332 research outputs found
Practical applications of sperm selection techniques for improving reproductive efficiency
Several selection techniques are available for processing spermatozoa. Apart from sperm washing to remove seminal plasma, only "swim-up" and colloid centrifugation have been used to any extent to prepare spermatozoa for in vitro fertilization, and only colloid centrifugation has been used to prepare sperm samples for artificial insemination. Single-layer centrifugation (SLC) through a species-specific colloid has been shown to be effective in selecting spermatozoa with good motility, normal morphology and intact chromatin in a range of species. This method is less timeconsuming than swim-up, and has been scaled-up to allow whole ejaculates to be processed in a practical manner. The applications of SLC are as follows: to improve sperm quality in insemination doses or in samples for in vitro fertilization, to increase the shelf life of normal sperm doses, to remove pathogens (viruses, bacteria), to improve cryosurvival by removing dead and dying spermatozoa before freezing or after thawing, to select spermatozoa for intracytoplasmic sperm injection, and to aid conservation breeding
Separating Hierarchical and General Hub Labelings
In the context of distance oracles, a labeling algorithm computes vertex
labels during preprocessing. An query computes the corresponding distance
from the labels of and only, without looking at the input graph. Hub
labels is a class of labels that has been extensively studied. Performance of
the hub label query depends on the label size. Hierarchical labels are a
natural special kind of hub labels. These labels are related to other problems
and can be computed more efficiently. This brings up a natural question of the
quality of hierarchical labels. We show that there is a gap: optimal
hierarchical labels can be polynomially bigger than the general hub labels. To
prove this result, we give tight upper and lower bounds on the size of
hierarchical and general labels for hypercubes.Comment: 11 pages, minor corrections, MFCS 201
Scarred Patterns in Surface Waves
Surface wave patterns are investigated experimentally in a system geometry
that has become a paradigm of quantum chaos: the stadium billiard. Linear waves
in bounded geometries for which classical ray trajectories are chaotic are
known to give rise to scarred patterns. Here, we utilize parametrically forced
surface waves (Faraday waves), which become progressively nonlinear beyond the
wave instability threshold, to investigate the subtle interplay between
boundaries and nonlinearity. Only a subset (three main types) of the computed
linear modes of the stadium are observed in a systematic scan. These correspond
to modes in which the wave amplitudes are strongly enhanced along paths
corresponding to certain periodic ray orbits. Many other modes are found to be
suppressed, in general agreement with a prediction by Agam and Altshuler based
on boundary dissipation and the Lyapunov exponent of the associated orbit.
Spatially asymmetric or disordered (but time-independent) patterns are also
found even near onset. As the driving acceleration is increased, the
time-independent scarred patterns persist, but in some cases transitions
between modes are noted. The onset of spatiotemporal chaos at higher forcing
amplitude often involves a nonperiodic oscillation between spatially ordered
and disordered states. We characterize this phenomenon using the concept of
pattern entropy. The rate of change of the patterns is found to be reduced as
the state passes temporarily near the ordered configurations of lower entropy.
We also report complex but highly symmetric (time-independent) patterns far
above onset in the regime that is normally chaotic.Comment: 9 pages, 10 figures (low resolution gif files). Updated and added
references and text. For high resolution images:
http://physics.clarku.edu/~akudrolli/stadium.htm
Geometric reduction in optimal control theory with symmetries
A general study of symmetries in optimal control theory is given, starting
from the presymplectic description of this kind of system. Then, Noether's
theorem, as well as the corresponding reduction procedure (based on the
application of the Marsden-Weinstein theorem adapted to the presymplectic case)
are stated both in the regular and singular cases, which are previously
described.Comment: 24 pages. LaTeX file. The paper has been reorganized. Additional
comments have been included in Section 3. The example in Section 5.2 has been
revisited. Some references have been adde
Combined constraints on modified Chaplygin gas model from cosmological observed data: Markov Chain Monte Carlo approach
We use the Markov Chain Monte Carlo method to investigate a global
constraints on the modified Chaplygin gas (MCG) model as the unification of
dark matter and dark energy from the latest observational data: the Union2
dataset of type supernovae Ia (SNIa), the observational Hubble data (OHD), the
cluster X-ray gas mass fraction, the baryon acoustic oscillation (BAO), and the
cosmic microwave background (CMB) data. In a flat universe, the constraint
results for MCG model are,
()
,
()
,
()
,
()
, and ()
.Comment: 12 pages, 1figur
On the k-Symplectic, k-Cosymplectic and Multisymplectic Formalisms of Classical Field Theories
The objective of this work is twofold: First, we analyze the relation between
the k-cosymplectic and the k-symplectic Hamiltonian and Lagrangian formalisms
in classical field theories. In particular, we prove the equivalence between
k-symplectic field theories and the so-called autonomous k-cosymplectic field
theories, extending in this way the description of the symplectic formalism of
autonomous systems as a particular case of the cosymplectic formalism in
non-autonomous mechanics. Furthermore, we clarify some aspects of the geometric
character of the solutions to the Hamilton-de Donder-Weyl and the
Euler-Lagrange equations in these formalisms. Second, we study the equivalence
between k-cosymplectic and a particular kind of multisymplectic Hamiltonian and
Lagrangian field theories (those where the configuration bundle of the theory
is trivial).Comment: 25 page
Observational constraint on generalized Chaplygin gas model
We investigate observational constraints on the generalized Chaplygin gas
(GCG) model as the unification of dark matter and dark energy from the latest
observational data: the Union SNe Ia data, the observational Hubble data, the
SDSS baryon acoustic peak and the five-year WMAP shift parameter. It is
obtained that the best fit values of the GCG model parameters with their
confidence level are ()
, ()
. Furthermore in this model, we can see that the
evolution of equation of state (EOS) for dark energy is similar to quiessence,
and its current best-fit value is with the confidence
level .Comment: 9 pages, 5 figure
Lorentz breaking Effective Field Theory and observational tests
Analogue models of gravity have provided an experimentally realizable test
field for our ideas on quantum field theory in curved spacetimes but they have
also inspired the investigation of possible departures from exact Lorentz
invariance at microscopic scales. In this role they have joined, and sometime
anticipated, several quantum gravity models characterized by Lorentz breaking
phenomenology. A crucial difference between these speculations and other ones
associated to quantum gravity scenarios, is the possibility to carry out
observational and experimental tests which have nowadays led to a broad range
of constraints on departures from Lorentz invariance. We shall review here the
effective field theory approach to Lorentz breaking in the matter sector,
present the constraints provided by the available observations and finally
discuss the implications of the persisting uncertainty on the composition of
the ultra high energy cosmic rays for the constraints on the higher order,
analogue gravity inspired, Lorentz violations.Comment: 47 pages, 4 figures. Lecture Notes for the IX SIGRAV School on
"Analogue Gravity", Como (Italy), May 2011. V.3. Typo corrected, references
adde
The exposure of the hybrid detector of the Pierre Auger Observatory
The Pierre Auger Observatory is a detector for ultra-high energy cosmic rays.
It consists of a surface array to measure secondary particles at ground level
and a fluorescence detector to measure the development of air showers in the
atmosphere above the array. The "hybrid" detection mode combines the
information from the two subsystems. We describe the determination of the
hybrid exposure for events observed by the fluorescence telescopes in
coincidence with at least one water-Cherenkov detector of the surface array. A
detailed knowledge of the time dependence of the detection operations is
crucial for an accurate evaluation of the exposure. We discuss the relevance of
monitoring data collected during operations, such as the status of the
fluorescence detector, background light and atmospheric conditions, that are
used in both simulation and reconstruction.Comment: Paper accepted by Astroparticle Physic
Low anti-staphylococcal IgG responses in granulomatosis with polyangiitis patients despite long-term Staphylococcus aureus exposure
Chronic nasal carriage of the bacterium Staphylococcus aureus in patients with the autoimmune disease granulomatosis with polyangiitis (GPA) is a risk factor for disease relapse. To date, it was neither known whether GPA patients show similar humoral immune responses to S. aureus as healthy carriers, nor whether specific S. aureus types are associated with GPA. Therefore, this study was aimed at assessing humoral immune responses of GPA patients against S. aureus antigens in relation to the genetic diversity of their nasal S. aureus isolates. A retrospective cohort study was conducted, including 85 GPA patients and 18 healthy controls (HC). Humoral immune responses against S. aureus were investigated by determining serum IgG levels against 59 S. aureus antigens. Unexpectedly, patient sera contained lower anti-staphylococcal IgG levels than sera from HC, regardless of the patients' treatment, while total IgG levels were similar or higher. Furthermore, 210 S. aureus isolates obtained from GPA patients were characterized by different typing approaches. This showed that the S. aureus population of GPA patients is highly diverse and mirrors the general S. aureus population. Our combined findings imply that GPA patients are less capable of mounting a potentially protective antibody response to S. aureus than healthy individuals
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