61 research outputs found
Avaliação, por graduandos de enfermagem, de ambiente virtual de aprendizagem para ensino de fisiologia endócrina
Gut microbiome composition is linked to whole grain-induced immunological improvements
The involvement of the gut microbiota in metabolic disorders, and the ability of whole grains to affect both host metabolism and gut microbial ecology, suggest that some benefits of whole grains are mediated through their effects on the gut microbiome. Nutritional studies that assess the effect of whole grains on both the gut microbiome and human physiology are needed. We conducted a randomized cross-over trial with four-week treatments in which 28 healthy humans consumed a daily dose of 60âg of whole-grain barley (WGB), brown rice (BR), or an equal mixture of the two (BR+WGB), and characterized their impact on fecal microbial ecology and blood markers of inflammation, glucose and lipid metabolism. All treatments increased microbial diversity, the Firmicutes/Bacteroidetes ratio, and the abundance of the genus Blautia in fecal samples. The inclusion of WGB enriched the genera Roseburia, Bifidobacterium and Dialister, and the species Eubacterium rectale, Roseburia faecis and Roseburia intestinalis. Whole grains, and especially the BR+WGB treatment, reduced plasma interleukin-6 (IL-6) and peak postprandial glucose. Shifts in the abundance of Eubacterium rectale were associated with changes in the glucose and insulin postprandial response. Interestingly, subjects with greater improvements in IL-6 levels harbored significantly higher proportions of Dialister and lower abundance of Coriobacteriaceae. In conclusion, this study revealed that a short-term intake of whole grains induced compositional alterations of the gut microbiota that coincided with improvements in host physiological measures related to metabolic dysfunctions in humans
Observation of Two New Excited Îb0 States Decaying to Îb0 K-Ï+
Two narrow resonant states are observed in the Îb0K-Ï+ mass spectrum using a data sample of proton-proton collisions at a center-of-mass energy of 13 TeV, collected by the LHCb experiment and corresponding to an integrated luminosity of 6 fb-1. The minimal quark content of the Îb0K-Ï+ system indicates that these are excited Îb0 baryons. The masses of the Îb(6327)0 and Îb(6333)0 states are m[Îb(6327)0]=6327.28-0.21+0.23±0.12±0.24 and m[Îb(6333)0]=6332.69-0.18+0.17±0.03±0.22 MeV, respectively, with a mass splitting of Îm=5.41-0.27+0.26±0.12 MeV, where the uncertainties are statistical, systematic, and due to the Îb0 mass measurement. The measured natural widths of these states are consistent with zero, with upper limits of Î[Îb(6327)0]<2.20(2.56) and Î[Îb(6333)0]<1.60(1.92) MeV at a 90% (95%) credibility level. The significance of the two-peak hypothesis is larger than nine (five) Gaussian standard deviations compared to the no-peak (one-peak) hypothesis. The masses, widths, and resonant structure of the new states are in good agreement with the expectations for a doublet of 1D Îb0 resonances
Measurement of the CKM angle using with decays
A model-dependent amplitude analysis of the decay is performed using proton-proton collision data
corresponding to an integrated luminosity of 3.0fb, recorded at
and by the LHCb experiment. The CP violation observables
and , sensitive to the CKM angle , are measured to
be \begin{eqnarray*} x_- &=& -0.15 \pm 0.14 \pm 0.03 \pm 0.01, y_- &=& 0.25 \pm
0.15 \pm 0.06 \pm 0.01, x_+ &=& 0.05 \pm 0.24 \pm 0.04 \pm 0.01, y_+ &=&
-0.65^{+0.24}_{-0.23} \pm 0.08 \pm 0.01, \end{eqnarray*} where the first
uncertainties are statistical, the second systematic and the third arise from
the uncertainty on the amplitude model. These
are the most precise measurements of these observables. They correspond to
and , where is
the magnitude of the ratio of the suppressed and favoured decay amplitudes, in a mass region of around the
mass and for an absolute value of the cosine of the decay
angle larger than .Comment: All figures and tables, along with any supplementary material and
additional information, are available at
https://lhcbproject.web.cern.ch/lhcbproject/Publications/LHCbProjectPublic/LHCb-PAPER-2016-007.htm
Search for dark photons produced in 13 TeV collisions
Searches are performed for both promptlike and long-lived dark photons,
A
0
, produced in proton-proton
collisions at a center-of-mass energy of 13 TeV, using
A
0
â
Ό
ĂŸ
Ό
â
decays and a data sample corresponding
to an integrated luminosity of
1
.
6
fb
â
1
collected with the LHCb detector. The promptlike
A
0
search covers
the mass range from near the dimuon threshold up to 70 GeV, while the long-lived
A
0
search is restricted to
the low-mass region
214
<m
Ă°
A
0
Ă
<
350
MeV. No evidence for a signal is found, and 90% confidence
level exclusion limits are placed on the
Îł
â
A
0
kinetic-mixing strength. The constraints placed on promptlike
dark photons are the most stringent to date for the mass range
10
.
6
<m
Ă°
A
0
Ă
<
70
GeV, and are
comparable to the best existing limits for
m
Ă°
A
0
Ă
<
0
.
5
GeV. The search for long-lived dark photons is the
first to achieve sensitivity using a displaced-vertex signature
Direct CP violation in charmless three-body decays of B± mesons
Measurements of
C
P
asymmetries in charmless three-body decays of
B
±
mesons are reported using proton-proton collision data collected by the LHCb detector, corresponding to an integrated luminosity of
5.9
â
â
fb
â
1
. The previously observed
C
P
asymmetry in
B
±
â
Ï
±
K
+
K
â
decays is confirmed, and
C
P
asymmetries are observed with a significance of more than five standard deviations in the
B
±
â
Ï
±
Ï
+
Ï
â
and
B
±
â
K
±
K
+
K
â
decays, while the
C
P
asymmetry of
B
±
â
K
±
Ï
+
Ï
â
decays is confirmed to be compatible with zero. The distributions of these asymmetries are also studied as a function of the three-body phase space and suggest contributions from rescattering and resonance interference processes. An indication of the presence of the decays
B
±
â
Ï
±
Ï
c
0
(
1
P
)
in both
B
±
â
Ï
±
Ï
+
Ï
â
and
B
±
â
Ï
±
K
+
K
â
decays is observed, as is
C
P
violation involving these amplitudes
Measurement of antiproton production from antihyperon decays in p He collisions at âsNN = 110 GeV
The interpretation of cosmic antiproton flux measurements from space-borne experiments is currently limited by the knowledge of the antiproton production cross-section in collisions between primary cosmic rays and the interstellar medium. Using collisions of protons with an energy of 6.5TeV incident on helium nuclei at rest in the proximity of the interaction region of the LHCb experiment, the ratio of antiprotons originating from antihyperon decays to prompt production is measured for antiproton momenta between 12 and 110GeV. The dominant antihyperon contribution, namely ÎÂŻâpÂŻÏ+ decays from promptly produced ÎÂŻ particles, is also exclusively measured. The results complement the measurement of prompt antiproton production obtained from the same data sample. At the energy scale of this measurement, the antihyperon contributions to antiproton production are observed to be significantly larger than predictions of commonly used hadronic production models
Measurement of J/Ï -pair production in pp collisions at âs = 13 TeV and study of gluon transverse-momentum dependent PDFs
The production cross-section of J/Ï pairs in proton-proton collisions at a centre-of-mass energy of âs = 13 TeV is measured using a data sample corresponding to an integrated luminosity of 4.2 fbâ1 collected by the LHCb experiment. The measurement is performed with both J/Ï mesons in the transverse momentum range 0 < pT< 14 GeV/c and rapidity range 2.0 < y < 4.5. The cross-section of this process is measured to be 16.36 ± 0.28 (stat) ± 0.88 (syst) nb. The contributions from single-parton scattering and double-parton scattering are separated based on the dependence of the cross-section on the absolute rapidity difference ây between the two J/Ï mesons. The effective cross-section of double-parton scattering is measured to be Ïeff = 13.1 ± 1.8 (stat) ± 2.3 (syst) mb. The distribution of the azimuthal angle ÏCS of one of the J/Ï mesons in the Collins-Soper frame and the pT-spectrum of the J/Ï pairs are also measured for the study of the gluon transverse-momentum dependent distributions inside protons. The extracted values of âšcos 2ÏCSâ© and âšcos 4ÏCSâ© are consistent with zero, but the presence of azimuthal asymmetry at a few percent level is allowed
Social hue : a subtle awareness system for connecting the elderly and their caregivers
In this position paper, we propose an unobtrusive solution for improving bonding relations between the elderly and their caregivers, through the Social Hue. The Social Hue is a bidirectional application that is based on the Philips Hue light. To create social presence, activity and emotional states will be detected through sensors and will be transformed into ambient lighting into the elder's home and vice versa without overt communication from participants. Findings are expected to provide a deeper insight on the notion of subtle awareness in relation to social connectivity between the elderly and their caregivers
Pervasive sensing for social connectedness
Global population ageing is an emerging challenge of the twenty-first century. In an era of pervasive computing (i.e. the proliferation of ever-present smart devices), governments, companies, and academic institutions are working together to develop and promote cutting-edge initiatives that sustain the quality of life and address the complexities and opportunities of an ageing world. In this chapter, we propose a user-centred approach within a multidisciplinary framework, which incorporates human-computer interaction, social science, signal processing, and pervasive computing, to inspire the design of a bidirectional context-aware system to support social connectedness between the elderly and their caregivers. Following a review of previous works on socio-technical awareness systems and human activity recognition models, we describe our user-driven methodological approach and demonstrate the value and potential benefits of bidirectional activity-based peripheral systems within ambient assisted living environment
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