Curvature sensor for the measurement of the static corneal topography and the dynamic tear film topography in the human eye

A system to measure the topography of the first optical surface of the human eye noninvasively by using a curvature sensor is described. The static corneal topography and the dynamic topography of the tear film can both be measured, and the topographies obtained are presented. The system makes possible the study of the dynamic aberrations introduced by the tear film to determine their contribution to the overall ocular aberrations in healthy eyes, eyes with corneal pathologies, and eyes wearing contact lenses

Effect of many modes on self-polarization and photochemical suppression in cavities

The standard description of cavity-modified molecular reactions typically involves a single (resonant) mode, while in reality, the quantum cavity supports a range of photon modes. Here, we demonstrate that as more photon modes are accounted for, physicochemical phenomena can dramatically change, as illustrated by the cavity-induced suppression of the important and ubiquitous process of proton-coupled electron-transfer. Using a multi-trajectory Ehrenfest treatment for the photon-modes, we find that self-polarization effects become essential, and we introduce the concept of self-polarization-modified Born–Oppenheimer surfaces as a new construct to analyze dynamics. As the number of cavity photon modes increases, the increasing deviation of these surfaces from the cavity-free Born–Oppenheimer surfaces, together with the interplay between photon emission and absorption inside the widening bands of these surfaces, leads to enhanced suppression. The present findings are general and will have implications for the description and control of cavity-driven physical processes of molecules, nanostructures, and solids embedded in cavities

3D SIMULATION OF A 500KG UO2 MELT IN A COLD CRUCIBLE INDUCTION FURNACE

International audienc

The role of the Roper resonance in n p --> d (pi pi)

In this work, a model for the n p --> d (pi pi) reaction is developed. It is shown that the structure of the deuteron momentum spectra for a neutron beam momentum of 1.46 GeV can be explained as a consequence of the interplay of two mechanisms involving the excitation of the N^*(1440) resonance and its subsequent decay into N (pi pi)^{T=0}_{S-wave} and Delta pi respectively. The relevance of the present analysis for the study of the Roper excitation and decay properties, as well as for the interpretation of other two-pion production experiments is discussed.Comment: 13 pages, 6 ps figure

Application of Current Algebra in Three Pseudoscalar Meson Decays of τ\tau Lepton

The decays of $\tau \to 3\pi \nu$ and $\tau \to \pi K^{*} \nu, K\rho \nu$ are calculated using the hard pion and kaon current algebra and assuming the Axial-Vector meson dominance of the hadronic axial currents. Using the experimental data on their masses and widths, the $\tau$ decay branching ratios into these channels are calculated and found to be in a reasonable agreement with the experimental data. In particular, using the available Aleph data on the $3\pi$ spectrum, we determine the $A_1$ parameters, $m_A=1.24\pm 0.02 GeV$, $\Gamma _A=0.43\pm 0.02$ GeV; the hard current algebra calculation yields a $3\pi$ branching ratio of $19 \pm 3 \%$.Comment: 14 pages, Tex, 6 included figure

Fermi gamma-ray `bubbles' from stochastic acceleration of electrons

Gamma-ray data from Fermi-LAT reveal a bi-lobular structure extending up to 50 degrees above and below the galactic centre, which presumably originated in some form of energy release there less than a few million years ago. It has been argued that the gamma-rays arise from hadronic interactions of high energy cosmic rays which are advected out by a strong wind, or from inverse-Compton scattering of relativistic electrons accelerated at plasma shocks present in the bubbles. We explore the alternative possibility that the relativistic electrons are undergoing stochastic 2nd-order Fermi acceleration by plasma wave turbulence through the entire volume of the bubbles. The observed gamma-ray spectral shape is then explained naturally by the resulting hard electron spectrum and inverse Compton losses. Rather than a constant volume emissivity as in other models, we predict a nearly constant surface brightness, and reproduce the observed sharp edges of the bubbles.Comment: 4 pages, 4 figures; REVTeX4-1; discussion amended and one figure added; to appear in PR

Impact of the European Clinical Trials Directive on prospective academic clinical trials associated with BMT

The European Clinical Trials Directive (EU 2001; 2001/20/EC) was introduced to improve the efficiency of commercial and academic clinical trials. Concerns have been raised by interested organizations and institutions regarding the potential for negative impact of the Directive on non-commercial European clinical research. Interested researchers within the European Group for Blood and Marrow Transplantation (EBMT) were surveyed to determine whether researcher experiences confirmed this view. Following a pilot study, an internet-based questionnaire was distributed to individuals in key research positions in the European haemopoietic SCT community. Seventy-one usable questionnaires were returned from participants in different EU member states. The results indicate that the perceived impact of the European Clinical Trials Directive has been negative, at least in the research areas of interest to the EBMT

Probing Short Range Nucleon Correlations in High Energy Hard Quasielastic pd Reactions

We show that the strong dependence of the amplitude for $NN$ hard scattering on the collision energy can be used to magnify the effects of short range nucleon correlations in quasielastic $pd$ scattering. Under specific kinematical conditions the effect of initial and final state interactions can be accounted for by rescaling the cross section calculated within the plane wave impulse approximation. The feasibility to investigate the role of relativistic effects in the deuteron wave function is demonstrated by comparing the predictions of different formalisms. Binding effects due to short range correlations in deuteron are discussed as well.Comment: 18 pages (LaTex) + 10 postscript figs (available on request

Magnetic field turbulence in the solar wind at sub-ion scales: in situ observations and numerical simulations

We investigate the transition of the solar wind turbulent cascade from MHD to sub-ion range by means of a detail comparison between in situ observations and hybrid numerical simulations. In particular we focus on the properties of the magnetic field and its component anisotropy in Cluster measurements and hybrid 2D simulations. First, we address the angular distribution of wave-vectors in the kinetic range between ion and electron scales by studying the variance anisotropy of the magnetic field components. When taking into account the single-direction sampling performed by spacecraft in the solar wind, the main properties of the fluctuations observed in situ are also recovered in our numerical description. This result confirms that solar wind turbulence in the sub-ion range is characterized by a quasi-2D gyrotropic distribution of k-vectors around the mean field. We then consider the magnetic compressibility associated with the turbulent cascade and its evolution from large-MHD to sub-ion scales. The ratio of field-aligned to perpendicular fluctuations, typically low in the MHD inertial range, increases significantly when crossing ion scales and its value in the sub-ion range is a function of the total plasma beta only, as expected from theoretical predictions, with higher magnetic compressibility for higher beta. Moreover, we observe that this increase has a gradual trend from low to high beta values in the in situ data; this behaviour is well captured by the numerical simulations. The level of magnetic field compressibility that is observed in situ and in the simulations is in fairly good agreement with theoretical predictions, especially at high beta, suggesting that in the kinetic range explored the turbulence is supported by low-frequency and highly-oblique fluctuations in pressure balance, like kinetic Alfv\'en waves or other slowly evolving coherent structures.Comment: Manuscript submitted to Frontiers Astronomy and Space Sciences, Research Topic: Improving the Understanding of Kinetic Processes in Solar Wind and Magnetosphere: From CLUSTER to MM

A method for detection of structure

Context. In order to understand the evolution of molecular clouds it is important to identify the departures from self-similarity associated with the scales of self-gravity and the driving of turbulence. Aims. A method is described based on structure functions for determining whether a region of gas, such as a molecular cloud, is fractal or contains structure with characteristic scale sizes. Methods. Using artificial data containing structure it is shown that derivatives of higher order structure functions provide a powerful way to detect the presence of characteristic scales should any be present and to estimate the size of such structures. The method is applied to observations of hot H2 in the Kleinman-Low nebula, north of the Trapezium stars in the Orion Molecular Cloud, including both brightness and velocity data. The method is compared with other techniques such as Fourier transform and histogram techniques. Results. It is found that the density structure, represented by H2 emission brightness in the K-band (2-2.5micron), exhibits mean characteristic sizes of 110, 550, 1700 and 2700AU. The velocity data show the presence of structure at 140, 1500 and 3500AU. Compared with other techniques such as Fourier transform or histogram, the method appears both more sensitive to characteristic scales and easier to interpret.Comment: Astronomy and Astrophysics, in pres