Noncooperative and Cooperative Transmission Schemes with Precoding and Beamforming

The next generation mobile networks are expected to provide multimedia applications with a high quality of service. On the other hand, interference among multiple base stations (BS) that co-exist in the same location limits the capacity of wireless networks. In conventional wireless networks, the base stations do not cooperate with each other. The BSs transmit individually to their respective mobile stations (MS) and treat the transmission from other BSs as interference. An alternative to this structure is a network cooperation structure. Here, BSs cooperate with other BSs to simultaneously transmit to their respective MSs using the same frequency band at a given time slot. By doing this, we significantly increase the capacity of the networks. This thesis presents novel research results on a noncooperative transmission scheme and a cooperative transmission scheme for multi-user multiple-input-multiple-output orthogonal frequency division multiplexing (MIMO-OFDM). We first consider the performance limit of a noncooperative transmission scheme. Here, we propose a method to reduce the interference and increase the throughput of orthogonal frequency division multiplexing (OFDM) systems in co-working wireless local area networks (WLANs) by using joint adaptive multiple antennas(AMA) and adaptive modulation (AM) with acknowledgement (ACK) Eigen-steering. The calculation of AMA and AM are performed at the receiver. The AMA is used to suppress interference and to maximize the signal-to-interference-plus-noise ratio (SINR). The AM scheme is used to allocate OFDM sub-carriers, power, and modulation mode subject to the constraints of power, discrete modulation, and the bit error rate (BER). The transmit weights, the allocation of power, and the allocation of sub-carriers are obtained at the transmitter using ACK Eigen-steering. The derivations of AMA, AM, and ACK Eigen-steering are shown. The performance of joint AMA and AM for various AMA configurations is evaluated through the simulations of BER and spectral efficiency (SE) against SIR. To improve the performance of the system further, we propose a practical cooperative transmission scheme to mitigate against the interference in co-working WLANs. Here, we consider a network coordination among BSs. We employ Tomlinson Harashima precoding (THP), joint transmit-receive beamforming based on SINR (signal-to-interference-plus-noise-ratio) maximization, and an adaptive precoding order to eliminate co-working interference and achieve bit error rate (BER) fairness among different users. We also consider the design of the system when partial channel state information (CSI) (where each user only knows its own CSI) and full CSI (where each user knows CSI of all users) are available at the receiver respectively. We prove analytically and by simulation that the performance of our proposed scheme will not be degraded under partial CSI. The simulation results show that the proposed scheme considerably outperforms both the existing noncooperative and cooperative transmission schemes. A method to design a spectrally efficient cooperative downlink transmission scheme employing precoding and beamforming is also proposed. The algorithm eliminates the interference and achieves symbol error rate (SER) fairness among different users. To eliminate the interference, Tomlinson Harashima precoding (THP) is used to cancel part of the interference while the transmit-receive antenna weights cancel the remaining one. A new novel iterative method is applied to generate the transmit-receive antenna weights. To achieve SER fairness among different users and further improve the performance of MIMO systems, we develop algorithms that provide equal SINR across all users and order the users so that the minimum SINR for each user is maximized. The simulation results show that the proposed scheme considerably outperforms existing cooperative transmission schemes in terms of the SER performance and complexity and approaches an interference free performance under the same configuration. We could improve the performance of the proposed interference cancellation further. This is because the proposed interference cancellation does not consider receiver noise when calculating the transmit-receive weight antennas. In addition, the proposed scheme mentioned above is designed specifically for a single-stream multi-user transmission. Here, we employ THP precoding and an iterative method based on the uplink-downlink duality principle to generate the transmit-receive antenna weights. The algorithm provides an equal SINR across all users. A simpler method is then proposed by trading off the complexity with a slight performance degradation. The proposed methods are extended to also work when the receiver does not have complete Channel State Informations (CSIs). A new method of setting the user precoding order, which has a much lower complexity than the VBLAST type ordering scheme but with almost the same performance, is also proposed. The simulation results show that the proposed schemes considerably outperform existing cooperative transmission schemes in terms of SER performance and approach an interference free performance. In all the cooperative transmission schemes proposed above, we use THP to cancel part of the interference. In this thesis, we also consider an alternative approach that bypasses the use of THP. The task of cancelling the interference from other users now lies solely within the transmit-receive antenna weights. We consider multiuser Gaussian broadcast channels with multiple antennas at both transmitter and receivers. An iterative multiple beamforming (IMB) algorithm is proposed, which is flexible in the antenna configuration and performs well in low to moderate data rates. Its capacity and bit error rate performance are compared with the ones achieved by the traditional zero-forcing method

The personality characteristics of emergency nurses

Background: There are ever increasing demands on the emergency nursing workforce so it is necessary to consider how to enhance the recruitment and retention of emergency nurses. Personality is known to influence occupational choice, yet there is a lack of research exploring how personality may influence the workforce decisions of emergency nurses. Aims: To establish the personality profile of a sample of emergency nurses, and to explore whether any relationship exists between their personality characteristics and time spent working within emergency nursing. Methods: A standardised personality assessment instrument, the NEO™-PI-3, was used along with a demographic survey. Data were collected from 72 emergency nurses in an Australian Emergency Department between July and October 2012. Descriptive statistics were used to report demographics and the personality assessment results were compared against general population norms in each of the five personality domains and their 30 associated facets using a one-sample t-test. A two-sided alpha level of .01 was determined to indicate statistical significance. Results: Emergency nurse participants scored higher than the population norms in the domains of extraversion, openness to experience and agreeableness, and in twelve facets, including excitement seeking, vulnerability and competence. Conclusion: The personality profile of this sample of emergency nurses is different from the established population norms. Further research is required to establish whether these study results are applicable to the wider emergency nurse workforce and to establish any link with personality and other nursing specialty choice, which may assist in improving nursing workforce retention and recruitment

Interpretation and Visualization of Non-Linear Data Fusion in Kernel Space: Study on Metabolomic Characterization of Progression of Multiple Sclerosis

Contains fulltext : 93904.pdf (publisher's version ) (Open Access

Fusion of metabolomics and proteomics data for biomarkers discovery: case study on the experimental autoimmune encephalomyelitis

Contains fulltext : 91843.pdf (publisher's version ) (Open Access)12 p

Posttraumatic stress disorder among female street-based sex workers in the greater Sydney area, Australia

BACKGROUND: This paper examines rates of exposure to work-related violence and other trauma, and the prevalence of lifetime and current posttraumatic stress disorder (PTSD) among female street-based sex workers. It also investigates associations between current PTSD symptoms and: demographic characteristics, psychiatric comorbidity, injecting and sex risk behaviours, and trauma history. METHODS: Cross sectional data collected from 72 women via face to face structured interviews. The interview included structured diagnostic assessment of DSM-IV PTSD; drug dependence; depression; experience of childhood trauma; and an assessment of sex working history. RESULTS: All but one of the women interviewed reported experiencing trauma, with the majority reporting multiple traumas that typically began in early childhood. Child sexual abuse, adult sexual assault and work related violence were commonly reported. Just under half of the women met DSM-IV criteria for PTSD and approximately one-third reported current PTSD symptoms. Adult sexual assault was associated with current PTSD symptoms. Depression and drug dependence were also highly prevalent; cocaine dependence in particular was associated with elevated rates of injecting risk and sexual risk behaviours. CONCLUSION: These women reported complex trauma histories and despite ongoing opportunities for clinical intervention, they continued to experience problems, suggesting that current models of treatment may not be appropriate. More targeted interventions, and integrated mental health and drug treatment services are needed to address the problems these women are experiencing. Outreach services to these women remain a priority. Education strategies to reduce risky injecting and sexual behaviours among sex workers should also remain a priority

Multiproject–multicenter evaluation of automatic brain tumor classification by magnetic resonance spectroscopy

Contains fulltext : 75361.pdf (publisher's version ) (Open Access)14 p

A short history of the 5-HT2C receptor: from the choroid plexus to depression, obesity and addiction treatment

This paper is a personal account on the discovery and characterization of the 5-HT2C receptor (first known as the 5- HT1C receptor) over 30 years ago and how it translated into a number of unsuspected features for a G protein-coupled receptor (GPCR) and a diversity of clinical applications. The 5-HT2C receptor is one of the most intriguing members of the GPCR superfamily. Initially referred to as 5-HT1CR, the 5-HT2CR was discovered while studying the pharmacological features and the distribution of [3H]mesulergine-labelled sites, primarily in the brain using radioligand binding and slice autoradiography. Mesulergine (SDZ CU-085), was, at the time, best defined as a ligand with serotonergic and dopaminergic properties. Autoradiographic studies showed remarkably strong [3H]mesulergine-labelling to the rat choroid plexus. [3H]mesulergine-labelled sites had pharmacological properties different from, at the time, known or purported 5-HT receptors. In spite of similarities with 5-HT2 binding, the new binding site was called 5-HT1C because of its very high affinity for 5-HT itself. Within the following 10 years, the 5-HT1CR (later named 5- HT2C) was extensively characterised pharmacologically, anatomically and functionally: it was one of the first 5-HT receptors to be sequenced and cloned. The 5-HT2CR is a GPCR, with a very complex gene structure. It constitutes a rarity in theGPCR family: many 5-HT2CR variants exist, especially in humans, due to RNA editing, in addition to a few 5-HT2CR splice variants. Intense research led to therapeutically active 5-HT2C receptor ligands, both antagonists (or inverse agonists) and agonists: keeping in mind that a number of antidepressants and antipsychotics are 5- HT2CR antagonists/inverse agonists. Agomelatine, a 5-HT2CR antagonist is registered for the treatment of major depression. The agonist Lorcaserin is registered for the treatment of aspects of obesity and has further potential in addiction, especially nicotine/ smoking. There is good evidence that the 5-HT2CR is involved in spinal cord injury-induced spasms of the lower limbs, which can be treated with 5-HT2CR antagonists/inverse agonists such as cyproheptadine or SB206553. The 5-HT2CR may play a role in schizophrenia and epilepsy. Vabicaserin, a 5-HT2CR agonist has been in development for the treatment of schizophrenia and obesity, but was stopped. As is common, there is potential for further indications for 5-HT2CR ligands, as suggested by a number of preclinical and/or genome-wide association studies (GWAS) on depression, suicide, sexual dysfunction, addictions and obesity. The 5-HT2CR is clearly affected by a number of established antidepressants/antipsychotics and may be one of the culprits in antipsychotic-induced weight gain

Adaptive Resonance Theory-Based Neural Networks - the Art of Real-Time Pattern-Recognition in Chemical Process Monitoring

Contains fulltext : 28844.pdf (publisher's version ) (Open Access

Adaptive resonance theory based neural network for supervised chemical pattern recognition (FuzzyARTMAP) .1. Theory and network properties

Contains fulltext : 28845.pdf (publisher's version ) (Open Access