58 research outputs found

    Enriching MATLAB with aspect-oriented features for developing embedded systems

    Get PDF
    This article presents an approach to enrich the MATLAB language with aspect-oriented modularity features, enabling developers to experiment different implementation characteristics and to acquire runtime data and traces without polluting their base MATLAB code. We propose a language through which programmers configure the low-level data representation of variables and expressions. Examples include specifically-tailored fixed-point data representations leading to more efficient support for the underlying hardware, e.g., digital signal processors and application-specific architectures, without built-in floating point units. This approach assists developers in adding handlers and monitoring features in a non-invasive way as well as configuring MATLAB functions with optimized implementations. Different aspect modules can be used to retarget common MATLAB code bases for different purposes and implementations. We validate the proposed approach with a set of representative examples where we attain a simple way to explore a number of properties. Experiment results and collected aspect-oriented software metrics lend support to the claims on its usefulness.This work was partially supported by FCT (Portuguese Science Foundation) under the project AMADEUS (POCTI, PTDC/EIA/70271/2006)

    Wear and surface residual stress evolution on twin-disc tests of rail/wheel steels

    Get PDF
    Twin disc tribological tests were performed in wheel and rail materials, with specimens taken from a Spanish AVE train wheel and a UIC60 rail, in a program intended to characterize their contact fatigue behavior. The X-ray diffraction technique was used to characterize the residual stress distribution at the initial and damaged stages, as well as in intermediate stages, since existing residual stresses in the surface layers of the railways steels and its evolution during contact loading can have a major influence on crack initiation and propagation

    Supine sleep and positional sleep apnea after acute ischemic stroke and intracerebral hemorrhage

    Get PDF
    OBJECTIVE: Obstructive sleep apnea is frequent during the acute phase of stroke, and it is associated with poorer outcomes. A well-established relationship between supine sleep and obstructive sleep apnea severity exists in non-stroke patients. This study investigated the frequency of supine sleep and positional obstructive sleep apnea in patients with ischemic or hemorrhagic stroke. METHODS: Patients who suffered their first acute stroke, either ischemic or hemorrhagic, were subjected to a full polysomnography, including the continuous monitoring of sleep positions, during the first night after symptom onset. Obstructive sleep apnea severity was measured using the apnea-hypopnea index, and the NIHSS measured stroke severity. RESULTS: We prospectively studied 66 stroke patients. The mean age was 57.6±11.5 years, and the mean body mass index was 26.5±4.9. Obstructive sleep apnea (apnea-hypopnea index >5) was present in 78.8% of patients, and the mean apnea-hypopnea index was 29.7±26.6. The majority of subjects (66.7%) spent the entire sleep time in a supine position, and positional obstructive sleep apnea was clearly present in the other 23.1% of cases. A positive correlation was observed between the NIHSS and sleep time in the supine position (r s = 0.5;

    Tricritical Points in the Sherrington-Kirkpatrick Model in the Presence of Discrete Random Fields

    Full text link
    The infinite-range-interaction Ising spin glass is considered in the presence of an external random magnetic field following a trimodal (three-peak) distribution. The model is studied through the replica method and phase diagrams are obtained within the replica-symmetry approximation. It is shown that the border of the ferromagnetic phase may present first-order phase transitions, as well as tricritical points at finite temperatures. Analogous to what happens for the Ising ferromagnet under a trimodal random field, it is verified that the first-order phase transitions are directly related to the dilution in the fields (represented by p0p_{0}). The ferromagnetic boundary at zero temperature also exhibits an interesting behavior: for 0<p0<p00.308560<p_{0}<p_{0}^{*} \approx 0.30856, a single tricritical point occurs, whereas if p0>p0p_{0}>p_{0}^{*} the critical frontier is completely continuous; however, for p0=p0p_{0}=p_{0}^{*}, a fourth-order critical point appears. The stability analysis of the replica-symmetric solution is performed and the regions of validity of such a solution are identified; in particular, the Almeida-Thouless line in the plane field versus temperature is shown to depend on the weight p0p_{0}.Comment: 23pages, 7 ps figure

    Assessment of coastal management options by means of multilayered ecosystem models

    Get PDF
    This paper presents a multilayered ecosystem modelling approach that combines the simulation of the biogeochemistry of a coastal ecosystem with the simulation of the main forcing functions, such as catchment loading and aquaculture activities. This approach was developed as a tool for sustainable management of coastal ecosystems. A key feature is to simulate management scenarios that account for changes in multiple uses and enable assessment of cumulative impacts of coastal activities. The model was applied to a coastal zone in China with large aquaculture production and multiple catchment uses, and where management efforts to improve water quality are under way. Development scenarios designed in conjunction with local managers and aquaculture producers include the reduction of fish cages and treatment of wastewater. Despite the reduction in nutrient loading simulated in three different scenarios, inorganic nutrient concentrations in the bay were predicted to exceed the thresholds for poor quality defined by Chinese seawater quality legislation. For all scenarios there is still a Moderate High to High nutrient loading from the catchment, so further reductions might be enacted, together with additional decreases in fish cage culture. The model predicts that overall, shellfish production decreases by 10%–28% using any of these development scenarios, principally because shellfish growth is being sustained by the substances to be reduced for improvement of water quality. The model outcomes indicate that this may be counteracted by zoning of shellfish aquaculture at the ecosystem level in order to optimize trade-offs between productivity and environmental effects. The present case study exemplifies the value of multilayered ecosystem modelling as a tool for Integrated Coastal Zone Management and for the adoption of ecosystem approaches for marine resource management. This modelling approach can be applied worldwide, and may be particularly useful for the application of coastal management regulation, for instance in the implementation of the European Marine Strategy Framework Directive

    The invertebrate lysozyme effector ILYS-3 is systemically activated in response to danger signals and confers antimicrobial protection in C. elegans

    Get PDF
    Little is known about the relative contributions and importance of antibacterial effectors in the nematode C. elegans, despite extensive work on the innate immune responses in this organism. We report an investigation of the expression, function and regulation of the six ilys (invertebrate-type lysozyme) genes of C. elegans. These genes exhibited a surprising variety of tissue-specific expression patterns and responses to starvation or bacterial infection. The most strongly expressed, ilys-3, was investigated in detail. ILYS-3 protein was expressed constitutively in the pharynx and coelomocytes, and dynamically in the intestine. Analysis of mutants showed that ILYS-3 was required for pharyngeal grinding (disruption of bacterial cells) during normal growth and consequently it contributes to longevity, as well as being protective against bacterial pathogens. Both starvation and challenge with Gram-positive pathogens resulted in ERK-MAPK-dependent up-regulation of ilys-3 in the intestine. The intestinal induction by pathogens, but not starvation, was found to be dependent on MPK-1 activity in the pharynx rather than in the intestine, demonstrating unexpected communication between these two tissues. The coelomocyte expression appeared to contribute little to normal growth or immunity. Recombinant ILYS-3 protein was found to exhibit appropriate lytic activity against Gram-positive cell wall material

    Os primórdios da organização do espaço territorial e da vila cearense: algumas notas

    Get PDF
    This paper presents, in outline, the action taken by economic agents, representatives of the Church and the Portuguese State in organizing the space of the Captaincy of Ceará in the eighteenth century. The Portuguese State founded towns in strategic locations for better capitalization of the cattle breeder economy, where first settled sesmeiros and the Church. There was no reason or justification of geopolitical nature that demanded technical and financial investments by the Portuguese in the full adequacy of the local conditions to Portuguese urban guidelines. In the face of the late occupation, the article also discusses the late cartographic representation as expressing the lack of interests of the Portuguese administration in relation to a fuller understanding of the region
    corecore