción de instalaciones que aseguren provisión de agua segura.Facultad de Ciencias Médica
Symbiosis at its limits: ecophysiological consequences of lichenization to the genus Prasiola in Antarctica
Lichens represent a symbiotic relationship between at least one fungal and one photosynthetic partner. The association between the lichen-forming fungus Mastodia tessellata (Verrucariaceae) and different species of Prasiola (Trebouxiophyceae) has an amphipolar distribution and represents a unique case study for the understanding of lichen symbiosis because of the macroalgal nature of the photobiont, the flexibility of the symbiotic interaction and the co-existence of free-living and lichenized forms in the same microenvironment. In this context, we aimed to (1) characterize the photosynthetic performance of co-occurring populations of free-living and lichenized Prasiola and (2) assess the effect of the symbiosis on water relations in Prasiola, including its tolerance of desiccation and its survival and performance under sub-zero temperatures
pRb Inactivation in Mammary Cells Reveals Common Mechanisms for Tumor Initiation and Progression in Divergent Epithelia
Retinoblastoma 1 (pRb) and the related pocket proteins, retinoblastoma-like 1 (p107) and retinoblastoma-like 2 (p130) (pRb(f), collectively), play a pivotal role in regulating eukaryotic cell cycle progression, apoptosis, and terminal differentiation. While aberrations in the pRb-signaling pathway are common in human cancers, the consequence of pRb(f) loss in the mammary gland has not been directly assayed in vivo. We reported previously that inactivating these critical cell cycle regulators in divergent cell types, either brain epithelium or astrocytes, abrogates the cell cycle restriction point, leading to increased cell proliferation and apoptosis, and predisposing to cancer. Here we report that mouse mammary epithelium is similar in its requirements for pRb(f) function; Rb(f) inactivation by T(121), a fragment of SV40 T antigen that binds to and inactivates pRb(f) proteins, increases proliferation and apoptosis. Mammary adenocarcinomas form within 16 mo. Most apoptosis is regulated by p53, which has no impact on proliferation, and heterozygosity for a p53 null allele significantly shortens tumor latency. Most tumors in p53 heterozygous mice undergo loss of the wild-type p53 allele. We show that the mechanism of p53 loss of heterozygosity is not simply the consequence of Chromosome 11 aneuploidy and further that chromosomal instability subsequent to p53 loss is minimal. The mechanisms for pRb and p53 tumor suppression in the epithelia of two distinct tissues, mammary gland and brain, are indistinguishable. Further, this study has produced a highly penetrant breast cancer model based on aberrations commonly observed in the human disease
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