New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms

Residential schools in Canada : survivor truths, access to records, and the post-TRC era

Dr. Logan is a Métis scholar with more than 20 years of experience working with elders and leaders in First Nations, Métis and Inuit communities in Canada. Prior to her time at UBC, Dr. Logan was the Manager of Research at the National Centre for Truth and Reconciliation at the University of Manitoba. She has held roles at the National Centre for Truth and Reconciliation, the Canadian Museum for Human Rights, the Métis Centre at the National Aboriginal Health Organization, the Aboriginal Healing Foundation, and the Legacy of Hope Foundation. Dr. Logan has worked with survivors of residential schools, completed research on the Métis experience in residential schools, and worked with Métis communities on a Michif language revitalization project.Arts, Faculty ofCritical Indigenous Studies, Institute forUnreviewedFacult

Valley of the Birdtail : An Indian Reserve, a White Town, and the Road to Reconciliation collection

Andrew Stobo Sniderman is a writer, lawyer and Rhodes Scholar. His profile of Canada’s Truth and Reconciliation Commission on Residential Schools won the award for best print feature from the Canadian Association of Journalists. Mr. Sniderman has argued before the Supreme Court of Canada, served as the human rights policy advisor to the Canadian Minister of Foreign Affairs, and worked for a judge of South Africa’s Constitutional Court. Prof. Sanderson is Beaver Clan, from the Opaskwayak Cree Nation. He is deeply engaged in Aboriginal issues from a policy perspective. He was a Senior Advisor to the Government of Ontario. His research areas include Aboriginal and Indigenous legal theory, as well as private law and public and private legal theory. Mr. Sniderman and Prof. Sanderson wrote the award winning book Valley of the Birdtail: An Indian Reserve, a White Town, and the Road to Reconciliation (2022), winner of two awards in 2023: The Stubbendieck Great Plains Distinguished Book Prize from the University of Nebraska-Lincoln Center for Great Plains Studies, and the J.W. Dafoe Book Prize; it was also a finalist for the 2023 Shaughnessy Cohen Prize for Political Writing.Arts, Faculty ofNon UBCCritical Indigenous Studies, Institute forUnreviewedFacultyOthe

Metis History and Experience and Residential Schools in Canada

A report foregrounding the experiences of Metis children in residential schools, and the issues they have faced and continue to face as a result

Students' participation in collaborative research should be recognised

Letter to the editor