103 research outputs found

    COLLECTIVE MEMORY IN A POST-INDUSTRIAL COMMUNITY, ANACONDA, MONTANA: A MIXED METHODS APPROACH FOR UNDERSTANDING COMMUNITY RESILIENCE AND TRANSITIONS

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    Post-industrial rural communities across the United States are experiencing economic, social, and environmental changes. Successful transitions depend on the ability to navigate change and maintain a quality of life, or a community’s resilience. These communities do not start with a blank slate, but rather their present and future decision-making, priorities, and planning are influenced by their pasts. Many of these communities retain strong ties to their extractive identities, histories, and landscapes. Often, collective memories, or how people remember and share knowledge and experiences related to their identity, perpetuate narratives and stories about their pasts. This research draws attention to the social dimensions of post-industrial rural community change. The town of Anaconda, Montana— a former smelting town, Superfund site, and an aspiring tourism and recreation destination— provides an instructive case study to examine the role of collective memory in change and transition. This dissertation uses a mixed methods approach including 33 semi-structured interviews with community leaders, a household survey (n = 347), and 22 phenomenological interviews with community members. Centering analysis on the community scale, research found that collective memory impacts community resilience. Collective memory functions differently throughout time— it can act as a galvanizing force to mobilize and aid in recovery or as a constraint to change and innovative thinking. This research also created quantitative collective memory measures which were tested in a model with community resilience. Findings illuminate a complex temporal relationship between the past, present, and future, where the past influences how communities perceive their resilience, which in turn, influences how they plan and hope for the future. Utilizing collective memory as a springboard, investigation of the community’s lived experiences shed light into the complicated nature of contamination cleanup, where these spaces are rich sources of meaning and memory. Community experiences revealed the need for historically informed cleanups in processes such as Superfund and offered practical recommendations for community engagement. Together this dissertation highlights the importance of studying the social dimensions of post-industrial rural communities for more effective decision-making and community engagement

    Research Meets Policy: Getting the Media Involved

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    This explainer document is the fourth in a four part series based on Research Meets Policy at SFU 2021 - a virtual summer institute hosted by the SFU Knowledge Mobilization Hub.The media is an effective channel for reaching policy makers, as it is a proven way to gain the interest and attention of voters on a particular topic, or as another way to attract the attention of policy makers directly. When short on time, many policy makers rely on trusted voices on Twitter or other media outlets for quick takes on pressing issues. In this explainer, we share how you can get started engaging the media for communicating to policy makers

    Development of the Human Fetal Kidney from Mid to Late Gestation in Male and Female Infants

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    BACKGROUND During normal human kidney development, nephrogenesis (the formation of nephrons) is complete by term birth, with the majority of nephrons formed late in gestation. The aim of this study was to morphologically examine nephrogenesis in fetal human kidneys from 20 to 41weeks of gestation. METHODS Kidney samples were obtained at autopsy from 71 infants that died acutely in utero or within 24h after birth. Using image analysis, nephrogenic zone width, the number of glomerular generations, renal corpuscle cross-sectional area and the cellular composition of glomeruli were examined. Kidneys from female and male infants were analysed separately. FINDINGS The number of glomerular generations formed within the fetal kidneys was directly proportional to gestational age, body weight and kidney weight, with variability between individuals in the ultimate number of generations (8 to 12) and in the timing of the cessation of nephrogenesis (still ongoing at 37weeks gestation in one infant). There was a slight but significant (r2=0.30, P=0.001) increase in renal corpuscle cross-sectional area from mid gestation to term in females, but this was not evident in males. The proportions of podocytes, endothelial and non-epithelial cells within mature glomeruli were stable throughout gestation. INTERPRETATION These findings highlight spatial and temporal variability in nephrogenesis in the developing human kidney, whereas the relative cellular composition of glomeruli does not appear to be influenced by gestational age.This study was supported by funding from the National Health and Medical Research Council (NHMRC) (1011136) of Australia and National Institutes of Health (NIH) USA grant 3U01DK094526-04S1 (PI A P McMahon). Author Danica Ryan was the recipient of the Biomedicine Discovery Scholarship from Monash University and author Megan R. Sutherland was supported by a NHMRC CJ Martin Fellowship

    Geographic Variations in Retention in Care among HIV-Infected Adults in the United States

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    ObjectiveTo understand geographic variations in clinical retention, a central component of the HIV care continuum and key to improving individual- and population-level HIV outcomes.DesignWe evaluated retention by US region in a retrospective observational study.MethodsAdults receiving care from 2000–2010 in 12 clinical cohorts of the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD) contributed data. Individuals were assigned to Centers for Disease Control and Prevention (CDC)-defined regions by residential data (10 cohorts) and clinic location as proxy (2 cohorts). Retention was ≥2 primary HIV outpatient visits within a calendar year, >90 days apart. Trends and regional differences were analyzed using modified Poisson regression with clustering, adjusting for time in care, age, sex, race/ethnicity, and HIV risk, and stratified by baseline CD4+ count.ResultsAmong 78,993 adults with 444,212 person-years of follow-up, median time in care was 7 years (Interquartile Range: 4–9). Retention increased from 2000 to 2010: from 73% (5,000/6,875) to 85% (7,189/8,462) in the Northeast, 75% (1,778/2,356) to 87% (1,630/1,880) in the Midwest, 68% (8,451/12,417) to 80% (9,892/12,304) in the South, and 68% (5,147/7,520) to 72% (6,401/8,895) in the West. In adjusted analyses, retention improved over time in all regions (p<0.01, trend), although the average percent retained lagged in the West and South vs. the Northeast (p<0.01).ConclusionsIn our population, retention improved, though regional differences persisted even after adjusting for demographic and HIV risk factors. These data demonstrate regional differences in the US which may affect patient care, despite national care recommendations

    Review of the evidence regarding the use of antenatal multiple micronutrient supplementation in low- and middle-income countries.

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    Inadequate micronutrient intakes are relatively common in low- and middle-income countries (LMICs), especially among pregnant women, who have increased micronutrient requirements. This can lead to an increase in adverse pregnancy and birth outcomes. This review presents the conclusions of a task force that set out to assess the prevalence of inadequate micronutrient intakes and adverse birth outcomes in LMICs; the data from trials comparing multiple micronutrient supplements (MMS) that contain iron and folic acid (IFA) with IFA supplements alone; the risks of reaching the upper intake levels with MMS; and the cost-effectiveness of MMS compared with IFA. Recent meta-analyses demonstrate that MMS can reduce the risks of preterm birth, low birth weight, and small for gestational age in comparison with IFA alone. An individual-participant data meta-analysis also revealed even greater benefits for anemic and underweight women and female infants. Importantly, there was no increased risk of harm for the pregnant women or their infants with MMS. These data suggest that countries with inadequate micronutrient intakes should consider supplementing pregnant women with MMS as a cost-effective method to reduce the risk of adverse birth outcomes

    Denial of long-term issues with agriculture on tropical peatlands will have devastating consequences

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    Non peer reviewe

    Health, education, and social care provision after diagnosis of childhood visual disability

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    Aim: To investigate the health, education, and social care provision for children newly diagnosed with visual disability.Method: This was a national prospective study, the British Childhood Visual Impairment and Blindness Study 2 (BCVIS2), ascertaining new diagnoses of visual impairment or severe visual impairment and blindness (SVIBL), or equivalent vi-sion. Data collection was performed by managing clinicians up to 1-year follow-up, and included health and developmental needs, and health, education, and social care provision.Results: BCVIS2 identified 784 children newly diagnosed with visual impairment/SVIBL (313 with visual impairment, 471 with SVIBL). Most children had associated systemic disorders (559 [71%], 167 [54%] with visual impairment, and 392 [84%] with SVIBL). Care from multidisciplinary teams was provided for 549 children (70%). Two-thirds (515) had not received an Education, Health, and Care Plan (EHCP). Fewer children with visual impairment had seen a specialist teacher (SVIBL 35%, visual impairment 28%, χ2p < 0.001), or had an EHCP (11% vs 7%, χ2p < 0 . 01).Interpretation: Families need additional support from managing clinicians to access recommended complex interventions such as the use of multidisciplinary teams and educational support. This need is pressing, as the population of children with visual impairment/SVIBL is expected to grow in size and complexity.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited

    Abstracts from the NIHR INVOLVE Conference 2017

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    Safety, immunogenicity, and reactogenicity of BNT162b2 and mRNA-1273 COVID-19 vaccines given as fourth-dose boosters following two doses of ChAdOx1 nCoV-19 or BNT162b2 and a third dose of BNT162b2 (COV-BOOST): a multicentre, blinded, phase 2, randomised trial

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