31 research outputs found

    Mouse Chromosome 11

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/46996/1/335_2004_Article_BF00648429.pd

    Highly-parallelized simulation of a pixelated LArTPC on a GPU

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    The rapid development of general-purpose computing on graphics processing units (GPGPU) is allowing the implementation of highly-parallelized Monte Carlo simulation chains for particle physics experiments. This technique is particularly suitable for the simulation of a pixelated charge readout for time projection chambers, given the large number of channels that this technology employs. Here we present the first implementation of a full microphysical simulator of a liquid argon time projection chamber (LArTPC) equipped with light readout and pixelated charge readout, developed for the DUNE Near Detector. The software is implemented with an end-to-end set of GPU-optimized algorithms. The algorithms have been written in Python and translated into CUDA kernels using Numba, a just-in-time compiler for a subset of Python and NumPy instructions. The GPU implementation achieves a speed up of four orders of magnitude compared with the equivalent CPU version. The simulation of the current induced on 10^3 pixels takes around 1 ms on the GPU, compared with approximately 10 s on the CPU. The results of the simulation are compared against data from a pixel-readout LArTPC prototype

    Motion of the Diaphragm in Patients with Chronic Obstructive Pulmonary Disease While Spontaneously Breathing versus during Positive Pressure Breathing after Anaesthesia and Neuromuscular Blockage

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    Background: Diaphragmatic excursion during spontaneous ventilation (SV) in normal supine volunteers is greatest in the dependent regions (bottom). During positive pressure ventilation (PPV) after anesthesia and neuromuscular blockade and depending on tidal volume, the nondependent region (top) undergoes the greatest excursion, or the diaphragm moves uniformly. The purpose of this study was to compare diaphragmatic excursion (during SV and PPV) in patients with chronic obstructive pulmonary disease (COPD) with patients having normal pulmonary function. Methods: Twelve COPD patients and 12 normal control subjects were compared. Cross-table diaphragmatic fluoroscopy was performed while patients breathed spontaneously. After anesthetic induction and pharmacologic paralysis and during PPV, diaphragmatic fluoroscopy was repeated. For analytic purposes, the diaphragm was divided into three segments: top, middle, and bottom. Percentage of excursion of each segment during SV and PPV in normal subjects was compared with the percentage of excursion of each segment in patients with COPD. Results: There was no significant difference in the pattern of regional diaphragmatic excursion (as a percentage of total excursion)-top, middle, bottom-when comparing COPD patients with control subjects during SV and PPV. In the control subjects, regional diaphragmatic excursion was 16 ؎ (5), 33 ؎ (5), 51 ؎ (4) during SV and 49 ؎ (13), 32 ؎ (6), 19 ؎ (9) during PPV. In COPD patients, regional diaphragmatic excursion was 18 ؎ (7), 34 ؎ (5), 49 ؎ (7) during SV and 47 ؎ (10), 32 ؎ (6), 21 ؎ (9) during PPV

    Simulating the D/H ratio and atmospheric chemistry on Mars and comparing with NOMAD observations

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    The NOMAD instrument suite on the ESA-Roskosmos ExoMars Trace Gas Orbiter (TGO) observes the physical and chemical composition of the Martian atmosphere with highly resolved vertical profiles and nadir sounding in the IR and UV-vis domains. Vertically resolved profiles of many species (water vapor, HDO, ozone, CO, CO2, oxygen airglow, … ) and of dust and clouds were obtained for more than one Martian year [1-6]. In particular, the simultaneous detection of H2O and HDO in highly resolved profiles provide a unique dataset allowing to investigate present-day fractionation of water vapor on Mars [5]. We will provide simulations with the GEM-Mars General Circulation Model (GCM) [7-9] of HDO and the fractionation of water vapor upon cloud formation. The simulations will be compared in detail with the vertical profiles of the D/H ratio obtained from NOMAD observations. During its first year of operations, NOMAD witnessed the 2018 Global Dust Storm (GDS) during its onset, peak and decline. The redistribution of water vapor to high altitudes and latitudes observed during the GDS was explained using the GEM-Mars GCM [9]. The impact of the GDS on D/H can be estimated from these simulations, and is confirmed by the data. GEM-Mars also includes atmospheric chemistry calculations [8], and we compare these to several of the new observational datasets obtained by NOMAD. As the photolysis products of water vapor are a major driver for the atmospheric chemistry on Mars, the redistribution of water vapor over the atmosphere during the GDS is expected to have considerable impact on many other species. We present some results of the simulated impact of the GDS on atmospheric chemistry and on several of the observed species

    True micas

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    Mouse chromosome 11

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