3,749 research outputs found
A radio and infrared exploration of the Cygnus X-3 environments
To confirm, or rule out, the possible hot spot nature of two previously
detected radio sources in the vicinity of the Cygnus X-3 microquasar.
We present the results of a radio and near infrared exploration of the
several arc-minute field around the well known galactic relativistic jet source
Cygnus X-3 using the Very Large Array and the Calar Alto 3.5~m telescope.
The data this paper is based on do not presently support the hot spot
hypothesis. Instead, our new observations suggest that these sources are most
likely background or foreground objects. Actually, none of them appears to be
even barely extended as would be expected if they were part of a bow shock
structure. Our near infrared observations also include a search for extended
emission in the Bracket (2.166 m) and (2.122 m)
lines as possible tracers of shocked gas in the Cygnus X-3 surroundings. The
results were similarly negative and the corresponding upper limits are
reported.Comment: Accepted for publication in A&A; 5 pages, 4 figure
Chandra X-ray counterpart of KS 1741-293
We aim to investigate the nature of the high energy source KS 1741-293 by
revisiting the radio and infrared associations proposed in the early 1990s. Our
work is mostly based on the analysis of modern survey and archive data,
including the NRAO, MSX, 2MASS and Chandra archives, and catalogues. We also
have obtained deep CCD optical observations by ourselves. The coincidence of KS
1741-293 with an extended radio and far-infrared source, tentatively suggested
in 1994, is no longer supported by modern observational data. Instead, a
Chandra source is the only peculiar object found to be consistent with all
high-energy error circles of KS 1741-293 and we propose it to be its most
likely X-ray counterpart. We also report the existence of a non-thermal radio
nebula in the vicinity of the KS 1741-293 position with the appearance of a
supernova remnant. The possibility of being associated to this X-ray binary is
discussed.Comment: 5 pages, 4 figures, 2 tables. Accepted for publication in Astronomy &
Astrophysic
An X-ray study of the SNR G344.7-0.1 and the central object CXOU J170357.8-414302
Aims. We report results of an X-ray study of the supernova remnant (SNR)
G344.7-0.1 and the point-like X-ray source located at the geometrical center of
the SNR radio structure. Methods. The morphology and spectral properties of the
remnant and the central X-ray point-like source were studied using data from
the XMM-Newton and Chandra satellites. Archival radio data and infrared Spitzer
observations at 8 and 24 m were used to compare and study its multi-band
properties at different wavelengths. Results. The XMM-Newton and Chandra
observations reveal that the overall X-ray emission of G344.7-0.1 is extended
and correlates very well with regions of bright radio and infrared emission.
The X-ray spectrum is dominated by prominent atomic emission lines. These
characteristics suggest that the X-ray emission originated in a thin thermal
plasma, whose radiation is represented well by a plane-parallel shock plasma
model (PSHOCK). Our study favors the scenario in which G344.7-0.1 is a 6 x 10^3
year old SNR expanding in a medium with a high density gradient and is most
likely encountering a molecular cloud on the western side. In addition, we
report the discovery of a soft point-like X-ray source located at the
geometrical center of the radio SNR structure. The object presents some
characteristics of the so-called compact central objects (CCO). However, its
neutral hydrogen absorption column (N_{H}) is inconsistent with that of the
SNR. Coincident with the position of the source, we found infrared and optical
objects with typical early-K star characteristics. The X-ray source may be a
foreground star or the CCO associated with the SNR. If this latter possibility
were confirmed, the point-like source would be the farthest CCO detected so far
and the eighth member of the new population of isolated and weakly magnetized
neutron stars.Comment: 9 pages, 8 figures, accepted for publication in Astronomy and
Astrophysics. Higher resolution figures can be seen on A&
Selective Area Grown Semiconductor-Superconductor Hybrids: A Basis for Topological Networks
We introduce selective area grown hybrid InAs/Al nanowires based on molecular
beam epitaxy, allowing arbitrary semiconductor-superconductor networks
containing loops and branches. Transport reveals a hard induced gap and
unpoisoned 2e-periodic Coulomb blockade, with temperature dependent 1e features
in agreement with theory. Coulomb peak spacing in parallel magnetic field
displays overshoot, indicating an oscillating discrete near-zero subgap state
consistent with device length. Finally, we investigate a loop network, finding
strong spin-orbit coupling and a coherence length of several microns. These
results demonstrate the potential of this platform for scalable topological
networks among other applications.Comment: NBI QDEV 201
Obesity risk is associated with carbohydrate intake in women carrying the Gln27Glu beta2-adrenoceptor polymorphism.
Interindividual differences in the response to dietary intake are, in some cases, genotype dependent. Moreover, genotype-environment interactions may appear when the impact of lifestyle factors (e.g., diet) on a phenotype (e.g., BMI > 30 kg/m2) differs by genotype. A case-control study (obese subjects vs. normal weight controls) was conducted to assess a possible effect modification on obesity risk of the Gln27Glu polymorphism for the ß2-adrenoceptor gene depending on dietary intake. The sample included 159 subjects with BMI > 30 kg/m2 and 154 controls with BMI 49% energy (E)] had a higher obesity risk (OR = 2.56, P = 0.051). The product-term introduced in the logistic model to assess effect modification revealed a marginally significant interaction (P = 0.058) between both factors. Furthermore, a high intake of CHO (E > 49%) was associated with higher insulin levels among women carrying the Gln27Glu polymorphism (P < 0.01). This gene-nutrient interaction emphasizes the importance of examining the outcome of some obesity-related mutations depending on lifestyle (including diet) and may explain the heterogeneity of findings from previous studies
New MRI, 18F-DOPA and 11C-(+)-alpha-dihydrotetrabenazine templates for Macaca fascicularis neuroimaging: advantages to improve PET quantification
Normalization of neuroimaging studies to a stereotaxic space allows the utilization of standard volumes of
interest (VOIs) and voxel-based analysis (SPM). Such spatial normalization of PET and MRI studies requires a
high quality template image. The aim of this study was to create new MRI and PET templates of 18F-DOPA
and 11C-(+)-α-dihydrotetrabenazine (11C-DTBZ) of the Macaca fascicularis brain, an important animal
model of Parkinson's disease. MRI template was constructed as a smoothed average of the scans of 15
healthy animals, previously transformed into the space of one representative MRI. In order to create the PET
templates, 18F-DOPA and 11C-DTBZ PET of the same subjects were acquired in a dedicated small animal PET
scanner and transformed to the created MRI template space. To validate these templates for PET
quantification, parametric values obtained with a standard VOI-map applied after spatial normalization to
each template were statistically compared to results computed using individual VOIs drawn for each animal.
The high correlation between both procedures validated the utilization of all the templates, improving the
reproducibility of PET analysis. To prove the utility of the templates for voxel-based quantification, dopamine
striatal depletion in a representative monkey treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
(MPTP) was assessed by SPM analysis of 11C-DTBZ PET. A symmetric reduction in striatal 11C-DTBZ uptake
was detected in accordance with the induced lesion. In conclusion, templates of M. fascicularis brain have
been constructed and validated for reproducible and automated PET quantification. All templates are
electronically available via the internet
Autologous intramyocardial injection of cultured skeletal muscle-derived stem cells in patients with non-acute myocardial infarction
AIM: Experimental animal studies suggest that the use of skeletal myoblast in patients with myocardial infarction may result in improved cardiac function. The aim of the study was to assess the feasibility and safety of this therapy in patients with myocardial infarction.
METHODS AND RESULTS: Twelve patients with old myocardial infarction and ischaemic coronary artery disease underwent treatment with coronary artery bypass surgery and intramyocardial injection of autologous skeletal myoblasts obtained from a muscle biopsy of vastus lateralis and cultured with autologous serum for 3 weeks. Global and regional cardiac function was assessed by 2D and ABD echocardiogram. 18F-FDG and 13N-ammonia PET studies were used to determine perfusion and viability. Left ventricular ejection fraction (LVEF) improved from 35.5+/-2.3% before surgery to 53.5+/-4.98% at 3 months (P=0.002). Echocardiography revealed a marked improvement in regional contractility in those cardiac segments treated with skeletal myoblast (wall motion score index 2.64+/-0.13 at baseline vs 1.64+/-0.16 at 3 months P=0.0001). Quantitative 18F-FDG PET studies showed a significant (P=0.012) increased in cardiac viability in the infarct zone 3 months after surgery. No statistically significant differences were found in 13N-ammonia PET studies. Skeletal myoblast implant was not associated with an increase in adverse events. No cardiac arrhythmias were detected during early follow-up.
CONCLUSIONS: In patients with old myocardial infarction, treatment with skeletal myoblast in conjunction with coronary artery bypass is safe and feasible and is associated with an increased global and regional left ventricular function,improvement in the viability of cardiac tissue in the infarct area and no induction of arrhythmias
An Overview of the 2014 ALMA Long Baseline Campaign
A major goal of the Atacama Large Millimeter/submillimeter Array (ALMA) is to
make accurate images with resolutions of tens of milliarcseconds, which at
submillimeter (submm) wavelengths requires baselines up to ~15 km. To develop
and test this capability, a Long Baseline Campaign (LBC) was carried out from
September to late November 2014, culminating in end-to-end observations,
calibrations, and imaging of selected Science Verification (SV) targets. This
paper presents an overview of the campaign and its main results, including an
investigation of the short-term coherence properties and systematic phase
errors over the long baselines at the ALMA site, a summary of the SV targets
and observations, and recommendations for science observing strategies at long
baselines. Deep ALMA images of the quasar 3C138 at 97 and 241 GHz are also
compared to VLA 43 GHz results, demonstrating an agreement at a level of a few
percent. As a result of the extensive program of LBC testing, the highly
successful SV imaging at long baselines achieved angular resolutions as fine as
19 mas at ~350 GHz. Observing with ALMA on baselines of up to 15 km is now
possible, and opens up new parameter space for submm astronomy.Comment: 11 pages, 7 figures, 2 tables; accepted for publication in the
Astrophysical Journal Letters; this version with small changes to
affiliation
Search for muon-neutrino emission from GeV and TeV gamma-ray flaring blazars using five years of data of the ANTARES telescope
The ANTARES telescope is well-suited for detecting astrophysical transient
neutrino sources as it can observe a full hemisphere of the sky at all times
with a high duty cycle. The background due to atmospheric particles can be
drastically reduced, and the point-source sensitivity improved, by selecting a
narrow time window around possible neutrino production periods. Blazars, being
radio-loud active galactic nuclei with their jets pointing almost directly
towards the observer, are particularly attractive potential neutrino point
sources, since they are among the most likely sources of the very high-energy
cosmic rays. Neutrinos and gamma rays may be produced in hadronic interactions
with the surrounding medium. Moreover, blazars generally show high time
variability in their light curves at different wavelengths and on various time
scales. This paper presents a time-dependent analysis applied to a selection of
flaring gamma-ray blazars observed by the FERMI/LAT experiment and by TeV
Cherenkov telescopes using five years of ANTARES data taken from 2008 to 2012.
The results are compatible with fluctuations of the background. Upper limits on
the neutrino fluence have been produced and compared to the measured gamma-ray
spectral energy distribution.Comment: 27 pages, 16 figure
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