Kindergarten

The subject of this thesis is the preparation of documentation for the construction of a new kindergarten in Prague 6. It is a two-story building. The kindergarten is located to the north of the residential area of Vokovice. The area of the proposed development is flat. The plot is currently undeveloped. The future building will be situated near a forest. The kindergarten consists of two departments for preschool children with a capacity of 2 × 24 children. The main entrance to the building is located on the eastern facade of the first floor. Here, there is also a children’s changing room, playroom, washroom, and toilets for children, staff changing room with WC, cleaning room, and a meal distribution area. The same facilities are located on the second floor. The second floor is supplemented with staff facilities, such as changing rooms and an office. Additionally, there is a classroom that can serve various purposes. The classrooms are designed as spaces that can be divided by a movable partition into a playroom and a bedroom. The flat roof is planted with extensive greenery, which improves the building’s energy efficiency and promotes a connection with the surrounding nature. The new building is accompanied by a parking lot and play areas with play equipment. The building is founded on a reinforced concrete slab combined with foundation strips. The vertical load-bearing structures of the above-ground part of the building are made of ceramic masonry. The ceiling structure consists of a monolithic reinforced concrete slab. The facade is made of vertical wooden strips and plastic windows with an oak stain to better blend in with the nature

Design of reinforced concrete structure

This thesis focuses on two variants of the ceiling slab for the extension of the 5th floor. The first variant is a monolithic ceiling slab, which is lightened using U-Boot formwork. The second variant is the design of a beam ceiling. The next part of the thesis assesses the existing vertical structures, where it was necessary to design reinforcement for the internal columns using FRP wrapping. The outcome of the thesis is a static calculation, a shape drawing, and reinforcement details. The calculations were performed using Scia Engineer 24.0, while the design of the wrapping reinforcement was calculated using Sika Carbodur V7.0. The drawing documentation was created using AutoCAD 2023 and CADKON RC+ 2025 software

Possibilities of using alternative lightening agents in modern masonry elements production

This master´s thesis explores the potential use of alternative lightweight materials derived from easily renewable and secondary raw materials for the production of modern ceramic masonry wall fittings. The primary objective is to identify a viable alternative to the most commonly used lightweight burning material, wood sawdust. The thesis further examines the incorporation of the selected alternative lightweight material into a brick mixture and seeks to determine an optimal replacement ratio for sawdust that could be implemented and tested in industrial production. Finally, the thesis evaluates the availability, economic feasibility, and ecological impact of substituting sawdust with an alternative lightweight material

Cat Centre

The aim of this Master’s thesis is to develop project documentation of a new nearly-zero energy Cat Centre building in Brno-Bystrc. The building was designed as detached and has one above-ground floor. It has four functional units: a cat shelter, cat café, veterinary office and a pet supply shop. The building plot is accessible by local road and is slightly sloping. The thesis has three parts. The first part presents structural and architectural design and also building physics assessment. The second part presents the design of building services – ventilation, heating, mechanical, electrical, plumbing and rainwater management. The external and internal load-bearing walls are designed as a masonry system from adobe-clay bricks. The facade is designed as ventilated with a ventilated air gap and is thermally insulated with mineral wool. The partition walls are made of plasterboard. The floor structure is a foundation slab. The roof is designed as a flat green roof which floats over timber framing. The house has mechanical ventilation. It is heated by floor heating with district heating as the heat source. The building is cooled by air conditioning units with heat pump as the cold source. 57 photovoltaic panels are installed on the roof of the building providing electricity. The rainwater is collected from roofs and is used for watering greenery and maintenance of sidewalks. The Energy Performance Certificate was developed. The third part of the Master’s thesis deals with the Life-Cycle assessment (LCA) of six different compositions of ventilated facades. These compositions differ from each other in the type of fibrous thermal insulation material, load-bearing structure and the type of cladding layer. A wall area of 1 m2 with a heat transfer coefficient of U = 0.168 W/ (m2.K) was chosen as the functional unit for the LCA. OneClickLCA software was used in the calculations. A life cycle model was created for each component, including the different phases and modules defined in EN 15978

Production hall CLT Ždírec nad Doubravou - construction technological project

The content of the diploma thesis "Production Hall CLT Ždírec nad Doubravou - construction-technological project" is a general construction-technological solution of the building. This thesis includes the technological regulation, technical report, site equipment, design of machine assembly, time schedule, budget, inspection and test plan, safety at work, noise protection and environmental protection

The Impact of Sustainability on the Decision-making of a Member of a Governing Body

The Impact of Sustainability on the Decision-making of a Member of a Governing Body Abstract This master's thesis analyses the impact of sustainability on the decision-making processes of members of governing bodies, with particular emphasis on their duty to act with due managerial care under Section 159 of the Civil Code. The first chapter of this thesis defines the legal framework for sustainability and distinguishes the concepts of CSR (Corporate Social Responsibility) and ESG (Environmental, Social, and Governance). It also outlines the sub-areas of sustainability - environmental, social, economic, and corporate governance dimensions, which should be approached with equal importance. The second chapter delves into the prerequisites for sustainability-focused decision- making. It provides an overview of the legal framework governing sustainability within various legal instruments, including both direct obligations that incorporate sustainability considerations and incentives such as tax reductions and other benefits aimed at fostering a transition to sustainable business practices. This section offers a non-exhaustive overview of relevant legal provisions in the Czech legal system while also reflecting on sustainability requirements in foreign jurisdictions. In this context, it addresses the potential..

Predictors of work burnout and engagement: Study on a sample of czech population in a private sector

The key theme of the thesis is the exploration of working conditions as predictors of mental health in the workplace. The literature review first focuses on the theoretical framework of occupational well-being, with an emphasis on job burnout and engagement. Special attention in the second part is given to the Job Demands-Resources (JD-R) theory, which also forms the basis of the empirical section. The thesis outlines the evolution of the model in time and its capacity to explain the complex mechanisms of working conditions and their impact on employees' occupational well-being. The empirical section aims to quantitatively validate the JD-R theory within the working Czech population in the business sector. Beyond work demands metrics, burnout was predicted by work-life conflict and perceived stress. Engagement, in addition to job resources, was also predicted by team autonomy and coaching-oriented leadership. The results, using structural modeling, confirm the fundamental propositions of the JD-R model, with all work demands being capable of predicting burnout and nearly all job resources being significant predictors of engagement. The only predictor that did not show a significant impact on mental health was coaching-oriented leadership. The research contributes to a deeper understanding of the..

Effect of amyloid β-42 on the expression of membrane receptors during differentiation of the SH-SY5Y cell line

Amyloid β (Aβ) is the product of amyloidogenic cleavage of its precursor protein (APP) by β and γ secretases. According to the amyloid hypothesis, Aβ plays a key role in the early pathogenesis of Alzheimer's disease (AD), the world's most common neurodegenerative disease for which there is currently no effective treatment. Aβ oligomers, particularly the Aβ42 form, induce synaptic dysfunction, oxidative stress, inflammation and disruption of calcium homeostasis. These processes lead to progressive neuronal and cognitive loss. It exerts its toxic effects directly by disrupting membrane integrity and neuronal function, or indirectly via inflammatory mediators by activating microglia and astrocytes. Aβ has the ability to bind to several cell surface receptors. This work focuses on studying the toxicity of Aβ-42 oligomers on the human SH-SY5Y cell line, specifically its effect on the expression of various biomarkers during retinoic acid- induced differentiation. The results confirm the toxic effect of Aβ-42 on the cell viability of the SH-SY5Y cell line and its ability to influence the expression of several proteins during differentiation

Design of load-bearing structure of the hospital building in Zlín

The diploma thesis deals with the design of the load-bearing structure of a part of the building of the Tomáš Bat'a Regional Hospital in Zlín and the assessment of selected structures including drawing documentation of these individual elements. The building is designed as a reinforced concrete monolithic skeleton structure based on a foundation slab. The subsequent assessment deals with the foundation structures – the foundation slab and basement walls, the ceiling slab of a typical floor including the perimeter beam, columns on each floor, selected staircase and the construction of the heliport located on the roof of the designed part of the building. The computational models from which the internal forces were obtained were created in SCIA Engineer 22.0. The thesis includes a text section with an introduction about the intended project and a technical report, a structural calculation, drawings and annexes to the structural calculation. The thesis was prepared in accordance with the applicable standards and regulations