427 research outputs found
Verifying Temporal Regular Properties of Abstractions of Term Rewriting Systems
The tree automaton completion is an algorithm used for proving safety
properties of systems that can be modeled by a term rewriting system. This
representation and verification technique works well for proving properties of
infinite systems like cryptographic protocols or more recently on Java Bytecode
programs. This algorithm computes a tree automaton which represents a (regular)
over approximation of the set of reachable terms by rewriting initial terms.
This approach is limited by the lack of information about rewriting relation
between terms. Actually, terms in relation by rewriting are in the same
equivalence class: there are recognized by the same state in the tree
automaton.
Our objective is to produce an automaton embedding an abstraction of the
rewriting relation sufficient to prove temporal properties of the term
rewriting system.
We propose to extend the algorithm to produce an automaton having more
equivalence classes to distinguish a term or a subterm from its successors
w.r.t. rewriting. While ground transitions are used to recognize equivalence
classes of terms, epsilon-transitions represent the rewriting relation between
terms. From the completed automaton, it is possible to automatically build a
Kripke structure abstracting the rewriting sequence. States of the Kripke
structure are states of the tree automaton and the transition relation is given
by the set of epsilon-transitions. States of the Kripke structure are labelled
by the set of terms recognized using ground transitions. On this Kripke
structure, we define the Regular Linear Temporal Logic (R-LTL) for expressing
properties. Such properties can then be checked using standard model checking
algorithms. The only difference between LTL and R-LTL is that predicates are
replaced by regular sets of acceptable terms
Interocular suppression prevents interference in a flanker task
Executive control of attention refers to processes that detect and resolve conflict among competing thoughts and actions. Despite the high-level nature of this faculty, the role of awareness in executive control of attention is not well understood. In this study, we used interocular suppression to mask the flankers in an arrow flanker task, in which the flankers and the target arrow were presented simultaneously in order to elicit executive control of attention. Participants were unable to detect the flanker arrows or to reliably identify their direction when masked. There was a typical conflict effect (prolonged reaction time and increased error rate under flanker-target incongruent condition compared to congruent condition) when the flanker arrows were unmasked, while the conflict effect was absent when the flanker arrows were masked with interocular suppression. These results suggest that blocking awareness of competing stimuli with interocular suppression prevents the involvement of executive control of attention
Microscopic theory of atom-molecule oscillations in a Bose-Einstein condensate
In a recent experiment at JILA [E.A. Donley et al., Nature (London) 417, 529
(2002)] an initially pure condensate of Rb-85 atoms was exposed to a specially
designed time dependent magnetic field pulse in the vicinity of a Feshbach
resonance. The production of new components of the gas as well as their
oscillatory behavior have been reported. We apply a microscopic theory of the
gas to identify these components and determine their physical properties. Our
time dependent studies allow us to explain the observed dynamic evolution of
all fractions, and to identify the physical relevance of the pulse shape. Based
on ab initio predictions, our theory strongly supports the view that the
experiments have produced a molecular condensate.Comment: 18 pages, 20 figure
Four small supernumerary marker chromosomes derived from chromosomes 6, 8, 11 and 12 in a patient with minimal clinical abnormalities: a case report
<p>Abstract</p> <p>Introduction</p> <p>Small supernumerary marker chromosomes are still a problem in cytogenetic diagnostic and genetic counseling. This holds especially true for the rare cases with multiple small supernumerary marker chromosomes. Most such cases are reported to be clinically severely affected due to the chromosomal imbalances induced by the presence of small supernumerary marker chromosomes. Here we report the first case of a patient having four different small supernumerary marker chromosomes which, apart from slight developmental retardation in youth and non-malignant hyperpigmentation, presented no other clinical signs.</p> <p>Case presentation</p> <p>Our patient was a 30-year-old Caucasian man, delivered by caesarean section because of macrosomy. At birth he presented with bilateral cryptorchidism but no other birth defects. At age of around two years he showed psychomotor delay and a bilateral convergent strabismus. Later he had slight learning difficulties, with normal social behavior and now lives an independent life as an adult. Apart from hypogenitalism, he has multiple hyperpigmented nevi all over his body, short feet with pes cavus and claw toes. At age of 30 years, cytogenetic and molecular cytogenetic analysis revealed a karyotype of 50,XY,+min(6)(:p11.1-> q11.1:),+min(8)(:p11.1->q11.1:),+min(11)(:p11.11->q11:),+min(12)(:p11.2~12->q10:), leading overall to a small partial trisomy in 12p11.1~12.1.</p> <p>Conclusions</p> <p>Including this case, four single case reports are available in the literature with a karyotype 50,XN,+4mar. For prenatally detected multiple small supernumerary marker chromosomes in particular we learn from this case that such a cytogenetic condition may be correlated with a positive clinical outcome.</p
Geologic Provinces Beneath the Greenland Ice Sheet Constrained by Geophysical Data Synthesis
Present understanding of Greenland's subglacial geology is derived mostly from interpolation of geologic mapping of its ice‐free margins and unconstrained by geophysical data. Here we refine the extent of its geologic provinces by synthesizing geophysical constraints on subglacial geology from seismic, gravity, magnetic and topographic data. North of 72°N, no province clearly extends across the whole island, leaving three distinct subglacial regions yet to be reconciled with margin geology. Geophysically coherent anomalies and apparent province boundaries are adjacent to the onset of faster ice flow at both Petermann Glacier and the Northeast Greenland Ice Stream. Separately, based on their subaerial expression, dozens of unusually long, straight and sub‐parallel subglacial valleys cross Greenland's interior and are not yet resolved by current syntheses of its subglacial topography
Mediation in the Law Curriculum
Cited by Lord Neuberger in ‘Educating Future Mediators’ at the 4th Civil Mediation Council National Conference, May 201
The globular cluster system of NGC1316. I. Wide-field photometry in the Washington system
NGC 1316 (Fornax A) is a prominent merger remnant in the outskirts of the
Fornax cluster. The cluster system has not yet been studied in its entirety. We
therefore present a wide-field study of the globular cluster system of NGC
1316, investigating its properties in relation to the global morphology of NGC
1316. We used the MOSAIC II camera at the 4-m Blanco telescope at CTIO in the
filters Washington C and Harris R. We identify globular cluster candidates and
study their color distribution and the structural properties of the system. In
an appendix, we also make morphological remarks, present color maps, and
present new models for the brightness and color profiles of the galaxy. The
cluster system is well confined to the optically visible outer contours of NGC
1316. The color distribution of the entire sample is unimodal, but the color
distribution of bright subsamples in the bulge shows two peaks that, by
comparison with theoretical Washington colors with solar metallicity,
correspond to ages of about 2 Gyr and 0.8 Gyr, respectively. We also find a
significant population of clusters in the color range 0.8 < C-R < 1.1 which
must be populated by clusters younger than 0.8 Gyr, unless they are very
metal-poor. The color interval 1.3 < C-R < 1.6 hosts the bulk of
intermediate-age clusters which show a surface density profile with a sharp
decline at about 4 arcmin. The outer cluster population shows an unimodal color
distribution with a peak at C-R=1.1, indicating a larger contribution of old,
metal-poor clusters. Their luminosity function does not show the expected
turn-over, so the fraction of younger clusters is still significant. Cluster
formation in NGC 1316 has continued after an initial burst, presumably related
to the main merger. A toy model with two bursts of ages 2 Gyr and 0.8 Gyr is
consistent with photometric properties and dynamical M/L-values.Comment: 19 pages, to appear in Astronomy and Astrophysics, abstract abridged,
format slightly different from the printed versio
Two Cases of Cardiac Arteriovenous Malformation Complicated by a Local Angioproliferative Process
Vascular malformations of the heart are extremely rare with only a few cases of the arteriovenous type of vascular malformation (AVM) reported. We investigated the pathology of two additional cases, which were complicated by the occurrence of a local vasoproliferative response of immature but benign vessels. We suppose that the mass forming effect of this vasoproliferative response, which has also been reported recently as a complication of congenital AVM elsewhere in the body, has significantly contributed to the onset of symptoms and ultimate death of both patients
Associations with photoreceptor thickness measures in the UK Biobank.
Spectral-domain OCT (SD-OCT) provides high resolution images enabling identification of individual retinal layers. We included 32,923 participants aged 40-69 years old from UK Biobank. Questionnaires, physical examination, and eye examination including SD-OCT imaging were performed. SD OCT measured photoreceptor layer thickness includes photoreceptor layer thickness: inner nuclear layer-retinal pigment epithelium (INL-RPE) and the specific sublayers of the photoreceptor: inner nuclear layer-external limiting membrane (INL-ELM); external limiting membrane-inner segment outer segment (ELM-ISOS); and inner segment outer segment-retinal pigment epithelium (ISOS-RPE). In multivariate regression models, the total average INL-RPE was observed to be thinner in older aged, females, Black ethnicity, smokers, participants with higher systolic blood pressure, more negative refractive error, lower IOPcc and lower corneal hysteresis. The overall INL-ELM, ELM-ISOS and ISOS-RPE thickness was significantly associated with sex and race. Total average of INL-ELM thickness was additionally associated with age and refractive error, while ELM-ISOS was additionally associated with age, smoking status, SBP and refractive error; and ISOS-RPE was additionally associated with smoking status, IOPcc and corneal hysteresis. Hence, we found novel associations of ethnicity, smoking, systolic blood pressure, refraction, IOPcc and corneal hysteresis with photoreceptor thickness
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