89 research outputs found
HRSC Mapping Database: A New Tool to Collect and View Available HRSC-Based Geological Maps Worldwide
We present a new online database for quick and easy access to already published HRSC-based geological mappings on Mars
The high-resolution map of Oxia Planum, Mars; the landing site of the ExoMars Rosalind Franklin rover mission
This 1:30,000 scale geological map describes Oxia Planum, Mars, the landing site for the ExoMars Rosalind Franklin rover mission. The map represents our current understanding of bedrock units and their relationships prior to Rosalind Franklinâs exploration of this location. The map details 15 bedrock units organised into 6 groups and 7 textural and surficial units. The bedrock units were identified using visible and near-infrared remote sensing datasets. The objectives of this map are (i) to identify where the most astrobiologically relevant rocks are likely to be found, (ii) to show where hypotheses about their geological context (within Oxia Planum and in the wider geological history of Mars) can be tested, (iii) to inform both the long-term (hundreds of metres to âŒ1â
km) and the short-term (tens of metres) activity planning for rover exploration, and (iv) to allow the samples analysed by the rover to be interpreted within their regional geological context
Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
Background & aims: Patients with early-onset colorectal cancer (eoCRC) are managed according to guidelines that are not age-specific. A multidisciplinary international group (DIRECt), composed of 69 experts, was convened to develop the first evidence-based consensus recommendations for eoCRC. Methods: After reviewing the published literature, a Delphi methodology was used to draft and respond to clinically relevant questions. Each statement underwent 3 rounds of voting and reached a consensus level of agreement of â„80%. Results: The DIRECt group produced 31 statements in 7 areas of interest: diagnosis, risk factors, genetics, pathology-oncology, endoscopy, therapy, and supportive care. There was strong consensus that all individuals younger than 50 should undergo CRC risk stratification and prompt symptom assessment. All newly diagnosed eoCRC patients should receive germline genetic testing, ideally before surgery. On the basis of current evidence, endoscopic, surgical, and oncologic treatment of eoCRC should not differ from later-onset CRC, except for individuals with pathogenic or likely pathogenic germline variants. The evidence on chemotherapy is not sufficient to recommend changes to established therapeutic protocols. Fertility preservation and sexual health are important to address in eoCRC survivors. The DIRECt group highlighted areas with knowledge gaps that should be prioritized in future research efforts, including age at first screening for the general population, use of fecal immunochemical tests, chemotherapy, endoscopic therapy, and post-treatment surveillance for eoCRC patients. Conclusions: The DIRECt group produced the first consensus recommendations on eoCRC. All statements should be considered together with the accompanying comments and literature reviews. We highlighted areas where research should be prioritized. These guidelines represent a useful tool for clinicians caring for patients with eoCRC
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The geography of Oxia Planum
We present the geography of Oxia Planum, the landing site for the ExoMars 2022 mission. This map provides the planetary science community with a framework to understand this, until recently, unexplored area. The map comprises (1) a mosaic of the panchromatic Context Camera (CTX) Digital Elevation Models (DEM) and Ortho Rectified Images (ORI) controlled to the High Resolution Stereo Camera (HRSC) multiorbit Digital Elevation Models (DEM) and (2) a mosaic of Colour and Stereo Surface Imaging System (CaSSIS) synthetic colour data products, registered to the CTX ORI mosaic. We define a grid of exploration quadrangles (quads) and an informal group of geographic regions to describe Oxia Planum. These regions bridge the scale gap between features observed on large areas (âŒ100s km2) and the local geography (10s km2) relevant to the Rosalind Franklin roverâs operations in Oxia Planum
First Search for Axion-Like Particles in a Storage Ring Using a Polarized Deuteron Beam
Based on the notion that the local dark-matter field of axions or axion-like
particles (ALPs) in our Galaxy induces oscillating couplings to the spins of
nucleons and nuclei (via the electric dipole moment of the latter and/or the
paramagnetic axion-wind effect), we performed the first experiment to search
for ALPs using a storage ring. For that purpose, we used an in-plane polarized
deuteron beam stored at the Cooler Synchrotron COSY, scanning momenta near 970
MeV/c. This entailed a scan of the spin precession frequency. At resonance
between the spin precession frequency of deuterons and the ALP-induced EDM
oscillation frequency there will be an accumulation of the polarization
component out of the ring plane. Since the axion frequency is unknown, the
momentum of the beam and consequently the spin precession frequency were ramped
to search for a vertical polarization change that would occur when the
resonance is crossed. At COSY, four beam bunches with different polarization
directions were used to make sure that no resonance was missed because of the
unknown relative phase between the polarization precession and the axion/ALP
field. A frequency window of 1.5-kHz width around the spin precession frequency
of 121 kHz was scanned. We describe the experimental procedure and a test of
the methodology with the help of a radiofrequency Wien filter located on the
COSY ring. No ALP resonance was observed. As a consequence an upper limit of
the oscillating EDM component of the deuteron as well as its axion coupling
constants are provided.Comment: 25 pages, 24 figures, 7 tables, 67 reference
Delphi Initiative for Early-Onset Colorectal Cancer (DIRECt) International Management Guidelines
BACKGROUND & AIMS: Patients with early-onset colorectal cancer (eoCRC) are managed according to guidelines that are not age-specific. A multidisciplinary international group (DIRECt), composed of 69 experts, was convened to develop the first evidence-based consensus recommendations for eoCRC. METHODS: After reviewing the published literature, a Delphi methodology was used to draft and respond to clinically relevant questions. Each statement underwent 3 rounds of voting and reached a consensus level of agreement of â„80%. RESULTS: The DIRECt group produced 31 statements in 7 areas of interest: diagnosis, risk factors, genetics, pathology-oncology, endoscopy, therapy, and supportive care. There was strong consensus that all individuals younger than 50 should undergo CRC risk stratification and prompt symptom assessment. All newly diagnosed eoCRC patients should receive germline genetic testing, ideally before surgery. On the basis of current evidence, endoscopic, surgical, and oncologic treatment of eoCRC should not differ from later-onset CRC, except for individuals with pathogenic or likely pathogenic germline variants. The evidence on chemotherapy is not sufficient to recommend changes to established therapeutic protocols. Fertility preservation and sexual health are important to address in eoCRC survivors. The DIRECt group highlighted areas with knowledge gaps that should be prioritized in future research efforts, including age at first screening for the general population, use of fecal immunochemical tests, chemotherapy, endoscopic therapy, and post-treatment surveillance for eoCRC patients. CONCLUSIONS: The DIRECt group produced the first consensus recommendations on eoCRC. All statements should be considered together with the accompanying comments and literature reviews. We highlighted areas where research should be prioritized. These guidelines represent a useful tool for clinicians caring for patients with eoCRC.publishedVersionPeer reviewe
The high-resolution map of Oxia Planum, Mars; the landing site of the ExoMars Rosalind Franklin rover mission
This 1:30,000 scale geological map describes Oxia Planum, Mars, the landing site for the ExoMars Rosalind Franklin rover mission. The map represents our current understanding of bedrock units and their relationships prior to Rosalind Franklinâs exploration of this location. The map details 15 bedrock units organised into 6 groups and 7 textural and surficial units. The bedrock units were identified using visible and near-infrared remote sensing datasets. The objectives of this map are (i) to identify where the most astrobiologically relevant rocks are likely to be found, (ii) to show where hypotheses about their geological context (within Oxia Planum and in the wider geological history of Mars) can be tested, (iii) to inform both the long-term (hundreds of metres to âŒ1â
km) and the short-term (tens of metres) activity planning for rover exploration, and (iv) to allow the samples analysed by the rover to be interpreted within their regional geological context
Konzeption und Implementierung eines GIS-basierten Kartierungssystems fĂŒr die geowissenschaftliche Planetenforschung
Die Kartierung planetarer Körper stellt ein wesentliches Mittel der raumfahrtgestĂŒtzten Exploration der Himmelskörper dar. Aktuell kommen zur Erstellung der planetaren Karten Geo-Informationssysteme (GIS) zum Einsatz. Ziel dieser Arbeit ist es, eine GIS-orientierte Prozesskette (Planetary Mapping System (PMS)) zu konzipieren, mit dem Schwerpunkt geologische und geomorphologische Karten planetarer OberflĂ€chen einheitlich durchfĂŒhren zu können und nachhaltig zugĂ€nglich zu machen
Genauigkeitsanalyse und Optimierung eines automationsgestĂŒtzten Prozesses zur GewĂ€ssernetzerkennung und deren Einzugsgebieten auf Erde und Mars
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