897 research outputs found
The Geometry of Large Causal Diamonds and the No Hair Property of Asymptotically de-Sitter Spacetimes
In a previous paper we obtained formulae for the volume of a causal diamond
or Alexandrov open set whose duration is
short compared with the curvature scale. In the present paper we obtain
asymptotic formulae valid when the point recedes to the future boundary
of an asymptotically de-Sitter spacetime. The volume (at fixed
) remains finite in this limit and is given by the universal formula
plus
corrections (given by a series in ) which begin at order .
The coefficents of the corrections depend on the geometry of . This
behaviour is shown to be consistent with the no-hair property of cosmological
event horizons and with calculations of de-Sitter quasinormal modes in the
literature.Comment: 13 pages, 2 figures, Latex; references adde
Hepatosplenic Gamma/Delta T-Cell Lymphoma Masquerading as Alcoholic Hepatitis and Methadone Withdrawal
Hepatosplenic gamma/delta T-cell lymphoma is a rare neoplasm of mature gamma/delta T-cells with sinusoidal infiltration of spleen, liver, and bone marrow. Patients are predominantly adolescent and young adult males and usually present with marked hepatosplenomegaly. Pancytopenia is another common finding. Despite an initial response to treatment, patients have a median survival of one to two years. In this report, we document a case of alcoholic hepatitis and methadone withdrawal masquerading unsuspected, hepatosplenic gamma/delta T-cell lymphoma with unusual CD20 positivity
The gut wall's potential as a partner for precision oncology in immune checkpoint treatment
The gut wall is the largest immune organ and forms a barrier through which gut microbiota interact with the immune system in the rest of the body. Gut microbiota composition plays a role in the strength and timing of the anticancer immune response on immune checkpoint inhibitors (ICI). Surprisingly, the effects of gut wall characteristics, such as physical barrier integrity, permeability, and activity and composition of the intestinal immune system, on response to ICI has received little attention. Here, we provide an overview of markers to characterize the gut wall and interventions that can modulate these gut wall characteristics. Finally, we present a future perspective on how these gut wall markers and interventions might be utilized and studied to improve ICI treatment strategies
On Gauge Invariance of Breit-Wigner Propagators
We present an approach to bosonic () as well as fermionic
(top-quark) Breit-Wigner propagators which is consistent with gauge invariance
arguments. In particular, for the -boson propagator we extend previous
analyses and show that the part proportional to must be
modified near the resonance. We derive a mass shift which agrees with results
obtained elsewhere by different methods. The modified form of a resonant heavy
fermion propagator is also given.Comment: 16 p., TeX, (final version
Epidemic processes with immunization
We study a model of directed percolation (DP) with immunization, i.e. with
different probabilities for the first infection and subsequent infections. The
immunization effect leads to an additional non-Markovian term in the
corresponding field theoretical action. We consider immunization as a small
perturbation around the DP fixed point in d<6, where the non-Markovian term is
relevant. The immunization causes the system to be driven away from the
neighbourhood of the DP critical point. In order to investigate the dynamical
critical behaviour of the model, we consider the limits of low and high first
infection rate, while the second infection rate remains constant at the DP
critical value. Scaling arguments are applied to obtain an expression for the
survival probability in both limits. The corresponding exponents are written in
terms of the critical exponents for ordinary DP and DP with a wall. We find
that the survival probability does not obey a power law behaviour, decaying
instead as a stretched exponential in the low first infection probability limit
and to a constant in the high first infection probability limit. The
theoretical predictions are confirmed by optimized numerical simulations in 1+1
dimensions.Comment: 12 pages, 11 figures. v.2: minor correction
Quasiparticle Interactions in Fractional Quantum Hall Systems: Justification of Different Hierarchy Schemes
The pseudopotentials describing the interactions of quasiparticles in
fractional quantum Hall (FQH) states are studied. Rules for the identification
of incompressible quantum fluid ground states are found, based upon the form of
the pseudopotentials. States belonging to the Jain sequence nu=n/(1+2pn), where
n and p are integers, appear to be the only incompressible states in the
thermodynamic limit, although other FQH hierarchy states occur for finite size
systems. This explains the success of the composite Fermion picture.Comment: RevTeX, 10 pages, 7 EPS figures, submitted fo Phys.Rev.
Density functional method for nonequilibrium electron transport
We describe an ab initio method for calculating the electronic structure,
electronic transport, and forces acting on the atoms, for atomic scale systems
connected to semi-infinite electrodes and with an applied voltage bias. Our
method is based on the density functional theory (DFT) as implemented in the
well tested Siesta approach (which uses non-local norm-conserving
pseudopotentials to describe the effect of the core electrons, and linear
combination of finite-range numerical atomic orbitals to describe the valence
states). We fully deal with the atomistic structure of the whole system,
treating both the contact and the electrodes on the same footing. The effect of
the finite bias (including selfconsistency and the solution of the
electrostatic problem) is taken into account using nonequilibrium Green's
functions. We relate the nonequilibrium Green's function expressions to the
more transparent scheme involving the scattering states. As an illustration,
the method is applied to three systems where we are able to compare our results
to earlier ab initio DFT calculations or experiments, and we point out
differences between this method and existing schemes. The systems considered
are: (1) single atom carbon wires connected to aluminum electrodes with
extended or finite cross section, (2) single atom gold wires, and finally (3)
large carbon nanotube systems with point defects.Comment: 18 pages, 23 figure
Landau-Zener-Stuckelberg interferometry
A transition between energy levels at an avoided crossing is known as a
Landau-Zener transition. When a two-level system (TLS) is subject to periodic
driving with sufficiently large amplitude, a sequence of transitions occurs.
The phase accumulated between transitions (commonly known as the Stuckelberg
phase) may result in constructive or destructive interference. Accordingly, the
physical observables of the system exhibit periodic dependence on the various
system parameters. This phenomenon is often referred to as
Landau-Zener-Stuckelberg (LZS) interferometry. Phenomena related to LZS
interferometry occur in a variety of physical systems. In particular, recent
experiments on LZS interferometry in superconducting TLSs (qubits) have
demonstrated the potential for using this kind of interferometry as an
effective tool for obtaining the parameters characterizing the TLS as well as
its interaction with the control fields and with the environment. Furthermore,
strong driving could allow for fast and reliable control of the quantum system.
Here we review recent experimental results on LZS interferometry, and we
present related theory.Comment: 34 single-column pages, 11 figure
Electronic transport in extended systems: Application to carbon nanotubes
Article on electronic transport in extended systems and the application to carbon nanotubes
Search for Single Top Production at LEP
Single top production in e+e- annihilations is searched for in data collected
by the L3 detector at centre-of-mass energies from 189 to 209 GeV,
corresponding to a total integrated luminosity of 634 pb-1. Investigating
hadronic and semileptonic top decays, no evidence of single top production at
LEP is obtained and upper limits on the single top cross section as a function
of the centre-of-mass energy are derived. Limits on possible anomalous
couplings, as well as on the scale of contact interactions responsible for
single top production are determined
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