Um estudo topográfico da resposta comunitária ao incêndio na boate Kiss em Santa Maria, Brasil.

Este trabalho investiga as condições da resposta comunitária ao caso da boate Kiss, revisitadas através dos conteúdos da mídia local, o jornal A Razão e o Diário de Santa Maria. Esses dados são trabalhados por meio do Método de Análise de Conteúdo, sendo reorganizados mediante categorias e unidades temáticas que remetem aos locais de ocorrência e à natureza das formas de resposta. O período analisado vai desde o incêndio (2013) até o ano de 2019. Os locais mapeados foram o prédio daboate Kiss; o Centro Desportivo Municipal; as ruas; a Praça Saldanha Marinho; os Colégios Franciscano e Marista; o Gabinete do ExecutivoMunicipal (SUCV); a Câmara Municipal de Vereadores; o Ministério Público; e a Universidade Federal de Santa Maria (UFSM). As unidades temáticas identificadas referem-se ao momento de choque, à resposta imediata e às estratégias de enfrentamento. Esse mapeamento gerou uma proposição de espacialização representada em um mapa digitalinterativo.Este trabalho investiga as condições da resposta comunitária ao caso da boate Kiss, revisitadas através dos conteúdos da mídia local, o jornal A Razão e o Diário de Santa Maria. Esses dados são trabalhados por meio da Análise de Conteúdo, sendo reorganizados mediante categorias e unidades temáticas que remetem aos locais de ocorrência e a natureza das formas de resposta. O período analisado vai desde o incêndio até o ano de 2019. Os locais mapeados foram o Prédio da boate Kiss; o Centro Desportivo Municipal; as ruas; a Praça Saldanha Marinho; os Colégios Franciscano e Marista; o Gabinete do Executivo Municipal (SUCV); a Câmara Municipal de Vereadores; o Ministério Público; e a Universidade Federal de Santa Maria.  As unidades temáticas identificadas referem-se ao momento de choque, a resposta imediata e as estratégias de enfrentamento. Esse mapeamento gerou uma proposição de espacialização representada em um mapa digital interativo

Medidas de prevención de neumonías asociadas a la ventilación mecánica

Establish an adequate diagnosis of mechanical ventilation-associated pneumonia is one of the requirements most important and difficult in the care of patients in critical condition. The objective of this study was to evaluate the implementation of prevention measures of mechanical ventilation-associated pneumonia. Intensive care unit nursing staff. This research is located in the paradigm quantitative, positivist, non-experimental, descriptive supported with field design, cross. The population was 6 patients who nurses was low and care observation technique, is used as a tool for data collection; a list of matching, the implementation of measures for the prevention of pneumonia associated with mechanical ventilation through a list of statements to determine if it does or does not, i.e., with response dichotomous was recorded. The instrument consisting of 46 statements distributed in 4 dimensions. We conclude a large percentage complies with the application of the technique of hand-washing and runs properly the movement of patients so that they are more comfortable and his recovery is satisfactory, likewise, care pre intra and post aspiration of subglottic secretions and the oral cavity disinfection, a high percentage compliance with precautions and care in all phases, while in the changes of the circuits of the fan and the use of humidifiers pre vacuum circuits all comply with care.Establecer un diagnóstico adecuado de neumonía asociada a la ventilación mecánica es uno de los requisitos más importantes y difíciles en el cuidado de pacientes en estado crítico. El objetivo de este estudio fue evaluar la aplicación de medidas de prevención de neumonías asociadas a la ventilación mecánica por parte del personal de enfermería en una Unidad de Cuidados Intensivos. Metodologia: mediante una investigación descriptiva apoyada en un diseño de campo y de corte transversal. Los sujetos de estudio fueron 6 pacientes ingresados a la unidad a quienes el personal de enfermería realizaba cuidados, bajo observación y mediante una lista de cotejo con 46 enunciados se registró la aplicación por parte de las enfermeras de  medidas para la prevención de neumonías asociadas a la ventilación mecánica. Resultados: un gran porcentaje cumple la aplicación de la técnica de lavado de manos y ejecuta de manera correcta el movimiento de los pacientes para que estos estén más cómodos y su recuperación sea satisfactoria, así mismo, en los cuidados pre intra y post aspiración de secreciones subglóticas y desinfección de la cavidad oral, un alto porcentaje cumple con las precauciones y los cuidados en todas las fases, mientras que en los Cambios de los circuitos del ventilador y el uso de humidificadores pre aspiración. Conclusion: todas cumplen con los cuidados pautados para la prevencion de neumonias asociadas a la ventilacion mecanic

Single Charge Current in a Normal Mesoscopic Region Attached to Superconductor Leads via a Coupled Poisson Nonequilibrium Green Function Formalism

We study the I-V characteristic of mesoscopic systems or quantum dot (QD) attached to a pair of superconducting leads. Interaction effects in the QD are considered through the charging energy of the QD; that is, the treatment of current transport under a voltage bias is performed within a coupled Poisson nonequilibrium Green function (PNEGF) formalism. We derive the expression for the current in full generality but consider only the regime where transport occurs only via a single particle current. We show for this case and for various charging energies values U0 and associated capacitances of the QD the effect on the I-V characteristic. Also the influence of the coupling constants on the I-V characteristic is investigated. Our approach puts forward a novel interpretation of experiments in the strong Coulomb regime

Macrolide-Clarithromycin Task-Force for the Treatment and Prophylaxis of Covid-19 as a Single Agent

SARS-CoV-2 is a novel RNA coronavirus responsible of a deadly pandemic: the clinical illness COVID-19. With only one authorized drug for emergency use in critically ill patients: Remdesivir, there is not any other approved drug or vaccine yet with proven potential to overcome this infection. We exposed here many scientific evidences to support our novel idea that a macrolide, basically Clarithromycin, could be effective as a single agent for treatment and prophylaxis of COVID-19. Clarithromycin could change the history of this pandemic. It could reduce the costs of treatment and the potential adverse effects when combining more than one drug such as with Hydroxychloroquine. Clarithromycin treatment and prophylaxis as a single agent could be much more simple, safe and cheaper as giving Chloroquine or Hydroxychloroquine alone or in combination with Azithromycin as well as other therapeutic options.Fil: Mansilla, Eduardo. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaFil: Martínez, Ricardo Rangel. ExomePharma; MéxicoFil: Marin, Gustavo Horacio. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Médicas; ArgentinaFil: Filho, Idiberto Zotarelli. Faceres Medical School; BrasilFil: Rivas, Elsa. Hospital de la Amistad Perú - Corea San Rosa II; PerúFil: Rivas, Jaime. Hospital de la Amistad Perú - Corea San Rosa II; PerúFil: Carvalho, Katherine Athayde Teixeira de. Research Institute Pelé Little Prince; BrasilFil: Dayer, Mohammad Reza. Shahid Chamran University of Ahvaz; IránFil: Samadikuchaksaraei, Alí. Iran University of Medical Sciences; Irá

Lung epithelial signaling mediates early vaccine-induced CD4 + T cell activation and Mycobacterium tuberculosis control

Tuberculosis (TB) is one of the leading causes of death due to a single infectious agent. The development of a TB vaccine that induces durable and effective immunity to Mycobacterium tuberculosis

Racial Similarities in Response to Standardized Offer of Influenza Vaccination

Despite known benefits of influenza vaccination and coverage by Medicare Part B, elderly minority patients are less likely to receive influenza vaccination than whites. OBJECTIVES : To test whether a nonphysician-initiated standardized offer of influenza vaccination to all elderly primary care patients would result in similar proportions of African-American and white patients accepting vaccine. DESIGN : In 7 metropolitan Detroit primary care practices during the 2003 influenza vaccination season, medical assistants assessed influenza immunization status of all patients 65 years and older and collected limited demographic data. Eligible patients were offered vaccination. MEASUREMENTS : Proportion of patients accepting influenza vaccination by race and predictors of vaccine acceptance. RESULTS : Four hundred and fifty-four eligible patients with complete racial information were enrolled: 40% African American, 52% white, 8% other race/ethnicity. Similar proportions of African Americans and whites had already received the 2003 vaccine (11.6% and 11.0%, respectively) or stated vaccination as the reason for visit (23.8% and 30.5%, respectively). Among the remainder, there also were similar proportions who accepted vaccination: 68.9% white and 62.1% African-American patients. History of previous vaccination was the only statistically significant predictor of vaccine acceptance (odds ratio [OR] 8.64, 95% confidence interval [CI] 4.17, 17.91, P <.001). After adjusting for history of previous vaccination, age, gender, and education, the odds of vaccine acceptance were no different for whites and African Americans (OR 1.20, 95% CI 0.63, 2.29, P =.57). CONCLUSIONS : Vaccination acceptance differed little between African-American and white elderly patients. Using nonphysician personnel to identify and offer influenza vaccine to eligible patients is easily accomplished in primary care offices and has the potential to eliminate racial disparities in influenza vaccination.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/74908/1/j.1525-1497.2006.00401.x.pd

Observation of two new Ξb−\Xi_b^- baryon resonances

Two structures are observed close to the kinematic threshold in the $\Xi_b^0 \pi^-$ mass spectrum in a sample of proton-proton collision data, corresponding to an integrated luminosity of 3.0 fb$^{-1}$ recorded by the LHCb experiment. In the quark model, two baryonic resonances with quark content $bds$ are expected in this mass region: the spin-parity $J^P = \frac{1}{2}^+$ and $J^P=\frac{3}{2}^+$ states, denoted $\Xi_b^{\prime -}$ and $\Xi_b^{*-}$. Interpreting the structures as these resonances, we measure the mass differences and the width of the heavier state to be $m(\Xi_b^{\prime -}) - m(\Xi_b^0) - m(\pi^{-}) = 3.653 \pm 0.018 \pm 0.006$ MeV$/c^2$, $m(\Xi_b^{*-}) - m(\Xi_b^0) - m(\pi^{-}) = 23.96 \pm 0.12 \pm 0.06$ MeV$/c^2$, $\Gamma(\Xi_b^{*-}) = 1.65 \pm 0.31 \pm 0.10$ MeV, where the first and second uncertainties are statistical and systematic, respectively. The width of the lighter state is consistent with zero, and we place an upper limit of $\Gamma(\Xi_b^{\prime -}) < 0.08$ MeV at 95% confidence level. Relative production rates of these states are also reported.Comment: 17 pages, 2 figure

Measurement of the mass and lifetime of the Ωb−\Omega_b^- baryon

A proton-proton collision data sample, corresponding to an integrated luminosity of 3 fb$^{-1}$ collected by LHCb at $\sqrt{s}=7$ and 8 TeV, is used to reconstruct $63\pm9$ $\Omega_b^-\to\Omega_c^0\pi^-$, $\Omega_c^0\to pK^-K^-\pi^+$ decays. Using the $\Xi_b^-\to\Xi_c^0\pi^-$, $\Xi_c^0\to pK^-K^-\pi^+$ decay mode for calibration, the lifetime ratio and absolute lifetime of the $\Omega_b^-$ baryon are measured to be \begin{align*} \frac{\tau_{\Omega_b^-}}{\tau_{\Xi_b^-}} &= 1.11\pm0.16\pm0.03, \\ \tau_{\Omega_b^-} &= 1.78\pm0.26\pm0.05\pm0.06~{\rm ps}, \end{align*} where the uncertainties are statistical, systematic and from the calibration mode (for $\tau_{\Omega_b^-}$ only). A measurement is also made of the mass difference, $m_{\Omega_b^-}-m_{\Xi_b^-}$, and the corresponding $\Omega_b^-$ mass, which yields \begin{align*} m_{\Omega_b^-}-m_{\Xi_b^-} &= 247.4\pm3.2\pm0.5~{\rm MeV}/c^2, \\ m_{\Omega_b^-} &= 6045.1\pm3.2\pm 0.5\pm0.6~{\rm MeV}/c^2. \end{align*} These results are consistent with previous measurements.Comment: 11 pages, 5 figures, All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-008.htm

Study of B−→DK−π+π−B^{-}\to DK^-\pi^+\pi^- and B−→Dπ−π+π−B^-\to D\pi^-\pi^+\pi^- decays and determination of the CKM angle γ\gamma

We report a study of the suppressed $B^-\to DK^-\pi^+\pi^-$ and favored $B^-\to D\pi^-\pi^+\pi^-$ decays, where the neutral $D$ meson is detected through its decays to the $K^{\mp}\pi^{\pm}$ and CP-even $K^+K^-$ and $\pi^+\pi^-$ final states. The measurement is carried out using a proton-proton collision data sample collected by the LHCb experiment, corresponding to an integrated luminosity of 3.0~fb$^{-1}$. We observe the first significant signals in the CP-even final states of the $D$ meson for both the suppressed $B^-\to DK^-\pi^+\pi^-$ and favored $B^-\to D\pi^-\pi^+\pi^-$ modes, as well as in the doubly Cabibbo-suppressed $D\to K^+\pi^-$ final state of the $B^-\to D\pi^-\pi^+\pi^-$ decay. Evidence for the ADS suppressed decay $B^{-}\to DK^-\pi^+\pi^-$, with $D\to K^+\pi^-$, is also presented. From the observed yields in the $B^-\to DK^-\pi^+\pi^-$, $B^-\to D\pi^-\pi^+\pi^-$ and their charge conjugate decay modes, we measure the value of the weak phase to be $\gamma=(74^{+20}_{-19})^{\rm o}$. This is one of the most precise single-measurement determinations of $\gamma$ to date.Comment: 22 pages, 9 figures; All figures and tables, along with any supplementary material and additional information, are available at https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2015-020.htm