331 research outputs found
A Qualitative Study Exploring How the Aims, Language and Actions of Yoga for Pregnancy Teachers May Impact Upon Women's Self-efficacy for Labour and Birth
As women's anxiety and the rate of medical intervention in labour and birth continue to increase, it is important to identify how antenatal education can increase women's confidence and their ability to manage the intense sensations of labour. To report a grounded theory study of how the aims, language and actions of yoga for pregnancy teachers may impact upon women's self-efficacy for labour and birth. Yoga for pregnancy classes in three locations were filmed. Semi-structured interviews were undertaken with the teachers to explore what they were trying to achieve in their classes, and how. Interviews and classes were transcribed and analysed using grounded theory. There was considerable consistency in the teachersâ aims, the language they used in classes and in their thinking about class structure. Four main themes emerged: creating a sisterhood, modelling labour, building confidence and enhancing learning. Teachers see yoga for pregnancy as a multi-faceted, non-prescriptive intervention that enhances women's physical, emotional and social readiness for labour and birth, and supports women to make their own decisions across the transition to parenthood. Women's self-efficacy for labour is complex and multi-factorial. This study offers insights into the factors which may be involved in increasing it. These include not only traditional elements of yoga such as postures, breathing and meditation, but also the creation of safe, women-only groups where anxieties, experiences and stories can be shared, and pain-coping techniques for labour learned and practised
Limits on the ultra-bright Fast Radio Burst population from the CHIME Pathfinder
We present results from a new incoherent-beam Fast Radio Burst (FRB) search
on the Canadian Hydrogen Intensity Mapping Experiment (CHIME) Pathfinder. Its
large instantaneous field of view (FoV) and relative thermal insensitivity
allow us to probe the ultra-bright tail of the FRB distribution, and to test a
recent claim that this distribution's slope, , is quite small. A 256-input incoherent beamformer was
deployed on the CHIME Pathfinder for this purpose. If the FRB distribution were
described by a single power-law with , we would expect an FRB
detection every few days, making this the fastest survey on sky at present. We
collected 1268 hours of data, amounting to one of the largest exposures of any
FRB survey, with over 2.4\,\,10\,deg\,hrs. Having seen no
bursts, we have constrained the rate of extremely bright events to
\,sky\,day above \,220 Jy\,ms
for between 1.3 and 100\,ms, at 400--800\,MHz. The non-detection also
allows us to rule out with 95 confidence, after
marginalizing over uncertainties in the GBT rate at 700--900\,MHz, though we
show that for a cosmological population and a large dynamic range in flux
density, is brightness-dependent. Since FRBs now extend to large
enough distances that non-Euclidean effects are significant, there is still
expected to be a dearth of faint events and relative excess of bright events.
Nevertheless we have constrained the allowed number of ultra-intense FRBs.
While this does not have significant implications for deeper, large-FoV surveys
like full CHIME and APERTIF, it does have important consequences for other
wide-field, small dish experiments
The nature of transition blazars
Blazars are classically divided into the BL Lacertae (BLL) and flat-spectrum radio quasar (FSRQ) subclasses, corresponding to radiatively inefficient and efficient accretion regimes, respectively, largely based on the equivalent width (EW) of their optical broad emission lines (BELs). However, EW-based classification criteria are not physically motivated, and a few blazars have previously "transitioned" from one subclass to the other. We present the first systematic search for these transition blazars in a sample of 602 unique pairs of repeat spectra of 354 blazars in the Sloan Digital Sky Survey, finding six clear cases. These transition blazars have bolometric Eddington ratios of ~0.3 and low-frequency synchrotron peaks, and are thus FSRQ-like. We show that the strong EW variability (up to an unprecedented factor of >60) is due to swamping of the BELs from variability in jet continuum emission, which is stronger in amplitude and shorter in timescale than typical blazars. Although these transition blazars appear to switch between FSRQ and BLL according to the phenomenologically based EW scheme, we show that they are most likely rare cases of FSRQs with radiatively efficient accretion flows and especially strongly beamed jets. These results have implications for the decrease of the apparent BLL population at high redshifts, and may lend credence to claims of a negative BLL redshift evolution
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Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy.
MotivationMultiple biological clocks govern a healthy pregnancy. These biological mechanisms produce immunologic, metabolomic, proteomic, genomic and microbiomic adaptations during the course of pregnancy. Modeling the chronology of these adaptations during full-term pregnancy provides the frameworks for future studies examining deviations implicated in pregnancy-related pathologies including preterm birth and preeclampsia.ResultsWe performed a multiomics analysis of 51 samples from 17 pregnant women, delivering at term. The datasets included measurements from the immunome, transcriptome, microbiome, proteome and metabolome of samples obtained simultaneously from the same patients. Multivariate predictive modeling using the Elastic Net (EN) algorithm was used to measure the ability of each dataset to predict gestational age. Using stacked generalization, these datasets were combined into a single model. This model not only significantly increased predictive power by combining all datasets, but also revealed novel interactions between different biological modalities. Future work includes expansion of the cohort to preterm-enriched populations and in vivo analysis of immune-modulating interventions based on the mechanisms identified.Availability and implementationDatasets and scripts for reproduction of results are available through: https://nalab.stanford.edu/multiomics-pregnancy/.Supplementary informationSupplementary data are available at Bioinformatics online
The changing landscape of care: does ethics education have a new role to play in health practice?
Fermi LAT Observations of LS I +61 303: First detection of an orbital modulation in GeV Gamma Rays
This Letter presents the first results from the observations of LSI +61 303
using Large Area Telescope data from the Fermi Gamma-Ray Space Telescope
between 2008 August and 2009 March. Our results indicate variability that is
consistent with the binary period, with the emission being modulated at 26.6
+/- 0.5 days. This constitutes the first detection of orbital periodicity in
high-energy gamma rays (20 MeV-100 GeV, HE). The light curve is characterized
by a broad peak after periastron, as well as a smaller peak just before
apastron. The spectrum is best represented by a power law with an exponential
cutoff, yielding an overall flux above 100 MeV of 0.82 +/- 0.03(stat) +/-
0.07(syst) 10^{-6} ph cm^{-2} s^{-1}, with a cutoff at 6.3 +/- 1.1(stat) +/-
0.4(syst) GeV and photon index Gamma = 2.21 +/- 0.04(stat) +/- 0.06(syst).
There is no significant spectral change with orbital phase. The phase of
maximum emission, close to periastron, hints at inverse Compton scattering as
the main radiation mechanism. However, previous very high-energy gamma ray
(>100 GeV, VHE) observations by MAGIC and VERITAS show peak emission close to
apastron. This and the energy cutoff seen with Fermi suggest the link between
HE and VHE gamma rays is nontrivial.Comment: 7 pages, 5 figures, accepted for publication in ApJ Letters 21 July
200
Gamma-Ray Emission Concurrent with the Nova in the Symbiotic Binary V407 Cygni
Novae are thermonuclear explosions on a white dwarf surface fueled by mass
accreted from a companion star. Current physical models posit that shocked
expanding gas from the nova shell can produce X-ray emission but emission at
higher energies has not been widely expected. Here, we report the Fermi Large
Area Telescope detection of variable gamma-ray (0.1-10 GeV) emission from the
recently-detected optical nova of the symbiotic star V407 Cygni. We propose
that the material of the nova shell interacts with the dense ambient medium of
the red giant primary, and that particles can be accelerated effectively to
produce pi0 decay gamma-rays from proton-proton interactions. Emission
involving inverse Compton scattering of the red giant radiation is also
considered and is not ruled out.Comment: 38 pages, includes Supplementary Online Material; corresponding
authors: C.C. Cheung, A.B. Hill, P. Jean, S. Razzaque, K.S. Woo
Early Fermi Gamma-ray Space Telescope Observations of the Quasar 3C 454.3
This is the first report of Fermi Gamma-ray Space Telescope observations of
the quasar 3C 454.3, which has been undergoing pronounced long-term outbursts
since 2000. The data from the Large Area Telescope (LAT), covering 2008 July 7
- October 6, indicate strong, highly variable gamma-ray emission with an
average flux of ~3 x 10^{-6} photons cm^{-2} s^{-1}, for energies above 100
MeV. The gamma-ray flux is variable, with strong, distinct,
symmetrically-shaped flares for which the flux increases by a factor of several
on a time scale of about three days. This variability indicates a compact
emission region, and the requirement that the source is optically thin to
pair-production implies relativistic beaming with Doppler factor delta > 8,
consistent with the values inferred from VLBI observations of superluminal
expansion (delta ~ 25). The observed gamma-ray spectrum is not consistent with
a simple power-law, but instead steepens strongly above ~2 GeV, and is well
described by a broken power-law with photon indices of ~2.3 and ~3.5 below and
above the break, respectively. This is the first direct observation of a break
in the spectrum of a high luminosity blazar above 100 MeV, and it is likely
direct evidence for an intrinsic break in the energy distribution of the
radiating particles. Alternatively, the spectral softening above 2 GeV could be
due to gamma-ray absorption via photon-photon pair production on the soft X-ray
photon field of the host AGN, but such an interpretation would require the
dissipation region to be located very close (less than 100 gravitational radii)
to the black hole, which would be inconsistent with the X-ray spectrum of the
source.Comment: Accepted by the Astrophysical Journal; corresponding authors: Greg
Madejski ([email protected]) and Benoit Lott ([email protected]
Suzaku Observations of Luminous Quasars: Revealing the Nature of High-Energy Blazar Emission in Quiescent States
We present the results from the Suzaku X-ray observations of five
flat-spectrum radio quasars (FSRQs), namely PKS0208-512, Q0827+243,
PKS1127-145, PKS1510-089 and 3C 454.3. All these sources were additionally
monitored simultaneously or quasi-simultaneously by the Fermi satellite in
gamma-rays and the Swift UVOT in the UV and optical bands, respectively. We
constructed their broad-band spectra covering the frequency range from 10^14 Hz
up to 10^25 Hz, and those reveal the nature of high-energy emission of luminous
blazars in their low-activity states. The analyzed X-ray spectra are well
fitted by a power-law model with photoelectric absorption. In the case of
PKS0208-512, PKS1127-145, and 3C 454.3, the X-ray continuum showed indication
of hard-ening at low-energies. Moreover, when compared with the previous X-ray
observations, we see a significantly increasing contribution of low-energy
photons to the total X-ray fluxes when the sources are getting fainter. The
same behavior can be noted in the Suzaku data alone. A likely explanation
involves a variable, flat-spectrum component produced via inverse-Compton (IC)
emission, plus an additional, possibly steady soft X-ray component prominent
when the source gets fainter. This soft X-ray excess is represented either by a
steep powerlaw (photon indices Gamma ~ 3 - 5) or a blackbody-type emission with
temperatures kT ~ 0.1-0.2 keV. We model the broad-band spectra spectra of the
five observed FSRQs using synchrotron self-Compton (SSC) and/or
external-Compton radiation (ECR) models. Our modeling suggests that the
difference between the low and high-activity states in luminous blazars is due
to the different total kinetic power of the jet, most likely related to varying
bulk Lorentz factor of the outflow within the blazar emission zone.Comment: 36 pages, 8 figures, 11 tables. Accepted for publication in the
Astrophysical Journal
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