219 research outputs found
Compactification and Supersymmetry Breaking in M-theory
Keeping N=1 supersymmetry in 4-dimension and in the leading order, we disuss
the various orbifold compactifications of M-theory suggested by Horava and
Witten on , , , and the compactification by
keeping singlets under symmetry, then the compactification
on . We also discuss the next to leading order K\"ahler potential,
superpotential, and gauge kinetic function in the case. In addition,
we calculate the SUSY breaking soft terms and find out that the universality of
the scalar masses will be violated, but the violation might be very small.Comment: 16 pages, latex, no figure
Compactifications of M-theory and their Phenomenological Consequences
We compactify the M-theory proposed by Horava and Witten on a Calabi-Yau
manifold with boundary . A no-scale-like K\"ahler potential, the
superpotential, and the gauge kinetic function are obtained in this
4-dimensional model. We also study the general phenomenological
consequences of the resulting M-theory-inspired model, which may include very
light gravitinos, axions and axinos.Comment: 10 pages, LaTe
Agroforestry systems of high natural and cultural value in Europe: structure, management, goods and services
info:eu-repo/semantics/publishedVersio
The effects of spatial resolution on Integral Field Spectrograph surveys at different redshifts. The CALIFA perspective
Over the past decade, 3D optical spectroscopy has become the preferred tool
for understanding the properties of galaxies and is now increasingly used to
carry out galaxy surveys. Low redshift surveys include SAURON, DiskMass,
ATLAS3D, PINGS and VENGA. At redshifts above 0.7, surveys such as MASSIV, SINS,
GLACE, and IMAGES have targeted the most luminous galaxies to study mainly
their kinematic properties. The on-going CALIFA survey () is the
first of a series of upcoming Integral Field Spectroscopy (IFS) surveys with
large samples representative of the entire population of galaxies. Others
include SAMI and MaNGA at lower redshift and the upcoming KMOS surveys at
higher redshift. Given the importance of spatial scales in IFS surveys, the
study of the effects of spatial resolution on the recovered parameters becomes
important. We explore the capability of the CALIFA survey and a hypothetical
higher redshift survey to reproduce the properties of a sample of objects
observed with better spatial resolution at lower redshift. Using a sample of
PINGS galaxies, we simulate observations at different redshifts. We then study
the behaviour of different parameters as the spatial resolution degrades with
increasing redshift.Comment: 20 pages, 16 figures. Accepted for publication in A&
CALIFA, the Calar Alto Legacy Integral Field Area survey: I. Survey presentation
We present here the Calar Alto Legacy Integral Field Area (CALIFA) survey,
which has been designed to provide a first step in this direction.We summarize
the survey goals and design, including sample selection and observational
strategy.We also showcase the data taken during the first observing runs
(June/July 2010) and outline the reduction pipeline, quality control schemes
and general characteristics of the reduced data. This survey is obtaining
spatially resolved spectroscopic information of a diameter selected sample of
galaxies in the Local Universe (0.005< z <0.03). CALIFA has been
designed to allow the building of two-dimensional maps of the following
quantities: (a) stellar populations: ages and metallicities; (b) ionized gas:
distribution, excitation mechanism and chemical abundances; and (c) kinematic
properties: both from stellar and ionized gas components. CALIFA uses the PPAK
Integral Field Unit (IFU), with a hexagonal field-of-view of
\sim1.3\sq\arcmin', with a 100% covering factor by adopting a three-pointing
dithering scheme. The optical wavelength range is covered from 3700 to 7000
{\AA}, using two overlapping setups (V500 and V1200), with different
resolutions: R\sim850 and R\sim1650, respectively. CALIFA is a legacy survey,
intended for the community. The reduced data will be released, once the quality
has been guaranteed. The analyzed data fulfill the expectations of the original
observing proposal, on the basis of a set of quality checks and exploratory
analysis.
We conclude from this first look at the data that CALIFA will be an important
resource for archaeological studies of galaxies in the Local Universe.Comment: 32 pages, 29 figures, Accepted for publishing in Astronomy and
Astrophysic
Executive Summary of the Topical Program: Nuclear Isomers in the Era of FRIB
We report on the Facility for Rare Isotope Beams (FRIB) Theory Alliance
topical program "Nuclear Isomers in the Era of FRIB". We outline the many ways
isomers influence and contribute to nuclear science and technology, especially
in the four FRIB pillars: properties of rare isotopes, nuclear astrophysics,
fundamental symmetries, and applications for the nation and society. We
conclude with a resolution stating our recommendation that the nuclear physics
community actively pursue isomer research. A white paper is forthcoming.Comment: 4 pages including reference
The Beta-decay Paul Trap Mk IV: Design and commissioning
The Beta-decay Paul Trap is an open-geometry, linear trap used to measure the
decays of Li and B to search for a tensor contribution to the weak
interaction. In the latest Li measurement of Burkey et al. (2022),
scattering was the dominant experimental systematic uncertainty. The Beta-decay
Paul Trap Mk IV reduces the prevalence of scattering by a factor of 4
through a redesigned electrode geometry and the use of glassy carbon and
graphite as electrode materials. The trap has been constructed and successfully
commissioned with Li in a new data campaign that collected 2.6 million
triple coincidence events, an increase in statistics by 30% with 4 times less
scattering compared to the previous Li data set.Comment: 17 pages, 7 figure
Low Dose Aerosol Fitness at the Innate Phase of Murine Infection Better Predicts Virulence amongst Clinical Strains of Mycobacterium tuberculosis
Background: Evaluation of a quick and easy model to determine the intrinsic ability of clinical strains to generate active TB has been set by assuming that this is linked to the fitness of Mycobacterium tuberculosis strain at the innate phase of the infection. Thus, the higher the bacillary load, the greater the possibility of inducting liquefaction, and thus active TB, once the adaptive response is set. Methodology/Principal Findings: The virulence of seven clinical Mycobacterium tuberculosis strains isolated in Spain was tested by determining the bacillary concentration in the spleen and lung of mice at weeks 0, 1 and 2 after intravenous (IV) inoculation of 10 4 CFU, and by determining the growth in vitro until the stationary phase had been reached. Cord distribution automated analysis showed two clear patterns related to the high and low fitness in the lung after IV infection. This pattern was not seen in the in vitro fitness tests, which clearly favored the reference strain (H37Rv). Subsequent determination using a more physiological low-dose aerosol (AER) inoculation with 10 2 CFU showed a third pattern in which the three best values coincided with the highest dissemination capacity according to epidemiological data. Conclusions/Significance: The fitness obtained after low dose aerosol administration in the presence of the innate immune response is the most predictive factor for determining the virulence of clinical strains. This gives support to a mechanism o
Morpho-kinematic properties of field S0 bulges in the CALIFA survey
We study a sample of 28 S0 galaxies extracted from the integral-field
spectroscopic (IFS) survey CALIFA. We combine an accurate two-dimensional (2D)
multi-component photometric decomposition with the IFS kinematic properties of
their bulges to understand their formation scenario. Our final sample is
representative of S0s with high stellar masses ().
They lay mainly on the red sequence and live in relatively isolated
environments similar to that of the field and loose groups. We use our 2D
photometric decomposition to define the size and photometric properties of the
bulges, as well as their location within the galaxies. We perform mock
spectroscopic simulations mimicking our observed galaxies to quantify the
impact of the underlying disc on our bulge kinematic measurements (
and ). We compare our bulge corrected kinematic measurements with the
results from Schwarzschild dynamical modelling. The good agreement confirms the
robustness of our results and allows us to use bulge reprojected values of
and . We find that the photometric ( and ) and
kinematic ( and ) properties of our field S0 bulges are not
correlated. We demonstrate that this morpho-kinematic decoupling is intrinsic
to the bulges and it is not due to projection effects. We conclude that
photometric diagnostics to separate different types of bulges (disc-like vs
classical) might not be useful for S0 galaxies. The morpho-kinematics
properties of S0 bulges derived in this paper suggest that they are mainly
formed by dissipation processes happening at high redshift, but dedicated
high-resolution simulations are necessary to better identify their origin.Comment: 31 pages, 19 figures. Accepted for publication in MNRA
A Global View of Cancer-Specific Transcript Variants by Subtractive Transcriptome-Wide Analysis
BACKGROUND: Alternative pre-mRNA splicing (AS) plays a central role in generating complex proteomes and influences development and disease. However, the regulation and etiology of AS in human tumorigenesis is not well understood. METHODOLOGY/PRINCIPAL FINDINGS: A Basic Local Alignment Search Tool database was constructed for the expressed sequence tags (ESTs) from all available databases of human cancer and normal tissues. An insertion or deletion in the alignment of EST/EST was used to identify alternatively spliced transcripts. Alignment of the ESTs with the genomic sequence was further used to confirm AS. Alternatively spliced transcripts in each tissue were then subtractively cross-screened to obtain tissue-specific variants. We systematically identified and characterized cancer/tissue-specific and alternatively spliced variants in the human genome based on a global view. We identified 15,093 cancer-specific variants of 9,989 genes from 27 types of human cancers and 14,376 normal tissue-specific variants of 7,240 genes from 35 normal tissues, which cover the main types of human tumors and normal tissues. Approximately 70% of these transcripts are novel. These data were integrated into a database HCSAS (http://202.114.72.39/database/human.html, pass:68756253). Moreover, we observed that the cancer-specific AS of both oncogenes and tumor suppressor genes are associated with specific cancer types. Cancer shows a preference in the selection of alternative splice-sites and utilization of alternative splicing types. CONCLUSIONS/SIGNIFICANCE: These features of human cancer, together with the discovery of huge numbers of novel splice forms for cancer-associated genes, suggest an important and global role of cancer-specific AS during human tumorigenesis. We advise the use of cancer-specific alternative splicing as a potential source of new diagnostic, prognostic, predictive, and therapeutic tools for human cancer. The global view of cancer-specific AS is not only useful for exploring the complexity of the cancer transcriptome but also widens the eyeshot of clinical research
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