A re-appraisal of the reliability of the 20 m multi-stage shuttle run test

This is the author's PDF version of an article published in European journal of applied physiology in 2007. The original publication is available at www.springerlink.co

Colour Gradients and the Colour-Magnitude Relation: Different Properties of Brightest Cluster Galaxies and E/S0 Galaxies in the Sloan Digital Sky Survey

We examine the colour-magnitude relation of approximately 5000 Brightest Cluster Galaxies (BCGs) in the Sloan Digital Sky Survey, and compare with non-BCG E/S0 galaxies. The colour-magnitude and colour-sigma (velocity dispersion) relations are flatter in slope (by a factor of about 2) for BCGs than for non-BCG E/S0s, and the BCGs also tend to be redder by 0.01 magnitudes in g-r. We investigate radial colour gradients in both samples, using the ratio of the de Vaucouleurs radii in the g and r bands. We find BCGs have significantly flatter (by 23%) mean colour gradients than other high luminosity E/S0s. In early-type galaxies, the colour gradients are strongest at intermediate luminosities of Mr=-22. Colour gradients in E/S0s increase with radius (up to 10kpc) and are negatively correlated with 10sigma + Mr (velocity dispersion relative to luminosity) and with mass density. The gradients also tend to decrease with increasing stellar age. These trends are weak or not seen in BCGs, in which the mean colour gradient is low whatever the other properties. We discuss possible explanations, which involve a greater amount of dry merging in the formation history of the BCGs.Comment: 16 pages, 24 figures, revised, accepted for publication in MNRAS

M/L and Color Evolution for A Deep Sample of M* Cluster Galaxies at z~1: The Formation Epoch and the Tilt of the Fundamental Plane

We have measured velocity dispersions for a sample of 36 galaxies with J < 21.2 or Mr < -20.6 mag in MS1054-03, a massive cluster of galaxies at z = 0.83. Our data are of uniformly high quality down to our selection limit, our 16-hour exposures typically yielding errors of only \delta(dispersion)~10% for L* and fainter galaxies. By combining our measurements with data from the literature, we have 53 cluster galaxies with measured dispersions, and HST/ACS-derived sizes, colors and surface brightnesses. This sample is complete for the typical L* galaxy at z~1, unlike most previous z~1 cluster samples which are complete only for the massive cluster members (>1e11 M_sun). We find no evidence for a change in the tilt of the fundamental plane (FP). Nor do we find evidence for evolution in the slope of the color-dispersion relation and M/L_B-dispersion relations; measuring evolution at a fixed dispersion should minimize the impact of size evolution found in other work. The M/L_B at fixed dispersion evolves by \Delta log10 M/L_B=-0.50 +/- 0.03 between z=0.83 and z=0.02 or d(log10 M/L_B)=-0.60 +/- 0.04 dz, and we find \Delta (U-V)_z=-0.24 +/- 0.02 mag at fixed dispersion in the rest-frame, matching the expected evolution in M/L_B within 2.25 standard deviations. The implied formation redshift from both the color and M/L_B evolution is z*=2.0 +/- 0.2 +/- 0.3 (sys), during the epoch in which the cosmic star-formation activity peaked, with the systematic uncertainty showing the dependence of z* on the assumptions we make about the stellar populations. The lack of evolution in either the tilt of the FP or in the M/L- and color-dispersion relations imply that the formation epoch depends weakly on mass, ranging from z*=2.3 +1.3 -0.3 at 300 km/s to z*=1.7 +0.3 -0.2 at 160 km/s and implies that the IMF similarly varies slowly with galaxy mass.Comment: revised; typos corrected, references updated, and other cosmetic changes to meet ApJ format ApJ accepted, 22 pages in emulate ApJ format, 8 color figures, 1 b/w figur

Thalamic inputs to dorsomedial striatum are involved in inhibitory control: evidence from the five-choice serial reaction time task in rats

Rationale Corticostriatal circuits are widely implicated in the top-down control of attention including inhibitory control and behavioural flexibility. However, recent neurophysiological evidence also suggests a role for thalamic inputs to striatum in behaviours related to salient, reward-paired cues. Objectives Here, we used designer receptors exclusively activated by designer drugs (DREADDs) to investigate the role of parafascicular (Pf) thalamic inputs to the dorsomedial striatum (DMS) using the five-choice serial reaction time task (5CSRTT) in rats. Methods The 5CSRTT requires sustained attention in order to detect spatially and temporally distributed visual cues and provides measures of inhibitory control related to impulsivity (premature responses) and compulsivity (perseverative responses). Rats underwent bilateral Pf injections of the DREADD vector, AAV2-CaMKIIa-HA-hM4D(Gi)-IRES-mCitrine. The DREADD agonist, clozapine N-oxide (CNO; 1 μl bilateral; 3 μM) or vehicle, was injected into DMS 1 h before behavioural testing. Task parameters were manipulated to increase attention load or reduce stimulus predictability respectively. Results We found that inhibition of the Pf-DMS projection significantly increased perseverative responses when stimulus predictability was reduced but had no effect on premature responses or response accuracy, even under increased attentional load. Control experiments showed no effects on locomotor activity in an open field. Conclusions These results complement previous lesion work in which the DMS and orbitofrontal cortex were similarly implicated in perseverative responses and suggest a specific role for thalamostriatal inputs in inhibitory control

Possible thermochemical disequilibrium in the atmosphere of the exoplanet GJ 436b

The nearby extrasolar planet GJ 436b--which has been labelled as a 'hot Neptune'--reveals itself by the dimming of light as it crosses in front of and behind its parent star as seen from Earth. Respectively known as the primary transit and secondary eclipse, the former constrains the planet's radius and mass, and the latter constrains the planet's temperature and, with measurements at multiple wavelengths, its atmospheric composition. Previous work using transmission spectroscopy failed to detect the 1.4-\mu m water vapour band, leaving the planet's atmospheric composition poorly constrained. Here we report the detection of planetary thermal emission from the dayside of GJ 436b at multiple infrared wavelengths during the secondary eclipse. The best-fit compositional models contain a high CO abundance and a substantial methane (CH4) deficiency relative to thermochemical equilibrium models for the predicted hydrogen-dominated atmosphere. Moreover, we report the presence of some H2O and traces of CO2. Because CH4 is expected to be the dominant carbon-bearing species, disequilibrium processes such as vertical mixing and polymerization of methane into substances such as ethylene may be required to explain the hot Neptune's small CH4-to-CO ratio, which is at least 10^5 times smaller than predicted

Hybridization in parasites: consequences for adaptive evolution, pathogenesis and public health in a changing world

[No abstract available

Two Earth-sized planets orbiting Kepler-20

Since the discovery of the first extrasolar giant planets around Sun-like stars, evolving observational capabilities have brought us closer to the detection of true Earth analogues. The size of an exoplanet can be determined when it periodically passes in front of (transits) its parent star, causing a decrease in starlight proportional to its radius. The smallest exoplanet hitherto discovered has a radius 1.42 times that of the Earth's radius (R Earth), and hence has 2.9 times its volume. Here we report the discovery of two planets, one Earth-sized (1.03R Earth) and the other smaller than the Earth (0.87R Earth), orbiting the star Kepler-20, which is already known to host three other, larger, transiting planets. The gravitational pull of the new planets on the parent star is too small to measure with current instrumentation. We apply a statistical method to show that the likelihood of the planetary interpretation of the transit signals is more than three orders of magnitude larger than that of the alternative hypothesis that the signals result from an eclipsing binary star. Theoretical considerations imply that these planets are rocky, with a composition of iron and silicate. The outer planet could have developed a thick water vapour atmosphere.Comment: Letter to Nature; Received 8 November; accepted 13 December 2011; Published online 20 December 201

The history of star formation and mass assembly in early-type galaxies

We define a volume limited sample of over 14,000 early-type galaxies (ETGs) selected from data release six of the Sloan Digital Sky Survey. The density of environment of each galaxy is robustly measured. By comparing narrow band spectral line indices with recent models of simple stellar populations (SSPs) we investigate trends in the star formation history as a function of galaxy mass (velocity dispersion), density of environment and galactic radius. We find that age, metallicity and alpha-enhancement all increase with galaxy mass and that field ETGs are younger than their cluster counterparts by ~2 Gyr. We find negative radial metallicity gradients for all masses and environments, and positive radial age gradients for ETGs with velocity dispersion over 180 km/s. Our results are qualitatively consistent with a relatively simple picture for ETG evolution in which the low-mass halos accreted by a proto-ETG contained not only gas but also a stellar population. This fossil population is preferentially found at large radii in massive ETGs because the stellar accretions were dissipationless. We estimate that the typical, massive ETG should have been assembled at z < 3.5. The process is similar in the cluster and the field but occurred earlier in dense environments.Comment: 5 pages, 2 figures. Submitted to MNRA

Evaluating the successful implementation of evidence into practice using the PARiHS framework : theoretical and practical challenges

Background The PARiHS framework (Promoting Action on Research Implementation in Health Services) has proved to be a useful practical and conceptual heuristic for many researchers and practitioners in framing their research or knowledge translation endeavours. However, as a conceptual framework it still remains untested and therefore its contribution to the overall development and testing of theory in the field of implementation science is largely unquantified. Discussion This being the case, the paper provides an integrated summary of our conceptual and theoretical thinking so far and introduces a typology (derived from social policy analysis) used to distinguish between the terms conceptual framework, theory and model – important definitional and conceptual issues in trying to refine theoretical and methodological approaches to knowledge translation. Secondly, the paper describes the next phase of our work, in particular concentrating on the conceptual thinking and mapping that has led to the generation of the hypothesis that the PARiHS framework is best utilised as a two-stage process: as a preliminary (diagnostic and evaluative) measure of the elements and sub-elements of evidence (E) and context (C), and then using the aggregated data from these measures to determine the most appropriate facilitation method. The exact nature of the intervention is thus determined by the specific actors in the specific context at a specific time and place. In the process of refining this next phase of our work, we have had to consider the wider issues around the use of theories to inform and shape our research activity; the ongoing challenges of developing robust and sensitive measures; facilitation as an intervention for getting research into practice; and finally to note how the current debates around evidence into practice are adopting wider notions that fit innovations more generally. Summary The paper concludes by suggesting that the future direction of the work on the PARiHS framework is to develop a two-stage diagnostic and evaluative approach, where the intervention is shaped and moulded by the information gathered about the specific situation and from participating stakeholders. In order to expedite the generation of new evidence and testing of emerging theories, we suggest the formation of an international research implementation science collaborative that can systematically collect and analyse experiences of using and testing the PARiHS framework and similar conceptual and theoretical approaches. We also recommend further refinement of the definitions around conceptual framework, theory, and model, suggesting a wider discussion that embraces multiple epistemological and ontological perspectives

Transverse Fresnel-Fizeau drag effects in strongly dispersive media

A light beam normally incident upon an uniformly moving dielectric medium is in general subject to bendings due to a transverse Fresnel-Fizeau light drag effect. In conventional dielectrics, the magnitude of this bending effect is very small and hard to detect. Yet, it can be dramatically enhanced in strongly dispersive media where slow group velocities in the m/s range have been recently observed taking advantage of the electromagnetically induced transparency (EIT) effect. In addition to the usual downstream drag that takes place for positive group velocities, we predict a significant anomalous upstream drag to occur for small and negative group velocities. Furthermore, for sufficiently fast speeds of the medium, higher order dispersion terms are found to play an important role and to be responsible for peculiar effects such as light propagation along curved paths and the restoration of the spatial coherence of an incident noisy beam. The physics underlying this new class of slow-light effects is thoroughly discussed