395 research outputs found

    Utilisation du Stroop émotion pour l'étude de l'effet du vieillissement sur l'attention sélective

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    RĂ©sumĂ© : La psychologie cognitive s'intĂ©resse depuis quelques annĂ©es Ă  un effet de positivitĂ© qui semble apparaĂźtre avec l'avancement en Ăąge. Cet effet serait Ă©galement liĂ© Ă  la diminution, voire la disparition, d'un biais attentionnel nĂ©gatif, naturellement prĂ©sent chez les jeunes adultes. Celui-ci consiste en une plus grande perturbation de l'attention sĂ©lective en prĂ©sence de stimuli nĂ©gatifs. Une tĂąche cognitive d'attention sĂ©lective trĂšs utilisĂ©e pour Ă©tudier ce biais cognitif est le Stroop Ă©motion. PrĂ©sentant des mots Ă  valence nĂ©gative, positive et neutre, il permet de vĂ©rifier l'effet d'interfĂ©rence que produisent ces stimuli sur la capacitĂ© d'inhibition. Jusqu'Ă  prĂ©sent, les rares Ă©tudes utilisant le Stroop Ă©motion auprĂšs d'une population ĂągĂ©e sans trouble cognitif ne prĂ©sentent pas de consensus permettant de statuer clairement sur la modification de ce biais cognitif dans le vieillissement. La prĂ©sente Ă©tude proposait d'utiliser le Stroop Ă©motion pour observer l'effet du vieillissement sur l'attention sĂ©lective, en rĂ©pondant aux principales recommandations mĂ©thodologiques tirĂ©es des Ă©tudes prĂ©cĂ©dentes. Il Ă©tait attendu que les ĂągĂ©s ne devaient pas prĂ©senter d'effet d'interfĂ©rence en rĂ©ponse aux stimuli nĂ©gatifs, contrairement aux jeunes adultes. Les rĂ©sultats obtenus ont toutefois rĂ©vĂ©lĂ© la prĂ©sence d'un biais attentionnel nĂ©gatif tant chez les ĂągĂ©s que chez les jeunes adultes. L'interprĂ©tation de ces performances est discutĂ©e en regard des exigences cognitives du Stroop Ă©motion. Il pourrait ainsi ĂȘtre plus facile de mettre en Ă©vidence la diminution du biais attentionnel nĂ©gatif Ă  l'aide d'une prĂ©sentation diffĂ©rente des stimuli qui permettrait la mise en place de l'effet de positivitĂ© chez les ĂągĂ©s.||Abstract : For some years now, cognitive psychology has taken an interest in a positivity effect that appears with increased age. This effect is claimed to be related to the decrease in, or even disappearance of, a negative attentional bias that is naturally present in young adults; this effect consists in a greater disruption of selective attention in the presence of negative stimuli. A cognitive task measuring selective attention that is often used to study this cognitive bias is the emotional Stroop test. This task presents words with negative, positive and neutral valence and tests how these stimuli interfere with inhibition capacity. To date, the few studies that have used the emotional Stroop in an elderly population without cognitive disorders have not produced a consensus that would give us a clear sense of the change in this cognitive bias with aging. This study proposed to use the emotional Stroop to observe the effect of aging on selective attention by following the main methodological recommendations arising from earlier studies. It was expected that elderly people would not present an interference effect in response to negative stimuli, unlike young adults. However, the results revealed a negative attentional bias in both older and younger adults. This finding is interpreted in relation to the cognitive demands of the emotional Stroop. It could therefore be easier to highlight the decrease in negative attentional bias by using a different method of presenting stimuli, which would reveal the positivity effect in elderly people

    Improving The Effectiveness Of Human Resources Practices Through Transforming Care At The Bedside

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    In 2010, in an effort to increase patient involvement in decision-making about health care redesign, a Quebec university health care organization implemented the Transforming Care at the Bedside (TCAB). This article presents the results from a qualitative study exploring health professionals’ perceptions of TCAB and the effect on turnover and overtime. This descriptive, qualitative study utilized focus groups, individual interviews, and a review of administrative documents for data collection. Participants included hospital workers from five units implementing TCAB. The data generated by the interviews and focus groups were analyzed using NVivo with the method proposed by Miles and Huberman (1994). During the first year of implementation of TCAB, the team noted the importance of taking time to see the effects of the changes and thereby facilitate the involvement of other team members. A number of TCAB team members also cited communication as a facilitating element for informing team members of changes. According to the participants, the TCAB strategies that were implemented have had a positive impact on practice and on the work environment, and turnover showed an improvement. There was no change in absenteeism. TCAB has the potential to impact not only nurses’ work, but interprofessional team work as well, through changes that involve everyone. Future research should focus on how to support team members to reduce resistance to change and increase social support in order to implement and sustain changes.

    Demogenetic study of three populations within a region with strong founder effects

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    Objectives: The population of the Saguenay-Lac-St-Jean (SLSJ) region (Quebec, Canada) is known to have a relatively high prevalence of certain hereditary disorders, which can be explained by the consequences of founder effects. This study aims at providing new insights on the origins and subregional stratification of these founder effects. Methods: The genealogies of 300 individuals were reconstructed and analyzed using the BALSAC population register. Results: Inbreeding and kinship levels are higher in Lower Saguenay than in Upper Saguenay and Lac-St-Jean. The population of Lower Saguenay also distinguishes itself because of a fewer number of distinct ancestors. Conclusion: Beyond the genetic features that characterize the whole region, SLSJ also displays intraregional variability. Thus it is important to take into account the settlement patterns and the demographic history of this population for a better appraisal of its contemporary genetic structure

    HCO3 dependent impact of Na+,K+, 2Cl cotransport in vascular smooth muscle excitation-contraction coupling

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    In smooth muscles, inhibition of Na(+),K(+),2Cl(-) cotransport (NKCC) by bumetanide decreased intracellular Cl(-) content ([Cl(-)](i)) and suppressed the contractions triggered by diverse stimuli. This study examines whether or not bicarbonate, a regulator of several Cl(-) transporters, affects the impact of NKCC in excitation-contraction coupling. Addition of 25 mM NaHCO(3) attenuated the inhibitory action of bumetanide on mesenteric artery contractions evoked by 30 mM KCl and phenylephrine (PE) by 5 and 3-fold, respectively. In cultured vascular smooth muscle cells, NaHCO(3) almost completely abolished inhibitory actions of bumetanide on transient depolarization and [Ca(2+)](i) elevation triggered by PE. In bicarbonate-free medium, bumetanide decreased [Cl(-)](i) by approximately 15%; this effect was almost totally abrogated by NaHCO(3). The addition of NaHCO(3) resulted in 2-fold inhibition of NKCC activity and 3-fold attenuation of [Cl(-)](i). These data strongly suggest that extracellular HCO(3)(-) diminishes the NKCC-sensitive component of excitation-contraction coupling via suppression of this carrier

    Becoming a research participant : decision-making needs of individuals with neuromuscular diseases

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    BACKGROUND: Research has shown that some people with neuromuscular diseases may have a lower level of education due to lower socioeconomic status and possibly compromised health literacy. In view of these data, it appears important to document their decision-making needs to ensure better support when faced with the decision to participate or not in research projects. OBJECTIVES: 1) To document the decision-making needs of individuals with neuromuscular diseases to participate in research; 2) To explore their preferences regarding the format of knowledge translation tools related to research participation. METHODS: This qualitative study is based on the Ottawa Decision Support Framework. A two-step descriptive study was conducted to capture the decision-making needs of people with neuromuscular diseases related to research participation: 1) Individual semi-directed interviews (with people with neuromuscular diseases) and focus groups (with healthcare professionals); 2) Synthesis of the literature. RESULTS: The semi-directed interviews (n = 11), the two focus groups (n = 11) and the literature synthesis (n = 50 articles) identified information needs such as learning about ongoing research projects, scientific advances and research results, the potential benefits and risks associated with different types of research projects, and identified values surrounding research participation: helping other generations, trust, obtaining better clinical follow-up, and socialization. CONCLUSION: This paper provides useful recommendations to support researchers and clinicians in developing material to inform individuals with neuromuscular diseases about research participation

    The Role of Parvalbumin-positive Interneurons in Auditory Steady-State Response Deficits in Schizophrenia

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    © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.Despite an increasing body of evidence demonstrating subcellular alterations in parvalbumin-positive (PV+) interneurons in schizophrenia, their functional consequences remain elusive. Since PV+ interneurons are involved in the generation of fast cortical rhythms, these changes have been hypothesized to contribute to well-established alterations of beta and gamma range oscillations in patients suffering from schizophrenia. However, the precise role of these alterations and the role of different subtypes of PV+ interneurons is still unclear. Here we used a computational model of auditory steady-state response (ASSR) deficits in schizophrenia. We investigated the differential effects of decelerated synaptic dynamics, caused by subcellular alterations at two subtypes of PV+ interneurons: basket cells and chandelier cells. Our simulations suggest that subcellular alterations at basket cell synapses rather than chandelier cell synapses are the main contributor to these deficits. Particularly, basket cells might serve as target for innovative therapeutic interventions aiming at reversing the oscillatory deficits.Peer reviewe

    New nurses burnout and workplace wellbeing:The influence of authentic leadership and psychological capital

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    The detrimental effects of burnout on nurses’ health and wellbeing are well documented and positive leadership has been shown to be an important organizational resource for discouraging the development of burnout. Intrapersonal resources also play a protective role against workplace stressors. This study investigated the influence of authentic leadership, an organizational resource, and psychological capital, an intrapersonal resource, on new graduate burnout, occupational satisfaction, and workplace mental health over the first year of employment (n = 205). Results supported the protective role of organizational and intrapersonal resources against burnout, job dissatisfaction, and mental health. © 2014 The Authors. Published by Elsevier GmbH. This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/)
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