Long-term Multi-wavelength Observations of GRS 1758-258 and the ADAF Model

We present a long-term multi-wavelength light curve of Galactic black hole candidate GRS 1758-258 by combining previously published and archival data from GRANAT, ROSAT, CGRO, RXTE, SAX, ASCA, EXOSAT, and the VLA. In addition we include first spectral results from the balloon-borne Gamma-ray Arcminute Telescope Imaging System (GRATIS). In light of divergent analyses of the 1991-1993 ROSAT observations, we have re-analyzed these data; we find the soft X-rays track the hard X-rays, and that the fits require no black-body component-- indicating that GRS 1758-258 did not go to the high state in 1993. We offer an interpretation based on the ADAF model for a system with mdot \ltsim mdot_crit. We find the 1990-1993 coeval hard and soft X-ray observations support the ADAF predictions. We discuss a new way to constrain black-hole mass with spectral data and the ADAF theory, and apply this technique to GRS 1758-258 to find M_1 \gtsim 8--9 M_sol at an assumed distance of 8.5 kpc. Further investigations of the ADAF model allow us to evaluate the model critically against the data and flux-flux diagram of Barret, McClintock & Grindlay (1996) and to understand the limits of the latter's ``X-ray burster box.''Comment: 32 pp., AASTEX, 8 ps figures, accepted to Ap

Large-Mass Ultra-Low Noise Germanium Detectors: Performance and Applications in Neutrino and Astroparticle Physics

A new type of radiation detector, a p-type modified electrode germanium diode, is presented. The prototype displays, for the first time, a combination of features (mass, energy threshold and background expectation) required for a measurement of coherent neutrino-nucleus scattering in a nuclear reactor experiment. The device hybridizes the mass and energy resolution of a conventional HPGe coaxial gamma spectrometer with the low electronic noise and threshold of a small x-ray semiconductor detector, also displaying an intrinsic ability to distinguish multiple from single-site particle interactions. The present performance of the prototype and possible further improvements are discussed, as well as other applications for this new type of device in neutrino and astroparticle physics (double-beta decay, neutrino magnetic moment and WIMP searches).Comment: submitted to Phys. Rev.

A reliable system for quantitative g-protein activation imaging in cancer cells

Fluorescence resonance energy transfer (FRET) biosensors have proven to be an indispensable tool in cell biology and, more specifically, in the study of G-protein signalling. The best method of measuring the activation status or FRET state of a biosensor is often fluorescence lifetime imaging microscopy (FLIM), as it does away with many disadvantages inherent to fluorescence intensity-based methods and is easily quantitated. Despite the significant potential, there is a lack of reliable FLIM-FRET biosensors, and the data processing and analysis workflows reported previously face reproducibility challenges. Here, we established a system in live primary mouse pancreatic ductal adenocarcinoma cells, where we can detect the activation of an mNeonGreen-Gαi3-mCherry-Gγ2 biosensor through the lysophosphatidic acid receptor (LPAR) with 2-photon time-correlated single-photon counting (TCSPC) FLIM. This combination gave a superior signal to the commonly used mTurquoise2-mVenus G-protein biosensor. This system has potential as a platform for drug screening, or to answer basic cell biology questions in the field of G-protein signalling

SIGMA Observations of the Bursting Pulsar GRO J1744-28

We present the results of the GRANAT/SIGMA hard X-/soft gamma-ray long-term monitoring of the Galactic Center (GC) region concerning the source GRO J1744-28, discovered on 1995 Dec. 2 by CGRO/BATSE. SIGMA observed the region containing the source in 14 opportunities between 1990 and 1997. In two of these observing sessions, corresponding to March 1996 and March 1997, GRO J1744-28 was detected with a confidence level greater than 5(sigma) in the 35-75 keV energy band without detection in the 75-150 keV energy band. For the other sessions, upper limits of the flux are indicated. The particular imaging capabilities of the SIGMA telescope allow us to identify, specifically, the source position in the very crowded GC region, giving us a mean flux of (73.1 +/- 5.5)E-11 and (44.7 +/- 6.4)E-11 ergs cm^-2 s^-1 in the 35-75 keV energy band, for the March 1996 and March 1997 observing sessions, respectively. Combining the March 1997 SIGMA and BATSE observations, we found evidence pointing to the type-II nature of the source bursts for this period. For the same observing campaigns, spectra were obtained in the 35 to 150 keV energy band. The best fit corresponds to an optically thin thermal Bremsstrahlung with F(50 keV)=(3.6 +/- 0.6)E-4 phot cm^-2 s^-1 keV^-1 and kT(Bremss)=28 +/- 7 keV, for the first campaign, and F(50 keV)=(2.3 +/- 0.7)E-4 phot cm^-2 s^-1 keV^-1 and kT(Bremss)=18 (+12/-7) keV, for the second. This kind of soft spectrum is typical of binary sources containing a neutron star as the compact object, in contrast to the harder spectra typical of systems containing a black hole candidateComment: Accepted for publication in the Astrophysical Journal, 4 pages, 4 figure

BlackCAT: A catalogue of stellar-mass black holes in X-ray transients

During the last ~50 years, the population of black hole candidates in X-ray binaries has increased considerably with 59 Galactic objects detected in transient low-mass X-ray binaries, plus a few in persistent systems (including ~5 extragalactic binaries). We collect near-infrared, optical and X-ray information spread over hundreds of references in order to study the population of black holes in X-ray transients as a whole. We present the most updated catalogue of black hole transients, which contains X-ray, optical and near-infrared observations together with their astrometric and dynamical properties. It provides new useful information in both statistical and observational parameters providing a thorough and complete overview of the black hole population in the Milky Way. Analysing the distances and spatial distribution of the observed systems, we estimate a total population of ~1300 Galactic black hole transients. This means that we have already discovered less than ~5% of the total Galactic distribution. The complete version of this catalogue will be continuously updated online and in the Virtual Observatory, including finding charts and data in other wavelengths.Comment: http://www.astro.puc.cl/BlackCAT - Accepted for publication in Astronomy & Astrophysics. 20 pages, 8 figures, 5 Table

Hard X-ray sky survey with the SIGMA telescope aboard GRANAT observatory

During the lifetime of GRANAT orbital observatory the SIGMA telescope collected X-ray images of more than 1/4 of the whole sky. Among these regions the Galactic Center had largest exposure time (~9 million sec). In the present work we review all observations of the SIGMA telescope and present sensitivities achieved with it at different sky regionsComment: 6 pages, 5 figures. Accepted for publication in Astronomy Letter