58 research outputs found

    The Possibility of Using of the Fuzzy Logic in the Firms

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    Fuzzy logika je komplexní nástroj pro podporu rozhodování v nejrůznějších oblastech využití. Tato diplomová práce si klade za cíl analyzovat dosavadní způsoby vybraných rozhodovacích procesů ve firmě a následně navrhnout efektivnější způsoby rozhodování za použití nástrojů fuzzy logiky.Fuzzy logic is a complex tool for support for decision-making in various arrays of use. This thesis should analyze existing solutions in selected decision processes in companies and to bring more effective ways of decision-making using fuzzy logic in consequence.

    Design and Creation of Software Application for the Company Obicentrum spol. s r.o.

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    Tato bakalářská práce je zaměřena na analýzou současného stavu firmy OBI Centrum, spol. s r.o., která se zabývá výrobou a montáží komínů a komínových částí a dále analýzou informačního systému této firmy. Práce je rozdělena do tří částí. V první části jsou rozebrána teoretická východiska. Druhá část se zabývá analýzou současného stavu, kde je zhodnocen stav informačního systému, a také firma obecně. V poslední části je navržené vlastní řešení problému, který byl odhalen pomocí analýz.The thesis is focused on analysing the current situation of OBI Centrum, spol. s r.o., company engaged in manufacturing and assembling of chimneys and chimney parts and on analysing the information system of the company. The thesis is divided into three parts. The first part addresses the theoretical bases. The second part analyses the current situation of the company, evaluating the quality of informational system and the company in general. The last part presents a proposed solution to the problem revealed by the analysis.

    Information System Assessment and Proposal of ICT Modification

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    Tato diplomová práce je zaměřena na analýzu současného stavu rodinného obchodu, který se zabývá prodejem potřeb a krmiv pro zvířata a dále analýzou informačního systému této firmy a návrhem jeho zlepšení za účelem podpory prodeje firmy. Práce je rozdělena do tří částí. V první části jsou rozebrána teoretická východiska. Druhá část se zabývá analýzou současného stavu, kde je zhodnocen stav informačního systému, a také obchod samotný. Obsahem praktické části je návrh na zavedení systému pro podporu prodeje prostřednictvím elektronického obchodování.The thesis is focused on the current situation and the information system analysis of the particular retail, which deals with the sale of animal feed and supplies. Furthermore, it provides the improvement proposal, in order to support company sales. The thesis is divided into three parts. The first part determines the theoretical basis. The second part analyses the current situation of the company, evaluates the quality of its information system and the company in general. The content of the practical part is a proposal of a sales promotion system through e-commerce.

    4245 Visual field examination via motion-onset VEPs

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    Neural Correlates of Liberalism and Conservatism in a Post-communist Country

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    A previous experiment showed that there was a strong correlation between conservatism/liberalism and brain activity, linked to an error response (r = 0.59, p < 0.001) in the USA political environment. We re-ran the experiment on a larger and age-homogeneous group (n = 100, 50 females and 50 males, aged 20–26 years) in the Czech Republic; a European country with a different sociocultural environment and history. We did not find a relationship between the brain activity connected to conflict monitoring and self-reported conservatism/liberalism orientation (ρ = −0.11, p = 0.297) or conservatism/liberalism validated for the USA agenda (ρ = −0.01, p = 0.910). Instead of replicating the previous study, we decided to test the hypothesis under a different socio-cultural context. Our results support a view of self-reported or validated, conservative or liberal attitudes as a complex behavioral pattern. Such a behavioral pattern cannot be determined with statistical significance, using a simple Go-NoGo detection task, without accounting for confounding factors such as age and socio-cultural conditions. Sufficiently powered studies are warranted to evaluate this neuro-political controversy

    Spared cognitive processing of visual oddballs despite delayed visual evoked potentials in patient with partial recovery of vision after 53years of blindness

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    AbstractWe examined the visual and cognitive functions of a 72-year-old subject, KP, who recovered his sight after 53years of visual deprivation. We used visual evoked potentials (VEPs) to pattern-reversal and motion-onset stimuli and cognitive responses (ERPs) during the oddball paradigm to assess the effect of long-term deprivation on a mature visual system. KP lost his sight at the age of 17years, and light projection onto his right retina was restored at 71years by a corneal implant. Nine months after sight recovery we recorded reproducible responses to all examined stimuli. The response to pattern reversal contained two P100-like peaks with the later peak being dominant and significantly delayed (260ms) when compared to the P100s of two control subjects, to whom the stimuli were adjusted in size and contrast to mimic KP’s vision. KP’s motion-onset VEPs to full-field and peripheral stimuli had a characteristic shape with a well-defined N2 peak; however, both peaks were significantly delayed (262 and 272ms) compared to control responses. Unlike the P100 and N2 peaks, which represent sensory detection, the P3b/P300 component of the ERP to a target event in the oddball paradigm was not further delayed. In spite of degraded vision and sensory deprivation lasting 53years, KP displayed reproducible responses to all reported stimuli. Long-term visual deprivation and retinal detachment degraded KP’s visual sensory processing, assessed by pattern-reversal and motion-onset VEPs, whereas the cognitive processing of appropriate visual stimuli was not compromised

    Mechanical properties of a biodegradable self-expandable polydioxanone monofilament stent: In vitro force relaxation and its clinical relevance

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    Biodegradable stents are promising treatments for many diseases, e.g., coronary artery disease, urethral diseases, tracheal diseases, and esophageal strictures. The mechanical properties of biodegradable stent materials play a key role in the safety and efficacy of treatment. In particular, insufficient creep resistance of the stent material could result in premature stent collapse or narrowing. Commercially available biodegradable self-expandable SX-ELLA stents made of polydioxanone monofilament were tested. A new, simple, and affordable method to measure the shear modulus of tiny viscoelastic wires is presented. The important mechanical parameters of the polydioxanone filament were obtained: the median Young's modulus was (E) over tilde = 958 (922, 974) MPa and the shear modulus was (G) over tilde= 357 (185, 387) MPa, resulting in a Poisson's ratio of nu = 0.34. The SX-ELLA stents exhibited significant force relaxation due to the stress relaxation of the polydioxanone monofilament, approximately 19% and 36% 10 min and 48 h after stent application, respectively. However, these results were expected, and the manufacturer and implanting clinician should be aware of the known behavior of these biodegradable materials. If possible, a biodegradable stent should be designed considering therapeutic force rather than initial force. Additionally, new and more advanced biodegradable shape-memory polymers should be considered for future study and use

    Visual mismatch negativity (vMMN): A review and meta-analysis of studies in psychiatric and neurological disorders

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    The visual mismatch negativity (vMMN) response is an event-related potential (ERP) component, which is automatically elicited by events that violate predictions based on prior events. VMMN experiments use visual stimulus repetition to induce predictions, and vMMN is obtained by subtracting the response to rare unpredicted stimuli from those to frequent stimuli. One increasingly popular interpretation of the mismatch response postulates that vMMN, similar to its auditory counterpart (aMMN), represents a prediction error response generated by cortical mechanisms forming probabilistic representations of sensory signals. Here we discuss the physiological and theoretical basis of vMMN and review thirty-three studies from the emerging field of its clinical applications, presenting a meta-analysis of findings in schizophrenia, mood disorders, substance abuse, neurodegenerative disorders, developmental disorders, deafness, panic disorder and hypertension. Furthermore, we include reports on aging and maturation as they bear upon many clinically relevant conditions. Surveying the literature we found that vMMN is altered in several clinical populations which is in line with aMMN findings. An important potential advantage of vMMN however is that it allows the investigation of deficits in predictive processing in cognitive domains which rely primarily on visual information; a principal sensory modality and thus of vital importance in environmental information processing and response, and a modality which arguably may be more sensitive to some pathological changes. However, due to the relative infancy of research in vMMN compared to aMMN in clinical populations its potential for clinical application is not yet fully appreciated. The aim of this review and meta-analysis therefore is to present, in a detailed systematic manner, the findings from clinically-based vMMN studies, to discuss their potential impact and application, to raise awareness of this measure and to improve our understanding of disease upon fundamental aspects of visual information processing
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