69 research outputs found
Predictors of choice of initial antifungal treatment in intraabdominal candidiasis
Intraabdominal candidiasis (IAC) is the second most frequent form of invasive candidiasis, and is associated with high mortality rates. This study aims to identify current practices in initial antifungal treatment (IAT) in a real-world scenario and to define the predictors of the choice of echinocandins or azoles in IAC episodes. Secondary analysis was performed of a multinational retrospective cohort at 13 teaching hospitals in four countries (Italy, Greece, Spain and Brazil), over a 3-year period (2011\u20132013). IAC was identified in 481 patients, 323 of whom received antifungal therapy (classified as the treatment group). After excluding 13 patients given amphotericin B, the treatment group was further divided into the echinocandin group (209 patients; 64.7%) and the azole group (101 patients; 32.3%). Median APACHE II scores were significantly higher in the echinocandin group (p 0.013), but IAT did not differ significantly with regard to the Candida species involved. Logistic multivariate stepwise regression analysis, adjusted for centre effect, identified septic shock (adjusted OR (aOR) 1.54), APACHE II > 15 (aOR 1.16) and presence in surgical ward at diagnosis (aOR 1.16) as the top three independent variables associated with an empirical echinocandin regimen. No differences in 30-day mortality were observed between groups. Echinocandin regimen was the first choice for IAT in patients with IAC. No statistical differences in mortality were observed between regimens, but echinocandins were administered to patients with more severe disease. Some disagreements were identified between current clinical guidelines and prescription of antifungals for IAC at the bedside, so further educational measures are required to optimize therapies
First Measurement of the W Boson Mass in Run II of the Tevatron
We present a measurement of the W boson mass using 200/pb of data collected
in pbar p collisions at sqrt(s) = 1.96 TeV by the CDF II detector at Run II of
the Fermilab Tevatron. With a sample of 63964 W -> e nu candidates and 51128 W
-> mu nu candidates, we measure M_W = (80413 +- 34 (stat) +- 34 (syst) = 80413
+- 48) MeV/c^2. This is the most precise single measurement of the W boson mass
to date.Comment: published version in PR
Search for New Particles Leading to Z+jets Final States in Collisions at TeV
We present the results of a search for new particles that lead to a \Z boson
plus jets in collisions at TeV using the Collider
Detector at Fermilab (CDF II). A data sample with a luminosity of 1.06 \ifb\
collected using \Z boson decays to and is used. We describe a
completely data-based method to predict the dominant background from
standard-model \Z+jet events. This method can be similarly applied to other
analyses requiring background predictions in multi-jet environments, as shown
when validating the method by predicting the background from +jets in \ttbar
production. No significant excess above the background prediction is observed,
and a limit is set using a fourth generation quark model to quantify the
acceptance. Assuming and using a leading-order
calculation of the cross section, quark masses below 268 \gev/c^2
are excluded at 95% confidence level.Comment: To be submitted to PR
Observation and Mass Measurement of the Baryon
We report the observation and measurement of the mass of the bottom, strange
baryon through the decay chain , where
, , and .
Evidence for observation is based on a signal whose probability of arising from
the estimated background is 6.6 x 10^{-15}, or 7.7 Gaussian standard
deviations. The mass is measured to be (stat.) (syst.) MeV/.Comment: Minor text changes for the second version. Accepted by Phys. Rev.
Let
Precise measurement of the top quark mass in the lepton+jets topology at CDF II
We present a measurement of the mass of the top quark from proton-antiproton
collisions recorded at the CDF experiment in Run II of the Fermilab Tevatron.
We analyze events from the single lepton plus jets final state (). The top quark mass is extracted
using a direct calculation of the probability density that each event
corresponds to the final state. The probability is a function of both
the mass of the top quark and the energy scale of the calorimeter jets, which
is constrained {\it in situ} by the hadronic boson mass. Using 167 events
observed in 955 pb of integrated luminosity, we achieve the single
most precise measurement of the top quark mass, 170.8 2.2 (stat.)
1.4 (syst.) GeV/.Comment: accepted by Phys. Rev. Let
Polarizations of J/psi and psi(2S) Mesons Produced in ppbar Collisions at 1.96 TeV
We have measured the polarizations of \jpsi and \psiprime mesons as
functions of their transverse momentum \pt when they are produced promptly in
the rapidity range with \pt \geq 5 \pgev. The analysis is performed
using a data sample with an integrated luminosity of about 800 \ipb collected
by the CDF II detector. For both vector mesons, we find that the polarizations
become increasingly longitudinal as \pt increases from 5 to 30 \pgev. These
results are compared to the predictions of nonrelativistic quantum
chromodynamics and other contemporary models. The effective polarizations of
\jpsi and \psiprime mesons from -hadron decays are also reported.Comment: 8 pages, 7 figures, published in Physical Review Letter
Search for resonant ttbar production in ppbar collisions at sqrt{s}=1.96 TeV
We report on a search for narrow-width particles decaying to a top and
antitop quark pair. The data set used in the analysis corresponds to an
integrated luminosity of 680 pb^{-1} collected with the Collider Detector at
Fermilab in Run II. We present 95% confidence level upper limits on the cross
section times branching ratio. Assuming a specific topcolor-assisted
technicolor production model, the leptophobic Z' with width
\Gamma_{Z'}=0.012M_{Z'}, we exclude the mass range M_{Z'} < 725 GeV/c^2 at the
95% confidence level.Comment: 7 pages, 3 figures. submitted to Phys. Rev. Let
Search for Doubly Charged Higgs Bosons with Lepton-Flavor-Violating Decays involving Tau Leptons
We search for pair production of doubly charged Higgs particles followed by
decays into electron-tau and muon-tau pairs using data (350 inverse picobarns)
collected from proton-antiproton collisions at 1.96 TeV by the CDF II
experiment. We search separately for cases where three or four final-state
leptons are detected, and combine results for exclusive decays to left-handed
electron-tau (muon-tau) pairs. We set a lower mass limit of 114 (112) GeV/cc at
the 95% confidence level for left-handed doubly charged Higgs
Measurement of the Inclusive Jet Cross Section at the Fermilab Tevatron p-pbar Collider Using a Cone-Based Jet Algorithm
We present a measurement of the inclusive jet cross section in p-pbar
collisions at sqrt{s}=1.96 TeV based on data collected by the CDF II detector
with an integrated luminosity of 1.13 fb^-1. The measurement was made using the
cone-based Midpoint jet clustering algorithm in the rapidity region of |y|<2.1.
The results are consistent with next-to-leading-order perturbative QCD
predictions based on recent parton distribution functions (PDFs), and are
expected to provide increased precision in PDFs at high parton momentum
fraction x. The results are also compared to the recent inclusive jet cross
section measurement using the k_T jet clustering algorithm, and we find that
the ratio of the cross sections measured with the two algorithms is in
agreement with theoretical expectations over a large range of jet transverse
momentum and rapidity.Comment: Phys. Rev. D 78, 052006 (2008). We are posting a new version of the
paper with corrections for minor errors in some of the figures and tables. It
should be noted that the data-theory comparison presented in the results
section (VIII) used the correct numbers, so the conclusions of the paper have
not changed. More details can be found in [1] of the pape
Measurement of the branching fraction and angular amplitudes
A search for the decay with is performed with 0.37 fb of collisions at
= 7 TeV collected by the LHCb experiment, finding a \Bs \to J\psi
K^-\pi^+ peak of signal events. The mass spectrum of
the candidates in the peak is dominated by the contribution.
Subtracting the non-resonant component, the branching fraction of
\BsJpsiKst is , where the first
uncertainty is statistical and the second systematic. A fit to the angular
distribution of the decay products yields the \Kst polarization fractions and
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