Update Frequency and Background Corpus Selection in Dynamic TF-IDF Models for First Story Detection

First Story Detection (FSD) requires a system to detect the very first story that mentions an event from a stream of stories. Nearest neighbour-based models, using the traditional term vector document representations like TF-IDF, currently achieve the state of the art in FSD. Because of its online nature, a dynamic term vector model that is incrementally updated during the detection process is usually adopted for FSD instead of a static model. However, very little research has investigated the selection of hyper-parameters and the background corpora for a dynamic model. In this paper, we analyse how a dynamic term vector model works for FSD, and investigate the impact of different update frequencies and background corpora on FSD performance. Our results show that dynamic models with high update frequencies outperform static model and dynamic models with low update frequencies; and that the FSD performance of dynamic models does not always increase with higher update frequencies, but instead reaches steady state after some update frequency threshold is reached. In addition, we demonstrate that different background corpora have very limited influence on the dynamic models with high update frequencies in terms of FSD performance

Tradescantia bioassays as monitoring systems for environmental mutagenesis: a review.

Since the early studies on the genetic effects of chemical and physical agents, species and clones of Tradescantia have been used as experimental subjects, by virtue of a series of favorable genetic characteristics. Bearing just six pairs (2n = 12) of large, easily observable chromosomes, cells from almost every part of the plant, from the root tips to the developing pollen tube, yield excellent material for cytogenetic studies. As a consequence of the intensive use of Tradescantia in genetic studies, a series of genetic characteristics have been found that offer opportunities for the detection of agents affecting the stability of the genome. At least five such characteristics have been selected as endpoints for the establishment of assays to evaluate mutagenesis. Three of these, root-tip mitosis, pollen-tube, and microspore mitosis are essentially chromosome aberration assays, wherein one observes and evaluates the visible damage in the chromosomes. A fourth, the stamen-hair mutation assay (Trad-SHM), is a point mutation mitotic assay based on the expression of a recessive gene for flower color in heterozygous plants. The fifth assay is a cytogenetic test based on the formation of micronuclei (Trad-MCN) that result from chromosome breakage in the meiotic pollen mother cells. This article examines the characteristics and fundamentals of the Trad-MCN and the Trad-SHM assays and reviews the results obtained to date with these systems in the assessment of environmental mutagenesis

Indifferentiated osteoclastic-type giant cell carcinoma

Initially described 40 years ago (Rosai), the undifferentiated osteoclastic-type giant cell carcinoma (IOGCC) is a variant of ductal adenocarcinoma and accounts for less than 1% of exocrine pancreatic tumors. Its extreme rarity, with consequent existence of few reports and clinical experience, leads to the arousal of doubts with regard to its histogenesis, types of approach and therapeutical attitudes. It is important to note that in Portugal no similar case is registered in medical literature. A 61 year old patient admitted to the Internal Medicine Ward 3 at Coimbra University Hospital presents with a volumous intra-abdominal mass in the left hypochondrium and microcytic anemia. During the investigation, a pancreatic neoplasm was identified, and the patient was submitted to surgical resection, the anatomo-pathological study of the tumor having revealed IOGCC. The particularities of the case, current available therapeutical options and its evolution are discussed, as well as a revision of the existing literature

Innovación en la administración municipal Tezoyuca 2009-2012.

En México en los últimos años se han promovido políticas de gobierno para revitalizar los espacios locales, con el fin de hacer más eficientes los procesos de gestión pública. Impulsando acciones de descentralización, bajo un marco institucional, que prepara espacios y condiciones para dar mayores posibilidades a la eficiencia gubernamental, desarrollo social y económico de los municipios. Sin embargo en la mayoría de los municipios, todavía se trabaja bajo esquemas de organización antiguos los cuales obstaculizan el desarrollo de las líneas de acción de la gestión municipal1. Los gobiernos locales municipales deben impulsar programas, acciones, estrategias y medidas que logren estructuras gubernamentales modernas e innovadoras que estén a la altura de los ciudadanos, de los retos del país y de los desafíos de un mundo global2. Por tanto deben ser capaces de promover el desarrollo, no solo a partir de los esquemas de gestión tradicional donde se impulsa la construcción de obras de bienestar público, prestación de servicios y también la promoción del del cambio y progreso global

Knowledge and attitude toward theranostics among Nuclear Medicine Technologists

This study was conducted to determine the knowledge and attitude of nuclear medicine technologists toward theranostics. This research utilized a quantitative correlational research design. Data were gathered from 69 practicing nuclear medicine technologists, specifically those that do not perform or have theranostics procedures. The data were gathered using a self-made questionnaire and statistically treated using frequency, percentage, range, mean, standard deviation, t-test, ANOVA, Kruskal-Wallis H test, Mann-Whitney U test, and Spearman Rank Order Correlation. Findings show that the majority of the respondents are male, and most are 20-30 years old. Most of the respondents have good knowledge and show a “positive attitude” toward theranostics. In general, there are no significant differences in the knowledge of the respondents about theranostics when they are grouped according to sex, years of experience and type of hospital they are currently employed in. However, there is a significant difference when grouped according to age, where the 31–40-year-old group showed a higher level of knowledge than the 20-30-year-old group possibly due to learning more about practices with theranostics. With the respondents’ attitude toward theranostics, there are no significant differences when they are grouped according to age, sex, years of experience, and type of hospital they are currently employed in. The findings also show that there is a weak positive relationship between the knowledge and attitude of the respondents toward theranostics. Generally, the results show that nuclear medicine technologists have very good attitude toward and good knowledge of theranostics

Client-Side Cornucopia : Comparing the Built-In Application Architecture Models in the Web Browser

Peer reviewe

Measuring impairments of functioning and health in patients with axial spondyloarthritis by using the ASAS Health Index and the Environmental Item Set : translation and cross-cultural adaptation into 15 languages

Introduction: The Assessments of SpondyloArthritis international society Health Index (ASAS HI) measures functioning and health in patients with spondyloarthritis (SpA) across 17 aspects of health and 9 environmental factors (EF). The objective was to translate and adapt the original English version of the ASAS HI, including the EF Item Set, cross-culturally into 15 languages. Methods: Translation and cross-cultural adaptation has been carried out following the forward-backward procedure. In the cognitive debriefing, 10 patients/country across a broad spectrum of sociodemographic background, were included. Results: The ASAS HI and the EF Item Set were translated into Arabic, Chinese, Croatian, Dutch, French, German, Greek, Hungarian, Italian, Korean, Portuguese, Russian, Spanish, Thai and Turkish. Some difficulties were experienced with translation of the contextual factors indicating that these concepts may be more culturally-dependent. A total of 215 patients with axial SpA across 23 countries (62.3% men, mean (SD) age 42.4 (13.9) years) participated in the field test. Cognitive debriefing showed that items of the ASAS HI and EF Item Set are clear, relevant and comprehensive. All versions were accepted with minor modifications with respect to item wording and response option. The wording of three items had to be adapted to improve clarity. As a result of cognitive debriefing, a new response option 'not applicable' was added to two items of the ASAS HI to improve appropriateness. Discussion: This study showed that the items of the ASAS HI including the EFs were readily adaptable throughout all countries, indicating that the concepts covered were comprehensive, clear and meaningful in different cultures

Protective effect of topical Cordia verbenacea in a rat periodontitis model: immune-inflammatory, antibacterial and morphometric assays

Background: This study evaluated the effects of C. verbenacea essential oil topically administered in a rat periodontitis model. Methods: Periodontitis was induced on rats in one of the mandibular first molars assigned to receive a ligature. Animals were randomly divided into two groups: a) non-treatment group (NT) (n = 18): animals received 1mL of vehicle; b) C. verbenacea group (C. v.) (n = 18): animals received 5mg/Kg of essential oils isolated from C. verbenacea. The therapies were administered topically 3 times daily for 11 days. Then, the specimens were processed for morphometric analysis of bone loss. The ligatures were used for microbiological assessment of the presence of Aggregatibacter actinomycetemcomitans, Tannerella forsythia and Porphyromonas gingivalis using PCR. The gingival tissue was collected to Elisa assay of interleukin (IL)-1 alpha and IL-10 levels. Results: Bone loss was inhibited by C. verbenacea when compared to the NT group (p < 0.05). A decrease in the levels of IL-1 alpha and increase in the IL-10 amounts was observed in the C. v. group as compared to NT group (p < 0.05). A lower frequency of P. gingivalis was found in C. v. group (p < 0.05). Conclusion: C. verbenacea essential oil topically administered diminished alveolar bone resorption, promoting a positive local imbalance in the pro/anti-inflammatory system and reducing the frequency of detection of P. gingivalis.1

Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, BASMI and mSASSS reference centile charts

The availability of population-specific normative data regarding disease severity measures is essential for patient assessment. The goals of the current study were to characterize the pattern of ankylosing spondylitis (AS) in Portuguese patients and to develop reference centile charts for BASDAI, BASFI, BASMI and mSASSS, the most widely used assessment tools in AS. AS cases were recruited from hospital outpatient clinics, with AS defined according to the modified New York criteria. Demographic and clinical data were recorded. All radiographs were evaluated by two independent experienced readers. Centile charts for BASDAI, BASFI, BASMI and mSASSS were constructed for both genders, using generalized linear models and regression models with duration of disease as independent variable. A total of 369 patients (62.3% male, mean ± (SD) age 45.4 ± 13.2 years, mean ± (SD) disease duration 11.4 ± 10.5 years, 70.7% B27-positive) were included. Family history of AS in a first-degree relative was reported in 17.6% of the cases. Regarding clinical disease pattern, at the time of assessment 42.3% had axial disease, 2.4% peripheral disease, 40.9% mixed disease and 7.1% isolated enthesopatic disease. Anterior uveitis (33.6%) was the most common extra-articular manifestation. The centile charts suggest that females reported greater disease activity and more functional impairment than males but had lower BASMI and mSASSS scores. Data collected through this study provided a demographic and clinical profile of patients with AS in Portugal. The development of centile charts constitutes a useful tool to assess the change of disease pattern over time and in response to therapeutic interventions

Influential publications in ecological economics revisited

International audienceWe revisit the analysis of Costanza et al. (2004, Ecological Economics) of influential publications in ecological economics to discover what has changed a decade on. We examine which sources have been influential on the field of ecological economics in the past decade, which articles in the journal Ecological Economics have had the most influence on the field and on the rest of science, and on which areas of science the journal is having the most influence. We find that the field has matured over this period, with articles published in the journal having a greater influence than before, an increase in citation links to environmental studies journals, a reduction in citation links to mainstream economics journals, and possibly a shift in themes to a more applied and empirical direction