280 research outputs found

    Teachers’ Perceptions of Financial Literacy and the Implications for Professional Learning

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    Consumer, economic and financial literacy education at school is central to active and informed citizenship. Over the past decade, the Australian Securities and Investments Commission has led various policy initiatives and influenced curriculum and resource development in this area. However, there remains a paucity of research exploring how Australian teachers make sense of and approach their work as financial literacy educators or their professional learning needs and interests in this interdisciplinary field. This article reports research exploring practising teachers’ perceptions of the opportunities for financial literacy teaching and learning. Data were collected from 35 teachers in 16 Victorian primary schools. The findings suggest a need to educate teachers to: reflect upon the knowledge, skills and capabilities required to make informed financial decisions; identify and interpret the possibilities for financial literacy teaching and learning in the Australian Curriculum; and enact sophisticated pedagogical practice

    35-jährige Patientin mit generalisiertem Krampfanfall und nicht-kardiogenem Lungenödem nach Intoxikation

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    Zusammenfassung: Nach Intoxikation mit Verapamil-Retardpräparaten sind verzögerte und prolongierte kardiovaskuläre Nebenwirkungen bekannt. Wir berichten über 2 seltene Nebenwirkungen in Form eines generalisierten Krampfanfalls und eines nicht-kardiogenen Lungenödems, welche erst 13 bzw. 48h nach der Intoxikation aufgetreten sind. Aufgrund der verzögert auftretenden und prolongierten Arzneimittelwirkungen muss bei Intoxikationen mit retardierten Kalziumantagonisten die gastrointestinale Dekontamination mit antegrader Darmspülung und anschließender Aktivkohletherapie auch bei initial symptomfreien Patienten bis mindestens 24h nach Intoxikation gefordert werde

    Lymphogranuloma venereum: Eine alte Krankheit in neuem Kleid

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    Zusammenfassung: Lymphogranuloma venereum ist eine sexuell übertragene Erkrankung verursacht durch Chlamydia trachomatis der Serotypen L1, L2 und L3. Die klassische Manifestation ist eine schmerzhafte inguinale Lymphadenopathie, welche ohne Behandlung zu schwerwiegenden Komplikationen führt. Daneben wird seit einigen Jahren gehäuft eine ulzerierende Proktitis beschrieben, speziell bei Männern, die Sex mit Männern haben. Da die klinischen Beschwerden unspezifisch sind, muss bei Proktitis aktiv nach Chlamydia trachomatis gesucht werden. Die Diagnostik des Lymphogranuloma venereum erfolgt heute hauptsächlich mit molekularen Testverfahren. Zur Therapie wird Tetracyclin über 3Wochen empfohlen. Die Erkrankung wird anhand von 5 aktuellen klinischen Fallbeispielen dargestell

    Membrane-assisted enzymatic production of galactosyl-oligosaccharides from lactose in a continuous process

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    Functional foods such as oligosaccharides have attained significant acceptance in Japan and are attracting interest elsewhere. Beneficial physiological properties are attributed to oligosaccharides. Here, we describe the continuous production of oligosaccharides from a low-cost substrate (lactose) in a continuous membrane-assisted reactor (both polymeric and inorganic membranes were tested). Different enzymes, a number of feed concentrations, and different average residence times were investigated. The enzymes were used in their native form. Retention and recycling of the enzyme was successful, while the products together with some unreacted substrate and byproducts were removed as the ultrafiltration permeate. For the ultrafiltration, a steady-state flux of about 20 l/m2 hr was achieved. A maximum oligosaccharide concentration of over 40 %w/w was reached with an average residence time of 1 hr and a feed lactose concentration of 31 %w/w. Pilot scale experiments based on the laboratory tests are also reported

    Evolutionary Breakpoints in the Gibbon Suggest Association between Cytosine Methylation and Karyotype Evolution

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    Gibbon species have accumulated an unusually high number of chromosomal changes since diverging from the common hominoid ancestor 15–18 million years ago. The cause of this increased rate of chromosomal rearrangements is not known, nor is it known if genome architecture has a role. To address this question, we analyzed sequences spanning 57 breaks of synteny between northern white-cheeked gibbons (Nomascus l. leucogenys) and humans. We find that the breakpoint regions are enriched in segmental duplications and repeats, with Alu elements being the most abundant. Alus located near the gibbon breakpoints (<150 bp) have a higher CpG content than other Alus. Bisulphite allelic sequencing reveals that these gibbon Alus have a lower average density of methylated cytosine that their human orthologues. The finding of higher CpG content and lower average CpG methylation suggests that the gibbon Alu elements are epigenetically distinct from their human orthologues. The association between undermethylation and chromosomal rearrangement in gibbons suggests a correlation between epigenetic state and structural genome variation in evolution

    Extensive Copy-Number Variation of Young Genes across Stickleback Populations

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    MM received funding from the Max Planck innovation funds for this project. PGDF was supported by a Marie Curie European Reintegration Grant (proposal nr 270891). CE was supported by German Science Foundation grants (DFG, EI 841/4-1 and EI 841/6-1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

    A High-Resolution Map of Synteny Disruptions in Gibbon and Human Genomes

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    Gibbons are part of the same superfamily (Hominoidea) as humans and great apes, but their karyotype has diverged faster from the common hominoid ancestor. At least 24 major chromosome rearrangements are required to convert the presumed ancestral karyotype of gibbons into that of the hominoid ancestor. Up to 28 additional rearrangements distinguish the various living species from the common gibbon ancestor. Using the northern white-cheeked gibbon (2n = 52) (Nomascus leucogenys leucogenys) as a model, we created a high-resolution map of the homologous regions between the gibbon and human. The positions of 100 synteny breakpoints relative to the assembled human genome were determined at a resolution of about 200 kb. Interestingly, 46% of the gibbon–human synteny breakpoints occur in regions that correspond to segmental duplications in the human lineage, indicating a common source of plasticity leading to a different outcome in the two species. Additionally, the full sequences of 11 gibbon BACs spanning evolutionary breakpoints reveal either segmental duplications or interspersed repeats at the exact breakpoint locations. No specific sequence element appears to be common among independent rearrangements. We speculate that the extraordinarily high level of rearrangements seen in gibbons may be due to factors that increase the incidence of chromosome breakage or fixation of the derivative chromosomes in a homozygous state
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