La RSC en el fútbol. Estudio del Athletic Club, A.D. Alcorcón y Real Valladolid C.F

¿Es aplicable la Responsabilidad Social Corporativa al fútbol profesional? Actualmente, el fútbol ha trascendido la esfera deportiva y se ha convertido en un espectáculo capaz de tener un impacto económico en la economía de los países. Los clubes de fútbol cuentan con un gran eco social y mediático y constituyen un magnífico vehículo de formación. Sin embargo, y a pesar de ese interés, en muchos casos estas demandas sociales se quedan solo en buenas intenciones. Bajo este contexto se articula la presente investigación que a través del estudio del caso de tres clubes de fútbol (A.D. Alcorcón, Athletic Club y Real Valladolid C.F.) busca conocer en profundidad el concepto y las características de la Responsabilidad Social Corporativa, y su posterior aplicación en el fútbol, en aras de comprender la importancia que esta ha adquirido en las entidades deportivas. Para su consecución, nos apoyamos en una metodología cuantitativa, con la realización de encuestas y análisis de contenido de los sitios web; y cualitativa, mediante la realización de entrevistas a los responsables de la RSC en los tres clubes mencionados.Is Corporate social responsibility applicable to the professional football? Nowadays, the football has come out the sports sphere and has turned into a spectacle capable of having an economic impact in the economy of the countries. The clubs of football possess a great social and media echo and constitute a magnificent vehicle of formation. Nevertheless, and in spite of this interest, in many cases these social demands remain alone in good intentions. Under this context the present investigation articulates that across the study of the case of three clubs of football (A.D. Alcorcón, Athletic Club and Real Valladolid C.F.) it seeks to know in depth the concept and the characteristics of the Corporate social responsibility, and his later application in the football, in altars of understanding the importance that this one has acquired in the sporting bodies. For his attainment, we rest on a quantitative methodology, with the accomplishment of surveys and analysis of content of the web sites; and qualitative, by means of the accomplishment of interviews to the persons in charge of the RSC in three mentioned clubs.Departamento de Historia Moderna, Contemporánea y de América, Periodismo y Comunicación Audiovisual y PublicidadGrado en Periodism

Análisis de la investigación sobre mindfulness entre 2008-2012: una aproximación a través del análisis bibliométrico

The present essay provides the existing world records and data concerning the ‘mindfulness’ between 2008 and 2012, extracted by means of bibliometric analysis from the data bases ISI Web of Knowledge (1215 articles found). Not only have been productivity and temporal range analyzed, but also scientific production rates by countries, languages, authors, periodicals, universities and supporting organisms, identifying the highest productivity rates. Knowledge areas and categories have been considered, as well as the citations received. Results show how a steady increase of scientific productivity and number of citations received within five years, and the coverage of large topics are the most significant features. In addition, certain supporting organisms, periodicals, universities and the US, appear to be the referents when publishing articles related to the ‘mindfulness’.En este trabajo, se presentan los datos obtenidos a través del análisis bibliométrico, de los artículos encontrados a nivel mundial sobre mindfulness entre los años 2008 y 2012. Los datos han sido extraídos de la base de datos ISI web of Knowledge y el número de artículos encontrados en la misma es de 1215. Se han analizado la productividad y distribución temporal, así como la producción científica por países, idiomas, autores, revistas, universidades y organismos financiadores, identificando aquellos más productivos. Así mismo, se han estudiado las áreas y categorías que aparecen en los artículos científicos, así como las citas recibidas. Los resultados indican, como aspectos más relevantes, un incremento regular de la productividad científica y del número de citas recibidas a lo largo de estos cinco años, y una amplia gama de temáticas cubiertas. Además, aparecen como referentes determinados organismos financiadores, revistas y universidades, y un país, Estados Unidos, en la publicación de artículos sobre mindfulness

Variables relacionadas con el abandono terapéutico en una adaptación grupal del Protocolo Unificado para el tratamiento transdiagnóstico de los trastornos emocionales. Un estudio preliminar

Due to the high number of people requesting psychological help and the scarcity of professional resources available to many psychological assistance services, it is necessary to promote the implementation of therapeutic modalities that optimize these resources; a promising alternative is the group adaptation of Barlow's unified protocol (Barlow et al., 2018). However, it is necessary to identify the patients who can most likely benefit from this group protocol and which are the variables that characterize those with a higher risk of abandoning this type of intervention. This study was carried out on a total sample of 54 people who initiated a group adaptation of Barlow's Unified Protocol, in the Psychological Assistance Service of the Pontifical University of Salamanca. A group of patients who completed the treatment (n=37) was compared with a group who abandoned it at some point (n=17). Measures of anxiety, depression, personality variables, quality of life, interference and self-compassion were taken. The results indicate the presence of statistically significant differences in anxiety symptoms and the level of interference of the problem in daily life, these being more severe in the group that abandoned treatment; patients who complete the treatment, score significantly higher in the shared humanity variable, involved in the processes of empathy and belonging to the group; likewise, differences are observed, at the limit of statistical significance, in the depression and quality of life variables, with the patients in the group that abandoned treatment obtaining the highest scores in depression and the lowest in quality of life. These preliminary results show some characteristics that can be used to identify, in an initial assessment, the possible beneficiaries of this format and optimize the therapeutic alternatives offered.Debido al elevado número de personas que solicitan ayuda psicológica y a la escasez de recursos profesionales de los que disponen muchos servicios, se hace necesario fomentar la puesta en marcha de modalidades terapéuticas que optimicen dichos recursos; una alternativa prometedora es la adaptación grupal del protocolo unificado de Barlow para el abordaje de los trastornos emocionales (Barlow et al., 2018). No obstante, se precisa identificar qué pacientes pueden beneficiarse con más probabilidades de éxito de este protocolo grupal y qué variables caracterizan a los pacientes con mayor riesgo de abandono en este tipo de intervención. El presente estudio se ha realizado sobre una muestra total de 54 personas que iniciaron una adaptación grupal de dicho protocolo, en el Servicio de Asistencia Psicológica de la Universidad Pontificia de Salamanca. Se ha comparado un grupo de pacientes que completan el tratamiento (n= 37) con un grupo que abandona en algún momento el mismo (n=17). Se tomaron medidas de ansiedad, depresión, variables de personalidad, calidad de vida, interferencia y autocompasión. Los resultados indican la presencia de diferencias estadísticamente significativas en los síntomas de ansiedad y en el nivel de interferencia del problema en la vida diaria siendo éstos más severos en el grupo que abandona el tratamiento; los pacientes que completan el tratamiento puntúan significativamente más alto en la variable humanidad compartida, implicada en los procesos de empatía y pertenencia al grupo; asimismo, se observan diferencias en el límite de la significación estadística, en las variables depresión y calidad de vida, siendo los pacientes del grupo que abandona el tratamiento, los que obtienen puntuaciones más elevadas en depresión y más bajas en calidad de vida. Estos resultados preliminares señalan algunas características para identificar, en la evaluación inicial, a los posibles beneficiarios de este formato y optimizar las alternativas terapéuticas ofrecidas

Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study

Background: Limited studies have evaluated the joint influence of redox-related metals and genetic variation on metabolic pathways. We analyzed the association of 11 metals with metabolic patterns, and the interacting role of candidate genetic variants, in 1145 participants from the Hortega Study, a population-based sample from Spain. Methods: Urine antimony (Sb), arsenic, barium (Ba), cadmium (Cd), chromium (Cr), cobalt (Co), molybdenum (Mo) and vanadium (V), and plasma copper (Cu), selenium (Se) and zinc (Zn) were measured by ICP-MS and AAS, respectively. We summarized 54 plasma metabolites, measured with targeted NMR, by estimating metabolic principal components (mPC). Redox-related SNPs (N = 291) were measured by oligo-ligation assay. Results: In our study, the association with metabolic principal component (mPC) 1 (reflecting non-essential and essential amino acids, including branched chain, and bacterial co-metabolism versus fatty acids and VLDL subclasses) was positive for Se and Zn, but inverse for Cu, arsenobetaine-corrected arsenic (As) and Sb. The association with mPC2 (reflecting essential amino acids, including aromatic, and bacterial co-metabolism) was inverse for Se, Zn and Cd. The association with mPC3 (reflecting LDL subclasses) was positive for Cu, Se and Zn, but inverse for Co. The association for mPC4 (reflecting HDL subclasses) was positive for Sb, but inverse for plasma Zn. These associations were mainly driven by Cu and Sb for mPC1; Se, Zn and Cd for mPC2; Co, Se and Zn for mPC3; and Zn for mPC4. The most SNP-metal interacting genes were NOX1, GSR, GCLC, AGT and REN. Co and Zn showed the highest number of interactions with genetic variants associated to enriched endocrine, cardiovascular and neurological pathways. Conclusions: Exposures to Co, Cu, Se, Zn, As, Cd and Sb were associated with several metabolic patterns involved in chronic disease. Carriers of redox-related variants may have differential susceptibility to metabolic alterations associated to excessive exposure to metals.This work was supported by the Strategic Action for Research in Health sciences [CP12/03080, PI15/00071, PI10/0082, PI13/01848, PI14/00874, PI16/01402, PI21/00506 and PI11/00726], CIBER Fisio patología Obesidad y Nutrición (CIBEROBN) (CIBER-02-08-2009, CB06/03 and CB12/03/30,016), the State Agency for Research (PID2019-108973RB- C21 and C22), the Valencia Government (GRUPOS 03/101; PROMETEO/2009/029 and ACOMP/2013/039, IDI FEDER/2021/072 and GRISOLIAP/2021/119), the Castilla-Leon Government (GRS/279/A/08) and European Network of Excellence Ingenious Hypercare (EPSS-037093) from the European Commission. The Strategic Action for Research in Health sciences, CIBERDEM and CIBEROBN are initiatives from Carlos III Health Institute Madrid and cofunded with European Funds for Regional Development (FEDER). The State Agency for Research and Carlos III Health Institute belong to the Spanish Ministry of Science and Innovation. ADR received the support of a fellowship from “la Caixa” Foundation (ID 100010434) (fellowship code “LCF/BQ/DR19/11740016”). MGP received the support of a fellowship from “la Caixa” Foundation (ID 100010434, fellowship code LCFLCF/BQ/DI18/11660001). The funding bodies had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.S

An international cross-sectional investigation on social media, fitspiration content exposure, and related risks during the COVID-19 self-isolation period.

With the global COVID-19 pandemic, governments from many countries in the world implemented various restrictions to prevent the SARS-Cov-2 virus's spread, including social distancing measures, quarantine, in-home lockdown, and the closure of services and public spaces. This led to an in-creased use of social media platforms to make people feel more connected, but also to maintain physical activity while self-isolating. Concerns about physical appearance and the desire to keep or reach a muscular and toned ideal body, might have further reinforced the engagement in fitness-related social media activities, like sharing progresses in training achievements or following more fitness contents on popular profiles. To better understand the underlying relation among these factors, the present study investigates 729 responses to the Exercise Addiction Inventory (EAI), the Appearance Anxiety Inventory (AAI), the Self-Compassion Scale (SCS) and their association to social media usage and compares the results cross-culturally in five countries (Spain, Lithuania, United Kingdom, Japan, and Hungary). Findings highlight significant differences between males and females, espe-cially in regard to the time spent online (U = 477.5, p = 0.036). Greater levels of appearance anxiety were associated with the exposure to fitness-related contents on social media. These results strongly confirm the previously highlighted association between fitspiration media and body image anxiety predominantly in females. Clinical implications and future considerations in terms of prevention and treatment in a situation of global emergency are also discussed

Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung cancer

Single nucleotide polymorphisms (SNPs) may modulate individual susceptibility to carcinogens. We designed a genome-wide association study to characterize individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced non-small cell lung cancer (NSCLC), and we validated our results. We hypothesized that this strategy would enrich the frequencies of the alleles that contribute to the observed traits. We genotyped 2.37 million SNPs in 95 extreme phenotype individuals, that is: heavy smokers that either developed NSCLC at an early age (extreme cases); or did not present NSCLC at an advanced age (extreme controls), selected from a discovery set (n = 3631). We validated significant SNPs in 133 additional subjects with extreme phenotypes selected from databases including >39,000 individuals. Two SNPs were validated: rs12660420 (pcombined  = 5.66 × 10-5 ; ORcombined  = 2.80), mapping to a noncoding transcript exon of PDE10A; and rs6835978 (pcombined  = 1.02 × 10-4 ; ORcombined  = 2.57), an intronic variant in ATP10D. We assessed the relevance of both proteins in early-stage NSCLC. PDE10A and ATP10DmRNA expressions correlated with survival in 821 stage I-II NSCLC patients (p = 0.01 and p < 0.0001). PDE10A protein expression correlated with survival in 149 patients with stage I-II NSCLC (p = 0.002). In conclusion, we validated two variants associated with extreme phenotypes of high and low risk of developing tobacco-induced NSCLC. Our findings may allow to identify individuals presenting high and low risk to develop tobacco-induced NSCLC and to characterize molecular mechanisms of carcinogenesis and resistance to develop NSCLC.This work was supported by the Spanish Society of Medical Oncology; Fundación SEOM and Fundación Salud 2000; and Government of Navarra.S

Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung cancer

Single nucleotide polymorphisms (SNPs) may modulate individual susceptibility to carcinogens. We designed a genome-wide association study to characterize individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced non-small cell lung cancer (NSCLC), and we validated our results. We hypothesized that this strategy would enrich the frequencies of the alleles that contribute to the observed traits. We genotyped 2.37 million SNPs in 95 extreme phenotype individuals, that is: heavy smokers that either developed NSCLC at an early age (extreme cases); or did not present NSCLC at an advanced age (extreme controls), selected from a discovery set (n=3631). We validated significant SNPs in 133 additional subjects with extreme phenotypes selected from databases including >39,000 individuals. Two SNPs were validated: rs12660420 (p(combined)=5.66x10(-5); ORcombined=2.80), mapping to a noncoding transcript exon of PDE10A; and rs6835978 (p(combined)=1.02x10(-4); ORcombined=2.57), an intronic variant in ATP10D. We assessed the relevance of both proteins in early-stage NSCLC. PDE10A and ATP10D mRNA expressions correlated with survival in 821 stage I-II NSCLC patients (p=0.01 and p<0.0001). PDE10A protein expression correlated with survival in 149 patients with stage I-II NSCLC (p=0.002). In conclusion, we validated two variants associated with extreme phenotypes of high and low risk of developing tobacco-induced NSCLC. Our findings may allow to identify individuals presenting high and low risk to develop tobacco-induced NSCLC and to characterize molecular mechanisms of carcinogenesis and resistance to develop NSCLC

Exploring the Relationship Between Mental Well-Being, Exercise Routines, and the Intake of Image and Performance Enhancing Drugs During the Coronavirus Disease 2019 Pandemic : A Comparison Across Sport Disciplines

Funding Information: This research was supported by the European Network for the Problematic Use of the Internet, the COST European Cooperation in Science and Technology, a Grant-in-Aid for Scientific Research on Innovative Areas (Ministry of Education, Culture Sports, Science and Technology, Japan, 16H06400, 16H06402, 16H06395, and 16H06397), a Grant-in-Aid for Scientific Research (A) (Japan Society for The Promotion of Science, 19H00518), a Grant-in-Aid by the Smoking Research Foundation, and Grant-in-Aid for Young Scientists (20K13821), the Hungarian National Research, Development and Innovation Office (KKP126835; ELTE Thematic Excellence Programme 2020, KP2020-IKA-05). Publisher Copyright: © Copyright © 2021 Shibata, Burkauskas, Dores, Kobayashi, Yoshimura, Simonato, De Luca, Cicconcelli, Giorgetti, Carvalho, Barbosa, Monteiro, Murai, Gómez-Martínez, Demetrovics, Ábel, Szabo, Ventola, Arroyo-Anlló, Santos-Labrador, Griskova-Bulanova, Pranckeviciene, Bersani, Fujiwara and Corazza.Introduction: Physical distancing under the coronavirus disease 2019 (COVID-19) pandemic had a significant impact on lifestyles, including exercise routines. In this study, we examined the relationship between mental health and addictive behaviors, such as excessive exercise and the use of image and performance enhancing drugs (IPEDs) across 12 sport disciplines. Materials and methods: A large cross-sectional sample of the adult population (N = 2,295) was surveyed. The mean age was 33.09 (SD = 11.40). The number of male participants was 668 (30.0%). The use of IPEDs was assessed in conjunction with psychometric measures such as the Exercise Addiction Inventory (EAI) and the Appearance Anxiety Inventory (AAI). The participants were grouped into activity group (AG) and non-activity group (NAG) according to the presence or absence of their exercise habits. The results were compared between these groups, as well as across sport disciplines, while taking into account the relationship between different psychological measures and IPEDs consumption. Results: The frequency of IPEDs use was higher among AG (34.6%) than NAG (14.6%), although AG participants reported less history of addictions (7.1%) than NAG (11.8%). The logistic regression analysis revealed that scores equal to or above cutoff points, in both the EAI and AAI, predicted the IPEDs use. Regarding the differences across the various sport disciplines, those who were involved in practicing Weight Lifting and Cross Fit were found to be more at risk of excessive exercising and more inclined to use a wide range of IPEDs. Conclusions: Although exercise could help to increase well-being and prevent addictions during the COVID-19 pandemic, our results show that those in the AG are particularly vulnerable to excessive IPEDs use. Sport disciplines associated with higher EAI and AAI scores have also shown a higher tendency to excessive IPEDs use. Furthermore, the factor of having above the cutoff scores in EAI or AAI in each sport could indicate larger IPEDs consumption regardless of the discipline. In light of the current findings, it is necessary to better define the “non-excessive” levels of exercise in various sport disciplines and an adequate intake of IPEDs to ensure the safety and well-being of people during a pandemic.Peer reviewe

Antibody conversion rates to SARS-CoV-2 in saliva from children attending summer schools in Barcelona, Spain.

Background: Surveillance tools to estimate viral transmission dynamics in young populations are essential to guide recommendations for school opening and management during viral epidemics. Ideally, sensitive techniques are required to detect low viral load exposures among asymptomatic children. We aimed to estimate SARS-CoV-2 infection rates in children and adult populations in a school-like environment during the initial COVID-19 pandemic waves using an antibody-based field-deployable and non-invasive approach. Methods: Saliva antibody conversion defined as ≥ 4-fold increase in IgM, IgA, and/or IgG levels to five SARS-CoV-2 antigens including spike and nucleocapsid constructs was evaluated in 1509 children and 396 adults by high-throughput Luminex assays in samples collected weekly in 22 summer schools and 2 pre-schools in 27 venues in Barcelona, Spain, from June 29th to July 31st, 2020. Results: Saliva antibody conversion between two visits over a 5-week period was 3.22% (49/1518) or 2.36% if accounting for potentially cross-reactive antibodies, six times higher than the cumulative infection rate (0.53%) assessed by weekly saliva RT-PCR screening. IgG conversion was higher in adults (2.94%, 11/374) than children (1.31%, 15/1144) (p=0.035), IgG and IgA levels moderately increased with age, and antibodies were higher in females. Most antibody converters increased both IgG and IgA antibodies but some augmented either IgG or IgA, with a faster decay over time for IgA than IgG. Nucleocapsid rather than spike was the main antigen target. Anti-spike antibodies were significantly higher in individuals not reporting symptoms than symptomatic individuals, suggesting a protective role against COVID-19. Conclusion: Saliva antibody profiling including three isotypes and multiplexing antigens is a useful and user-friendlier tool for screening pediatric populations to detect low viral load exposures among children, particularly while they are not vaccinated and vulnerable to highly contagious variants, and to recommend public health policies during pandemics

Genomic characterization of individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced lung cancer

Single nucleotide polymorphisms (SNPs) may modulate individual susceptibility to carcinogens. We designed a genome-wide association study to characterize individuals presenting extreme phenotypes of high and low risk to develop tobacco-induced non-small cell lung cancer (NSCLC), and we validated our results. We hypothesized that this strategy would enrich the frequencies of the alleles that contribute to the observed traits. We genotyped 2.37 million SNPs in 95 extreme phenotype individuals, that is: heavy smokers that either developed NSCLC at an early age (extreme cases); or did not present NSCLC at an advanced age (extreme controls), selected from a discovery set (n=3631). We validated significant SNPs in 133 additional subjects with extreme phenotypes selected from databases including >39,000 individuals. Two SNPs were validated: rs12660420 (p(combined)=5.66x10(-5); ORcombined=2.80), mapping to a noncoding transcript exon of PDE10A; and rs6835978 (p(combined)=1.02x10(-4); ORcombined=2.57), an intronic variant in ATP10D. We assessed the relevance of both proteins in early-stage NSCLC. PDE10A and ATP10D mRNA expressions correlated with survival in 821 stage I-II NSCLC patients (p=0.01 and p<0.0001). PDE10A protein expression correlated with survival in 149 patients with stage I-II NSCLC (p=0.002). In conclusion, we validated two variants associated with extreme phenotypes of high and low risk of developing tobacco-induced NSCLC. Our findings may allow to identify individuals presenting high and low risk to develop tobacco-induced NSCLC and to characterize molecular mechanisms of carcinogenesis and resistance to develop NSCLC