Contributing to becoming aware of the value of Open Education - An initiative of the IEEE Education Society

This paper shows the design, approach and first collection of data of the MOOC “Foundations to Open Education and OERs repositories”. This is the first MOOC of the IEEE Education Society, and it has been delivered freely and open available through IEEEx, a channel of edX

Education quality enhancement through open education adaptation.

Open Education is changing the educational paradigm. The consolidation of the OpenCourseWare initiative, supported by the top universities of the World, and the revolution generated in the recent years through the emergence of Massive Open Online Courses, present a new educational scenario for teachers, students and institutions. This new environment has furthered the use of e-learning, not only because of the benefits provided to students, such as flexibility of time and place, but also because anyone interested in training and learning, has access to a multitude of platforms with open resources and learning communities, not to mention the absence of admission processes or access requirements. The majority of times, this kind of courses will be the first contact between universities and students, which is of high importance regarding the prestige of the institutions. The formation of thousands and even hundreds of thousands of people brings a challenge to teachers and their institutions, as they must be able to offer a course with very high quality to satisfy such a large number of students. For this reason, teachers need to develop new skills, such as managing multimedia elements or mass forums, to get an appropriate course to be published. As institutions are the final image and responsible for the courses, they must establish a process to monitor, facilitate and advise teachers to get an excellent final result. This paper shows the adaptation process that a group of teachers have developed in order to publish a course in the OpenCourseWare platform of the Technical University of Madrid. In this case, these teachers and a group of experts from the institution worked as a team to enhance the course before publishing it. As a result, the satisfaction perceived by the students who used these new materials was increased, and the published course has received a large amount of visitors as an Open Educational Resource. One of the strategic lines of the Open Education Office of the Technical University of Madrid is to promote the creation of Massive Open Online Courses from OpenCourseWare courses. This paper shows the benefits from this initiative. At this moment, the same group of teachers is developing the publication of this course as a Massive Open Online Course and many materials and multimedia resources need to be created. Besides, a new course design will be necessary to adapt the methodology to the massive conditions of the new model. To this point, teachers' opinions have been collected, and after the performance of this hard process, students' satisfaction and quality of the course will be measured to analyze the final results

Rotación de personal y su relación con clima laboral de una empresa retail en Lima, 2021

La presente tesis tuvo como objetivo general determinar la relación de la rotación del personal y el clima laboral de una empresa retáil en Lima, 2021. El estudio fue empleado bajo el enfoque cuantitativo; con diseño no experimental – tipo aplicada – de corte transversal - correlacional y método cuantitativo. Así mismo, su muestra fue de 26 trabajadores utilizándose como instrumento el cuestionario para ambas variables. Asimismo, estos datos fueron implementados mediante ítems debidamente validados. Los resultados obtenidos están acompañados de tablas y gráficos. De esta manera demostraron una relación positiva fuerte según el estadístico de rho de spearman igual 0.820 entre la variable rotación del personal y clima laboral y se obtuvo un nivel de sig. 0.00 para ambas variables de estudio. Finalmente se concluye que la rotación del personal se relaciona con el clima laboral, es decir que su relación es significativa al haber constante rotación en el trabajo es el motivo de propiciar un excelente ambiente laboral. Se confirma que las 3 dimensiones del clima laboral tienen relación directa con la variable rotación del personal

Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets

The majority of today's antimicrobial therapeutics is derived from secondary metabolites produced by Actinobacteria. While it is generally assumed that less than 1% of Actinobacteria species from soil habitats have been cultivated so far, classic screening approaches fail to supply new substances, often due to limited throughput and frequent rediscovery of already known strains. To overcome these restrictions, we implement high-throughput cultivation of soil-derived Actinobacteria in microfluidic pL-droplets by generating more than 600000 pure cultures per hour from a spore suspension that can subsequently be incubated for days to weeks. Moreover, we introduce triggered imaging with real-time image-based droplet classification as a novel universal method for pL-droplet sorting. Growth-dependent droplet sorting at frequencies above 100 Hz is performed for label-free enrichment and extraction of microcultures. The combination of both cultivation of Actinobacteria in pL-droplets and real-time detection of growing Actinobacteria has great potential in screening for yet unknown species as well as their undiscovered natural products

Dampened predictable decadal North Atlantic climate fluctuations due to ice melting

The oscillatory behaviour of the climate system on decadal timescales before the instrumental record is hard to quantify. However, knowledge of this variability is important for putting current changes in context and for supporting reliable future predictions. Here we investigate the recurrent component of Holocene climate variability in the North Atlantic sector from 10,500 to 2,000 years ago by conducting a frequency analysis of both an annually laminated climate record from a lake in England and outputs from a long transient simulation of the Atlantic meridional overturning circulation. We find consistent decadal variability over the past 6,700 years and before 8,500 years before present, probably reflecting predominance of solar and ocean forcings. Between these dates, climate variability was dampened on decadal timescales. Our results suggest that meltwater discharge into the North Atlantic and the subsequent hydrographic changes, from the opening of the Hudson Bay until the final collapse of the Laurentide Ice Sheet, disrupted the decadal cyclic signals for more than a millennium. Given the current acceleration of the Greenland Ice Sheet melting in response to global warming, this study provides long-term evidence of potential challenges predicting future patterns of the climate syste

Comportamiento glucémico en los pacientes con enfermedad renal crónica en hemodiálisis mediante monitoria intermitente de glucosa capilar

Contexto: uso de monitoria intermitente de glucosa en pacientes que se encuentran en hemodiálisis. Objetivo: describir el comportamiento de la glucosa, mediante monitorización intermitente en pacientes con enfermedad renal crónica que se encuentran en hemodiálisis. Metodología: estudio observacional prospectivo. Se incluyeron pacientes con enfermedad renal crónica de diferentes causas que se encuentran en hemodiálisis. A su vez, se analizaron los resultados de las glucometrías antes y durante la sesión de hemodiálisis renal en 85 paciente hospitalizados, y posteriormente, se analizaron los valores de las glucometrías el día de hemodiálisis en 47 pacientes ambulatorios. Resultados: se incluyeron 132 pacientes con una mediana de edad de 61 años, 54.5% de sexo femenino, procedentes en gran parte de la ciudad de Neiva, Huila. El 93.9% tenían antecedentes de HTA; el 63.6% tenían anemia y el 53.8% diabetes mellitus, con un tiempo promedio de terapia de reemplazo renal de 3,05 años. El promedio de la glucometría al inicio de la hemodiálisis fue de 18,9 mg/dl mayor, respecto al valor postdiálisis entre los pacientes con diabetes, y solo de 14,0 mg/dl en los pacientes sin diabetes. Independientemente del antecedente de diabetes mellitus, el comportamiento de las glucometrías fue similar con valores más altos al inicio de la terapia observándose un descenso posterior con pocos registros de hipoglucemia. Conclusiones: en pacientes con enfermedad renal crónica que se encuentran en hemodiálisis el monitoreo intermitente de glucosa capilar, se evidencia un comportamiento en los valores de glucemia que muestran un descenso intradiálisis con elevación posterior al terminar la terapia de reemplazo renal

Why Chloroplasts and Mitochondria Contain Genomes

Chloroplasts and mitochondria originated as bacterial symbionts. The larger, host cells acquired genetic information from their prokaryotic guests by lateral gene transfer. The prokaryotically-derived genes of the eukaryotic cell nucleus now function to encode the great majority of chloroplast and mitochondrial proteins, as well as many proteins of the nucleus and cytosol. Genes are copied and moved between cellular compartments with relative ease, and there is no established obstacle to successful import of any protein precursor from the cytosol. Yet chloroplasts and mitochondria have not abdicated all genes and gene expression to the nucleus and to cytosolic translation. What, then, do chloroplast- and mitochondrially-encoded proteins have in common that confers a selective advantage on the cytoplasmic location of their genes? The proposal advanced here is that co-location of chloroplast and mitochondrial genes with their gene products is required for rapid and direct regulatory coupling. Redox control of gene expression is suggested as the common feature of those chloroplast and mitochondrial proteins that are encoded in situ. Recent evidence is consistent with this hypothesis, and its underlying assumptions and predictions are described

Valoración de la función sistólica del ventrículo derecho para la toma de decisiones en paciente intervenida de corrección de atresia pulmonar con comunicación interventricular y colaterales aortopulmonares

The prognosis of complex adult congenital heart disease has improved with the development of new imaging techniques for diagnosis and early treatment. The assessment of right ventricular systolic function with the new echo techniques has made important advances. The following case illustrates the importance of new techniques in the assessment of right systolic function after cardiac surgery.El pronóstico de las cardiopatías congénitas complejas del adulto ha mejorado con el desarrollo de las nuevas técnicas de imagen para el diagnóstico oportuno y tratamiento temprano. Asimismo, la valoración de la función sistólica del ventrículo derecho ha tenido importantes avances. El siguiente caso ilustra la importancia de las nuevas técnicas en la valoración de la función sistólica derecha tras la cirugía de un paciente con una cardiopatía congénita compleja

Comparative assessment of global irradiation from a satellite estimate model (CM SAF) and on-ground measurements (SIAR): a Spanish case study

An analysis and comparison of daily and yearly solar irradiation from the satellite CM SAF database and a set of 301 stations from the Spanish SIAR network is performed using data of 2010 and 2011. This analysis is completed with the comparison of the estimations of effective irradiation incident on three different tilted planes (fixed, two axis tracking, north-south hori- zontal axis) using irradiation from these two data sources. Finally, a new map of yearly values of irradiation both on the horizontal plane and on inclined planes is produced mixing both sources with geostatistical techniques (kriging with external drift, KED) The Mean Absolute Difference (MAD) between CM SAF and SIAR is approximately 4% for the irradiation on the horizontal plane and is comprised between 5% and 6% for the irradiation incident on the inclined planes. The MAD between KED and SIAR, and KED and CM SAF is approximately 3% for the irradiation on the horizontal plane and is comprised between 3% and 4% for the irradiation incident on the inclined planes. The methods have been implemented using free software, available as supplementary ma- terial, and the data sources are freely available without restrictions