The "K-Correction" for Irradiated Emission Lines in LMXBs: Evidence for a Massive Neutron Star in X1822-371 (V691 CrA)

We study the K-correction for the case of emission lines formed in the X-ray illuminated atmosphere of a Roche lobe filling star. We compute the K-correction as function of the mass ratio 'q' and the disc flaring angle 'alpha' using a compact binary code where the companion's Roche lobe is divided into 10^5 resolution elements. We also study the effect of the inclination angle in the results. We apply our model to the case of the neutron star low-mass X-ray binary X1822-371 (V691 CrA), where a K-emission velocity K_em=300 +-8 km/s has been measured by Casares et al. (2003). Our numerical results, combined with previous determination of system parameters, yields 1.61Msun < M_NS < 2.32Msun and 0.44Msun < M_2 < 0.56Msun for the two binary components(i. e. 0.24 < q < 0.27), which provide a compelling evidence for a massive neutron star in this system. We also discuss the implications of these masses into the evolutionary history of the binary.Comment: 6 pages, 5 figures. Accepted for publication in Ap

Hβ\beta spectroscopy of the high-inclination black hole transient Swift J1357.2-0933 during quiescence

Swift J1357.2-0933 is a transient low-mass X-ray binary hosting a stellar-mass black hole. The source exhibits optical dips and very broad emission lines during both outburst and quiescence, which are thought to be the result of a high orbital inclination. We present phase-resolved spectroscopy obtained with the 10.4m Gran Telescopio Canarias (GTC). The spectra focus on the $\rm{H}\beta$ spectral region during X-ray quiescence. The emission line is exceptionally broad (full width at half maximum, FWHM > 4000 \AA), in agreement with previous studies focused on $\rm{H}\alpha$. A two-Gaussian fit to the prominent double-peaked profile reveals a periodic variability in the centroid position of the line. We also produced a diagnostic diagram aimed at constraining additional orbital parameters. Together, they allow us to independently confirm the orbital period of the system using a new dataset obtained five years after the previous outburst. However, our estimates for both the systemic velocity and the radial velocity semi-amplitude of the black hole reveal larger values than those found in previous studies. We argue that this could be explained by the precession of the disc and the presence of a hotspot. We found evidence of a narrow inner core in the double-peaked H$\beta$ emission profile. We studied its evolution across the orbit, finding that it is likely to result from the occultation of inner material by the outer rim bulge, further supporting the high orbital inclination hypothesis.Comment: 6 pages, 4 figure

Correlated optical, X-ray, and $-ray flaring activity seen with INTEGRAL during the 2015 outburst of V404 Cygni

Reproduced with permission from Astronomy & Astrophysics. © 2015 ESO.After 25 years of quiescence, the microquasar V404 Cyg entered a new period of activity in June 2015. This X-ray source is known to undergo extremely bright and variable outbursts seen at all wavelengths. It is therefore an object of prime interest to understand the accretion-ejection connections. These can, however, only be probed through simultaneous observations at several wavelengths. We made use of the INTEGRAL instruments to obtain long, almost uninterrupted observations from 2015 June 20th, 15:50 UTC to June 25th, 4:05 UTC, from the optical V-band, up to the soft γ-rays. V404 Cyg was extremely variable in all bands, with the detection of 18 flares with fluxes exceeding 6 Crab (20--40 keV) within 3 days. The flare recurrence can be as short as ∼ 20~min from peak to peak. A model-independent analysis shows that the >6 Crab flares have a hard spectrum. A simple 10--400 keV spectral analysis of the off-flare and flare periods shows that the variation in intensity is likely to be due to variations of a cut-off power law component only. The optical flares seem to be at least of two different types: one occurring in simultaneity with the X-ray flares, the other showing a delay greater than 10 min. The former could be associated with X-ray reprocessing by either an accretion disk or the companion star. We suggest that the latter are associated with plasma ejections that have also been seen in radio.Peer reviewe

Flares, wind and nebulae: the 2015 December mini-outburst of V404 Cygni

After more than 26 years in quiescence, the black hole transient V404 Cyg went into a luminous outburst in June 2015, and additional activity was detected in late December of the same year. Here, we present an optical spectroscopic follow-up of the December mini-outburst, together with X-ray, optical and radio monitoring that spanned more than a month. Strong flares with gradually increasing intensity are detected in the three spectral ranges during the ∼ 10 days following the Swift trigger. Our optical spectra reveal the presence of a fast outflowing wind, as implied by the detection of a P-Cyg profile (He i–5876 ˚A) with a terminal velocity of ∼ 2500 kms−1 . Nebularlike spectra – with an H α equivalent width of ∼ 500 ˚A – are also observed. All these features are similar to those seen during the main June 2015 outburst. Thus, the fast optical wind simultaneous with the radio jet is most likely present in every V404 Cyg outburst. Finally, we report on the detection of a strong radio flare in late January 2016, when X-ray and optical monitoring had stopped due to Sun constraints

Immune-mediated mechanisms influencing the efficacy of anticancer therapies

Conventional anticancer therapies, such as chemotherapy, radiotherapy, and targeted therapy, are designed to kill cancer cells. However, the efficacy of anticancer therapies is not only determined by their direct effects on cancer cells but also by off-target effects within the host immune system. Cytotoxic treatment regimens elicit several changes in immune-related parameters including the composition, phenotype, and function of immune cells. Here we discuss the impact of innate and adaptive immune cells on the success of anticancer therapy. In this context we examine the opportunities to exploit host immune responses to boost tumor clearing, and highlight the challenges facing the treatment of advanced metastatic disease

The 2005 outburst of the halo black hole X-ray transient XTE J1118+480

We present optical and infrared monitoring of the 2005 outburst of the halo black hole X-ray transient XTE J1118+480. We measured a total outburst amplitude of ~5.7 ± 0.1 mag in the R band and ~5 mag in the infrared J, H, and Ks bands. The hardness ratio HR2 (5-12 keV : 3-5 keV) from the RXTE ASM data is 1.53 ± 0.02 at the peak of the outburst, indicating a hard spectrum. Both the shape of the light curve and the ratio LX(1-10 keV)/Lopt resemble the minioutbursts observed in GRO J0422+32 and XTE J1859+226. During early decline, we find a 0.02 mag amplitude variation consistent with a superhump modulation, like the one observed during the 2000 outburst. Similarly, XTE J1118+480 displayed a double-humped ellipsoidal modulation distorted by a superhump wave when settled into a near-quiescence level, suggesting that the disk expanded to the 3 : 1 resonance radius after outburst, where it remained until early quiescence. The system reached quiescence at R = 19.02 ± 0.03, about 3 months after the onset of the outburst. The optical rise preceded the X-ray rise by at most 4 days. The spectral energy distributions (SEDs) at the different epochs during outburst are all quasi-power laws with Fν να increasing toward the blue. At the peak of the outburst, we derived α = 0.49 ± 0.04 for the optical data alone and α = 0.1 ± 0.1 when fitting solely the infrared. This difference between the optical and the infrared SEDs suggests that the infrared is dominated by a different component (a jet?), whereas the optical is presumably showing the disk evolution

Hard-state Accretion Disk Winds from Black Holes: The Revealing Case of MAXI J1820+070

We report on a detailed optical spectroscopic follow-up of the black hole (BH) transient MAXI J1820+070 (ASASSN-18ey). The observations cover the main part of the X-ray binary outburst, when the source alternated between hard and soft states following the classical pattern widely seen in other systems. We focus the analysis on the He I emission lines at 5876 and 6678 angstrom, as well as on H alpha. We detect clear accretion disk wind features (P-Cyg profiles and broad emission line wings) in the hard state, both during outburst rise and decay. These are not witnessed during the several months long soft state. However, our data suggest that the visibility of the outflow might be significantly affected by the ionization state of the accretion disk. The terminal velocity of the wind is above similar to 1200 km s(-1), which is similar to outflow velocities derived from (hard-state) optical winds and (soft-state) X-ray winds in other systems. The wind signatures, in particular the P-Cyg profiles, are very shallow, and their detection has only been possible thanks to a combination of source brightness and intense monitoring at very high signal-to-noise. This study indicates that cold, optical winds are most likely a common feature of BH accretion, and therefore, that wind-like outflows are a general mechanism of mass and angular momentum removal operating throughout the entire X-ray binary outburst