Another Green World?: Eno, Ireland and U2

This article explores a neglected area of popular music scholarship: the different aspects of auteur producer Brian Eno’s often complex relationship with Irish rock band, U2 and their home nation. It considers the cultural and political significance of Eno’s technical, aesthetic and philosophical innovations in his work with U2 in relation to wider debates about Irish cultural identity as articulated through music. It also explores how U2 and the Irish context may have reciprocally influenced aspects of Eno’s approach to artistic production. The article also seeks to situate these ideas within broader popular historical discourses that frame the Eno and U2 relationship

‘How Belfast got the blues’: Towards an alternative history

This article offers a revisionist history of a key period of Belfast and Northern Ireland’s music scene in the 1960s: the emergence of Them and Van Morrison and the attendant ‘legend’ of the group’s residency in the city’s Maritime Hotel. This formative moment is, somewhat surprisingly, under-explored in popular music studies, and the article seeks to address this relative absence. Van Morrison’s biographies are a vital resource here, and—via discourse analysis—we trace the emergence of a dominant narrative and assess its ideological implications, before moving on to analyse Them’s breakthrough single and related promotional materials. In so doing, we connect the scene that the group both emerged from and represented, to broader popular musical trends, as well as considering how the story of Them’s emergence is supported and framed in contemporary heritage initiatives. The article argues that the myth of Them, Morrison and the Maritime has obscured other ways of approaching the period, and we conclude with a counterhistory by considering an earlier blues/jazz scene in the city and how this might shape an orthodox narrative

The politician as performer : a practical and theoretical assessment

The following thesis examines the possibility that the contemporary Western political leader can be assessed and understood as a performer. It subsequently highlights the various repercussions of this statement, from theoretical, practical, historical and cultural perspectives. Through an extensive, multi-disciplinary literature review and case specific examples, the author argues that researching the politician as a performer has both practical and theoretical value. Included in this review are analyses of key contemporary issues surrounding political performance. The various uses of contemporary media, including the skills and semiotics that they generate, are discussed. Questions are raised regarding the audience's ability to interpret the information they receive through mediated performance. A working definition of audience is developed, to include those who consume and interpret political performance. Also explored in relation to political performance are questions of contemporary celebrity, performativity, and feminism. The thesis suggests that not only is the politician a performer, but that the related theories of performance have an impact on political dialogue at a variety of levels. As is highlighted in the thesis, existing literature has not examined the politician from this perspective. Therefore the work contributes to the body of knowledge around performance and cultural studies.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Low-dose carotid computed tomography angiography using pure iterative reconstruction

The aim of this study was to assess if a low-dose carotid computed tomography angiography (CTA) performed with pure iterative reconstruction (IR) is comparable to a conventional dose CTA protocol. Methods: Twenty patients were included. Radiation dose was divided into a low-dose acquisition reconstructed with pure IR and a conventional dose acquisition reconstructed with 40% hybrid IR. Dose, image noise, contrast resolution, spatial resolution, and carotid artery stenosis were measured. Results: Mean effective dose was significantly lower for low-dose than conventional dose studies (1.84 versus 3.71 mSv; P < 0.001). Subjective image noise, contrast resolution, and spatial resolution were significantly higher for the low-dose studies. There was excellent agreement for stenosis grading accuracy between low- and conventional dose studies (Cohen κ = 0.806). Conclusions: A low-dose carotid CTA protocol reconstructed with pure IR is comparable to a conventional dose CTA protocol in terms of image quality and diagnostic accuracy while enabling a dose reduction of 49.6%

A Unique Combination of Male Germ Cell miRNAs Coordinates Gonocyte Differentiation

The last 100 years have seen a concerning decline in male reproductive health associated with decreased sperm production, sperm function and male fertility. Concomitantly, the incidence of defects in reproductive development, such as undescended testes, hypospadias and testicular cancer has increased. Indeed testicular cancer is now recognised as the most common malignancy in young men. Such cancers develop from the pre-invasive lesion Carcinoma in Situ (CIS), a dysfunctional precursor germ cell or gonocyte which has failed to successfully differentiate into a spermatogonium. It is therefore essential to understand the cellular transition from gonocytes to spermatogonia, in order to gain a better understanding of the aetiology of testicular germ cell tumours. MicroRNA (miRNA) are important regulators of gene expression in differentiation and development and thus highly likely to play a role in the differentiation of gonocytes. In this study we have examined the miRNA profiles of highly enriched populations of gonocytes and spermatogonia, using microarray technology. We identified seven differentially expressed miRNAs between gonocytes and spermatogonia (down-regulated: miR-293, 291a-5p, 290-5p and 294*, up-regulated: miR-136, 743a and 463*). Target prediction software identified many potential targets of several differentially expressed miRNA implicated in germ cell development, including members of the PTEN, and Wnt signalling pathways. These targets converge on the key downstream cell cycle regulator Cyclin D1, indicating that a unique combination of male germ cell miRNAs coordinate the differentiation and maintenance of pluripotency in germ cells

The Hiyama Cross-Coupling Reaction: New Discoveries

In this account recent developments in the Hiyama cross-coupling reaction from 2010 up today are presented. The most important methodology involves formation of biaryl systems by using aryl bromides or iodides and aryl trialkoxy silanes: other variants are far less studied. The most useful procedures are collected paying special attention to the synthetic application of this methodology in synthetic organic chemistry.We thank the continuous financial support from our Ministerio de Ciencia e Innovación (MCINN; projects CTQ2007-62771/BQU, CTQ2010-20387, CONSOLIDER INGENIO 210-CDS2007-00006, CTQ2011-24151, CTQ2011-24165), the Ministerio de Economía y Competitividad (MINECO; projects CTQ2013-43446-P, CTQ2014-51912-REDC, CTQ2014-53695-P), FEDER, the Generalitat Valenciana (PROMETEO 2009/039, PROMETEOII/2014/017) and the University of Alicante

Measurement and interpretation of same-sign W boson pair production in association with two jets in pp collisions at s = 13 TeV with the ATLAS detector

This paper presents the measurement of fducial and diferential cross sections for both the inclusive and electroweak production of a same-sign W-boson pair in association with two jets (W±W±jj) using 139 fb−1 of proton-proton collision data recorded at a centre-of-mass energy of √s = 13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed by selecting two same-charge leptons, electron or muon, and at least two jets with large invariant mass and a large rapidity diference. The measured fducial cross sections for electroweak and inclusive W±W±jj production are 2.92 ± 0.22 (stat.) ± 0.19 (syst.)fb and 3.38±0.22 (stat.)±0.19 (syst.)fb, respectively, in agreement with Standard Model predictions. The measurements are used to constrain anomalous quartic gauge couplings by extracting 95% confdence level intervals on dimension-8 operators. A search for doubly charged Higgs bosons H±± that are produced in vector-boson fusion processes and decay into a same-sign W boson pair is performed. The largest deviation from the Standard Model occurs for an H±± mass near 450 GeV, with a global signifcance of 2.5 standard deviations