15 research outputs found

    Clinical utilization of genomics data produced by the international Pseudomonas aeruginosa consortium

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    The International Pseudomonas aeruginosa Consortium is sequencing over 1000 genomes and building an analysis pipeline for the study of Pseudomonas genome evolution, antibiotic resistance and virulence genes. Metadata, including genomic and phenotypic data for each isolate of the collection, are available through the International Pseudomonas Consortium Database (http://ipcd.ibis.ulaval.ca/). Here, we present our strategy and the results that emerged from the analysis of the first 389 genomes. With as yet unmatched resolution, our results confirm that P. aeruginosa strains can be divided into three major groups that are further divided into subgroups, some not previously reported in the literature. We also provide the first snapshot of P. aeruginosa strain diversity with respect to antibiotic resistance. Our approach will allow us to draw potential links between environmental strains and those implicated in human and animal infections, understand how patients become infected and how the infection evolves over time as well as identify prognostic markers for better evidence-based decisions on patient care

    Iconic chat 99

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    There has been an increase in the need for communication between people of different cultures in the last decade. This project breaks the language barrier between people by allowing visual communication using [an] iconic language. The program was implemented with high regard to icon design so that it can be easily understood and used. Testing results have shown that this is a viable form of a communication, [one] that is easily learned and used

    Zinc Organometallics

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